#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17967	uniprotkb:P17967	intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C	intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C	psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name)	psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Tian et al. (2006)	pubmed:16413482|imex:IM-11817	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-908291|rcsb pdb:2B5E|imex:IM-11817-1	-	-	psi-mi:"MI:0503"(self)	psi-mi:"MI:0503"(self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042	refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042	imex:IM-174(imex secondary)	crc64:69CF3E05D7F74C94	crc64:69CF3E05D7F74C94	3d-resolution:2.4 A|3d-r-factors:"0.191 (Rfree = 0.247)"|3d-structure:The structure looks like an 'U' with the a and a prime being the top of the letter U and the bend of the U being the regions b and b prime. The dimensions are 80A for width and 60A for height. Each of the a, a prime, b and b prime adopt a thioredoxin fold. In the crystal the b domain of a symmetry-related molecule extensively interacts with the a domain.|3d-structure:Four PDI molecules form a tetramer around a crystallographic 4-fold axis of symmetry.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/21	2014/10/16	rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292	rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292	intact-crc:E7C074E12B5990A6|rigid:jX1B2SuRAkXmOVvw54mX53z631U	false	sufficient binding region:23-522|binding-associated region:90-97|binding-associated region:61-64	sufficient binding region:23-522|binding-associated region:90-97|binding-associated region:61-64	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)