#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48561	uniprotkb:P47047	intact:EBI-19525|uniprotkb:D6W0P5|ensemblfungi:YNL299W	intact:EBI-11592|uniprotkb:D6VWD3|ensemblfungi:YJL050W	psi-mi:trf5_yeast(display_long)|uniprotkb:TRF5(gene name)|psi-mi:TRF5(display_short)|uniprotkb:YNL299W(locus name)|uniprotkb:N0440(orf name)|uniprotkb:Topoisomerase 1-related protein TRF5(gene name synonym)	psi-mi:mtr4_yeast(display_long)|uniprotkb:MTR4(gene name)|psi-mi:MTR4(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:YJL050W(locus name)|uniprotkb:J1158(orf name)|uniprotkb:mRNA transport regulator MTR4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Houseley et al. (2006)	pubmed:16374505|mint:MINT-5218164|imex:IM-10995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-2206291|imex:IM-10995-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014100.2|sgd:S000005243|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR002058(PAP/25A-associated)|ensemblfungi:YNL299W(gene)|ensemblfungi:YNL299W_mRNA(transcript)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|mint:P48561|interpro:IPR043519	ensemblfungi:YJL050W(gene)|ensemblfungi:YJL050W_mRNA(transcript)|go:"GO:0000292"(RNA fragment catabolic process)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011254(Prismane-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|rcsb pdb:2XGJ|rcsb pdb:4QU4|rcsb pdb:4U4C|rcsb pdb:4WFD|rcsb pdb:5OOQ|rcsb pdb:6FSZ|rcsb pdb:6FT6|rcsb pdb:6LQS|rcsb pdb:7AJT|rcsb pdb:7AJU|reactome:R-SCE-6791226|refseq:NP_012485.1|sgd:S000003586|mint:P47047|dip:DIP-6394N	-	-	crc64:1FA9EAADC546F669	figure legend:Fig 4E|comment:Rpl2B and Ccp1 were also identified but are abundant proteins that are likely to be contaminants.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/07	2014/10/16	rogid:LGAMmHC1JOdurgO0HZ17ndGKZn8559292	rogid:4kk4g0guPbSu0AyK9nVaY/w2W2U559292	intact-crc:22C1DB8BC336DCFF|rigid:i7eB1E9ukF4ccHCg9zf1Nvg075E	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P48561	uniprotkb:P40507	intact:EBI-19525|uniprotkb:D6W0P5|ensemblfungi:YNL299W	intact:EBI-25083|uniprotkb:D6VVK5|ensemblfungi:YIL079C	psi-mi:trf5_yeast(display_long)|uniprotkb:TRF5(gene name)|psi-mi:TRF5(display_short)|uniprotkb:YNL299W(locus name)|uniprotkb:N0440(orf name)|uniprotkb:Topoisomerase 1-related protein TRF5(gene name synonym)	psi-mi:air1_yeast(display_long)|uniprotkb:Arginine methyltransferase-interacting RING finger protein 1(gene name synonym)|uniprotkb:AIR1(gene name)|psi-mi:AIR1(display_short)|uniprotkb:YIL079C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Houseley et al. (2006)	pubmed:16374505|mint:MINT-5218164|imex:IM-10995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-2206291|imex:IM-10995-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014100.2|sgd:S000005243|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR002058(PAP/25A-associated)|ensemblfungi:YNL299W(gene)|ensemblfungi:YNL299W_mRNA(transcript)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|mint:P48561|interpro:IPR043519	refseq:NP_012186.1|sgd:S000001341|mint:P40507|dip:DIP-2700N|ensemblfungi:YIL079C(gene)|ensemblfungi:YIL079C_mRNA(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031499"(TRAMP complex)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0071031"(nuclear mRNA surveillance of mRNA 3'-end processing)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR016713("Poly(A) polymerase complex, Air1/2")|interpro:IPR036875	-	-	crc64:3CA920FA1204EC9C	figure legend:Fig 4E|comment:Rpl2B and Ccp1 were also identified but are abundant proteins that are likely to be contaminants.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/07	2014/10/16	rogid:LGAMmHC1JOdurgO0HZ17ndGKZn8559292	rogid:myPxXwP+mJgvoh50PLYk2Q3GMh4559292	intact-crc:22C1DB8BC336DCFF|rigid:i7eB1E9ukF4ccHCg9zf1Nvg075E	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P48561	intact:EBI-2133369	intact:EBI-19525|uniprotkb:D6W0P5|ensemblfungi:YNL299W	-	psi-mi:trf5_yeast(display_long)|uniprotkb:TRF5(gene name)|psi-mi:TRF5(display_short)|uniprotkb:YNL299W(locus name)|uniprotkb:N0440(orf name)|uniprotkb:Topoisomerase 1-related protein TRF5(gene name synonym)	psi-mi:polya_rna(display_short)|psi-mi:EBI-2133369(display_long)	psi-mi:"MI:0415"(enzymatic study)	Houseley et al. (2006)	pubmed:16374505|mint:MINT-5218164|imex:IM-10995	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0414"(enzymatic reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-2264701|imex:IM-10995-2	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_014100.2|sgd:S000005243|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR002058(PAP/25A-associated)|ensemblfungi:YNL299W(gene)|ensemblfungi:YNL299W_mRNA(transcript)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|mint:P48561|interpro:IPR043519	-	go:"GO:0043631"(RNA polyadenylation)|go:"GO:0034062"(5'-3' RNA polymerase activity)	-	-	figure legend:Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/07	2014/10/16	rogid:LGAMmHC1JOdurgO0HZ17ndGKZn8559292	-	intact-crc:7F6F731F83D3DCBD	false	calmodulin binding peptide plus protein a tag:c-c|calmodulin binding peptide plus protein a tag:c-c|mutation decreasing interaction:235-235,233-233	-	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)