#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NPI6 uniprotkb:Q6P2E9 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:10EC7FCE48A98076|rigid:pkUSvgPnw+0e8cl+yW9z/d6dtfA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPI6 uniprotkb:Q9NPI6 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:10EC7FCE48A98076|rigid:pkUSvgPnw+0e8cl+yW9z/d6dtfA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPI6 uniprotkb:Q96F86 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:10EC7FCE48A98076|rigid:pkUSvgPnw+0e8cl+yW9z/d6dtfA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPI6 uniprotkb:P26196 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:10EC7FCE48A98076|rigid:pkUSvgPnw+0e8cl+yW9z/d6dtfA false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8IZD4 uniprotkb:P34931 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - caution:"A chaperone protein, HSPA1L, which copurified with FLAG-hDcp1a and FLAG-hDcp1b, is presumed to be a nonspecific interactor (Figure 1A)."|figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:E49E4F0672F243E2|rigid:1xQSFVpGMW9YjeyK4au2oa60D7Q false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8IZD4 uniprotkb:Q8IZD4 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - caution:"A chaperone protein, HSPA1L, which copurified with FLAG-hDcp1a and FLAG-hDcp1b, is presumed to be a nonspecific interactor (Figure 1A)."|figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:E49E4F0672F243E2|rigid:1xQSFVpGMW9YjeyK4au2oa60D7Q false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8IZD4 uniprotkb:Q96F86 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - caution:"A chaperone protein, HSPA1L, which copurified with FLAG-hDcp1a and FLAG-hDcp1b, is presumed to be a nonspecific interactor (Figure 1A)."|figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:E49E4F0672F243E2|rigid:1xQSFVpGMW9YjeyK4au2oa60D7Q false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8IZD4 uniprotkb:P26196 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-997513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - caution:"A chaperone protein, HSPA1L, which copurified with FLAG-hDcp1a and FLAG-hDcp1b, is presumed to be a nonspecific interactor (Figure 1A)."|figure legend:1A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:E49E4F0672F243E2|rigid:1xQSFVpGMW9YjeyK4au2oa60D7Q false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9NPI6 uniprotkb:Q96F86 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008342 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:1C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:522607B26EC85A69|rigid:ZVf9GfxHTd9yai+UZRMnjfNpVNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q6P2E9 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1008342 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:1C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:522607B26EC85A69|rigid:ZVf9GfxHTd9yai+UZRMnjfNpVNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q6P2E9 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:3A taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:454BDDC3698B74F3|rigid:ZLMvm3ImEkySqF7qH21/PtmAWGI false - myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q96F86 uniprotkb:Q9NPI6 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:"3A:7-9" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:B1F92953F9EB42AD|rigid:17rfpzN0ucUTAoQFSe7Vgt2CIzs false myc tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q8IZD4 uniprotkb:Q9NPI6 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:"3A:10-12" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:44DC8E252B312A2D|rigid:ONDAq8uh2q2wZLABBQhTH1U4yc8 false myc tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9NPI6 uniprotkb:P26196 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:"3A:4-6" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:A50D93406B996980|rigid:SZ34/lgQQ3QwKoyFTodbLPzR0Eo false - myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6P2E9 uniprotkb:Q9NPI6 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:"3B:1-3" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:B2C495EC865271C8|rigid:ZLMvm3ImEkySqF7qH21/PtmAWGI false - myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9NPI6 uniprotkb:Q6P2E9 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006344 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:"3C:13-16" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:37B89C387E0049F8|rigid:AdqsslsD41NfvcL0KC+9ylPwPRg false - myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9NPI6 uniprotkb:Q8IZH2 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-372406|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39|ensembl:ENSP00000264951 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1006344 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|ensembl:ENSG00000114127(gene)|ensembl:ENST00000264951(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033574"(response to testosterone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1905795"(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|dip:DIP-31174N - - - figure legend:"3C:13-16" taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606 intact-crc:37B89C387E0049F8|rigid:AdqsslsD41NfvcL0KC+9ylPwPRg false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9NPI6 uniprotkb:Q6P2E9 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006051 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:2A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:E89FCEDDD7C84530|rigid:M+d/hVDOFgzYPX21VLj5xOpCf98 false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q8IU60-1 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-521586|ensembl:ENSP00000373715 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:q8iu60-1(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006051 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N intact:EBI-521577(dcp2_human)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript) - - - figure legend:2A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:E89FCEDDD7C84530|rigid:M+d/hVDOFgzYPX21VLj5xOpCf98 false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P2E9 uniprotkb:Q8IU60 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006072 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:Figure 2A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:D8389E9EE1496BE0|rigid:gXypVK8KE+rkqBYPh7UkAf903bk false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P2E9 uniprotkb:Q8IU60 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:Figure 2A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:38CF0AA004473AD1|rigid:M+d/hVDOFgzYPX21VLj5xOpCf98 false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P2E9 uniprotkb:Q9NPI6 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure 2A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:38CF0AA004473AD1|rigid:M+d/hVDOFgzYPX21VLj5xOpCf98 false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26651 uniprotkb:Q9NPI6 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure 5A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:C1E0AF9CD424D3F0|rigid:82mDa0gSTp3ms/asucRpVd/GNlY false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q92900 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 5A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:FA7A450FAB4DC629|rigid:INS9U2McTC52mz58j/5dv+PSDZk false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-1 uniprotkb:P26651 intact:EBI-521586|ensembl:ENSP00000373715 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 psi-mi:q8iu60-1(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N - - - figure legend:Figure 5A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 intact-crc:59795A901A787D82|rigid:onRd3SPyXfORXKFKDZhaIDAO+tI false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60 uniprotkb:Q92900 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Figure 5A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:E813DFECD568050C|rigid:AVe1mo9GeDV+iIwFeN3H/a3LGXA false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:P26651 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006636 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N - - - figure legend:Figure 5A taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 intact-crc:FEB78EDD7B7364CF|rigid:b84HBaMGe40+lEnKzViHSkNA7P0 false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92900 uniprotkb:Q8IU60-2 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-521590|ensembl:ENSP00000425770 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006676 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 intact-crc:8B9875B01A2F73E8|rigid:gWDt7eVT3hEKKHvgwAa/zxQn2qo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92900 uniprotkb:Q6P2E9 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006676 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:8B9875B01A2F73E8|rigid:gWDt7eVT3hEKKHvgwAa/zxQn2qo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92900 uniprotkb:Q96F86 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006676 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:8B9875B01A2F73E8|rigid:gWDt7eVT3hEKKHvgwAa/zxQn2qo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92900 uniprotkb:Q9NPI6 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006676 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:8B9875B01A2F73E8|rigid:gWDt7eVT3hEKKHvgwAa/zxQn2qo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26651 uniprotkb:Q8IU60-2 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-521590|ensembl:ENSP00000425770 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006825 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 intact-crc:5EE3363F8C4E7C02|rigid:kWW+z5/0ZGa8S8zkg7hplDhnG2Y false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26651 uniprotkb:Q6P2E9 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006825 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:5EE3363F8C4E7C02|rigid:kWW+z5/0ZGa8S8zkg7hplDhnG2Y false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26651 uniprotkb:Q96F86 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006825 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:5EE3363F8C4E7C02|rigid:kWW+z5/0ZGa8S8zkg7hplDhnG2Y false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26651 uniprotkb:Q9NPI6 intact:EBI-374248|intact:EBI-28988987|ensembl:ENSP00000469647|uniprotkb:B2RA54 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:ttp_human(display_long)|uniprotkb:ZFP36(gene name)|psi-mi:ZFP36(display_short)|uniprotkb:G0S24(gene name synonym)|uniprotkb:TIS11A(gene name synonym)|uniprotkb:TTP(gene name synonym)|uniprotkb:Growth factor-inducible nuclear protein NUP475(gene name synonym)|uniprotkb:G0/G1 switch regulatory protein 24(gene name synonym)|uniprotkb:NUP475(gene name synonym)|uniprotkb:Tristetraprolin(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:RNF162A(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006825 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128016(gene)|ensembl:ENST00000597629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009611"(response to wounding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042594"(response to starvation)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901835"(positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:1902172"(regulation of keratinocyte apoptotic process)|go:"GO:1904246"(negative regulation of polynucleotide adenylyltransferase activity)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|rcsb pdb:4J8S|reactome:R-HSA-450513|refseq:NP_003398.2|ensembl:ENSP00000469647|dip:DIP-29845N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure 6B taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:gDx8zP1NQwjgu7oJZg3sneBZnaI9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:5EE3363F8C4E7C02|rigid:kWW+z5/0ZGa8S8zkg7hplDhnG2Y false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:P26196 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006852 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:D8C202ACD8172015|rigid:ZgE22mFipzNt1aM7oDxIkDFOkic false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q6P2E9 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006852 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:D8C202ACD8172015|rigid:ZgE22mFipzNt1aM7oDxIkDFOkic false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q8IU60-2 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-521590|ensembl:ENSP00000425770 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006852 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 intact-crc:D8C202ACD8172015|rigid:ZgE22mFipzNt1aM7oDxIkDFOkic false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q9NPI6 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006852 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:D8C202ACD8172015|rigid:ZgE22mFipzNt1aM7oDxIkDFOkic false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q9NPI6 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006874 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N intact:EBI-1163839(intact-secondary) - - figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:C9EF09B11B497671|rigid:VknmO0iTIIg15J1eJXkfNR/NKZE false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q6P2E9 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006874 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N intact:EBI-1163839(intact-secondary) - - figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:C9EF09B11B497671|rigid:VknmO0iTIIg15J1eJXkfNR/NKZE false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96F86 uniprotkb:Q8IU60-2 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 intact:EBI-521590|ensembl:ENSP00000425770 psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006874 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) intact:EBI-1163839(intact-secondary) - isoform-comment:No experimental confirmation available. figure legend:Figure 6C taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 intact-crc:C9EF09B11B497671|rigid:VknmO0iTIIg15J1eJXkfNR/NKZE false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-1 uniprotkb:Q8IU60 intact:EBI-521586|ensembl:ENSP00000373715 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:q8iu60-1(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006934 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript) refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:FAB3391DEA40050F|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-1 uniprotkb:Q9NPI6 intact:EBI-521586|ensembl:ENSP00000373715 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:q8iu60-1(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006934 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:FAB3391DEA40050F|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-1 uniprotkb:Q8IZD4 intact:EBI-521586|ensembl:ENSP00000373715 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:q8iu60-1(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006934 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:FAB3391DEA40050F|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q8IU60 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006949 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:C2815CD67691824C|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q9NPI6 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006949 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:C2815CD67691824C|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q8IZD4 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006949 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:C2815CD67691824C|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q8IU60 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006973 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:A1F4D8E876BE7BCE|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q9NPI6 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006973 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:A1F4D8E876BE7BCE|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q8IZD4 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1006973 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:Figure S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:A1F4D8E876BE7BCE|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q8IU60 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162602 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:EF6BFA50C52CD068|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q9NPI6 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162602 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:EF6BFA50C52CD068|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IZD4 uniprotkb:Q8IZD4 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162602 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:EF6BFA50C52CD068|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-2 uniprotkb:Q9NPI6 intact:EBI-521590|ensembl:ENSP00000425770 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162630 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - isoform-comment:No experimental confirmation available. - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:F2F8A5FA24E92DCB|rigid:rVEPZHP8NOkhY0dc33lENMZrpi8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-2 uniprotkb:Q8IU60 intact:EBI-521590|ensembl:ENSP00000425770 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162630 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - isoform-comment:No experimental confirmation available. - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:F2F8A5FA24E92DCB|rigid:rVEPZHP8NOkhY0dc33lENMZrpi8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-2 uniprotkb:Q8IZD4 intact:EBI-521590|ensembl:ENSP00000425770 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162630 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - isoform-comment:No experimental confirmation available. - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:F2F8A5FA24E92DCB|rigid:rVEPZHP8NOkhY0dc33lENMZrpi8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q8IZD4 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162641 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 intact-crc:4873A1F83E6C46F0|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q9NPI6 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162641 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:4873A1F83E6C46F0|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q8IU60 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162641 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 - - - figure legend:S2 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 intact-crc:4873A1F83E6C46F0|rigid:mmvGJIFTdK1jPco+r1baucIK3Wg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26196 uniprotkb:Q9NPI6 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162736 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:S6 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:AE91430EC783675B|rigid:SZ34/lgQQ3QwKoyFTodbLPzR0Eo false flag tag:n-n myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26196 uniprotkb:Q96F86 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162980 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:S6 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2014/10/16 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 intact-crc:BB79DE65090B2F15|rigid:X+qeIcKghE7sNZ58fv5eABCzTpY false myc tag:?-? flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:P26196 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1163041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:S6 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:E015AC0E0A16F520|rigid:SZ34/lgQQ3QwKoyFTodbLPzR0Eo false flag tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60 uniprotkb:Q6P2E9 intact:EBI-521577|uniprotkb:Q6P2D4|uniprotkb:Q7Z5W5|uniprotkb:Q8NBG5|uniprotkb:C9J778|ensembl:ENSP00000373715 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:dcp2_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1163129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229306.1|refseq:NP_689837.2|dip:DIP-31126N|ensembl:ENSG00000172795(gene)|ensembl:ENST00000389063(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0016896"(exoribonuclease activity, producing 5'-phosphomonoesters)|go:"GO:0030054"(cell junction)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR007722(Dcp2, box A)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR036189|interpro:IPR044099|rcsb pdb:5MP0|rcsb pdb:5QOH|rcsb pdb:5QOI|rcsb pdb:5QOJ|rcsb pdb:5QOK|rcsb pdb:5QOL|rcsb pdb:5QOM|rcsb pdb:5QON|rcsb pdb:5QOO|rcsb pdb:5QOP|rcsb pdb:5QOQ|rcsb pdb:5QOR|rcsb pdb:5QOS|rcsb pdb:5QOT|rcsb pdb:5QOU|rcsb pdb:5QOV|rcsb pdb:5QOW|rcsb pdb:5QOX|rcsb pdb:5QOY|rcsb pdb:5QOZ|rcsb pdb:5QP0|rcsb pdb:5QP1|rcsb pdb:5QP2|rcsb pdb:5QP3|rcsb pdb:5QP4|rcsb pdb:5QP5|rcsb pdb:5QP6|rcsb pdb:5QP7|rcsb pdb:5QP8|rcsb pdb:5QP9|rcsb pdb:5QPA|rcsb pdb:5QPB|rcsb pdb:5QPC|reactome:R-HSA-380994|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604 ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:S6 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:3Bo/mLVHBcFZ4VmRqgvE2PWTw+Y9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:9EE43ADD47C4C8F8|rigid:gXypVK8KE+rkqBYPh7UkAf903bk false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IU60-2 uniprotkb:Q6P2E9 intact:EBI-521590|ensembl:ENSP00000425770 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:q8iu60-2(display_long)|uniprotkb:DCP2(gene name)|psi-mi:DCP2(display_short)|uniprotkb:NUDT20(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 20(gene name synonym)|uniprotkb:mRNA-decapping enzyme 2(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1163894 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-521577(dcp2_human)|uniprotkb:Q8IU60-2(isoform-parent)|ensembl:ENSG00000172795(gene)|ensembl:ENST00000515408(transcript) ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - isoform-comment:No experimental confirmation available. - figure legend:Figure S6 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:foGxFzU5iERAVn5j9tPFh9T4Oio9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:39AEBBC7E54F350C|rigid:PGvhO/N/jUZd3bxPXbPm+FeY95I false myc tag:n-n flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9NPI6 uniprotkb:Q9NPI6 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Fenger-Gron et al. (2005) pubmed:16364915 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1162658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:S1 taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/08/23 2018/09/18 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 intact-crc:F331FEB22256C670|rigid:0kyBSmwkzow69vuNokDtToqBwKQ false - flag tag:n-n - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)