#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25374	uniprotkb:Q6Q560	intact:EBI-11991|ensemblfungi:YCL017C|uniprotkb:D6VQZ7	intact:EBI-784315|uniprotkb:D3DLV0|ensemblfungi:YER048W-A	psi-mi:nfs1_yeast(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:SPL1(gene name synonym)|uniprotkb:YCL017C(locus name)|uniprotkb:tRNA-splicing protein SPL1(gene name synonym)	psi-mi:isd11_yeast(display_long)|uniprotkb:Iron-sulfur protein biogenesis, desulfurase-interacting protein 11(gene name synonym)|uniprotkb:YER048W-A(locus name)|uniprotkb:ISD11(gene name)|psi-mi:ISD11(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Wiedemann et al. (2006)	pubmed:16341089|imex:IM-11435|mint:MINT-5218092	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7933776|mint:MINT-2736200|imex:IM-11435-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCL017C(gene)|ensemblfungi:YCL017C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070903"(mitochondrial tRNA thio-modification)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|reactome:R-SCE-1362409|reactome:R-SCE-947581|go:"GO:1990221"(L-cysteine desulfurase complex)|refseq:NP_009912.2|sgd:S000000522|mint:P25374|dip:DIP-2948N|mint:MINT-2736202(identity)	interpro:IPR008011(Complex 1 LYR protein)|mint:Q6Q560|refseq:NP_010968.1|sgd:S000007237|ensemblfungi:YER048W-A(gene)|ensemblfungi:YER048W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:1990221"(L-cysteine desulfurase complex)|reactome:R-SCE-1362409|mint:MINT-2736201(identity)	-	crc64:D709E326B3921BCC|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/03	2014/10/16	rogid:Hko+QCpE9h22e3m1UVFDUSwpSSw559292	rogid:86dEspG26kfzQYYT7cr15DPRZvg559292	intact-crc:40BA1358895C0049|rigid:bbmu12F5Qx/rmmza6gH6j1f269s	false	-	calmodulin binding peptide plus protein a tag:?-?(MINT-2736213)	1	1	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6Q560	uniprotkb:P25374	intact:EBI-784315|uniprotkb:D3DLV0|ensemblfungi:YER048W-A	intact:EBI-11991|ensemblfungi:YCL017C|uniprotkb:D6VQZ7	psi-mi:isd11_yeast(display_long)|uniprotkb:Iron-sulfur protein biogenesis, desulfurase-interacting protein 11(gene name synonym)|uniprotkb:YER048W-A(locus name)|uniprotkb:ISD11(gene name)|psi-mi:ISD11(display_short)	psi-mi:nfs1_yeast(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:SPL1(gene name synonym)|uniprotkb:YCL017C(locus name)|uniprotkb:tRNA-splicing protein SPL1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Wiedemann et al. (2006)	pubmed:16341089|imex:IM-11435|mint:MINT-5218092	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7933803|mint:MINT-2736221|imex:IM-11435-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008011(Complex 1 LYR protein)|mint:Q6Q560|refseq:NP_010968.1|sgd:S000007237|ensemblfungi:YER048W-A(gene)|ensemblfungi:YER048W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:1990221"(L-cysteine desulfurase complex)|reactome:R-SCE-1362409|mint:MINT-2736222(identity)	ensemblfungi:YCL017C(gene)|ensemblfungi:YCL017C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070903"(mitochondrial tRNA thio-modification)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|reactome:R-SCE-1362409|reactome:R-SCE-947581|go:"GO:1990221"(L-cysteine desulfurase complex)|refseq:NP_009912.2|sgd:S000000522|mint:P25374|dip:DIP-2948N|mint:MINT-2736230(identity)	-	comment:"Stoichiometry: 1.0"	crc64:D709E326B3921BCC|comment:"Stoichiometry: 1.0"	figure legend:F6G|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/03	2014/10/16	rogid:86dEspG26kfzQYYT7cr15DPRZvg559292	rogid:Hko+QCpE9h22e3m1UVFDUSwpSSw559292	intact-crc:7BC03DFB5DA2BAF9|rigid:bbmu12F5Qx/rmmza6gH6j1f269s	false	-	tag:?-?(MINT-2736241)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25374	uniprotkb:Q03020	intact:EBI-11991|ensemblfungi:YCL017C|uniprotkb:D6VQZ7	intact:EBI-29901|uniprotkb:D6W3N2|ensemblfungi:YPL135W	psi-mi:nfs1_yeast(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:SPL1(gene name synonym)|uniprotkb:YCL017C(locus name)|uniprotkb:tRNA-splicing protein SPL1(gene name synonym)	psi-mi:isu1_yeast(display_long)|uniprotkb:YPL135W(locus name)|uniprotkb:Iron sulfur cluster scaffold protein 1(gene name synonym)|uniprotkb:ISU1(gene name)|psi-mi:ISU1(display_short)|uniprotkb:NUA1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Wiedemann et al. (2006)	pubmed:16341089|imex:IM-11435|mint:MINT-5218092	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7933820|mint:MINT-2736246|imex:IM-11435-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YCL017C(gene)|ensemblfungi:YCL017C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070903"(mitochondrial tRNA thio-modification)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|reactome:R-SCE-1362409|reactome:R-SCE-947581|go:"GO:1990221"(L-cysteine desulfurase complex)|refseq:NP_009912.2|sgd:S000000522|mint:P25374|dip:DIP-2948N|mint:MINT-2736253(identity)	refseq:NP_015190.1|sgd:S000006056|dip:DIP-6556N|mint:Q03020|ensemblfungi:YPL135W(gene)|ensemblfungi:YPL135W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1362409|mint:MINT-2736247(identity)	-	crc64:D709E326B3921BCC|comment:"Stoichiometry: 1.0"	crc64:E240845A27D2E9EE|comment:"Stoichiometry: 1.0"	figure legend:F6G|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/07/03	2014/10/16	rogid:Hko+QCpE9h22e3m1UVFDUSwpSSw559292	rogid:zpPseOgZoK3cF+mCetzw05ct9Kc559292	intact-crc:A7B17F692AA5F241|rigid:4eFCcUqVaXfoyLzfAYMIHROSmH8	false	tag:?-?(MINT-2736257)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6Q560	uniprotkb:P25374	intact:EBI-784315|uniprotkb:D3DLV0|ensemblfungi:YER048W-A	intact:EBI-11991|ensemblfungi:YCL017C|uniprotkb:D6VQZ7	psi-mi:isd11_yeast(display_long)|uniprotkb:Iron-sulfur protein biogenesis, desulfurase-interacting protein 11(gene name synonym)|uniprotkb:YER048W-A(locus name)|uniprotkb:ISD11(gene name)|psi-mi:ISD11(display_short)	psi-mi:nfs1_yeast(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:SPL1(gene name synonym)|uniprotkb:YCL017C(locus name)|uniprotkb:tRNA-splicing protein SPL1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Wiedemann et al. (2006)	pubmed:16341089|imex:IM-11435|mint:MINT-5218092	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7933847|mint:MINT-2736264|imex:IM-11435-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008011(Complex 1 LYR protein)|mint:Q6Q560|refseq:NP_010968.1|sgd:S000007237|ensemblfungi:YER048W-A(gene)|ensemblfungi:YER048W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:1990221"(L-cysteine desulfurase complex)|reactome:R-SCE-1362409|mint:MINT-2736265(identity)	ensemblfungi:YCL017C(gene)|ensemblfungi:YCL017C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070903"(mitochondrial tRNA thio-modification)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|reactome:R-SCE-1362409|reactome:R-SCE-947581|go:"GO:1990221"(L-cysteine desulfurase complex)|refseq:NP_009912.2|sgd:S000000522|mint:P25374|dip:DIP-2948N|mint:MINT-2736271(identity)	-	comment:"Stoichiometry: 1.0"	crc64:D709E326B3921BCC|comment:"Stoichiometry: 1.0"	figure legend:F6B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:86dEspG26kfzQYYT7cr15DPRZvg559292	rogid:Hko+QCpE9h22e3m1UVFDUSwpSSw559292	intact-crc:F88161578C9872FF|rigid:bbmu12F5Qx/rmmza6gH6j1f269s	false	-	tag:?-?(MINT-2736274)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6Q560	uniprotkb:P25374	intact:EBI-784315|uniprotkb:D3DLV0|ensemblfungi:YER048W-A	intact:EBI-11991|ensemblfungi:YCL017C|uniprotkb:D6VQZ7	psi-mi:isd11_yeast(display_long)|uniprotkb:Iron-sulfur protein biogenesis, desulfurase-interacting protein 11(gene name synonym)|uniprotkb:YER048W-A(locus name)|uniprotkb:ISD11(gene name)|psi-mi:ISD11(display_short)	psi-mi:nfs1_yeast(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:SPL1(gene name synonym)|uniprotkb:YCL017C(locus name)|uniprotkb:tRNA-splicing protein SPL1(gene name synonym)	psi-mi:"MI:0276"(blue native page)	Wiedemann et al. (2006)	pubmed:16341089|imex:IM-11435|mint:MINT-5218092	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7933874|mint:MINT-2736314|imex:IM-11435-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR008011(Complex 1 LYR protein)|mint:Q6Q560|refseq:NP_010968.1|sgd:S000007237|ensemblfungi:YER048W-A(gene)|ensemblfungi:YER048W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:1990221"(L-cysteine desulfurase complex)|reactome:R-SCE-1362409|mint:MINT-2736315(identity)	ensemblfungi:YCL017C(gene)|ensemblfungi:YCL017C_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0034227"(tRNA thio-modification)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0070903"(mitochondrial tRNA thio-modification)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020578|reactome:R-SCE-1362409|reactome:R-SCE-947581|go:"GO:1990221"(L-cysteine desulfurase complex)|refseq:NP_009912.2|sgd:S000000522|mint:P25374|dip:DIP-2948N|mint:MINT-2736320(identity)	-	comment:"Stoichiometry: 1.0"	crc64:D709E326B3921BCC|comment:"Stoichiometry: 1.0"	figure legend:F6E|figure legend:F6D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/07/03	2014/10/16	rogid:86dEspG26kfzQYYT7cr15DPRZvg559292	rogid:Hko+QCpE9h22e3m1UVFDUSwpSSw559292	intact-crc:60BE980361ECD5F3|rigid:bbmu12F5Qx/rmmza6gH6j1f269s	false	-	tag:?-?(MINT-2736325)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)