#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P19490	uniprotkb:P70569	intact:EBI-371642	intact:EBI-975940	psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym)	psi-mi:myo5b_rat(display_long)|uniprotkb:Myosin heavy chain myr 6(gene name synonym)|uniprotkb:Myo5b(gene name)|psi-mi:Myo5b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-975955|imex:IM-14419-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N	go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905430"(cellular response to glycine)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098944"(postsynaptic recycling endosome membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|rgd:621347|refseq:NP_058779.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|interpro:IPR037990|interpro:IPR036103|reactome:R-RNO-432040	psi-mi:"MI:0469"(intact)	-	-	figure legend:2K, 5G, 5H|comment:Interaction was observed in both P17 stage and adult rat brain lysate.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2006/07/25	2014/10/16	rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116	rogid:aSy8jU0zb6HSOizEuIzKZCLdfVs10116	intact-crc:D6560415ACA987A8|rigid:3Kzep/qh9gY5aAvDnMkB72a2btY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P19490	uniprotkb:P70569	intact:EBI-371642	intact:EBI-975940	psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym)	psi-mi:myo5b_rat(display_long)|uniprotkb:Myosin heavy chain myr 6(gene name synonym)|uniprotkb:Myo5b(gene name)|psi-mi:Myo5b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976011|imex:IM-14419-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N	go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905430"(cellular response to glycine)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098944"(postsynaptic recycling endosome membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|rgd:621347|refseq:NP_058779.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|interpro:IPR037990|interpro:IPR036103|reactome:R-RNO-432040	psi-mi:"MI:0469"(intact)	-	-	figure legend:2L|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2006/07/25	2014/10/16	rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116	rogid:aSy8jU0zb6HSOizEuIzKZCLdfVs10116	intact-crc:A5C1BDF19954E47E|rigid:0wD57Q7sqOp8ZsXwdBm8ymPgn0o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P19490	uniprotkb:P19491	intact:EBI-371642	intact:EBI-77718|uniprotkb:Q9R174	psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym)	psi-mi:gria2_rat(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976011|imex:IM-14419-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N	go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|interpro:IPR028082|rcsb pdb:1FTJ|rcsb pdb:1FTK|rcsb pdb:1FTL|rcsb pdb:1FTM|rcsb pdb:1FTO|rcsb pdb:1FW0|rcsb pdb:1GR2|rcsb pdb:1LB8|rcsb pdb:1LB9|rcsb pdb:1LBB|rcsb pdb:1LBC|rcsb pdb:1M5B|rcsb pdb:1M5C|rcsb pdb:1M5D|rcsb pdb:1M5E|rcsb pdb:1M5F|rcsb pdb:1MM6|rcsb pdb:1MM7|rcsb pdb:1MQD|rcsb pdb:1MQG|rcsb pdb:1MQH|rcsb pdb:1MQI|rcsb pdb:1MQJ|rcsb pdb:1MS7|rcsb pdb:1MXU|rcsb pdb:1MXV|rcsb pdb:1MXW|rcsb pdb:1MXX|rcsb pdb:1MXY|rcsb pdb:1MXZ|rcsb pdb:1MY0|rcsb pdb:1MY1|rcsb pdb:1MY2|rcsb pdb:1MY3|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|rcsb pdb:1MY4|rcsb pdb:1N0T|rcsb pdb:1NNK|rcsb pdb:1NNP|rcsb pdb:1P1N|rcsb pdb:1P1O|rcsb pdb:1P1Q|rcsb pdb:1P1U|rcsb pdb:1P1W|rcsb pdb:1SYH|rcsb pdb:1SYI|rcsb pdb:1WVJ|rcsb pdb:1XHY|rcsb pdb:2AIX|rcsb pdb:2AL4|rcsb pdb:2AL5|rcsb pdb:2ANJ|rcsb pdb:2CMO|rcsb pdb:2GFE|rcsb pdb:2I3V|rcsb pdb:2I3W|rcsb pdb:2P2A|rcsb pdb:2UXA|rcsb pdb:2XX7|rcsb pdb:2XX8|rcsb pdb:2XX9|rcsb pdb:2XXH|rcsb pdb:2XXI|rcsb pdb:3B6Q|rcsb pdb:5NIH|rcsb pdb:5NS9|rcsb pdb:5O9A|rcsb pdb:5OEW|rcsb pdb:5VHW|rcsb pdb:5VHX|rcsb pdb:5VHY|rcsb pdb:5VHZ|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|rcsb pdb:5WEO|rcsb pdb:6DLZ|rcsb pdb:6DM0|rcsb pdb:6DM1|rcsb pdb:6FAZ|rcsb pdb:6FQG|rcsb pdb:6FQH|rcsb pdb:6FQI|rcsb pdb:6FQJ|rcsb pdb:6FQK|rcsb pdb:6GIV|rcsb pdb:6GL4|rcsb pdb:6HC9|rcsb pdb:6HCA|rcsb pdb:6HCB|rcsb pdb:6HCC|rcsb pdb:6HCH|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6O9G|rcsb pdb:6PEQ|rcsb pdb:6Q54|rcsb pdb:6Q60|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:3B6T|rcsb pdb:3B6W|rcsb pdb:3B7D|rcsb pdb:3BBR|rcsb pdb:3BFT|rcsb pdb:3BFU|rcsb pdb:3BKI|rcsb pdb:3DP6|rcsb pdb:3H03|rcsb pdb:3H06|rcsb pdb:3H5V|rcsb pdb:3H5W|rcsb pdb:3H6T|rcsb pdb:3H6U|rcsb pdb:3H6V|rcsb pdb:3H6W|rcsb pdb:3HSY|rcsb pdb:3IJO|rcsb pdb:3IJX|rcsb pdb:3IK6|rcsb pdb:3IL1|rcsb pdb:3ILT|rcsb pdb:3ILU|rcsb pdb:3KG2|rcsb pdb:3KGC|rcsb pdb:3LSF|rcsb pdb:3LSL|rcsb pdb:3M3L|rcsb pdb:3N6V|rcsb pdb:3O28|rcsb pdb:3O29|rcsb pdb:3O2A|rcsb pdb:3O2J|rcsb pdb:3O6G|rcsb pdb:3O6H|rcsb pdb:3O6I|rcsb pdb:3PD8|rcsb pdb:3PD9|rcsb pdb:3PMV|rcsb pdb:3PMW|rcsb pdb:3PMX|rcsb pdb:6RUQ|rcsb pdb:6U5S|rcsb pdb:6U6I|rcsb pdb:6UCB|rcsb pdb:6UD4|rcsb pdb:6UD8|rcsb pdb:6XSR|rcsb pdb:6YK2|rcsb pdb:6YK3|rcsb pdb:6YK4|rcsb pdb:6YK5|rcsb pdb:6YK6|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-399710|reactome:R-RNO-416993|reactome:R-RNO-438066|rcsb pdb:3RTF|rcsb pdb:3RTW|rcsb pdb:3T93|rcsb pdb:3T96|rcsb pdb:3T9H|rcsb pdb:3T9U|rcsb pdb:3T9V|rcsb pdb:3T9X|rcsb pdb:3TDJ|rcsb pdb:3TKD|rcsb pdb:3TZA|rcsb pdb:4FAT|rcsb pdb:4G8M|rcsb pdb:4GXS|rcsb pdb:4H8J|rcsb pdb:4IGT|rcsb pdb:4ISU|rcsb pdb:4IY5|rcsb pdb:4IY6|rcsb pdb:4L17|rcsb pdb:4LZ5|rcsb pdb:4LZ7|rcsb pdb:4LZ8|rcsb pdb:4N07|rcsb pdb:4O3A|rcsb pdb:4O3B|rcsb pdb:4O3C|rcsb pdb:4Q30|rcsb pdb:4U1O|rcsb pdb:4U1W|rcsb pdb:4U1X|rcsb pdb:4U1Y|rcsb pdb:4U1Z|rcsb pdb:4U21|rcsb pdb:4U22|rcsb pdb:4U23|rcsb pdb:4U2P|rcsb pdb:4U2Q|rcsb pdb:4U2R|rcsb pdb:4U4F|rcsb pdb:4U4G|rcsb pdb:4U4S|rcsb pdb:4U4X|rcsb pdb:4U5B|rcsb pdb:4U5C|rcsb pdb:4U5D|rcsb pdb:4U5E|rcsb pdb:4U5F|rcsb pdb:4UQ6|rcsb pdb:4UQJ|rcsb pdb:4UQK|rcsb pdb:4X48|rcsb pdb:4YMA|rcsb pdb:4YU0|rcsb pdb:4Z0I|rcsb pdb:5BUU|rcsb pdb:5CBR|rcsb pdb:5CBS|rcsb pdb:5ELV|rcsb pdb:5FHM|rcsb pdb:5FHN|rcsb pdb:5FHO|rcsb pdb:5FTH|rcsb pdb:5FTI|rcsb pdb:5FWX|rcsb pdb:5FWY|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:5JEI|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5KBV|rcsb pdb:5KK2|rcsb pdb:5L1B|rcsb pdb:5L1E|rcsb pdb:5L1F|rcsb pdb:5L1G|rcsb pdb:5L1H|rcsb pdb:5N6P|rcsb pdb:5NG9|refseq:NP_001077280.1|refseq:NP_058957.1|rgd:61862|mint:P19491|dip:DIP-30952N	psi-mi:"MI:0469"(intact)	-	-	figure legend:2L|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2006/07/25	2014/10/16	rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116	rogid:zeQRRvspsIuRyA9kKA7kyIr8HqE10116	intact-crc:A5C1BDF19954E47E|rigid:0wD57Q7sqOp8ZsXwdBm8ymPgn0o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O70277	uniprotkb:P70569	intact:EBI-976045	intact:EBI-975940	psi-mi:trim3_rat(display_long)|uniprotkb:RING finger protein 22(gene name synonym)|uniprotkb:Brain-expressed RING finger protein(gene name synonym)|uniprotkb:Trim3(gene name)|psi-mi:Trim3(display_short)|uniprotkb:Berp(gene name synonym)|uniprotkb:Rnf22(gene name synonym)	psi-mi:myo5b_rat(display_long)|uniprotkb:Myosin heavy chain myr 6(gene name synonym)|uniprotkb:Myo5b(gene name)|psi-mi:Myo5b(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976061|imex:IM-14419-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|rgd:70074|refseq:NP_113974.1|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370	go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905430"(cellular response to glycine)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098944"(postsynaptic recycling endosome membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|rgd:621347|refseq:NP_058779.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|interpro:IPR037990|interpro:IPR036103|reactome:R-RNO-432040	psi-mi:"MI:0469"(intact)	-	-	figure legend:S4|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/07/25	2014/10/16	rogid:6SW7y822TACGfv/Zt0hQrFiyF/810116	rogid:aSy8jU0zb6HSOizEuIzKZCLdfVs10116	intact-crc:C738E60E82457FB8|rigid:Slt67QUxzIUZIjKNN64XoEbsy0k	false	flag tag:?-?	green fluorescent protein tag:?-?|sufficient binding region:1221-1846	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07825	uniprotkb:P70569	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-975940	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:myo5b_rat(display_long)|uniprotkb:Myosin heavy chain myr 6(gene name synonym)|uniprotkb:Myo5b(gene name)|psi-mi:Myo5b(display_short)	psi-mi:"MI:0428"(imaging technique)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976097|imex:IM-14419-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905430"(cellular response to glycine)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098944"(postsynaptic recycling endosome membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|rgd:621347|refseq:NP_058779.1|interpro:IPR002710(Dilute)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036961|interpro:IPR037990|interpro:IPR036103|reactome:R-RNO-432040	go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0043197"(dendritic spine)	-	-	figure legend:S1|comment:Colocalisation o bserved in DIV 28 neurons but not in Div 7 neurons.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell)	-	2006/07/25	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:aSy8jU0zb6HSOizEuIzKZCLdfVs10116	intact-crc:93E3D6BD23F0E938|rigid:VEWaYzigziaMwpV5C2SpbDOlJw8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19490	uniprotkb:P07825	intact:EBI-371642	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0428"(imaging technique)	Lise et al. (2006)	imex:IM-14419|pubmed:16338934	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-976104|imex:IM-14419-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0043197"(dendritic spine)	-	-	figure legend:S1|comment:Colocalisation o bserved in DIV 28 neurons but not in Div 7 neurons.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell)	-	2006/07/25	2014/10/16	rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	intact-crc:56309D4160F3612F|rigid:i7+7MaRLl7jdz7O7fk67cfXp+sE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)