#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q93034	uniprotkb:Q96Q27-2	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	intact:EBI-28950233	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:q96q27-2(display_long)|uniprotkb:ASB2(gene name)|psi-mi:ASB2(display_short)|uniprotkb:ASB2beta(isoform synonym)|uniprotkb:muscle-type(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911744|mint:MINT-75029|imex:IM-11065-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500428(identity)	intact:EBI-2880677(isoform-parent)|mint:MINT-1500419(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2021/12/08	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	rogid:ro7HeeKhV1dq5Lmm6WPU0eUrGK89606	intact-crc:AB63A92B6EDEA69C|rigid:YQ+CXM9w28L4Zey4EYNSE7Tqpk4	false	-	necessary binding region:587-635(IPR001496)|flag tag:?-?(MINT-1500422)	1	1	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96Q27-2	uniprotkb:Q93034	intact:EBI-28950233	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	psi-mi:q96q27-2(display_long)|uniprotkb:ASB2(gene name)|psi-mi:ASB2(display_short)|uniprotkb:ASB2beta(isoform synonym)|uniprotkb:muscle-type(isoform synonym)	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911798|mint:MINT-77968|imex:IM-11065-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2880677(isoform-parent)|mint:MINT-1500507(identity)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500520(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2021/12/08	rogid:ro7HeeKhV1dq5Lmm6WPU0eUrGK89606	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	intact-crc:DCD4F160750F36AD|rigid:YQ+CXM9w28L4Zey4EYNSE7Tqpk4	false	flag tag:?-?(MINT-1500514)|binding-associated region:593-632(MINT-1500508)|mutation disrupting interaction strength:619-622|mutation disrupting interaction strength:599-600	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96Q27-2	uniprotkb:Q9UBF6	intact:EBI-28950233	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	psi-mi:q96q27-2(display_long)|uniprotkb:ASB2(gene name)|psi-mi:ASB2(display_short)|uniprotkb:ASB2beta(isoform synonym)|uniprotkb:muscle-type(isoform synonym)	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911844|mint:MINT-77969|imex:IM-11065-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2880677(isoform-parent)|mint:MINT-1500437(identity)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|mint:MINT-1500450(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2021/12/08	rogid:ro7HeeKhV1dq5Lmm6WPU0eUrGK89606	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	intact-crc:EA71DDC8578D0762|rigid:/G/dPZfI4tj35MeIKIi9/k11fZg	false	flag tag:?-?(MINT-1500444)|binding-associated region:593-632(MINT-1500438)|mutation disrupting interaction:619-622(MINT-1500441)|mutation disrupting interaction strength:599-600	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y576	uniprotkb:Q93034	intact:EBI-2323092|uniprotkb:A6NL50|uniprotkb:Q4ZG29|uniprotkb:Q9ULS4|ensembl:ENSP00000264607	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	psi-mi:asb1_human(display_long)|uniprotkb:ASB1(gene name)|psi-mi:ASB1(display_short)|uniprotkb:KIAA1146(gene name synonym)	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911872|mint:MINT-77970|imex:IM-11065-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035535.1|ensembl:ENSG00000065802(gene)|ensembl:ENST00000264607(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030539"(male genitalia development)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037331|reactome:R-HSA-8951664|reactome:R-HSA-983168|mint:MINT-1500322(identity)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500329(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:AFugylzpLygbsabXTyNfcL718xY9606	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	intact-crc:FFAAEEC5BA969190|rigid:dXbF/K4wqSPX3ADa5ji2UP5PBO0	false	flag tag:?-?(MINT-1500323)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y576	uniprotkb:Q9UBF6	intact:EBI-2323092|uniprotkb:A6NL50|uniprotkb:Q4ZG29|uniprotkb:Q9ULS4|ensembl:ENSP00000264607	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	psi-mi:asb1_human(display_long)|uniprotkb:ASB1(gene name)|psi-mi:ASB1(display_short)|uniprotkb:KIAA1146(gene name synonym)	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911952|mint:MINT-77973|imex:IM-11065-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035535.1|ensembl:ENSG00000065802(gene)|ensembl:ENST00000264607(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030539"(male genitalia development)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037331|reactome:R-HSA-8951664|reactome:R-HSA-983168|mint:MINT-1500491(identity)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|mint:MINT-1500498(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:AFugylzpLygbsabXTyNfcL718xY9606	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	intact-crc:82C65D84DD13D9F8|rigid:XKTEl1vE0IBQBn3jaOMqP6D+iUY	false	flag tag:?-?(MINT-1500492)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NWX5	uniprotkb:Q93034	intact:EBI-6425205|ensembl:ENSP00000277458|uniprotkb:Q9BV15|uniprotkb:Q5SZB7	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	psi-mi:asb6_human(display_long)|uniprotkb:ASB6(gene name)|psi-mi:ASB6(display_short)	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911935|mint:MINT-77972|imex:IM-11065-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000148331(gene)|ensembl:ENST00000277458(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037327|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001189332.1|refseq:NP_060343.1|refseq:NP_821066.1|mint:MINT-1500290(identity)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500297(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:rY7CErPA4Y+wLyfVov0JP8YS9lA9606	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	intact-crc:38DEE4D0EDE4FE6D|rigid:WSCJe0PoUmfZoEnz1ogBbYiR2LQ	false	flag tag:?-?(MINT-1500291)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NWX5	uniprotkb:Q9UBF6	intact:EBI-6425205|ensembl:ENSP00000277458|uniprotkb:Q9BV15|uniprotkb:Q5SZB7	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	psi-mi:asb6_human(display_long)|uniprotkb:ASB6(gene name)|psi-mi:ASB6(display_short)	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911919|mint:MINT-77971|imex:IM-11065-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000148331(gene)|ensembl:ENST00000277458(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037327|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001189332.1|refseq:NP_060343.1|refseq:NP_821066.1|mint:MINT-1500338(identity)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|mint:MINT-1500345(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:rY7CErPA4Y+wLyfVov0JP8YS9lA9606	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	intact-crc:D04230F4218EC0B3|rigid:gIi7jGQJDq34eg1XlL2wNUfDLsA	false	flag tag:?-?(MINT-1500339)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WXK4	uniprotkb:Q93034	intact:EBI-7911975|intact:MINT-1500389|uniprotkb:Q52LK4|uniprotkb:J3KP57|uniprotkb:Q2M3D5|uniprotkb:Q8N8F5|uniprotkb:Q6ISF9	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	psi-mi:asb12_human(display_long)|uniprotkb:ASB12(gene name)|psi-mi:ASB12(display_short)	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7912024|mint:MINT-77976|imex:IM-11065-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR020683|refseq:NP_569059.3|reactome:R-HSA-983168|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-8951664|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR036770|mint:MINT-1500403(identity)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500410(identity)	-	function:"Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:VVzSyw5LFKkGA9NsTtkbgf+7+jQ9606	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	intact-crc:C9123CE4227A942F|rigid:Eg0fV6L/Hpoil5e3eeJDui3rlVw	false	flag tag:?-?(MINT-1500404)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WXK4	uniprotkb:Q9UBF6	intact:EBI-7911975|intact:MINT-1500389|uniprotkb:Q52LK4|uniprotkb:J3KP57|uniprotkb:Q2M3D5|uniprotkb:Q8N8F5|uniprotkb:Q6ISF9	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	psi-mi:asb12_human(display_long)|uniprotkb:ASB12(gene name)|psi-mi:ASB12(display_short)	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7911968|mint:MINT-77975|imex:IM-11065-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR020683|refseq:NP_569059.3|reactome:R-HSA-983168|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|reactome:R-HSA-8951664|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR036770|mint:MINT-1500475(identity)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|mint:MINT-1500482(identity)	-	function:"Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins"|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:VVzSyw5LFKkGA9NsTtkbgf+7+jQ9606	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	intact-crc:234F9D69287B1A8C|rigid:tAt+QyLLbRtrIQzMVRKRcykE5gA	false	flag tag:?-?(MINT-1500476)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H672	uniprotkb:Q93034	intact:EBI-3916346|uniprotkb:Q7Z4S3|uniprotkb:A8K1E5|uniprotkb:Q6GSJ6|ensembl:ENSP00000328327	intact:EBI-1057139|uniprotkb:O14766|uniprotkb:Q9BZC6|uniprotkb:A8K960|ensembl:ENSP00000376808|ensembl:ENSP00000435376	psi-mi:asb7_human(display_long)|uniprotkb:ASB7(gene name)|psi-mi:ASB7(display_short)	psi-mi:cul5_human(display_long)|uniprotkb:CUL5(gene name)|psi-mi:CUL5(display_short)|uniprotkb:VACM1(gene name synonym)|uniprotkb:Vasopressin-activated calcium-mobilizing receptor 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7912041|mint:MINT-77977|imex:IM-11065-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078984.2|refseq:NP_937886.1|ensembl:ENSG00000183475(gene)|ensembl:ENST00000332783(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037326|reactome:R-HSA-8951664|reactome:R-HSA-983168|dip:DIP-43701N|mint:MINT-1500373(identity)	refseq:NP_003469.2|ensembl:ENSG00000166266(gene)|ensembl:ENST00000393094(transcript)|ensembl:ENST00000531427(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q93034|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:4JGH|rcsb pdb:4N9F|rcsb pdb:6V9I|reactome:R-HSA-180585|reactome:R-HSA-8863795|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|dip:DIP-43696N|mint:MINT-1500380(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:oi6qH/JLzTvIaKcFQ+9XWnWkpTo9606	rogid:rmqOrKvxsALWuSvEcrPXxtNrcpc9606	intact-crc:C6548474CCBCF3C0|rigid:SoB0W0L/AhyYik2VKiTzEhMUDbw	false	flag tag:?-?(MINT-1500374)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H672	uniprotkb:Q9UBF6	intact:EBI-3916346|uniprotkb:Q7Z4S3|uniprotkb:A8K1E5|uniprotkb:Q6GSJ6|ensembl:ENSP00000328327	intact:EBI-398632|uniprotkb:Q9BXN8|uniprotkb:Q9Y5M7|uniprotkb:A8MTB5|uniprotkb:A8K1H9|uniprotkb:D3DNF7|uniprotkb:D3DNF8|uniprotkb:C9JYL3|ensembl:ENSP00000273480	psi-mi:asb7_human(display_long)|uniprotkb:ASB7(gene name)|psi-mi:ASB7(display_short)	psi-mi:rbx2_human(display_long)|uniprotkb:RNF7(gene name)|psi-mi:RNF7(display_short)|uniprotkb:RBX2(gene name synonym)|uniprotkb:ROC2(gene name synonym)|uniprotkb:SAG(gene name synonym)|uniprotkb:RING finger protein 7(gene name synonym)|uniprotkb:Regulator of cullins 2(gene name synonym)|uniprotkb:CKII beta-binding protein 1(gene name synonym)|uniprotkb:Sensitive to apoptosis gene protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kohroki et al. (2005)	pubmed:16325183|imex:IM-11065|mint:MINT-5218083	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7912058|mint:MINT-77978|imex:IM-11065-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078984.2|refseq:NP_937886.1|ensembl:ENSG00000183475(gene)|ensembl:ENST00000332783(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037326|reactome:R-HSA-8951664|reactome:R-HSA-983168|dip:DIP-43701N|mint:MINT-1500459(identity)	refseq:NP_055060.1|refseq:NP_899060.1|refseq:NP_001188299.1|ensembl:ENSG00000114125(gene)|ensembl:ENST00000273480(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0045116"(protein neddylation)|go:"GO:0051775"(response to redox state)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|rcsb pdb:2ECL|reactome:R-HSA-8951664|reactome:R-HSA-9705462|reactome:R-HSA-983168|mint:MINT-1500466(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/01/27	2014/10/16	rogid:oi6qH/JLzTvIaKcFQ+9XWnWkpTo9606	rogid:FNop0ozErv05khKc5si7nNH/Hww9606	intact-crc:16A07A65538BE4E0|rigid:s5eUkFZPQECq1opcNvopLkbqj70	false	flag tag:?-?(MINT-1500460)	-	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)