#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17096-1	uniprotkb:Q96LA8	intact:EBI-746854|ensembl:ENSP00000308227|ensembl:ENSP00000399888|intact:EBI-8455830|intact:MINT-262970	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:p17096-1(display_long)|uniprotkb:HMGA1a(isoform synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912449|imex:IM-14484-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746843(hmgiy_human)|ensembl:ENSG00000137309(gene)|ensembl:ENST00000311487(transcript)|ensembl:ENST00000447654(transcript)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/03/28	2014/10/16	rogid:hhCMZ6CUf3e+PD0RNIauCZ8EThM9606	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:EAACC31F101BEFBD|rigid:dJpTc/aBY5MUGVYXHjVbHw75Ieo	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17096-1	uniprotkb:Q96LA8	intact:EBI-746854|ensembl:ENSP00000308227|ensembl:ENSP00000399888|intact:EBI-8455830|intact:MINT-262970	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:p17096-1(display_long)|uniprotkb:HMGA1a(isoform synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912467|imex:IM-14484-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-746843(hmgiy_human)|ensembl:ENSG00000137309(gene)|ensembl:ENST00000311487(transcript)|ensembl:ENST00000447654(transcript)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:Hek293 Cell lysates and various deletion mutants were used to obtain the results.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2014/10/16	rogid:hhCMZ6CUf3e+PD0RNIauCZ8EThM9606	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:919A1C28EFE67F26|rigid:dJpTc/aBY5MUGVYXHjVbHw75Ieo	false	sufficient binding region:53-77	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96LA8	uniprotkb:P17096-2	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-746858|ensembl:ENSP00000288245|ensembl:ENSP00000363230|ensembl:ENSP00000385693	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:p17096-2(display_long)|uniprotkb:HMGA1b(isoform synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912487|imex:IM-14484-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	intact:EBI-746843(hmgiy_human)|ensembl:ENSG00000137309(gene)|ensembl:ENST00000347617(transcript)|ensembl:ENST00000374116(transcript)|ensembl:ENST00000401473(transcript)|uniprotkb:P17096-2(isoform-parent)	go:"GO:0016273"(arginine N-methyltransferase activity)	-	isoform-comment:Contains a phosphothreonine at position 67. Contains a phosphothreonine at position 42.	comment:HEK 293 lysates were used for WT HMGA1b interaction|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2014/10/16	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:QL8/APvYERa2EQdmzd5srAdhpkk9606	intact-crc:FD02A35F7D18F83A|rigid:vTyrFTtyqD9blj6k+Af+KR5n7Fc	false	ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P52926	uniprotkb:Q96LA8	intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912523|imex:IM-14484-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	psi-mi:"MI:0469"(intact)	-	-	comment:HEK 293 lysates were used for WT HMGA2 interaction|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2014/10/16	rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:7A1A9D73B33D8C3F|rigid:v5+gJpE3gvb9dJBjZT5kjaG9um4	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99873	uniprotkb:P52926	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912570|imex:IM-14484-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction performed in the presence of H3 labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2018/04/06	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606	intact-crc:2D13E1239736AB7C	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q99873	intact:EBI-980183	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912570|imex:IM-14484-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction performed in the presence of H3 labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2018/04/06	-	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	intact-crc:2D13E1239736AB7C	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99873	uniprotkb:P52927	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912591|imex:IM-14484-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction performed in the presence of H3 labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2018/04/06	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090	intact-crc:2D5DA498697310CC	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q99873	intact:EBI-980183	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912591|imex:IM-14484-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction performed in the presence of H3 labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2018/04/06	-	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	intact-crc:2D5DA498697310CC	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P17095-2	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-912617|ensembl:ENSMUSP00000100667|ensembl:ENSMUSP00000113015|ensembl:ENSMUSP00000113916|ensembl:ENSMUSP00000155886|ensembl:ENSMUSP00000156173|ensembl:ENSMUSP00000156199	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:p17095-2(display_long)|uniprotkb:HMGA1a(isoform synonym)|uniprotkb:Hmga1(gene name)|psi-mi:Hmga1(display_short)|uniprotkb:Hmgi(gene name synonym)|uniprotkb:Hmgiy(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912628|imex:IM-14484-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	intact:EBI-912604(hmgiy_mouse)|ensembl:ENSMUSG00000046711(gene)|ensembl:ENSMUSG00000078249(gene)|ensembl:ENSMUST00000105046(transcript)|ensembl:ENSMUST00000118599(transcript)|ensembl:ENSMUST00000119486(transcript)|ensembl:ENSMUST00000231874(transcript)|ensembl:ENSMUST00000232013(transcript)|ensembl:ENSMUST00000232265(transcript)	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:8GAWIHsX1UJjnQrxhZp9UTPLBTI10090	intact-crc:14CB5544F610316A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912628|imex:IM-14484-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:14CB5544F610316A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P17095-1	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-912622|ensembl:ENSMUSP00000110538|ensembl:ENSMUSP00000114101|ensembl:ENSMUSP00000155876|ensembl:ENSMUSP00000156044|ensembl:ENSMUSP00000156327	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:p17095-1(display_long)|uniprotkb:HMGA1b(isoform synonym)|uniprotkb:HMGI-E(isoform synonym)|uniprotkb:Hmga1(gene name)|psi-mi:Hmga1(display_short)|uniprotkb:Hmgi(gene name synonym)|uniprotkb:Hmgiy(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912634|imex:IM-14484-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	intact:EBI-912604(hmgiy_mouse)|ensembl:ENSMUSG00000046711(gene)|ensembl:ENSMUST00000114888(transcript)|ensembl:ENSMUST00000118570(transcript)|ensembl:ENSMUST00000231358(transcript)|ensembl:ENSMUST00000231825(transcript)|ensembl:ENSMUST00000232552(transcript)	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:o6hDXav9Q3uK3n/xZABgdrMeYHg10090	intact-crc:AB24559638DC33A4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912634|imex:IM-14484-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:AB24559638DC33A4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P17096-1	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-746854|ensembl:ENSP00000308227|ensembl:ENSP00000399888|intact:EBI-8455830|intact:MINT-262970	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:p17096-1(display_long)|uniprotkb:HMGA1a(isoform synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912640|imex:IM-14484-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	intact:EBI-746843(hmgiy_human)|ensembl:ENSG00000137309(gene)|ensembl:ENST00000311487(transcript)|ensembl:ENST00000447654(transcript)	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:hhCMZ6CUf3e+PD0RNIauCZ8EThM9606	intact-crc:7B81C2A35D61479A	false	-	mutation decreasing interaction:60-60,58-58|sufficient binding region:53-77	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912640|imex:IM-14484-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:7B81C2A35D61479A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P52926	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912646|imex:IM-14484-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606	intact-crc:EE73C4D1594994E9	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912646|imex:IM-14484-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:EE73C4D1594994E9	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P52927	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-912574|uniprotkb:Q3UQW0|ensembl:ENSMUSP00000072556	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:hmga2_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:Hmga2(gene name)|psi-mi:Hmga2(display_short)|uniprotkb:Hmgic(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912652|imex:IM-14484-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	refseq:NP_034571.1|refseq:NP_001334099.1|ensembl:ENSMUSG00000056758(gene)|ensembl:ENSMUST00000072777(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090276"(regulation of peptide hormone secretion)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR017956|mint:P52927|go:"GO:0006284"(base-excision repair)|reactome:R-MMU-2559584	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:xRfypuYHFPMesVHBe+5JD5TqFyQ10090	intact-crc:CCC34B1630384F97	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0516"(methyltransferase radiometric assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912652|imex:IM-14484-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:CCC34B1630384F97	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96LA8	uniprotkb:P17096-1	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	intact:EBI-746854|ensembl:ENSP00000308227|ensembl:ENSP00000399888|intact:EBI-8455830|intact:MINT-262970	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:p17096-1(display_long)|uniprotkb:HMGA1a(isoform synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912750|imex:IM-14484-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	intact:EBI-746843(hmgiy_human)|ensembl:ENSG00000137309(gene)|ensembl:ENST00000311487(transcript)|ensembl:ENST00000447654(transcript)	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|resulting-ptm:Time course of methyltransferase activity indicates the presence of monomethylarginines within 4 hours and dimethylarginine over 32 hours. Mehtylation occurs on R57 and R59 of HMGI/Y.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	rogid:hhCMZ6CUf3e+PD0RNIauCZ8EThM9606	intact-crc:34ECB03438BDE96D	false	-	sufficient binding region:57-63	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
chebi:"CHEBI:15414"	uniprotkb:Q96LA8	intact:EBI-980183	intact:EBI-912440|uniprotkb:Q5T5Y5|uniprotkb:Q6DKI4|uniprotkb:Q9NVR8|uniprotkb:A3KME1|uniprotkb:B4DID8|ensembl:ENSP00000359095	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:anm6_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6(gene name synonym)|uniprotkb:PRMT6(gene name)|psi-mi:PRMT6(display_short)|uniprotkb:HRMT1L6(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT6(gene name synonym)	psi-mi:"MI:0515"(methyltransferase assay)	Sgarra et al. (2006)	imex:IM-14484|pubmed:16293633	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-912750|imex:IM-14484-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_060607.2|ensembl:ENSG00000198890(gene)|ensembl:ENST00000370078(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0070611"("histone methyltransferase activity (H3-R2 specific)")|go:"GO:0070612"("histone methyltransferase activity (H2A-R3 specific)")|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q96LA8|rcsb pdb:4HC4|rcsb pdb:4QPP|rcsb pdb:4QQK|rcsb pdb:4Y2H|rcsb pdb:4Y30|rcsb pdb:5E8R|rcsb pdb:5EGS|rcsb pdb:5HZM|rcsb pdb:5WCF|rcsb pdb:6P7I|rcsb pdb:6W6D|rcsb pdb:6WAD|rcsb pdb:7NR4|reactome:R-HSA-3214858|reactome:R-HSA-8936459	go:"GO:0016273"(arginine N-methyltransferase activity)	-	-	comment:"Interaction carried out in the presence of H3 Labelled SAM CHEBI:15414"|resulting-ptm:Time course of methyltransferase activity indicates the presence of monomethylarginines within 4 hours and dimethylarginine over 32 hours. Mehtylation occurs on R57 and R59 of HMGI/Y.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/28	2015/08/18	-	rogid:0c6pV8lui9y+iXrlrOvxWjEZMf49606	intact-crc:34ECB03438BDE96D	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)