#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-987754	uniprotkb:Q9ZFS5	-	intact:EBI-986955|ensemblbacteria:CXO06415|ensemblbacteria:SPZ97046	psi-mi:q569j1_human(display_short)|psi-mi:EBI-987754(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)	psi-mi:q9zfs5_staau(display_long)|uniprotkb:set1(gene name)|psi-mi:set1(display_short)|uniprotkb:NCTC7878_00468(orf name)|uniprotkb:FPP26_02075(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Wines et al. (2006)	imex:IM-14492|pubmed:16293625	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-985594|imex:IM-14492-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q569J1(uniprot-removed-ac)	ensemblbacteria:CXO06415(transcript)|ensemblbacteria:ERS072840_02173(gene)|ensemblbacteria:NCTC7878_00468(gene)|ensemblbacteria:SPZ97046(transcript)|go:"GO:0005576"(extracellular region)|refseq:WP_000769829.1|rcsb pdb:1V1O|rcsb pdb:1V1P|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)	psi-mi:"MI:0469"(intact)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:1|kinetics:KD 6.8 plus or minus 0.8 E-9 M|comment:"The igha1 protein was fused to the human transferrin receptor (TfR)."|comment:The TfR-IgA Fc fusion protein was expressed in insect cells as a baculovirus expression vector was used.|caution:For the IgA1 Fc sequence the authors state there are two differences in sequence and have mapped L271M against the sequence corresponding to NG_001019 and R392H against the sequence corresponding to BC092449, which is a longer sequence.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/08	2014/10/16	rogid:+FgZJ0IBBJfh2rdkPSTOwC+qjBI9606	rogid:wRzROcZsmUWT87giekpGNq1HpJs1280	intact-crc:F167C0D11E5C3019|rigid:k+8W6TT8qI8zjheoGMb6dOQxnCU	false	fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-987754	uniprotkb:Q9ZFS5	-	intact:EBI-986955|ensemblbacteria:CXO06415|ensemblbacteria:SPZ97046	psi-mi:q569j1_human(display_short)|psi-mi:EBI-987754(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)	psi-mi:q9zfs5_staau(display_long)|uniprotkb:set1(gene name)|psi-mi:set1(display_short)|uniprotkb:NCTC7878_00468(orf name)|uniprotkb:FPP26_02075(orf name)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Wines et al. (2006)	imex:IM-14492|pubmed:16293625	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-987052|imex:IM-14492-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:Q569J1(uniprot-removed-ac)	ensemblbacteria:CXO06415(transcript)|ensemblbacteria:ERS072840_02173(gene)|ensemblbacteria:NCTC7878_00468(gene)|ensemblbacteria:SPZ97046(transcript)|go:"GO:0005576"(extracellular region)|refseq:WP_000769829.1|rcsb pdb:1V1O|rcsb pdb:1V1P|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR008375(Staphylococcus aureus exotoxin)|interpro:IPR015282(Staphylococcal toxin DUF1954)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|interpro:IPR006123(Toxin, beta-grasp, Staphylococcal/Streptococcal)	psi-mi:"MI:0469"(intact)	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	-	figure legend:2 B and D, 4|comment:"The igha1 protein was fused to the human transferrin receptor (TfR)."|caution:For the IgA1 Fc sequence the authors state there are two differences in sequence and have mapped L271M against the sequence corresponding to NG_001019 and R392H against the sequence corresponding to BC092449, which is a longer sequence.|comment:The TfR-IgA Fc fusion protein was expressed in insect cells as a baculovirus expression vector was used.|comment:"The Fc region of the human IgA1 derived from Dakiki cells was fused to the N-terminal region of the transferrin receptor which is a type II integral membrane protein. This fusion protein was expressed on the surface of CHOP cells (CHO cells expressing the early genes of the polyoma virus)."|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/08	2014/10/16	rogid:+FgZJ0IBBJfh2rdkPSTOwC+qjBI9606	rogid:wRzROcZsmUWT87giekpGNq1HpJs1280	intact-crc:D6F96786BDF30607|rigid:k+8W6TT8qI8zjheoGMb6dOQxnCU	false	mutation decreasing interaction:463-463|mutation decreasing interaction:278-278,279-279|mutation disrupting interaction:461-464|fusion protein:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8R3H6	intact:EBI-987754	intact:EBI-2659092	-	psi-mi:q8r3h6_mouse(display_long)|uniprotkb:Ighg(gene name)|psi-mi:Ighg(display_short)|uniprotkb:AU044919(gene name synonym)	psi-mi:q569j1_human(display_short)|psi-mi:EBI-987754(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Wines et al. (2006)	imex:IM-14492|pubmed:16293625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-987282|imex:IM-14492-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR036179	uniprotkb:Q569J1(uniprot-removed-ac)	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:|caution:The sequence has been withdrawn from uniprot.	figure legend:2 C and D, 4|caution:For the IgA1 Fc sequence the authors state there are two differences in sequence and have mapped L271M against the sequence corresponding to NG_001019 and R392H against the sequence corresponding to BC092449, which is a longer sequence.|comment:The TfR-IgA Fc fusion protein was expressed in insect cells as a baculovirus expression vector was used.|comment:"The Fc region of the human IgA1 derived from Dakiki cells was fused to the N-terminal region of the transferrin receptor which is a type II integral membrane protein. This fusion protein was expressed on the surface of CHOP cells (CHO cells expressing the early genes of the polyoma virus)."|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/08/08	2014/10/16	rogid:3KWJxgpJYUIrECqvZ89/wfNAKk810090	rogid:+FgZJ0IBBJfh2rdkPSTOwC+qjBI9606	intact-crc:32727DF9C16C2B29|rigid:E4uUPwviFYJjJJ+3W7V/Ph2Os9E	false	fusion protein:?-?|sufficient binding region:236-474	mutation disrupting interaction:463-463|mutation disrupting interaction:461-464|mutation decreasing interaction:278-278,279-279|mutation decreasing interaction:284-284|fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)