#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27682 uniprotkb:P28841 intact:EBI-988232 intact:EBI-988244|ensembl:ENSRNOP00000007249 psi-mi:7b2_rat(display_long)|uniprotkb:Secretory granule endocrine protein I(gene name synonym)|uniprotkb:Secretogranin-5(gene name synonym)|uniprotkb:Secretogranin V(gene name synonym)|uniprotkb:Scg5(gene name)|psi-mi:Scg5(display_short)|uniprotkb:Sgne1(gene name synonym) psi-mi:nec2_rat(display_long)|uniprotkb:Prohormone convertase 2(gene name synonym)|uniprotkb:Proprotein convertase 2(gene name synonym)|uniprotkb:KEX2-like endoprotease 2(gene name synonym)|uniprotkb:Pcsk2(gene name)|psi-mi:Pcsk2(display_short)|uniprotkb:Nec2(gene name synonym)|uniprotkb:Nec-2(gene name synonym)|uniprotkb:Rpc2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2006) imex:IM-14516|pubmed:16286464 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-988257|imex:IM-14516-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030141"(secretory granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0051082"(unfolded protein binding)|rgd:3669|refseq:NP_037307.1|interpro:IPR007945(Neuroendocrine 7B2 precursor) interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030070"(insulin processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0034230"(enkephalin processing)|go:"GO:0034231"(islet amyloid polypeptide processing)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|ensembl:ENSRNOG00000005438(gene)|ensembl:ENSRNOT00000007249(transcript)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|rgd:3273|refseq:NP_036878.1 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2A|comment:The authors concluded that non-phosphorylated 7B2 protein coimmunoprecipitated with PC2 protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rin_5f)|taxid:10116(Rattus norvegicus) - 2006/08/14 2014/10/16 rogid:eObAai+IWpXoSFmjZYvgbVhIV1010116 rogid:qUwGjsxB1A9uaDAAO8BczhkyoOY10116 intact-crc:8A3C3DDBCFDF728B|rigid:5iKXwom3iBLy5hr13X0atuxiMtg false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28841 uniprotkb:P27682 intact:EBI-988244|ensembl:ENSRNOP00000007249 intact:EBI-988232 psi-mi:nec2_rat(display_long)|uniprotkb:Prohormone convertase 2(gene name synonym)|uniprotkb:Proprotein convertase 2(gene name synonym)|uniprotkb:KEX2-like endoprotease 2(gene name synonym)|uniprotkb:Pcsk2(gene name)|psi-mi:Pcsk2(display_short)|uniprotkb:Nec2(gene name synonym)|uniprotkb:Nec-2(gene name synonym)|uniprotkb:Rpc2(gene name synonym) psi-mi:7b2_rat(display_long)|uniprotkb:Secretory granule endocrine protein I(gene name synonym)|uniprotkb:Secretogranin-5(gene name synonym)|uniprotkb:Secretogranin V(gene name synonym)|uniprotkb:Scg5(gene name)|psi-mi:Scg5(display_short)|uniprotkb:Sgne1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2006) imex:IM-14516|pubmed:16286464 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-988277|imex:IM-14516-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030070"(insulin processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0034230"(enkephalin processing)|go:"GO:0034231"(islet amyloid polypeptide processing)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|ensembl:ENSRNOG00000005438(gene)|ensembl:ENSRNOT00000007249(transcript)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|rgd:3273|refseq:NP_036878.1 go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030141"(secretory granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0051082"(unfolded protein binding)|rgd:3669|refseq:NP_037307.1|interpro:IPR007945(Neuroendocrine 7B2 precursor) psi-mi:"MI:0469"(intact) - - figure legend:Figure 2A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-rin_5f)|taxid:10116(Rattus norvegicus) - 2006/08/14 2014/10/16 rogid:qUwGjsxB1A9uaDAAO8BczhkyoOY10116 rogid:eObAai+IWpXoSFmjZYvgbVhIV1010116 intact-crc:E55FEDB78486827C|rigid:5iKXwom3iBLy5hr13X0atuxiMtg false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27682 uniprotkb:P28841 intact:EBI-988232 intact:EBI-988244|ensembl:ENSRNOP00000007249 psi-mi:7b2_rat(display_long)|uniprotkb:Secretory granule endocrine protein I(gene name synonym)|uniprotkb:Secretogranin-5(gene name synonym)|uniprotkb:Secretogranin V(gene name synonym)|uniprotkb:Scg5(gene name)|psi-mi:Scg5(display_short)|uniprotkb:Sgne1(gene name synonym) psi-mi:nec2_rat(display_long)|uniprotkb:Prohormone convertase 2(gene name synonym)|uniprotkb:Proprotein convertase 2(gene name synonym)|uniprotkb:KEX2-like endoprotease 2(gene name synonym)|uniprotkb:Pcsk2(gene name)|psi-mi:Pcsk2(display_short)|uniprotkb:Nec2(gene name synonym)|uniprotkb:Nec-2(gene name synonym)|uniprotkb:Rpc2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2006) imex:IM-14516|pubmed:16286464 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-988287|imex:IM-14516-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030141"(secretory granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0051082"(unfolded protein binding)|rgd:3669|refseq:NP_037307.1|interpro:IPR007945(Neuroendocrine 7B2 precursor) interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030070"(insulin processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0034230"(enkephalin processing)|go:"GO:0034231"(islet amyloid polypeptide processing)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|ensembl:ENSRNOG00000005438(gene)|ensembl:ENSRNOT00000007249(transcript)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|rgd:3273|refseq:NP_036878.1 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2A|comment:The authors concluded that non-phosphorylated 7B2 protein coimmunoprecipitated with PC2 protein.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-att_20)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:eObAai+IWpXoSFmjZYvgbVhIV1010116 rogid:qUwGjsxB1A9uaDAAO8BczhkyoOY10116 intact-crc:C2A12A344911D8F8|rigid:5iKXwom3iBLy5hr13X0atuxiMtg false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27682 uniprotkb:P28841 intact:EBI-988232 intact:EBI-988244|ensembl:ENSRNOP00000007249 psi-mi:7b2_rat(display_long)|uniprotkb:Secretory granule endocrine protein I(gene name synonym)|uniprotkb:Secretogranin-5(gene name synonym)|uniprotkb:Secretogranin V(gene name synonym)|uniprotkb:Scg5(gene name)|psi-mi:Scg5(display_short)|uniprotkb:Sgne1(gene name synonym) psi-mi:nec2_rat(display_long)|uniprotkb:Prohormone convertase 2(gene name synonym)|uniprotkb:Proprotein convertase 2(gene name synonym)|uniprotkb:KEX2-like endoprotease 2(gene name synonym)|uniprotkb:Pcsk2(gene name)|psi-mi:Pcsk2(display_short)|uniprotkb:Nec2(gene name synonym)|uniprotkb:Nec-2(gene name synonym)|uniprotkb:Rpc2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2006) imex:IM-14516|pubmed:16286464 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-988296|imex:IM-14516-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030141"(secretory granule)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0051082"(unfolded protein binding)|rgd:3669|refseq:NP_037307.1|interpro:IPR007945(Neuroendocrine 7B2 precursor) interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030070"(insulin processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0034230"(enkephalin processing)|go:"GO:0034231"(islet amyloid polypeptide processing)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|ensembl:ENSRNOG00000005438(gene)|ensembl:ENSRNOT00000007249(transcript)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|rgd:3273|refseq:NP_036878.1 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2A|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-att_20)|taxid:10090(Mus musculus) - 2006/08/14 2014/10/16 rogid:eObAai+IWpXoSFmjZYvgbVhIV1010116 rogid:qUwGjsxB1A9uaDAAO8BczhkyoOY10116 intact-crc:3BD99773B5C1D5FA|rigid:5iKXwom3iBLy5hr13X0atuxiMtg false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)