#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UHN1	uniprotkb:P54098	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852658	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	-	-	-	comment:A mutated form of POL2 in which residues 147-178 are mutated to glycine are used in this experiment.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	intact-crc:A3B72B1737E3CF41|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	sufficient binding region:1-146,179-485	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHN1	uniprotkb:Q9UHN1	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852684	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	go:"GO:0042803"(protein homodimerization activity)	-	-	comment:Observed molecular mass 105,747kDa, calculated molecular mass 106,916	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	intact-crc:BD0F8DB6C5FD6879|rigid:UJ+vmcTB9W1Cji1M2y6WgeZ1aN0	false	necessary binding region:147-178	necessary binding region:147-178	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHN1	uniprotkb:P54098	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852726	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	go:"GO:0005760"(gamma DNA polymerase complex)	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	intact-crc:EA6BA3BF8966BB9C|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	-	his tag:?-?	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54098	uniprotkb:Q9UHN1	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852738	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	go:"GO:0005760"(gamma DNA polymerase complex)	-	-	comment:Kd is measure of POLA interacting with POLG2 homodimer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	intact-crc:61336C780B1911DD|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	his tag:?-?	-	1	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHN1	uniprotkb:P54098	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852755	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	-	-	-	comment:Kd is measure of POLA interacting with POLG monomer|comment:A POLG2 mutant lacking the region required for dimerisation can still bind to POLG in a monomeric state.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	intact-crc:4C14BACFF9CB2BAF|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	sufficient binding region:179-485,1-146	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHN1	uniprotkb:P54098	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852789	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	-	-	-	comment:Kd is presumably the measure of POLA interacting with POLG2 homodimer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	intact-crc:B00E314665877F45|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	-	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UHN1	uniprotkb:P54098	intact:EBI-852642|uniprotkb:O00419|uniprotkb:Q0IJ81|uniprotkb:Q96GW2|uniprotkb:Q9UK35|uniprotkb:Q9UK94|ensembl:ENSP00000442563	intact:EBI-852624|uniprotkb:Q8NFM2|uniprotkb:Q92515|ensembl:ENSP00000268124|ensembl:ENSP00000399851	psi-mi:dpog2_human(display_long)|uniprotkb:Mitochondrial DNA polymerase accessory subunit(gene name synonym)|uniprotkb:PolG-beta(gene name synonym)|uniprotkb:MtPolB(gene name synonym)|uniprotkb:DNA polymerase gamma accessory 55 kDa subunit(gene name synonym)|uniprotkb:POLG2(gene name)|psi-mi:POLG2(display_short)|uniprotkb:MTPOLB(gene name synonym)	psi-mi:dpog1_human(display_long)|uniprotkb:Mitochondrial DNA polymerase catalytic subunit(gene name synonym)|uniprotkb:PolG-alpha(gene name synonym)|uniprotkb:POLG(gene name)|psi-mi:POLG(display_short)|uniprotkb:MDP1(gene name synonym)|uniprotkb:POLG1(gene name synonym)|uniprotkb:POLGA(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Yakubovskaya et al. (2006)	pubmed:16263719	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-852806	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009146.2|ensembl:ENSG00000256525(gene)|ensembl:ENST00000539111(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR004154(Anticodon-binding)|interpro:IPR027030|interpro:IPR027031|interpro:IPR036621|interpro:IPR042064|mint:Q9UHN1|rcsb pdb:2G4C|rcsb pdb:3IKL|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53|reactome:R-HSA-2151201	refseq:NP_001119603.1|refseq:NP_002684.1|ensembl:ENSG00000140521(gene)|ensembl:ENST00000268124(transcript)|ensembl:ENST00000442287(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005760"(gamma DNA polymerase complex)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0007568"(aging)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043195"(terminal bouton)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071333"(cellular response to glucose stimulus)|interpro:IPR001098(DNA-directed DNA polymerase, family A)|interpro:IPR002297(DNA-directed DNA-polymerase, family A, mitochondria)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR019760|interpro:IPR041336|interpro:IPR043502|mint:P54098|rcsb pdb:3IKM|rcsb pdb:4ZTU|rcsb pdb:4ZTZ|rcsb pdb:5C51|rcsb pdb:5C52|rcsb pdb:5C53	-	-	-	comment:Kd is a measure of POLA interacting with POLG monomer|comment:A POLG2 mutant lacking the region required for dimerisation can still bind to POLG in a monomeric state.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/02/15	2014/10/16	rogid:41rQkZKot9P54MT7OJ7nGHer8BI9606	rogid:Gt8NCLdg0R/XLyFsovnrnLrzb/A9606	intact-crc:437DD28810874508|rigid:9nxNZK2Tsv4Tk1CtXubVV2NCRys	false	sufficient binding region:179-485,1-146	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)