#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7Z412 uniprotkb:O43933 intact:EBI-752057|uniprotkb:Q7Z413|uniprotkb:Q7Z414|uniprotkb:Q7Z415|uniprotkb:Q7Z416|uniprotkb:Q96B12|uniprotkb:Q9NWQ0|uniprotkb:Q9NXU0|uniprotkb:F6UBB5|ensembl:ENSP00000331106|ensembl:ENSP00000382648 intact:EBI-988601|uniprotkb:Q96S71|uniprotkb:Q96S72|uniprotkb:Q96S73|uniprotkb:Q99994|ensembl:ENSP00000248633|uniprotkb:A8KA90|uniprotkb:A4D1G3|uniprotkb:B4DIM7|uniprotkb:E9PE75 psi-mi:pex26_human(display_long)|uniprotkb:PEX26(gene name)|psi-mi:PEX26(display_short)|uniprotkb:Peroxin-26(gene name synonym) psi-mi:pex1_human(display_long)|uniprotkb:Peroxin-1(gene name synonym)|uniprotkb:Peroxisome biogenesis disorder protein 1(gene name synonym)|uniprotkb:PEX1(gene name)|psi-mi:PEX1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Furuki et al. (2006) imex:IM-14443|pubmed:16257970 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-980993|imex:IM-14443-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121121.1|refseq:NP_001186248.1|refseq:NP_060399.1|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0051117"(ATPase binding)|interpro:IPR010797(Pex26)|reactome:R-HSA-9033241|reactome:R-HSA-9603798|ensembl:ENSG00000215193(gene)|ensembl:ENST00000329627(transcript)|ensembl:ENST00000399744(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0044877"(protein-containing complex binding) refseq:NP_001269606.1|refseq:NP_001269607.1|refseq:NP_000457.1|ensembl:ENSG00000127980(gene)|ensembl:ENST00000248633(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060152"(microtubule-based peroxisome localization)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015342(Peroxisome biogenesis factor 1, N-terminal)|interpro:IPR015343(Peroxisome biogenesis factor 1, alpha/beta)|interpro:IPR025653|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:O43933|reactome:R-HSA-9033241|go:"GO:0070062"(extracellular exosome) psi-mi:"MI:0469"(intact) - - figure legend:Figure 4|comment:Deletion of the first 96 amino acids of Pex26 severly reduced binding of Pex6. Interaction between Px26 and Pex1 was decreased by the following mutations to the wild type Pex26 amino acid sequence; gly89arg, arg98trp, lue45pro, deletion of first 96 amino acids, leu153val and deletion of cys at position 861. Also mutants containingFLAG-Pex26pT35insC, FLAG-Pex26pG255insT, and FLAG-Pex26pintG231T, encompassed 113-, 113-, and 159-amino acid long sequences that contained only 11, 85, and 77 authentic residues from the N terminus of Pex26p, respectively, also showed decreased interaction with Pex26.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/08/03 2014/10/16 rogid:MI3L70cyRkYVwjs2s79fCeA4nO49606 rogid:tc6YxVhySlqqv5/zhBkZ5pvv6/M9606 intact-crc:406212FA80E058AE|rigid:E6PXVwrptWlLfAzQXh3ORg7dwiA false flag tag:n-n ha tag:?-?|sufficient binding region:78-1283 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z412 uniprotkb:Q13608 intact:EBI-752057|uniprotkb:Q7Z413|uniprotkb:Q7Z414|uniprotkb:Q7Z415|uniprotkb:Q7Z416|uniprotkb:Q96B12|uniprotkb:Q9NWQ0|uniprotkb:Q9NXU0|uniprotkb:F6UBB5|ensembl:ENSP00000331106|ensembl:ENSP00000382648 intact:EBI-988581|ensembl:ENSP00000303511|uniprotkb:Q8WYQ2|uniprotkb:Q99476|uniprotkb:Q8WYQ0|uniprotkb:Q8WYQ1|uniprotkb:Q5T8W1 psi-mi:pex26_human(display_long)|uniprotkb:PEX26(gene name)|psi-mi:PEX26(display_short)|uniprotkb:Peroxin-26(gene name synonym) psi-mi:pex6_human(display_long)|uniprotkb:Peroxisomal-type ATPase 1(gene name synonym)|uniprotkb:Peroxisomal biogenesis factor 6(gene name synonym)|uniprotkb:Peroxin-6(gene name synonym)|uniprotkb:PEX6(gene name)|psi-mi:PEX6(display_short)|uniprotkb:PXAAA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Furuki et al. (2006) imex:IM-14443|pubmed:16257970 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-980993|imex:IM-14443-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121121.1|refseq:NP_001186248.1|refseq:NP_060399.1|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0051117"(ATPase binding)|interpro:IPR010797(Pex26)|reactome:R-HSA-9033241|reactome:R-HSA-9603798|ensembl:ENSG00000215193(gene)|ensembl:ENST00000329627(transcript)|ensembl:ENST00000399744(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0044877"(protein-containing complex binding) go:"GO:0097733"(photoreceptor cell cilium)|ensembl:ENSG00000124587(gene)|ensembl:ENST00000304611(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|refseq:NP_000278.3|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|reactome:R-HSA-9033241|refseq:NP_001303242.1 psi-mi:"MI:0469"(intact) - - figure legend:Figure 4|comment:Deletion of the first 96 amino acids of Pex26 severly reduced binding of Pex6. Interaction between Px26 and Pex1 was decreased by the following mutations to the wild type Pex26 amino acid sequence; gly89arg, arg98trp, lue45pro, deletion of first 96 amino acids, leu153val and deletion of cys at position 861. Also mutants containingFLAG-Pex26pT35insC, FLAG-Pex26pG255insT, and FLAG-Pex26pintG231T, encompassed 113-, 113-, and 159-amino acid long sequences that contained only 11, 85, and 77 authentic residues from the N terminus of Pex26p, respectively, also showed decreased interaction with Pex26.|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/08/03 2014/10/16 rogid:MI3L70cyRkYVwjs2s79fCeA4nO49606 rogid:x0FdZPwa94aM+EBSwTl7BJ6cxZA9606 intact-crc:406212FA80E058AE|rigid:E6PXVwrptWlLfAzQXh3ORg7dwiA false flag tag:n-n ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)