#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q4W8J9 uniprotkb:P00735 intact:EBI-990838 intact:EBI-990806|uniprotkb:Q3MHK7 psi-mi:q4w8j9_staau(display_long)|uniprotkb:coa(gene name)|psi-mi:coa(display_short) psi-mi:thrb_bovin(display_long)|uniprotkb:Coagulation factor II(gene name synonym)|uniprotkb:F2(gene name)|psi-mi:F2(display_short) psi-mi:"MI:0114"(x-ray crystallography) Friedrich et al. (2006) imex:IM-14529|pubmed:16230338 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-990836|rcsb pdb:2a1d|imex:IM-14529-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|interpro:IPR043071|interpro:IPR043072 interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1A0H|rcsb pdb:1AVG|rcsb pdb:1BBR|rcsb pdb:1ETR|rcsb pdb:1ETS|rcsb pdb:1ETT|rcsb pdb:1HRT|rcsb pdb:1ID5|rcsb pdb:1MKW|rcsb pdb:1MKX|rcsb pdb:1NL1|rcsb pdb:1NL2|rcsb pdb:1TBQ|rcsb pdb:1TBR|rcsb pdb:1TOC|rcsb pdb:1UCY|rcsb pdb:1UVT|rcsb pdb:1UVU|rcsb pdb:1VIT|rcsb pdb:1YCP|rcsb pdb:2A1D|rcsb pdb:2HPP|rcsb pdb:2ODY|rcsb pdb:2PF1|rcsb pdb:2PF2|rcsb pdb:2SPT|rcsb pdb:3PMA|rcsb pdb:3PMB|refseq:NP_776302.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0006953"(acute-phase response)|go:"GO:0030168"(platelet activation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0051258"(protein polymerization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|refseq:XP_015330343.1|dip:DIP-6099N - - - figure legend:3|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/17 2014/10/16 rogid:/4yLvFVGhOLK3HUT5t4yg2cz8gY1280 rogid:9ECy7nfKNLKZmV1363Tm6qgW7jo9913 intact-crc:612176EBC9E92C04|rigid:te0mWXc3lynS0kA1jN75zXgCN9Q false sufficient binding region:1-325 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q4W8J9 uniprotkb:P00735 intact:EBI-990838 intact:EBI-990806|uniprotkb:Q3MHK7 psi-mi:q4w8j9_staau(display_long)|uniprotkb:coa(gene name)|psi-mi:coa(display_short) psi-mi:thrb_bovin(display_long)|uniprotkb:Coagulation factor II(gene name synonym)|uniprotkb:F2(gene name)|psi-mi:F2(display_short) psi-mi:"MI:0405"(competition binding) Friedrich et al. (2006) imex:IM-14529|pubmed:16230338 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-992505|imex:IM-14529-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014874(Staphylcoagulse-N)|interpro:IPR001443(Staphylocoagulase)|interpro:IPR043071|interpro:IPR043072 interpro:IPR035972|interpro:IPR037111|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1A0H|rcsb pdb:1AVG|rcsb pdb:1BBR|rcsb pdb:1ETR|rcsb pdb:1ETS|rcsb pdb:1ETT|rcsb pdb:1HRT|rcsb pdb:1ID5|rcsb pdb:1MKW|rcsb pdb:1MKX|rcsb pdb:1NL1|rcsb pdb:1NL2|rcsb pdb:1TBQ|rcsb pdb:1TBR|rcsb pdb:1TOC|rcsb pdb:1UCY|rcsb pdb:1UVT|rcsb pdb:1UVU|rcsb pdb:1VIT|rcsb pdb:1YCP|rcsb pdb:2A1D|rcsb pdb:2HPP|rcsb pdb:2ODY|rcsb pdb:2PF1|rcsb pdb:2PF2|rcsb pdb:2SPT|rcsb pdb:3PMA|rcsb pdb:3PMB|refseq:NP_776302.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0006953"(acute-phase response)|go:"GO:0030168"(platelet activation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0051258"(protein polymerization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|interpro:IPR000001(Kringle)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|refseq:XP_015330343.1|dip:DIP-6099N psi-mi:"MI:0469"(intact) - - figure legend:2|dataset:BioCreative - Critical Assessment of Information Extraction systems in Biology|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/08/17 2014/10/16 rogid:/4yLvFVGhOLK3HUT5t4yg2cz8gY1280 rogid:9ECy7nfKNLKZmV1363Tm6qgW7jo9913 intact-crc:A8FE771D8BF10222|rigid:te0mWXc3lynS0kA1jN75zXgCN9Q false sufficient binding region:1-325 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)