#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48764	uniprotkb:Q6P0Q8	intact:EBI-7816923|ensembl:ENSP00000264938|uniprotkb:Q3MIW3|intact:MINT-1787470|uniprotkb:B7ZKR2|uniprotkb:E9PF67	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:sl9a3_human(display_long)|uniprotkb:SLC9A3(gene name)|psi-mi:SLC9A3(display_short)|uniprotkb:NHE3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2006)	pubmed:16159897|mint:MINT-5217945	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7816918|mint:MINT-1892385	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271280.1|ensembl:ENSG00000066230(gene)|ensembl:ENST00000264938(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006811"(ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018410|interpro:IPR018422|reactome:R-HSA-425986|refseq:NP_004165.2|mint:MINT-1892387(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-1892386(identity)	-	comment:mint|function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/04/27	2014/10/16	rogid:A21OgPigqdmnTkpT3oZqwaGtN2w9606	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:7352DBAFC0DB90BE|rigid:dDzREIZPxo7au1EteeCsOQHl3kU	false	tag:?-?(MINT-1892392)|binding-associated region:475-832(MINT-1892399)	binding-associated region:970-1734(MINT-1892409)|tag:?-?(MINT-1892402)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P48764	uniprotkb:Q6P0Q8	intact:EBI-7816923|ensembl:ENSP00000264938|uniprotkb:Q3MIW3|intact:MINT-1787470|uniprotkb:B7ZKR2|uniprotkb:E9PF67	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:sl9a3_human(display_long)|uniprotkb:SLC9A3(gene name)|psi-mi:SLC9A3(display_short)|uniprotkb:NHE3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0096"(pull down)	Wang et al. (2006)	pubmed:16159897|mint:MINT-5217945	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7816994|mint:MINT-1892413	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271280.1|ensembl:ENSG00000066230(gene)|ensembl:ENST00000264938(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006811"(ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018410|interpro:IPR018422|reactome:R-HSA-425986|refseq:NP_004165.2|mint:MINT-1892414(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-1892424(identity)	-	comment:mint|function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/27	2014/10/16	rogid:A21OgPigqdmnTkpT3oZqwaGtN2w9606	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:3CD16BFDF9EE7AC0|rigid:dDzREIZPxo7au1EteeCsOQHl3kU	false	his tag:?-?(MINT-1892422)|binding-associated region:475-832(MINT-1892415)	binding-associated region:412-1455(IPR000719)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q28362	uniprotkb:Q6P0Q8	intact:EBI-7817027|intact:MINT-1892475	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:sl9a3_didvi(display_long)|uniprotkb:SLC9A3(gene name)|psi-mi:SLC9A3(display_short)|uniprotkb:NHE3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Wang et al. (2006)	pubmed:16159897|mint:MINT-5217945	taxid:9267(north american oposs)|taxid:9267(Didelphis virginiana)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7817046|mint:MINT-1892443	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR018410|interpro:IPR018422|mint:MINT-1892444(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-1892453(identity)	-	comment:mint|function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:mint	taxid:38605(didma-okp)|taxid:38605(Opossum kidney cell line)	-	2006/04/27	2014/10/16	rogid:h/DFX41QjeSfdFV4sXwc84eZt5o9267	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:C9E9DFE595F0808C|rigid:JtWC/zOT57amSX3yYByoVMOFfi0	false	binding-associated region:c-c(MINT-1892445)	binding-associated region:947-1734(MINT-1892454)|his tag:?-?(MINT-1892470)	1	1	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q28362	uniprotkb:Q6P0Q8	intact:EBI-7817027|intact:MINT-1892475	intact:EBI-493777|uniprotkb:O94899|uniprotkb:Q5VT07|uniprotkb:Q5VT08|uniprotkb:Q7LGC4|uniprotkb:Q8NDG1|uniprotkb:Q96B94|uniprotkb:Q9BYE8|ensembl:ENSP00000354671	psi-mi:sl9a3_didvi(display_long)|uniprotkb:SLC9A3(gene name)|psi-mi:SLC9A3(display_short)|uniprotkb:NHE3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger 3"(gene name synonym)|uniprotkb:Solute carrier family 9 member 3(gene name synonym)	psi-mi:mast2_human(display_long)|uniprotkb:KIAA0807(gene name synonym)|uniprotkb:MAST205(gene name synonym)|uniprotkb:MAST2(gene name)|psi-mi:MAST2(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Wang et al. (2006)	pubmed:16159897|mint:MINT-5217945	taxid:9267(north american oposs)|taxid:9267(Didelphis virginiana)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7817075|mint:MINT-1892486	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|interpro:IPR018410|interpro:IPR018422|mint:MINT-1892487(identity)	refseq:NP_055927.2|refseq:NP_001306174.1|ensembl:ENSG00000086015(gene)|ensembl:ENST00000361297(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015022(Region of unknown function DUF1908)|interpro:IPR023142|interpro:IPR028779|interpro:IPR036034|interpro:IPR037711|interpro:IPR041489|rcsb pdb:2KQF|rcsb pdb:2KYL|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008271(Serine/threonine protein kinase, active site)|mint:MINT-1892494(identity)	-	comment:mint|function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F7|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/27	2014/10/16	rogid:h/DFX41QjeSfdFV4sXwc84eZt5o9267	rogid:auQ5z3m/wafM/oomfF1/ygEFC9E9606	intact-crc:C7B463CD01B5D32E|rigid:JtWC/zOT57amSX3yYByoVMOFfi0	false	binding-associated region:c-c(MINT-1892488)|tag:?-?(MINT-1892511)	his tag:?-?(MINT-1892503)|binding-associated region:412-800(IPR000719)	1	1	psi-mi:"MI:0039"(edman degradation)	psi-mi:"MI:0078"(nucleotide sequence identification)