#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14122	uniprotkb:O60016	intact:EBI-904890|uniprotkb:Q9USB6|ensemblfungi:"SPAC3A11.08.1:pep"	intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep"	psi-mi:cul4_schpo(display_long)|uniprotkb:pcu4(gene name)|psi-mi:pcu4(display_short)|uniprotkb:cul4(gene name synonym)|uniprotkb:SPAC3A11.08(orf name)	psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111919|imex:IM-19908-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696395|reactome:R-SPO-5696400|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR033044|refseq:NP_594195.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-SPO-110314|reactome:R-SPO-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:SPAC3A11.08(gene)|ensemblfungi:SPAC3A11.08.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043494"(CLRC complex)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N	-	-	crc64:53C3EC87BCBA51FF	figure legend:Fig. 1b, S1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:gJJvtfEApiJnXSMsi9Mk0W3VjO0284812	rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812	intact-crc:FB92C868CDECABDE|rigid:pe08LGkfgO3CMW/hIr2hbEUDEMg	false	-	flag tag:n-n	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q10426	uniprotkb:O60016	intact:EBI-1111936|uniprotkb:Q9USN9|uniprotkb:Q9UUL7|ensemblfungi:"SPCC11E10.08.1:pep"	intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep"	psi-mi:rik1_schpo(display_long)|uniprotkb:rik1(gene name)|psi-mi:rik1(display_short)|uniprotkb:SPCC11E10.08(orf name)|uniprotkb:Silencing protein rik1(gene name synonym)	psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111957|imex:IM-19908-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588204.1|ensemblfungi:SPCC11E10.08(gene)|ensemblfungi:SPCC11E10.08.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006281"(DNA repair)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|dip:DIP-35634N	refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N	-	crc64:0C76BB59E1215BF1	crc64:53C3EC87BCBA51FF	figure legend:Fig. 1b, S1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:t1LBwviHXmmvKSMrLCcs2QCSp2Q284812	rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812	intact-crc:EAC491B8D87F2974|rigid:+N9m8J9wKLY0m07zsHMGn79X/jE	false	-	flag tag:n-n	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q10426	uniprotkb:O14122	intact:EBI-1111936|uniprotkb:Q9USN9|uniprotkb:Q9UUL7|ensemblfungi:"SPCC11E10.08.1:pep"	intact:EBI-904890|uniprotkb:Q9USB6|ensemblfungi:"SPAC3A11.08.1:pep"	psi-mi:rik1_schpo(display_long)|uniprotkb:rik1(gene name)|psi-mi:rik1(display_short)|uniprotkb:SPCC11E10.08(orf name)|uniprotkb:Silencing protein rik1(gene name synonym)	psi-mi:cul4_schpo(display_long)|uniprotkb:pcu4(gene name)|psi-mi:pcu4(display_short)|uniprotkb:cul4(gene name synonym)|uniprotkb:SPAC3A11.08(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111964|imex:IM-19908-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588204.1|ensemblfungi:SPCC11E10.08(gene)|ensemblfungi:SPCC11E10.08.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006281"(DNA repair)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|dip:DIP-35634N	reactome:R-SPO-5696395|reactome:R-SPO-5696400|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR033044|refseq:NP_594195.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-SPO-110314|reactome:R-SPO-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:SPAC3A11.08(gene)|ensemblfungi:SPAC3A11.08.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043494"(CLRC complex)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	crc64:0C76BB59E1215BF1	-	figure legend:Fig. 1f, S1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:t1LBwviHXmmvKSMrLCcs2QCSp2Q284812	rogid:gJJvtfEApiJnXSMsi9Mk0W3VjO0284812	intact-crc:5EECD7B411D0E86A|rigid:xIb7uqO6bAvGFEuvOlO7wvP+u6A	false	flag tag:n-n	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O14122	uniprotkb:O60016	intact:EBI-904890|uniprotkb:Q9USB6|ensemblfungi:"SPAC3A11.08.1:pep"	intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep"	psi-mi:cul4_schpo(display_long)|uniprotkb:pcu4(gene name)|psi-mi:pcu4(display_short)|uniprotkb:cul4(gene name synonym)|uniprotkb:SPAC3A11.08(orf name)	psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111931|imex:IM-19908-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SPO-5696395|reactome:R-SPO-5696400|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR033044|refseq:NP_594195.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-SPO-110314|reactome:R-SPO-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:SPAC3A11.08(gene)|ensemblfungi:SPAC3A11.08.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043494"(CLRC complex)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N	-	-	crc64:53C3EC87BCBA51FF	figure legend:Fig. S2b|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:gJJvtfEApiJnXSMsi9Mk0W3VjO0284812	rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812	intact-crc:C93EBB63599FE14F|rigid:pe08LGkfgO3CMW/hIr2hbEUDEMg	false	-	calmodulin binding peptide plus protein a tag:n-n	-	-	psi-mi:"MI:0363"(inferred by author)	psi-mi:"MI:0363"(inferred by author)
uniprotkb:O60016	uniprotkb:O14122	intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep"	intact:EBI-904890|uniprotkb:Q9USB6|ensemblfungi:"SPAC3A11.08.1:pep"	psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym)	psi-mi:cul4_schpo(display_long)|uniprotkb:pcu4(gene name)|psi-mi:pcu4(display_short)|uniprotkb:cul4(gene name synonym)|uniprotkb:SPAC3A11.08(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111978|imex:IM-19908-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N	reactome:R-SPO-5696395|reactome:R-SPO-5696400|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR033044|refseq:NP_594195.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-SPO-110314|reactome:R-SPO-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:SPAC3A11.08(gene)|ensemblfungi:SPAC3A11.08.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043494"(CLRC complex)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	crc64:53C3EC87BCBA51FF	-	figure legend:Fig. 1d|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812	rogid:gJJvtfEApiJnXSMsi9Mk0W3VjO0284812	intact-crc:1E74150DC3A48A3F|rigid:pe08LGkfgO3CMW/hIr2hbEUDEMg	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q10426	uniprotkb:O14122	intact:EBI-1111936|uniprotkb:Q9USN9|uniprotkb:Q9UUL7|ensemblfungi:"SPCC11E10.08.1:pep"	intact:EBI-904890|uniprotkb:Q9USB6|ensemblfungi:"SPAC3A11.08.1:pep"	psi-mi:rik1_schpo(display_long)|uniprotkb:rik1(gene name)|psi-mi:rik1(display_short)|uniprotkb:SPCC11E10.08(orf name)|uniprotkb:Silencing protein rik1(gene name synonym)	psi-mi:cul4_schpo(display_long)|uniprotkb:pcu4(gene name)|psi-mi:pcu4(display_short)|uniprotkb:cul4(gene name synonym)|uniprotkb:SPAC3A11.08(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jia et al. (2005)	pubmed:16127433|imex:IM-19908	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111986|imex:IM-19908-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_588204.1|ensemblfungi:SPCC11E10.08(gene)|ensemblfungi:SPCC11E10.08.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006281"(DNA repair)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|dip:DIP-35634N	reactome:R-SPO-5696395|reactome:R-SPO-5696400|reactome:R-SPO-6781823|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR033044|refseq:NP_594195.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|reactome:R-SPO-110314|reactome:R-SPO-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|ensemblfungi:SPAC3A11.08(gene)|ensemblfungi:SPAC3A11.08.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043494"(CLRC complex)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)	-	crc64:0C76BB59E1215BF1	-	figure legend:Fig. 1g|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/24	2014/10/16	rogid:t1LBwviHXmmvKSMrLCcs2QCSp2Q284812	rogid:gJJvtfEApiJnXSMsi9Mk0W3VjO0284812	intact-crc:F792F7DAB81797CA|rigid:xIb7uqO6bAvGFEuvOlO7wvP+u6A	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)