#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6VGS5 uniprotkb:P51142 intact:EBI-7696187|ensembl:ENSMUSP00000068629|intact:MINT-1890259|uniprotkb:Q3UVI2 intact:EBI-6257503 psi-mi:daple_mouse(display_long)|uniprotkb:Ccdc88c(gene name)|psi-mi:Ccdc88c(display_short)|uniprotkb:Daple(gene name synonym)|uniprotkb:Dvl-associating protein with a high frequency of leucine residues(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 88C(gene name synonym) psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kobayashi et al. (2005) pubmed:16026968|mint:MINT-5217834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7696182|mint:MINT-1890269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021182(gene)|ensembl:ENSMUST00000068411(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003383"(apical constriction)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031648"(protein destabilization)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR027719|interpro:IPR036872|interpro:IPR043936|refseq:NP_080957.2|mint:MINT-1890271(identity) go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-1890270(identity) - comment:mint|function:Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:mint taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo) - 2006/04/20 2014/10/16 rogid:N8Lb/xi0N2NeqnqNU6XsiAVdtWg10090 rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355 intact-crc:42E9673A006313F7|rigid:vlSM2CFzYLPA7TNNB7hJHM7B50U false binding-associated region:1152-2009(MINT-1890324)|myc tag:?-?(MINT-1890317) green fluorescent protein tag:?-?(MINT-1890332) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)