#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9QYE9-2 uniprotkb:Q9WTI7 intact:EBI-1127145|ensembl:ENSMUSP00000102662 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:q9qye9-2(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0018"(two hybrid) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1127030 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000107047(transcript) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N - - - figure legend:Figure 1 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:p6icbvCKrg7x3XMdtkxxZYp72Vw10090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:FC803917E9BAFE17|rigid:s2Jwsr8iSWHjGG8CGOWoTYi20oo false - binding-associated region:797-1063 - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P97479 uniprotkb:Q9QYE9-2 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1127145|ensembl:ENSMUSP00000102662 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:q9qye9-2(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1149574 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000107047(transcript) - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:p6icbvCKrg7x3XMdtkxxZYp72Vw10090 intact-crc:3CA586507B9CDF49|rigid:NNa//6gk2b0H35iNwCyD50YNbXg false binding-associated region:934-1071 - - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:Q9QYE9-1 uniprotkb:Q9WTI7 intact:EBI-1127141|ensembl:ENSMUSP00000078175 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:q9qye9-1(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1129951 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000079176(transcript) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N - - - figure legend:1c taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/10/25 2014/10/16 rogid:ulTOTTg84Zodax13dxctORWu8XQ10090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:C1CB9C08B28ACD24|rigid:huOzUP8b/GDGGM2448Q6D8DRe70 false green fluorescent protein tag:?-? myc tag:?-?|binding-associated region:797-1063 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QYE9-2 uniprotkb:Q9WTI7 intact:EBI-1127145|ensembl:ENSMUSP00000102662 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:q9qye9-2(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0096"(pull down) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1131624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000107047(transcript) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N - - - figure legend:1E taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:p6icbvCKrg7x3XMdtkxxZYp72Vw10090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:B363EF8A14CD03BE|rigid:s2Jwsr8iSWHjGG8CGOWoTYi20oo false 35s radiolabel:?-?|necessary binding region:70-178 binding-associated region:797-1063|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9QYE9-1 uniprotkb:Q9WTI7 intact:EBI-1127141|ensembl:ENSMUSP00000078175 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 psi-mi:q9qye9-1(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:"MI:0096"(pull down) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1148883 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000079176(transcript) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N - - - figure legend:1F|comment:"The initial GST tag of the PHR1a fragment (Q9QYE9-1) was cleaved off with thrombin." taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:ulTOTTg84Zodax13dxctORWu8XQ10090 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 intact-crc:DA0B63FF709F99EA|rigid:huOzUP8b/GDGGM2448Q6D8DRe70 false binding-associated region:1-126 binding-associated region:736-1063|glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTI7 uniprotkb:Q9QYE9-1 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 intact:EBI-1127141|ensembl:ENSMUSP00000078175 psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:q9qye9-1(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1149067 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000079176(transcript) - - - figure legend:2|comment:"The presence of 50 micromolar calcium, 100 micromolar EGTA or calmodulin (1.5-15.0 Micromolar concentrations) on did not affect the reaction." taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 rogid:ulTOTTg84Zodax13dxctORWu8XQ10090 intact-crc:B6C239BF128BE7EA|rigid:huOzUP8b/GDGGM2448Q6D8DRe70 false glutathione s tranferase tag:?-?|binding-associated region:797-1063 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WTI7 uniprotkb:Q9QYE9-1 intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54 intact:EBI-1127141|ensembl:ENSMUSP00000078175 psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short) psi-mi:q9qye9-1(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1149427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N intact:EBI-1127128(pkhb1_mouse)|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000079176(transcript) - - - figure legend:2|comment:"The presence of 50 micromolar calcium, 100 micromolar EGTA or calmodulin (1.5-15.0 Micromolar concentrations) on did not affect the reaction." taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:E25nufEJATQnH9pvQlkmAdEOAd810090 rogid:ulTOTTg84Zodax13dxctORWu8XQ10090 intact-crc:F30C77F1D676CB2E|rigid:huOzUP8b/GDGGM2448Q6D8DRe70 false 35s radiolabel:?-?|binding-associated region:797-1063 glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97479 uniprotkb:Q9QYE9 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 intact:EBI-1127128|uniprotkb:Q9QYB3|uniprotkb:Q9QYB4|uniprotkb:Q9QYD2|uniprotkb:Q9QYD3|ensembl:ENSMUSP00000078175 psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:pkhb1_mouse(display_long)|uniprotkb:Plekhb1(gene name)|psi-mi:Plekhb1(display_short)|uniprotkb:Phr1(gene name synonym)|uniprotkb:Pleckstrin homology domain retinal protein 1(gene name synonym)|uniprotkb:PH domain-containing protein in retina 1(gene name synonym)|uniprotkb:Evt1(gene name synonym)|uniprotkb:Evectin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Etournay et al. (2005) pubmed:15976448 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1149791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794 refseq:NP_001156654.1|refseq:NP_001156655.1|refseq:NP_001156656.1|refseq:NP_001156657.1|refseq:NP_001156658.1|refseq:NP_001156659.1|refseq:NP_038774.1|ensembl:ENSMUSG00000030701|ensembl:ENSMUSG00000030701|refseq:NP_001278265.1|refseq:XP_006507969.1|ensembl:ENSMUSG00000030701(gene)|ensembl:ENSMUST00000079176(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045595"(regulation of cell differentiation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039680|interpro:IPR039816|rcsb pdb:2D9V - - - figure legend:3B taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/25 2014/10/16 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 rogid:ulTOTTg84Zodax13dxctORWu8XQ10090 intact-crc:F44AA8434269DD80|rigid:S8Gvkb/8Qr3tRrrrtkp1qE+mkGI false binding-associated region:847-2215 green fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)