#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7JUF2	uniprotkb:P51140	intact:EBI-1158635|ensemblmetazoa:FBpp0087344|ensemblmetazoa:FBpp0087345	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:q7juf2_drome(display_long)|uniprotkb:dgo(gene name)|psi-mi:dgo(display_short)|uniprotkb:Dgo(gene name synonym)|uniprotkb:Dmel\CG12342(gene name synonym)|uniprotkb:"EP(2)2619"(gene name synonym)|uniprotkb:EP2619(gene name synonym)|uniprotkb:CG12342(orf name)|uniprotkb:Dmel_CG12342(orf name)|uniprotkb:DGO(gene name synonym)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0018"(two hybrid)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153574|imex:IM-19412-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBtr0088249(transcript)|ensemblmetazoa:FBtr0088250(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|ensemblmetazoa:FBgn0086898(gene)|refseq:NP_610614.1|refseq:NP_724973.1|flybase:FBgn0086898|dip:DIP-36067N	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/11/03	2014/10/16	rogid:MPZJaURLdCgFS+yN9CSwp2Mai9A7227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:558432A707B3BC21|rigid:SLIvLtei04fPHG6khpJ76Z1BfOE	false	-	sufficient binding region:200-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7JUF2	uniprotkb:P51140	intact:EBI-1158635|ensemblmetazoa:FBpp0087344|ensemblmetazoa:FBpp0087345	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:q7juf2_drome(display_long)|uniprotkb:dgo(gene name)|psi-mi:dgo(display_short)|uniprotkb:Dgo(gene name synonym)|uniprotkb:Dmel\CG12342(gene name synonym)|uniprotkb:"EP(2)2619"(gene name synonym)|uniprotkb:EP2619(gene name synonym)|uniprotkb:CG12342(orf name)|uniprotkb:Dmel_CG12342(orf name)|uniprotkb:DGO(gene name synonym)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153592|imex:IM-19412-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBtr0088249(transcript)|ensemblmetazoa:FBtr0088250(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|ensemblmetazoa:FBgn0086898(gene)|refseq:NP_610614.1|refseq:NP_724973.1|flybase:FBgn0086898|dip:DIP-36067N	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/11/03	2014/10/16	rogid:MPZJaURLdCgFS+yN9CSwp2Mai9A7227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:0365B22F6ACA7476|rigid:SLIvLtei04fPHG6khpJ76Z1BfOE	false	yellow fluorescent protein tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7JUF2	uniprotkb:P51140	intact:EBI-1158635|ensemblmetazoa:FBpp0087344|ensemblmetazoa:FBpp0087345	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:q7juf2_drome(display_long)|uniprotkb:dgo(gene name)|psi-mi:dgo(display_short)|uniprotkb:Dgo(gene name synonym)|uniprotkb:Dmel\CG12342(gene name synonym)|uniprotkb:"EP(2)2619"(gene name synonym)|uniprotkb:EP2619(gene name synonym)|uniprotkb:CG12342(orf name)|uniprotkb:Dmel_CG12342(orf name)|uniprotkb:DGO(gene name synonym)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0096"(pull down)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1153603|imex:IM-19412-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBtr0088249(transcript)|ensemblmetazoa:FBtr0088250(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|ensemblmetazoa:FBgn0086898(gene)|refseq:NP_610614.1|refseq:NP_724973.1|flybase:FBgn0086898|dip:DIP-36067N	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. 3B, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/03	2014/10/16	rogid:MPZJaURLdCgFS+yN9CSwp2Mai9A7227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:C252BB8CE2F1B970|rigid:SLIvLtei04fPHG6khpJ76Z1BfOE	false	sufficient binding region:259-440|35s radiolabel:?-?	glutathione s tranferase tag:n-n|sufficient binding region:200-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A1Z6W3	uniprotkb:P51140	intact:EBI-499699|intact:EBI-1154754|uniprotkb:A1Z6V4|uniprotkb:A1Z6V8|uniprotkb:Q9N9H6|uniprotkb:Q9U5X1|uniprotkb:Q9U5X0|ensemblmetazoa:FBpp0088115	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:pric1_drome(display_long)|uniprotkb:Protein spiny legs(gene name synonym)|uniprotkb:pk(gene name)|psi-mi:pk(display_short)|uniprotkb:CG11084(orf name)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0096"(pull down)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1154735|imex:IM-19412-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_724534.1|refseq:NP_724535.1|refseq:NP_724538.1|flybase:FBgn0003090|dip:DIP-59584N|ensemblmetazoa:FBgn0003090(gene)|ensemblmetazoa:FBtr0089044(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007164"(establishment of tissue polarity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030424"(axon)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0098930"(axonal transport)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR033723|interpro:IPR033725|interpro:IPR033726|interpro:IPR033727|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|reactome:R-DME-4608870|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. 3B, 3D, 3E|inhibition:dgo competes with pk for binding to dsh.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/03	2014/10/16	rogid:EN5xsaeVERGHBNvHW+Oxu5ov1J47227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:2B570A7EC8AC6EE0|rigid:WbJQJrBmFQqn0sFvPudajf5/KN0	false	sufficient binding region:350-1299|35s radiolabel:?-?	sufficient binding region:200-357|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51140	uniprotkb:O45030	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	intact:EBI-869122|ensemblmetazoa:FBpp0087647	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:o45030_drome(display_long)|uniprotkb:Vang(gene name)|psi-mi:Vang(display_short)|uniprotkb:stbm(gene name synonym)|uniprotkb:CG8075(orf name)	psi-mi:"MI:0096"(pull down)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1154795|imex:IM-19412-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	flybase:FBgn0015838|dip:DIP-35779N|ensemblmetazoa:FBgn0015838(gene)|ensemblmetazoa:FBtr0088566(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005109"(frizzled binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR009539(Strabismus)|reactome:R-DME-350368|reactome:R-DME-350376|reactome:R-DME-350379|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/03	2014/10/16	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	rogid:KK7iFNVimizORrJxiz5fcSV2f8c7227	intact-crc:CA53739009E20676|rigid:eAMR1+ENGhLBwu46Bhmt9Q7dkUU	false	sufficient binding region:200-357|glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7JUF2	uniprotkb:P51140	intact:EBI-1158635|ensemblmetazoa:FBpp0087344|ensemblmetazoa:FBpp0087345	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:q7juf2_drome(display_long)|uniprotkb:dgo(gene name)|psi-mi:dgo(display_short)|uniprotkb:Dgo(gene name synonym)|uniprotkb:Dmel\CG12342(gene name synonym)|uniprotkb:"EP(2)2619"(gene name synonym)|uniprotkb:EP2619(gene name synonym)|uniprotkb:CG12342(orf name)|uniprotkb:Dmel_CG12342(orf name)|uniprotkb:DGO(gene name synonym)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0096"(pull down)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1157412|imex:IM-19412-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBtr0088249(transcript)|ensemblmetazoa:FBtr0088250(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|ensemblmetazoa:FBgn0086898(gene)|refseq:NP_610614.1|refseq:NP_724973.1|flybase:FBgn0086898|dip:DIP-36067N	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/03	2014/10/16	rogid:MPZJaURLdCgFS+yN9CSwp2Mai9A7227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:2B3288A543171C03|rigid:SLIvLtei04fPHG6khpJ76Z1BfOE	false	sufficient binding region:259-927|his tag:n-n	glutathione s tranferase tag:n-n|sufficient binding region:200-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7JUF2	uniprotkb:P51140	intact:EBI-1158635|ensemblmetazoa:FBpp0087344|ensemblmetazoa:FBpp0087345	intact:EBI-499383|ensemblmetazoa:FBpp0073310|uniprotkb:Q494J5|uniprotkb:Q9VYZ9	psi-mi:q7juf2_drome(display_long)|uniprotkb:dgo(gene name)|psi-mi:dgo(display_short)|uniprotkb:Dgo(gene name synonym)|uniprotkb:Dmel\CG12342(gene name synonym)|uniprotkb:"EP(2)2619"(gene name synonym)|uniprotkb:EP2619(gene name synonym)|uniprotkb:CG12342(orf name)|uniprotkb:Dmel_CG12342(orf name)|uniprotkb:DGO(gene name synonym)	psi-mi:dsh_drome(display_long)|uniprotkb:dsh(gene name)|psi-mi:dsh(display_short)|uniprotkb:CG18361(orf name)	psi-mi:"MI:0096"(pull down)	Jenny et al. (2005)	pubmed:15937478|imex:IM-19412	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1158832|imex:IM-19412-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBtr0088249(transcript)|ensemblmetazoa:FBtr0088250(transcript)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0042067"(establishment of ommatidial planar polarity)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-450728|ensemblmetazoa:FBgn0086898(gene)|refseq:NP_610614.1|refseq:NP_724973.1|flybase:FBgn0086898|dip:DIP-36067N	refseq:NP_511118.2|flybase:FBgn0000499|ensemblmetazoa:FBgn0000499(gene)|ensemblmetazoa:FBtr0073454(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007391"(dorsal closure)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008585"(female gonad development)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0016201"(synaptic target inhibition)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035159"(regulation of tube length, open tracheal system)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035317"(imaginal disc-derived wing hair organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042067"(establishment of ommatidial planar polarity)|go:"GO:0045179"(apical cortex)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048076"(regulation of compound eye pigmentation)|go:"GO:0048477"(oogenesis)|go:"GO:0048675"(axon extension)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:1902669"(positive regulation of axon guidance)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|reactome:R-DME-201688|reactome:R-DME-2028269|reactome:R-DME-209440|reactome:R-DME-350368|reactome:R-DME-350369|reactome:R-DME-350376|reactome:R-DME-350411|reactome:R-DME-350480|reactome:R-DME-4086400|reactome:R-DME-450728|reactome:R-DME-4608870|reactome:R-DME-4641258|reactome:R-DME-4641262|reactome:R-DME-5099900|reactome:R-DME-5663220|reactome:R-DME-8856825|reactome:R-DME-8856828|interpro:IPR038207	-	-	-	figure legend:Fig. S1D|inhibition:pk competes with dgo for binding to dsh.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/03	2014/10/16	rogid:MPZJaURLdCgFS+yN9CSwp2Mai9A7227	rogid:zXo1t6bIifQ3/t3hf/MVeEuPw9A7227	intact-crc:F30F50C8B8BAEFCE|rigid:SLIvLtei04fPHG6khpJ76Z1BfOE	false	his tag:n-n|sufficient binding region:259-927|35s radiolabel:?-?	glutathione s tranferase tag:n-n|sufficient binding region:200-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)