#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q00772 uniprotkb:P02829 intact:EBI-17372|uniprotkb:D3DKX7|ensemblfungi:YHR030C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:slt2_yeast(display_long)|uniprotkb:YHR030C(locus name)|uniprotkb:SLT2(gene name)|psi-mi:SLT2(display_short)|uniprotkb:MPK1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011895.1|sgd:S000001072|ensemblfungi:YHR030C(gene)|ensemblfungi:YHR030C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043332"(mating projection tip)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0090364"(regulation of proteasome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-881907|dip:DIP-1448N|reactome:R-SCE-198765|reactome:R-SCE-4086398 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:559A3E0D3EBDE5F9 crc64:D7C35676D668FB63 agonist:"Heat shock (39 degree celsius/1 hour) or caffine (8mM/1 hour) treatments were demostrated to increase Hsp82 (E33A) and SLT2 interaction using beta-galactosidase assay." taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:1dJe7ldR8bi2mbvPugrkZAHrrVw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:21DCE534865C5E05|rigid:WI6ozuzkkSWp8eeV32YiFjrmtfI false mutation disrupting interaction:192-192,190-190|binding-associated region:1-328 mutation disrupting interaction:79-79|mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15442 uniprotkb:P02829 intact:EBI-330|uniprotkb:D6VSR3|ensemblfungi:YDR283C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gcn2_yeast(display_long)|uniprotkb:GCN2(gene name)|psi-mi:GCN2(display_short)|uniprotkb:AAS1(gene name synonym)|uniprotkb:General control non-derepressible protein 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase GCN2(gene name synonym)|uniprotkb:YDR283C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002691|refseq:NP_010569.3|dip:DIP-2346N|ensemblfungi:YDR283C(gene)|ensemblfungi:YDR283C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|mint:P15442|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043621"(protein self-association)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071232"(cellular response to histidine)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR000719(Protein kinase, core)|interpro:IPR006575(RWD)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR016255(Serine/threonine-protein kinase, GCN2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024435|interpro:IPR036621|interpro:IPR041715|rcsb pdb:1ZXE|rcsb pdb:1ZY4|rcsb pdb:1ZY5|rcsb pdb:1ZYC|rcsb pdb:1ZYD|rcsb pdb:2YZ0|rcsb pdb:4OTM ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:1F56E4B046D52325 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:d8fcrr70iKA6pK9Z4yqMQsPTAWI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:3F3A8E44FFC13934|rigid:VuGAA5apAoGFTjQJ4PxCa7dbQcY false - mutation increasing interaction:79-79|mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06101 uniprotkb:P02829 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:0DF0C923158A2526 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BF03464E2079EBAE|rigid:lF7fL9pXtAr/+8vVL2Yry4Hi0JM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33313 uniprotkb:P02829 intact:EBI-4806|uniprotkb:Q02125|uniprotkb:D6VQF0|ensemblfungi:YBR155W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cns1_yeast(display_long)|uniprotkb:CNS1(gene name)|psi-mi:CNS1(display_short)|uniprotkb:YBR155W(locus name)|uniprotkb:YBR1205(orf name)|uniprotkb:Cyclophilin seven suppressor 1(gene name synonym)|uniprotkb:STI1 stress-inducible protein homolog(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009713.1|sgd:S000000359|dip:DIP-1271N|mint:P33313|ensemblfungi:YBR155W(gene)|ensemblfungi:YBR155W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044059|rcsb pdb:6HFM|rcsb pdb:6HFT ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:742F8254DFDB02A6 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:3vEtWsrh/ufn1qHwPkr6Iz+6qCs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:C4158C697C5D387F|rigid:MDptorukKzZlJ7r+wS+0Udo0EsA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:Q12449 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH - crc64:D7C35676D668FB63 crc64:06DF6B40EB5050BE - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 intact-crc:269A183CCC37BD59|rigid:JXPgQTz4kG+0/FTrocQ0RT+GLfw false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25294 uniprotkb:P02829 intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:642D3709C0FD5682 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:5D91E9CB4B920619|rigid:Ct1fPK0qh2n+aWuvAcWYaV6IcIM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P28707 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-26838|uniprotkb:D6VXH2|ensemblfungi:YKL117W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:sba1_yeast(display_long)|uniprotkb:YKL518(orf name)|uniprotkb:YKL117W(locus name)|uniprotkb:SBA1(gene name)|psi-mi:SBA1(display_short) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_012805.1|sgd:S000001600|mint:P28707|dip:DIP-2311N|ensemblfungi:YKL117W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051972"(regulation of telomerase activity)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|rcsb pdb:2CG9|reactome:R-SCE-2162123|reactome:R-SCE-3371511|ensemblfungi:YKL117W(gene) - crc64:D7C35676D668FB63 crc64:C51CDE30BF2FA945 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:hwQEjV3B0/hBXv4hCsRrWTaFRBY559292 intact-crc:AF93A393431051F3|rigid:n+fx9RKJslfvASS0fdWZLWrNfTQ false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P15705 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 - crc64:D7C35676D668FB63 crc64:CF8A85C2BBD3C44C - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 intact-crc:7AB3EB05F0BA8151|rigid:F9Ycrco6xgCMLu5p0ywm4wiQ6RI false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25491 uniprotkb:P02829 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:E4539F3618DD9CF2 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7A7658CAD2C3F7E8|rigid:1uodejK/INCbqFGkyRwKjliZNYE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32589 uniprotkb:P02829 intact:EBI-8648|uniprotkb:D6W3R1|ensemblfungi:YPL106C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hsp7f_yeast(display_long)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)|uniprotkb:Chaperone protein MSI3(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015219.1|sgd:S000006027|mint:P32589|dip:DIP-6645N|ensemblfungi:YPL106C(gene)|ensemblfungi:YPL106C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006914"(autophagy)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6558259111B0BC38 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:16yTg05haoflKGNZTW4EqC7FSs0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:DEC5C8C6DF559B38|rigid:sw/BhKn2xkRGT4b4Zrpa8EoTC8Y false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CS82 uniprotkb:P02829 intact:EBI-5419|uniprotkb:Q6BD21|uniprotkb:Q06574|intact:EBI-3670926|uniprotkb:P12351|uniprotkb:P0CE42 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hap1_yeasx(display_long)|uniprotkb:HAP1(gene name)|psi-mi:HAP1(display_short)|uniprotkb:CYP1(gene name synonym)|uniprotkb:Heme activator protein 1(gene name synonym)|uniprotkb:CYP1 activatory protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|mint:P0CS82|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1HWT|rcsb pdb:1PYC|rcsb pdb:1QP9|rcsb pdb:2HAP ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:4V/piX51z+5Q4cOO+WEiZMQ3j604932 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7D31BCFB9099B174|rigid:s6Tp/Wd1Im+rfhql3XruU96xnIQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P23561 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:"MI:0018"(two hybrid) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 - crc64:D7C35676D668FB63 crc64:E9E0DF27114EEEEF - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 intact-crc:0F551DF5C99C6EC4|rigid:04rksDuQCUZ0III40FLuzCB43Gw false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00772 uniprotkb:P02829 intact:EBI-17372|uniprotkb:D3DKX7|ensemblfungi:YHR030C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:slt2_yeast(display_long)|uniprotkb:YHR030C(locus name)|uniprotkb:SLT2(gene name)|psi-mi:SLT2(display_short)|uniprotkb:MPK1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011895.1|sgd:S000001072|ensemblfungi:YHR030C(gene)|ensemblfungi:YHR030C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043332"(mating projection tip)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0090364"(regulation of proteasome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-881907|dip:DIP-1448N|reactome:R-SCE-198765|reactome:R-SCE-4086398 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:559A3E0D3EBDE5F9 crc64:D7C35676D668FB63 comment:"The authors state that caffine (8mM\1 hour) or heat shock (39 degree celsius/1 hour) treatments increased interaction between SLT2 and wild type Hsp82 and Hsp82 (E33A) mutant." taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:1dJe7ldR8bi2mbvPugrkZAHrrVw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A1B523831FBF0EF5|rigid:WI6ozuzkkSWp8eeV32YiFjrmtfI false mutation disrupting interaction:190-190,192-192 his tag:c-c|mutation disrupting interaction:79-79|mutation increasing interaction:33-33 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P02829 uniprotkb:P60010 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026 - crc64:D7C35676D668FB63 crc64:87AC19B0B0BC9E71 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292 intact-crc:3E209D0DF4E0E071|rigid:48+tHpPivWNz+Dl9rxKAco/A0rI false mutation disrupting interaction:79-79|his tag:c-c|mutation increasing interaction:33-33 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12449 uniprotkb:P02829 intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863943 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:06DF6B40EB5050BE crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E4AB48F98353EDA7|rigid:JXPgQTz4kG+0/FTrocQ0RT+GLfw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06101 uniprotkb:P02829 intact:EBI-4266|ensemblfungi:YDR168W|uniprotkb:Q04132|uniprotkb:D6VSE8 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cdc37_yeast(display_long)|uniprotkb:SMO1(gene name synonym)|uniprotkb:YDR168W(locus name)|uniprotkb:YD9489.03(orf name)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division control protein 37(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863948 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010452.1|sgd:S000002575|ensemblfungi:YDR168W(gene)|ensemblfungi:YDR168W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030474"(spindle pole body duplication)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-SCE-114608|dip:DIP-2379N|mint:P06101 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:0DF0C923158A2526 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:UcyBqWm9JfONgRClm+Mrm2QbhUU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D80596DB6FF02F6A|rigid:lF7fL9pXtAr/+8vVL2Yry4Hi0JM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33313 uniprotkb:P02829 intact:EBI-4806|uniprotkb:Q02125|uniprotkb:D6VQF0|ensemblfungi:YBR155W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cns1_yeast(display_long)|uniprotkb:CNS1(gene name)|psi-mi:CNS1(display_short)|uniprotkb:YBR155W(locus name)|uniprotkb:YBR1205(orf name)|uniprotkb:Cyclophilin seven suppressor 1(gene name synonym)|uniprotkb:STI1 stress-inducible protein homolog(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863953 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009713.1|sgd:S000000359|dip:DIP-1271N|mint:P33313|ensemblfungi:YBR155W(gene)|ensemblfungi:YBR155W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044059|rcsb pdb:6HFM|rcsb pdb:6HFT ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:742F8254DFDB02A6 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:3vEtWsrh/ufn1qHwPkr6Iz+6qCs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7302122EBCF39F50|rigid:MDptorukKzZlJ7r+wS+0Udo0EsA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28707 uniprotkb:P02829 intact:EBI-26838|uniprotkb:D6VXH2|ensemblfungi:YKL117W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sba1_yeast(display_long)|uniprotkb:YKL518(orf name)|uniprotkb:YKL117W(locus name)|uniprotkb:SBA1(gene name)|psi-mi:SBA1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863958 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012805.1|sgd:S000001600|mint:P28707|dip:DIP-2311N|ensemblfungi:YKL117W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051972"(regulation of telomerase activity)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|rcsb pdb:2CG9|reactome:R-SCE-2162123|reactome:R-SCE-3371511|ensemblfungi:YKL117W(gene) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:C51CDE30BF2FA945 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:hwQEjV3B0/hBXv4hCsRrWTaFRBY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:FE0A23A6C0AA57C1|rigid:n+fx9RKJslfvASS0fdWZLWrNfTQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15705 uniprotkb:P02829 intact:EBI-18418|uniprotkb:D6W293|ensemblfungi:YOR027W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sti1_yeast(display_long)|uniprotkb:STI1(gene name)|psi-mi:STI1(display_short)|uniprotkb:OR26.17(orf name)|uniprotkb:YOR027W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863963 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014670.1|sgd:S000005553|ensemblfungi:YOR027W(gene)|ensemblfungi:YOR027W_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008104"(protein localization)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|rcsb pdb:2LLV|rcsb pdb:2LLW|rcsb pdb:3UPV|rcsb pdb:3UQ3|reactome:R-SCE-3371497|reactome:R-SCE-9696273|dip:DIP-2329N|mint:P15705 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:CF8A85C2BBD3C44C crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:+w2ibiXXPwvtcC3RxknGi0ELvvE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BB1E703E09D2ADD0|rigid:F9Ycrco6xgCMLu5p0ywm4wiQ6RI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51534 uniprotkb:P02829 intact:EBI-17086|ensemblfungi:YOR035C|uniprotkb:D6W2A2 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:she4_yeast(display_long)|uniprotkb:OR26.26(orf name)|uniprotkb:YOR035C(locus name)|uniprotkb:SHE4(gene name)|psi-mi:SHE4(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863968 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014678.1|sgd:S000005561|ensemblfungi:YOR035C(gene)|ensemblfungi:YOR035C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0017022"(myosin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024660|rcsb pdb:3OPB|dip:DIP-4186N|mint:P51534 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:4A0E1C7D41939B44 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:aahihUKRvHF7B8fqhzg2XIO1tpc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:1D8F5823A43EC4AD|rigid:adj2gyPDnoeQh4dTa2zN2n9kRKE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32589 uniprotkb:P02829 intact:EBI-8648|uniprotkb:D6W3R1|ensemblfungi:YPL106C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hsp7f_yeast(display_long)|uniprotkb:SSE1(gene name)|psi-mi:SSE1(display_short)|uniprotkb:MSI3(gene name synonym)|uniprotkb:YPL106C(locus name)|uniprotkb:LPG3C(orf name)|uniprotkb:Chaperone protein MSI3(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863973 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015219.1|sgd:S000006027|mint:P32589|dip:DIP-6645N|ensemblfungi:YPL106C(gene)|ensemblfungi:YPL106C_mRNA(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0006914"(autophagy)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:2QXL|rcsb pdb:3C7N|rcsb pdb:3D2E|rcsb pdb:3D2F ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6558259111B0BC38 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:16yTg05haoflKGNZTW4EqC7FSs0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:EA52AF31E6E96A9D|rigid:sw/BhKn2xkRGT4b4Zrpa8EoTC8Y false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25638 uniprotkb:P02829 intact:EBI-21956|uniprotkb:D6VR65|ensemblfungi:YCR060W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tah1_yeast(display_long)|uniprotkb:YCR60W(orf name)|uniprotkb:YCR060W(locus name)|uniprotkb:TAH1(gene name)|psi-mi:TAH1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863978 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009986.1|sgd:S000000656|mint:P25638|dip:DIP-5000N|ensemblfungi:YCR060W(gene)|ensemblfungi:YCR060W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051087"(chaperone binding)|go:"GO:0097255"(R2TP complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|rcsb pdb:2L6J|rcsb pdb:2LSU|rcsb pdb:2LSV|rcsb pdb:2MNJ|rcsb pdb:4CGQ|rcsb pdb:4CGU ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:3738DE6F227F803A crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:DXXWcBPtKzTtK2Hp7l4g0ukIZPQ559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E9D464222DD64E08|rigid:9ENGqIgahjzj2stsNbrA1ZzS+b4 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25491 uniprotkb:P02829 intact:EBI-10420|ensemblfungi:YNL064C|uniprotkb:D6W1B6 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mas5_yeast(display_long)|uniprotkb:YDJ1(gene name)|psi-mi:YDJ1(display_short)|uniprotkb:MAS5(gene name synonym)|uniprotkb:YNL064C(locus name)|uniprotkb:N2418(orf name)|uniprotkb:YNL2418C(orf name)|uniprotkb:Yeast dnaJ protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863983 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014335.1|sgd:S000005008|ensemblfungi:YNL064C_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|ensemblfungi:YNL064C(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0009408"(response to heat)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0042026"(protein refolding)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0072380"(TRC complex)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|rcsb pdb:1NLT|rcsb pdb:1XAO|rcsb pdb:5VSO|reactome:R-SCE-3371497|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|dip:DIP-2251N|mint:P25491 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:E4539F3618DD9CF2 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:oFw3ARy6McOdWBXpq0WK6si5GYw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7DE7316790824999|rigid:1uodejK/INCbqFGkyRwKjliZNYE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39078 uniprotkb:P02829 intact:EBI-19054|uniprotkb:Q07561|uniprotkb:D6VRK5|ensemblfungi:YDL143W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tcpd_yeast(display_long)|uniprotkb:YDL143W(locus name)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:ANC2(gene name synonym)|uniprotkb:TCP4(gene name synonym)|uniprotkb:CCT-delta(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863988 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010138.1|sgd:S000002302|ensemblfungi:YDL143W(gene)|ensemblfungi:YDL143W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6753N|mint:P39078 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:F01146D76F4E850C crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:GCSpoIEgtQxu/8dbncxp/4AXEls559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A28DF2A02DAD5FCC|rigid:ArhN8gKtqTtyI942aQP8Xd90HM0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38910 uniprotkb:P02829 intact:EBI-4553|uniprotkb:E9P935|uniprotkb:D6W286|ensemblfungi:YOR020C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ch10_yeast(display_long)|uniprotkb:HSP10(gene name)|psi-mi:HSP10(display_short)|uniprotkb:CPN10(gene name synonym)|uniprotkb:YOR020C(locus name)|uniprotkb:OR26.10(orf name)|uniprotkb:10 kDa chaperonin(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863993 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014663.1|sgd:S000005546|dip:DIP-1483N|mint:P38910|ensemblfungi:YOR020C(gene)|ensemblfungi:YOR020C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0042026"(protein refolding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR011032(GroES-like)|interpro:IPR018369|interpro:IPR020818|interpro:IPR037124 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:0453269D502C05E8 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:GVzaabkhuDg0Vb8Bdt6eXKMBE6Y559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6149B886B4441891|rigid:37xnDaTyD05PXZS4RrWfayVZQ20 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12329 uniprotkb:P02829 intact:EBI-8571|uniprotkb:D6VSF3|ensemblfungi:YDR171W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hsp42_yeast(display_long)|uniprotkb:HSP42(gene name)|psi-mi:HSP42(display_short)|uniprotkb:YDR171W(locus name)|uniprotkb:YD9395.04(orf name)|uniprotkb:42 kDa heat shock protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863998 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010456.1|sgd:S000002578|mint:Q12329|dip:DIP-2515N|ensemblfungi:YDR171W(gene)|ensemblfungi:YDR171W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0009408"(response to heat)|go:"GO:0009651"(response to salt stress)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043621"(protein self-association)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR031107 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:DF353A76493E3CE6 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:izvrv04fA3zcBqTeUeHD/erKGf4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:3DAC6AFEC3B4F8BA|rigid:F3q7C4D7ZTTW/OibfZ2P87tMEn0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19882 uniprotkb:P02829 intact:EBI-8586|uniprotkb:D6VYQ6|ensemblfungi:YLR259C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hsp60_yeast(display_long)|uniprotkb:HSP60(gene name)|psi-mi:HSP60(display_short)|uniprotkb:MIF4(gene name synonym)|uniprotkb:YLR259C(locus name)|uniprotkb:L8479.10(orf name)|uniprotkb:Stimulator factor I 66 kDa component(gene name synonym)|uniprotkb:P66(gene name synonym)|uniprotkb:CPN60(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864003 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013360.1|sgd:S000004249|mint:P19882|dip:DIP-7648N|ensemblfungi:YLR259C(gene)|ensemblfungi:YLR259C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051604"(protein maturation)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|reactome:R-SCE-1268020 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:279DC3AF5A2B0A3E crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:DoMJw4ScT3htVDJn+ZJD5fIlSOA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:CAADD525E8ABD743|rigid:ySHPQ1XchP22fBXTN1RVKjGCHbU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60010 uniprotkb:P02829 intact:EBI-2169|uniprotkb:P02579|uniprotkb:Q9P3X6|uniprotkb:Q9P3X7|uniprotkb:D6VTJ1|ensemblfungi:YFL039C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:act_yeast(display_long)|uniprotkb:ACT1(gene name)|psi-mi:ACT1(display_short)|uniprotkb:ABY1(gene name synonym)|uniprotkb:END7(gene name synonym)|uniprotkb:YFL039C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864008 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116614.1|sgd:S000001855|dip:DIP-310N|mint:P60010|ensemblfungi:YFL039C(gene)|ensemblfungi:YFL039C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005884"(actin filament)|go:"GO:0006281"(DNA repair)|go:"GO:0006897"(endocytosis)|go:"GO:0009306"(protein secretion)|go:"GO:0016573"(histone acetylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1902404"(mitotic actomyosin contractile ring contraction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:5NBL|rcsb pdb:5NBM|rcsb pdb:5NBN|rcsb pdb:5Y81|reactome:R-SCE-114608|reactome:R-SCE-190873|reactome:R-SCE-196025|reactome:R-SCE-2029482|reactome:R-SCE-5626467|reactome:R-SCE-5663213|reactome:R-SCE-8856828|reactome:R-SCE-8980692|reactome:R-SCE-9013026 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:87AC19B0B0BC9E71 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yfgwiWq/Y0HviACqgjjUugpEKLw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:57ED471A9B40C2B1|rigid:48+tHpPivWNz+Dl9rxKAco/A0rI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17536 uniprotkb:P02829 intact:EBI-19408|uniprotkb:D6W1A0|uniprotkb:Q45TY1|ensemblfungi:YNL079C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tpm1_yeast(display_long)|uniprotkb:N2332(orf name)|uniprotkb:YNL079C(locus name)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864013 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014320.1|sgd:S000005023|ensemblfungi:YNL079C(gene)|ensemblfungi:YNL079C_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000142"(cellular bud neck contractile ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003786"(actin lateral binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0006887"(exocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030447"(filamentous growth)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR000533(Tropomyosin)|dip:DIP-2992N|mint:P17536 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:UQPHVXtw3GAqHCzMqScDAmag+J0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:89436DEEB19A9F0A|rigid:+wsSxSMOL/zItLiX1WzEx5P6YQA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32468 uniprotkb:P02829 intact:EBI-4182|uniprotkb:D3DL57|ensemblfungi:YHR107C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cdc12_yeast(display_long)|uniprotkb:CDC12(gene name)|psi-mi:CDC12(display_short)|uniprotkb:CLA10(gene name synonym)|uniprotkb:PSL7(gene name synonym)|uniprotkb:YHR107C(locus name)|uniprotkb:Septin(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864018 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011975.1|sgd:S000001149|dip:DIP-853N|mint:P32468|ensemblfungi:YHR107C(gene)|ensemblfungi:YHR107C_mRNA(transcript)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0005940"(septin ring)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032160"(septin filament array)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A72DC393A6DBF924 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:RX1ddBeZj4BZ89IPrf0ZQdAX7AA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:73A2004768D0D561|rigid:ex/OipvDE7zPu+LqKcUOz+OgFuE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15442 uniprotkb:P02829 intact:EBI-330|uniprotkb:D6VSR3|ensemblfungi:YDR283C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gcn2_yeast(display_long)|uniprotkb:GCN2(gene name)|psi-mi:GCN2(display_short)|uniprotkb:AAS1(gene name synonym)|uniprotkb:General control non-derepressible protein 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase GCN2(gene name synonym)|uniprotkb:YDR283C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864023 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002691|refseq:NP_010569.3|dip:DIP-2346N|ensemblfungi:YDR283C(gene)|ensemblfungi:YDR283C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|mint:P15442|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043621"(protein self-association)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071232"(cellular response to histidine)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0072755"(cellular response to benomyl)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990451"(cellular stress response to acidic pH)|interpro:IPR000719(Protein kinase, core)|interpro:IPR006575(RWD)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR016255(Serine/threonine-protein kinase, GCN2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024435|interpro:IPR036621|interpro:IPR041715|rcsb pdb:1ZXE|rcsb pdb:1ZY4|rcsb pdb:1ZY5|rcsb pdb:1ZYC|rcsb pdb:1ZYD|rcsb pdb:2YZ0|rcsb pdb:4OTM ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:1F56E4B046D52325 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:d8fcrr70iKA6pK9Z4yqMQsPTAWI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:800F72FFA2BC5C54|rigid:VuGAA5apAoGFTjQJ4PxCa7dbQcY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32485 uniprotkb:P02829 intact:EBI-8437|uniprotkb:Q06232|uniprotkb:Q12294|uniprotkb:D6VYB1|ensemblfungi:YLR113W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hog1_yeast(display_long)|uniprotkb:HOG1(gene name)|psi-mi:HOG1(display_short)|uniprotkb:SSK3(gene name synonym)|uniprotkb:YLR113W(locus name)|uniprotkb:L2931(orf name)|uniprotkb:L9354.2(orf name)|uniprotkb:High osmolarity glycerol response protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864028 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013214.1|sgd:S000004103|dip:DIP-1558N|mint:P32485|ensemblfungi:YLR113W_mRNA(transcript)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038783|reactome:R-SCE-168638|reactome:R-SCE-193648|reactome:R-SCE-198753|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-418592|reactome:R-SCE-432142|reactome:R-SCE-450321|reactome:R-SCE-450341|reactome:R-SCE-525793|reactome:R-SCE-6798695|reactome:R-SCE-9007892|ensemblfungi:YLR113W(gene) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:D95A20242587CE06 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Re8xLAJEvP2Fjr0lOGtLB6ANybM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:F7F01F4F42367A8F|rigid:T/d7ngrwJxa4C2f8cqdmaJl3Nkg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14681 uniprotkb:P02829 intact:EBI-9945|uniprotkb:Q45U43|uniprotkb:D6VUH8|ensemblfungi:YGR040W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:kss1_yeast(display_long)|uniprotkb:KSS1(gene name)|psi-mi:KSS1(display_short)|uniprotkb:Kinase suppressor of SST2(gene name synonym)|uniprotkb:YGR040W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864033 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003272|ensemblfungi:YGR040W(gene)|ensemblfungi:YGR040W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042597"(periplasmic space)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-111995|reactome:R-SCE-112411|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-375165|reactome:R-SCE-437239|reactome:R-SCE-5687128|reactome:R-SCE-6798695|reactome:R-SCE-881907|reactome:R-SCE-9634635|refseq:NP_011554.3|reactome:R-SCE-112409|reactome:R-SCE-3371453|reactome:R-SCE-445144|reactome:R-SCE-5673001|reactome:R-SCE-5674135|reactome:R-SCE-5674499|dip:DIP-60N|reactome:R-SCE-170968|reactome:R-SCE-450341 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:5FA42161B5FD51B5 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:xE1y1jku+iWy4xzv9wUCul1AFZs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4CDB6429D25EF7EA|rigid:BbIX90amTTJZ1z94MhQytVS2Uys false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00772 uniprotkb:P02829 intact:EBI-17372|uniprotkb:D3DKX7|ensemblfungi:YHR030C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:slt2_yeast(display_long)|uniprotkb:YHR030C(locus name)|uniprotkb:SLT2(gene name)|psi-mi:SLT2(display_short)|uniprotkb:MPK1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864038 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011895.1|sgd:S000001072|ensemblfungi:YHR030C(gene)|ensemblfungi:YHR030C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043332"(mating projection tip)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0060256"(regulation of flocculation)|go:"GO:0090364"(regulation of proteasome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-198753|reactome:R-SCE-202670|reactome:R-SCE-2559582|reactome:R-SCE-881907|dip:DIP-1448N|reactome:R-SCE-198765|reactome:R-SCE-4086398 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:559A3E0D3EBDE5F9 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:1dJe7ldR8bi2mbvPugrkZAHrrVw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:97732638A6E08D53|rigid:WI6ozuzkkSWp8eeV32YiFjrmtfI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23561 uniprotkb:P02829 intact:EBI-18259|uniprotkb:D6VZ00|ensemblfungi:YLR362W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ste11_yeast(display_long)|uniprotkb:STE11(gene name)|psi-mi:STE11(display_short)|uniprotkb:L8039.10(orf name)|uniprotkb:YLR362W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864043 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013466.1|sgd:S000004354|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035405"(histone-threonine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029458|rcsb pdb:1OW5|rcsb pdb:1X9X|reactome:R-SCE-2559580|ensemblfungi:YLR362W(gene)|ensemblfungi:YLR362W_mRNA(transcript)|go:"GO:0000161"(osmosensory signaling MAPK cascade)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|dip:DIP-861N|mint:P23561 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:E9E0DF27114EEEEF crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:KhdnSv61wKSQuH5bBkQS9yVxLns559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D7B42A7507F69A46|rigid:04rksDuQCUZ0III40FLuzCB43Gw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23291 uniprotkb:P02829 intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864048 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:77344717818C2D17 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D349AEEF81D32768|rigid:axW8K8EQFVUllA976FeCNeQSmSw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0CS82 uniprotkb:P02829 intact:EBI-5419|uniprotkb:Q6BD21|uniprotkb:Q06574|intact:EBI-3670926|uniprotkb:P12351|uniprotkb:P0CE42 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hap1_yeasx(display_long)|uniprotkb:HAP1(gene name)|psi-mi:HAP1(display_short)|uniprotkb:CYP1(gene name synonym)|uniprotkb:Heme activator protein 1(gene name synonym)|uniprotkb:CYP1 activatory protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864053 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|mint:P0CS82|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:1HWT|rcsb pdb:1PYC|rcsb pdb:1QP9|rcsb pdb:2HAP ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:4V/piX51z+5Q4cOO+WEiZMQ3j604932 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:32FEFB4010C42E2E|rigid:s6Tp/Wd1Im+rfhql3XruU96xnIQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P33200 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-13025|uniprotkb:D6VPZ5|uniprotkb:E9P920|ensemblfungi:YBL005W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:pdr3_yeast(display_long)|uniprotkb:PDR3(gene name)|psi-mi:PDR3(display_short)|uniprotkb:YBL005W(locus name)|uniprotkb:YBL0323(orf name)|uniprotkb:Pleiotropic drug resistance protein 3(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864058 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_009548.1|sgd:S000000101|mint:P33200|dip:DIP-793N|ensemblfungi:YBL005W(gene)|ensemblfungi:YBL005W_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001040"(positive regulation of cellular response to drug)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864 - crc64:D7C35676D668FB63 - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:m4wOGEHFKnd9tAdkIz88GjmRUCM559292 intact-crc:D0D84CB309CB0A3F|rigid:+ykfNaWhgvy3zW4XIQR25RmS5Ys false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36023 uniprotkb:P02829 intact:EBI-26463|uniprotkb:D6VXC5|ensemblfungi:YKR064W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:oaf3_yeast(display_long)|uniprotkb:YKR064W(locus name)|uniprotkb:OAF3(gene name)|psi-mi:OAF3(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864063 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012990.1|sgd:S000001772|mint:P36023|dip:DIP-2792N|ensemblfungi:YKR064W(gene)|ensemblfungi:YKR064W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:89cEl73sfAGz/ZQY5c16xnIypIk559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:34B5BC245A1349CF|rigid:t2VBBTqfg0YPxW6bAz9PJnWOpKg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47035 uniprotkb:P02829 intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864068 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:80EDF9A8065EB5A2 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9292CD50C92F026D|rigid:+fNRI8eaTNVTupEwee/5dCAy/bU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38429 uniprotkb:P02829 intact:EBI-27570|uniprotkb:Q03501|uniprotkb:D6W089|ensemblfungi:YMR263W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sap30_yeast(display_long)|uniprotkb:YM8156.05(orf name)|uniprotkb:YMR263W(locus name)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864073 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013990.1|sgd:S000004876|dip:DIP-3846N|mint:P38429|ensemblfungi:YMR263W(gene)|ensemblfungi:YMR263W_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR024145|interpro:IPR025718|interpro:IPR038291|reactome:R-SCE-3214815 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:37Rq1e4YnQ0iYtV3Ax1RjddetpM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:483C9D8C37202F30|rigid:afwerw2SuAe5ht/JK32kmhEYvmg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06700 uniprotkb:P02829 intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864078 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:52E6937533654586 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:CDA07B26EE08E12C|rigid:enDKVkL5CPgb2XXqzyaEC0DDppA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12206 uniprotkb:P02829 intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864083 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:4A8F5F879B88AA94 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6F60C43959F7CCB6|rigid:uniCUKxiWvGpIn91S27sZm+2wmU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47123 uniprotkb:P02829 intact:EBI-11145|ensemblfungi:YJR074W|uniprotkb:D6VWP4 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mog1_yeast(display_long)|uniprotkb:MOG1(gene name)|psi-mi:MOG1(display_short)|uniprotkb:YJR074W(locus name)|uniprotkb:J1827(orf name)|uniprotkb:Multicopy suppressor of GSP1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864088 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR074W(gene)|ensemblfungi:YJR074W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR007681(Ran-interacting Mog1 protein)|interpro:IPR016123(Mog1/PsbP, alpha/beta/alpha sandwich)|rcsb pdb:1EQ6|rcsb pdb:1JHS|refseq:NP_012608.1|sgd:S000003835|mint:P47123|dip:DIP-1356N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:980156FF01A1542D crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K/b/z/ls5JWD2Cfp16rgCi0AtvU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B30414630BE9505A|rigid:HPLzhTJsj0dQkrDuawRyhPwhBzE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46970 uniprotkb:P02829 intact:EBI-12084|uniprotkb:D6VWV0|ensemblfungi:YJR132W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:nmd5_yeast(display_long)|uniprotkb:NMD5(gene name)|psi-mi:NMD5(display_short)|uniprotkb:YJR132W(locus name)|uniprotkb:J2112(orf name)|uniprotkb:KAP119(gene name synonym)|uniprotkb:Karyopherin-119(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864093 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR132W(gene)|ensemblfungi:YJR132W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_012666.2|sgd:S000003893|dip:DIP-2326N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:90312C1AAE515949 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yWSDW0KbIHHCaXNo7DoXqRIvdeU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:72FDC0B41295BC2A|rigid:6/MvsNY1n1ROk5ERrILhst4qzFs false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48837 uniprotkb:P02829 intact:EBI-12324|ensemblfungi:YGR119C|uniprotkb:D6VUQ0 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:nup57_yeast(display_long)|uniprotkb:NUP57(gene name)|psi-mi:NUP57(display_short)|uniprotkb:YGR119C(locus name)|uniprotkb:G6320(orf name)|uniprotkb:Nuclear pore protein NUP57(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864098 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR119C(gene)|ensemblfungi:YGR119C_mRNA(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025574|interpro:IPR025712|refseq:NP_011634.1|sgd:S000003351|mint:P48837|dip:DIP-866N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ultDTflWHx7n/y2FrlWFf+lBKmw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:CE4B00F55E01FF4B|rigid:XkYVDEPU6tIRRtkI5/nYgz/94z0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01119 uniprotkb:P02829 intact:EBI-14830|uniprotkb:D6W2G2|ensemblfungi:YOR101W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ras1_yeast(display_long)|uniprotkb:YOR3205W(orf name)|uniprotkb:YOR101W(locus name)|uniprotkb:RAS1(gene name)|psi-mi:RAS1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864103 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014744.1|sgd:S000005627|ensemblfungi:YOR101W(gene)|ensemblfungi:YOR101W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019003"(GDP binding)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SCE-9696273|dip:DIP-1041N|mint:P01119 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A70D720EB67E2F91 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ly4o9gZAABZELZx3mhTPZeAqsag559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:AEE9803E0EEE98CD|rigid:TIvW0iAHdZOV4vl9/9xpS9crMts false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32939 uniprotkb:P02829 intact:EBI-29509|uniprotkb:D6VZH4|ensemblfungi:YML001W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ypt7_yeast(display_long)|uniprotkb:YPT7(gene name)|psi-mi:YPT7(display_short)|uniprotkb:VAM4(gene name synonym)|uniprotkb:Vacuolar morphology protein 4(gene name synonym)|uniprotkb:YM8270.02(orf name)|uniprotkb:YML001W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864108 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013713.1|sgd:S000004460|dip:DIP-1735N|mint:P32939|ensemblfungi:YML001W(gene)|ensemblfungi:YML001W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1KY2|rcsb pdb:1KY3|rcsb pdb:4PHF|rcsb pdb:4PHG|rcsb pdb:4PHH|reactome:R-SCE-6798695|reactome:R-SCE-8854214|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-9013405|reactome:R-SCE-9013406 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:0E2B72BDA7F7CEE5 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ZR2uZTxqTXnSamelDJbMoEI2af8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:09990D67F98AEED1|rigid:XB7noToIVKJ3U5Ncyh+PEwpaVCI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38555 uniprotkb:P02829 intact:EBI-29379|uniprotkb:D3DLT0|ensemblfungi:YER031C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ypt31_yeast(display_long)|uniprotkb:Rab GTPase YPT31(gene name synonym)|uniprotkb:YPT31(gene name)|psi-mi:YPT31(display_short)|uniprotkb:YPT8(gene name synonym)|uniprotkb:YER031C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864113 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010948.1|sgd:S000000833|dip:DIP-2022N|mint:P38555|ensemblfungi:YER031C(gene)|ensemblfungi:YER031C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3CPJ|reactome:R-SCE-8873719 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:EC274E5873138D78 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:z5YqRrgMniz5YCUrviuNEt5mZMo559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:8ECA9F862E4158CC|rigid:KWpEK/c97b/VrguKcLJE17eKmlw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36019 uniprotkb:P02829 intact:EBI-29415|uniprotkb:Q45TZ5|uniprotkb:D6W187|ensemblfungi:YNL093W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ypt53_yeast(display_long)|uniprotkb:YPT53(gene name)|psi-mi:YPT53(display_short)|uniprotkb:N2223(orf name)|uniprotkb:YNL093W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864118 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005037|refseq:NP_014306.3|dip:DIP-2025N|ensemblfungi:YNL093W(gene)|ensemblfungi:YNL093W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:ABA1D926D1EE9F68 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:2IDdF9ESvaxekyjmAzuRL9vMYJ8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A9D5F94A2FC392C3|rigid:yT8ItxDS9S4tbzR6RLMxxz9WiPw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25385 uniprotkb:P02829 intact:EBI-3735|uniprotkb:D6VY78|ensemblfungi:YLR078C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bos1_yeast(display_long)|uniprotkb:BOS1(gene name)|psi-mi:BOS1(display_short)|uniprotkb:YLR078C(locus name)|uniprotkb:L9449.9(orf name)|uniprotkb:Bet one suppressor 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864123 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013179.1|sgd:S000004068|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|dip:DIP-2020N|ensemblfungi:YLR078C(gene)|ensemblfungi:YLR078C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR027027 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Rwf+Olm3mXTGhh/KZUgtVel+wzc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A7EE3733FEE968DF|rigid:CqZT1cB7ueCmyztqwc5FLH6Vj14 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39727 uniprotkb:P02829 intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864128 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:FB7BC171B88BB5EA crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:64A4C2676F645685|rigid:Ygv5if5GRxP7JK9QkoStZh8vDB0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32854 uniprotkb:P02829 intact:EBI-13098|ensemblfungi:YOR036W|uniprotkb:D6W2A3 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pep12_yeast(display_long)|uniprotkb:PEP12(gene name)|psi-mi:PEP12(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 13(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 12(gene name synonym)|uniprotkb:VPS6(gene name synonym)|uniprotkb:VPT13(gene name synonym)|uniprotkb:OR26.29(orf name)|uniprotkb:YOR036W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864133 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR036W(gene)|ensemblfungi:YOR036W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|refseq:NP_014679.1|sgd:S000005562|mint:P32854|dip:DIP-2021N|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-SCE-204005 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:D9F5711339DA1CDA crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:RAEwrvQSX1rO6JTK4hInPnMkYKU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:1DD308F58DC3C154|rigid:8PEf4UUzbLFJsY9/jYtJMJQFVPM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08144 uniprotkb:P02829 intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864138 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:CEBD6FE11278B1F0 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:C162101AB3DEB70C|rigid:S1hVDRIsWkvEa1dxq64y5aw8lIA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38962 uniprotkb:P02829 intact:EBI-22146|uniprotkb:D6VS71|ensemblfungi:YDR084C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tvp23_yeast(display_long)|uniprotkb:TLG2 compartment vesicle protein of 23 kDa(gene name synonym)|uniprotkb:TVP23(gene name)|psi-mi:TVP23(display_short)|uniprotkb:YDR084C(locus name)|uniprotkb:D4466(orf name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864143 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010369.3|sgd:S000002491|dip:DIP-1822N|mint:P38962|ensemblfungi:YDR084C(gene)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR008564(Protein of unknown function DUF846, eukaryotic)|ensemblfungi:YDR084C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:516BBCBB80F88BCF crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:IgQg+TK8Pqo6rIEptKD4JU3g0YQ559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:0E3129E1C06356A5|rigid:Kn9/ZbIXlPDJE8HPz7TjbtMnYnU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47111 uniprotkb:P02829 intact:EBI-25497|uniprotkb:D6VWL5|ensemblfungi:YJR044C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:vps55_yeast(display_long)|uniprotkb:J1637(orf name)|uniprotkb:YJR044C(locus name)|uniprotkb:VPS55(gene name)|psi-mi:VPS55(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864148 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003805|refseq:NP_012578.3|dip:DIP-7667N|mint:P47111|ensemblfungi:YJR044C(gene)|ensemblfungi:YJR044C_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034424"(Vps55/Vps68 complex)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR007262(Vacuolar protein sorting 55) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:1F207E62F093FC6D crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:J23lc6VW+GZsH/Tu+ukXF5QauPg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2ED60D42585D2C3D|rigid:LaVpTNqRkFXMu6xwg85Vs0zW5X0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53108 uniprotkb:P02829 intact:EBI-24051|uniprotkb:D6VTZ0|ensemblfungi:YGL161C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yip5_yeast(display_long)|uniprotkb:YGL161C(locus name)|uniprotkb:G1832(orf name)|uniprotkb:YIP5(gene name)|psi-mi:YIP5(display_short)|uniprotkb:YPT-interacting protein 5(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864153 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003129|refseq:NP_011354.3|dip:DIP-1728N|mint:P53108|ensemblfungi:YGL161C(gene)|ensemblfungi:YGL161C_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|interpro:IPR006977(Yip1 domain)|interpro:IPR039765 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:2F1477F616FCD602 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Hr7iRG1PgifzQMgnCRBCY6uk1fg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:56B02175E141E535|rigid:yybOWT8uFHtuUKLN/t6AYYAuSlk false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38090 uniprotkb:P02829 intact:EBI-2362|uniprotkb:D6VQC9|ensemblfungi:YBR132C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:agp2_yeast(display_long)|uniprotkb:AGP2(gene name)|psi-mi:AGP2(display_short)|uniprotkb:YBR1007(orf name)|uniprotkb:YBR132C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864158 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009690.1|sgd:S000000336|dip:DIP-8141N|mint:P38090|ensemblfungi:YBR132C(gene)|ensemblfungi:YBR132C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902269"(positive regulation of polyamine transmembrane transport)|go:"GO:1902274"("positive regulation of (R)-carnitine transmembrane transport")|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:SQ0XmZP6PWuNCjgiQs2JkcI0RzA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:1B1622AC66A4BE9E|rigid:fObiyXWnMM0AZET1v6Tf+HD4sgk false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53048 uniprotkb:P02829 intact:EBI-2377|uniprotkb:D6VV66|ensemblfungi:YGR289C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mal11_yeast(display_long)|uniprotkb:MAL11(gene name)|psi-mi:MAL11(display_short)|uniprotkb:AGT1(gene name synonym)|uniprotkb:MAL1T(gene name synonym)|uniprotkb:Maltose permease MAL11(gene name synonym)|uniprotkb:Maltose transport protein MAL11(gene name synonym)|uniprotkb:MTP1(gene name synonym)|uniprotkb:YGR289C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864163 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011805.3|sgd:S000003521|dip:DIP-5567N|ensemblfungi:YGR289C(gene)|ensemblfungi:YGR289C_mRNA(transcript)|go:"GO:0000017"(alpha-glucoside transport)|go:"GO:0000023"(maltose metabolic process)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005352"("alpha-glucoside:proton symporter activity")|go:"GO:0005364"("maltose:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015574"(trehalose transmembrane transporter activity)|go:"GO:0015768"(maltose transport)|go:"GO:0015771"(trehalose transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046352"(disaccharide catabolic process)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ZdXGT7AjyORpGm8QCZkjrw2/Mgs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6150D325D75B33AA|rigid:8UQ6rNXDOWUchZG3VPyTMmzCofo false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06497 uniprotkb:P02829 intact:EBI-36879|uniprotkb:D6W4C5|ensemblfungi:YPR128C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ant1_yeast(display_long)|uniprotkb:ANT1(gene name)|psi-mi:ANT1(display_short)|uniprotkb:YPR128C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864168 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015453.1|sgd:S000006332|mint:Q06497|dip:DIP-8825N|ensemblfungi:YPR128C(gene)|ensemblfungi:YPR128C_mRNA(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0015217"(ADP transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0015867"(ATP transport)|interpro:IPR018108|interpro:IPR023395 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:DH4ti6Peo5vXKjBQdHUMnb87XCs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:0D5528B9EC9D9CD9|rigid:fpTmGCFC/34Ya6KZSJNM+W1bzck false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53943 uniprotkb:P02829 intact:EBI-28741|uniprotkb:Q6B1F8|uniprotkb:D6W1B5|ensemblfungi:YNL065W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:aqr1_yeast(display_long)|uniprotkb:N2417(orf name)|uniprotkb:AQR1(gene name)|psi-mi:AQR1(display_short)|uniprotkb:YNL2417W(orf name)|uniprotkb:YNL065W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864173 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005009|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR005829(Sugar transporter, conserved site)|refseq:NP_014334.3|mint:P53943|interpro:IPR036259|ensemblfungi:YNL065W(gene)|ensemblfungi:YNL065W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032973"(amino acid export across plasma membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:WBENC6wtGRBBIg+ylZSFBqlxnmY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A0D7975641ACEB5E|rigid:my/2/TKjIKctbU3i1PXC8zlwfIo false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40074 uniprotkb:P02829 intact:EBI-22666|uniprotkb:D3DM25|ensemblfungi:YER119C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:avt6_yeast(display_long)|uniprotkb:YER119C(locus name)|uniprotkb:AVT6(gene name)|psi-mi:AVT6(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864178 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011044.1|sgd:S000000921|dip:DIP-4489N|ensemblfungi:YER119C(gene)|ensemblfungi:YER119C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005290"(L-histidine transmembrane transporter activity)|go:"GO:0005302"(L-tyrosine transmembrane transporter activity)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032974"(amino acid transmembrane export from vacuole)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|interpro:IPR013057(Amino acid transporter, transmembrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:KSuV+ucakPCtl1xQLMI6W54S7r0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:64B7CFC96804196D|rigid:dV2hz8RQXX+XYqLle3KrZbAgOPY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41815 uniprotkb:P02829 intact:EBI-3419|uniprotkb:D6VS34|ensemblfungi:YDR046C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bap3_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 3(gene name synonym)|uniprotkb:BAP3(gene name)|psi-mi:BAP3(display_short)|uniprotkb:PAP1(gene name synonym)|uniprotkb:YDR046C(locus name)|uniprotkb:YD9609.02C(orf name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864183 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002453|refseq:NP_010331.3|dip:DIP-7900N|ensemblfungi:YDR046C(gene)|ensemblfungi:YDR046C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ocGGmM6MA0vV6pISdzIpLtsuy34559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:389DB23F22CC897A|rigid:QbyV16h+1GFKm2adrW2hIFRpMrc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08280 uniprotkb:P02829 intact:EBI-35858|uniprotkb:Q6B229|uniprotkb:D6W1T2|ensemblfungi:YOL137W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bsc6_yeast(display_long)|uniprotkb:YOL137W(locus name)|uniprotkb:BSC6(gene name)|psi-mi:BSC6(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864188 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014504.1|sgd:S000005497|mint:Q08280|dip:DIP-4683N|ensemblfungi:YOL137W(gene)|ensemblfungi:YOL137W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:WVYZke8YJvNcS4D9bUnthAFdq3A559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:411990CD7AC39F18|rigid:3dUczkjyS2joIH3Kc2imhty4RGo false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38356 uniprotkb:P02829 intact:EBI-3783|uniprotkb:D6VQT5|ensemblfungi:YBR290W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bsd2_yeast(display_long)|uniprotkb:BSD2(gene name)|psi-mi:BSD2(display_short)|uniprotkb:YBR290W(locus name)|uniprotkb:YBR2037(orf name)|uniprotkb:Bypass SOD defects protein 2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864193 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009849.1|sgd:S000000494|dip:DIP-7753N|mint:P38356|ensemblfungi:YBR290W(gene)|ensemblfungi:YBR290W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030001"(metal ion transport)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019325 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:PhPAghIkH6b6y74qLZH9EjoRd6U559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2F4351686620BF50|rigid:EpSyvhPRNwfrIWzKxD7sversL7Q false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04817 uniprotkb:P02829 intact:EBI-3993|uniprotkb:D3DLI7|ensemblfungi:YEL063C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:can1_yeast(display_long)|uniprotkb:CAN1(gene name)|psi-mi:CAN1(display_short)|uniprotkb:Canavanine resistance protein 1(gene name synonym)|uniprotkb:YEL063C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864198 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010851.1|sgd:S000000789|dip:DIP-4062N|ensemblfungi:YEL063C(gene)|ensemblfungi:YEL063C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015181"|go:"GO:0015802"(basic amino acid transport)|go:"GO:0015809"|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|go:"GO:0045121"(membrane raft)|go:"GO:0055085"(transmembrane transport)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:6r1g2EVjKacF9Ty+Xn+kF1wQiqY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:DCDE5E0C0D5A48F0|rigid:EZFoakRd0yWTeo4VEGz3Mp7k5M8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15365 uniprotkb:P02829 intact:EBI-5527|uniprotkb:D6VWX1|ensemblfungi:YJR152W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:dal5_yeast(display_long)|uniprotkb:DAL5(gene name)|psi-mi:DAL5(display_short)|uniprotkb:UREP1(gene name synonym)|uniprotkb:YJR152W(locus name)|uniprotkb:J2230(orf name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864203 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003913|refseq:NP_012686.3|dip:DIP-7873N|mint:P15365|ensemblfungi:YJR152W(gene)|ensemblfungi:YJR152W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015124"(allantoate transmembrane transporter activity)|go:"GO:0015719"(allantoate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0042938"(dipeptide transport)|go:"GO:0042939"(tripeptide transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Y2kCv3dK4Hjn9hJpK+WK5rp6VKU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9DC27C037BAF9598|rigid:H60DqH+51uCv3elIJKFFjG7G1qo false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53918 uniprotkb:P02829 intact:EBI-28895|uniprotkb:D6W158|ensemblfungi:YNL125C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:esbp6_yeast(display_long)|uniprotkb:YNL125C(locus name)|uniprotkb:N1882(orf name)|uniprotkb:N1223(orf name)|uniprotkb:ESBP6(gene name)|psi-mi:ESBP6(display_short)|uniprotkb:MCH3(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864208 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014274.1|sgd:S000005069|dip:DIP-4797N|reactome:R-SCE-352230|reactome:R-SCE-879518|ensemblfungi:YNL125C(gene)|ensemblfungi:YNL125C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071627"(integral component of fungal-type vacuolar membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A4CA35AE50A79E7A crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ukUEdtoMA5dxWWegNWudv8ov/c4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:345F67D4E4EA0FC5|rigid:f786x4ny/0yDxMZVyUtjVoD3nUM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31381 uniprotkb:P02829 intact:EBI-7145|uniprotkb:D6VPJ6|ensemblfungi:YAL022C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:fun26_yeast(display_long)|uniprotkb:FUN26(gene name)|psi-mi:FUN26(display_short)|uniprotkb:YAL022C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864213 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009380.1|sgd:S000000020|dip:DIP-5495N|mint:P31381|ensemblfungi:YAL022C(gene)|ensemblfungi:YAL022C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005337"(nucleoside transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015205"(nucleobase transmembrane transporter activity)|go:"GO:0015851"(nucleobase transport)|go:"GO:0015858"(nucleoside transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034257"(nicotinamide riboside transmembrane transporter activity)|go:"GO:0034258"(nicotinamide riboside transport)|go:"GO:0055085"(transmembrane transport)|interpro:IPR002259(Delayed-early response protein/equilibrative nucleoside transporter)|interpro:IPR034764|interpro:IPR036259|reactome:R-SCE-83936 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:p1R98fT22EaoJ8MdftJJHpQTRZA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D5DD66F49F8B0D70|rigid:l1M/O9N7O97E9Y7mmuXwXXSAKUY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32465 uniprotkb:P02829 intact:EBI-8759|ensemblfungi:YHR094C|uniprotkb:D3DL45 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hxt1_yeast(display_long)|uniprotkb:YHR094C(locus name)|uniprotkb:HXT1(gene name)|psi-mi:HXT1(display_short)|uniprotkb:HOR4(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864218 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR094C(gene)|ensemblfungi:YHR094C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015761"(mannose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011962.1|sgd:S000001136|mint:P32465|dip:DIP-5593N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:MgWRy3066aSsOcH1JJHkWwCZYWI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:F15CDBA6394AB552|rigid:kIItJDbdyTA9aoIH+WYbJKtd2yI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P02829 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864223 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6906721BAC1A5F87 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D6EB8976746E236D|rigid:QH2zlD1tHzUyHNHj2TXiTrOkVvc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43581 uniprotkb:P02829 intact:EBI-8750|ensemblfungi:YFL011W|uniprotkb:D6VTL8 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hxt10_yeast(display_long)|uniprotkb:YFL011W(locus name)|uniprotkb:HXT10(gene name)|psi-mi:HXT10(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864228 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL011W(gene)|ensemblfungi:YFL011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005354"(galactose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_116644.1|sgd:S000001883|dip:DIP-5424N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yIuSvTiYVBdOBjxBZTnJ9SYNbAs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A81B212F80FE30AF|rigid:sahqVeFPFo0mhIAcIOxMrbR9mZ8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53631 uniprotkb:P02829 intact:EBI-8851|ensemblfungi:YNR072W|uniprotkb:D6W1P7 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hxt17_yeast(display_long)|uniprotkb:N3615(orf name)|uniprotkb:YNR072W(locus name)|uniprotkb:HXT17(gene name)|psi-mi:HXT17(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864233 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNR072W(gene)|ensemblfungi:YNR072W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0015795"(sorbitol transport)|go:"GO:0015797"(mannitol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_014470.1|sgd:S000005355|dip:DIP-4810N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:r86lp6wqoeHwoC8EeO1zJ5veE1Y559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:AF13D0E3CD793D69|rigid:FViOaPy9cnbwkwY2/H1dyQBweDA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32487 uniprotkb:P02829 intact:EBI-10258|uniprotkb:D6W0S6|ensemblfungi:YNL268W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:lyp1_yeast(display_long)|uniprotkb:LYP1(gene name)|psi-mi:LYP1(display_short)|uniprotkb:N0790(orf name)|uniprotkb:YNL268W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864238 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|refseq:NP_014131.1|sgd:S000005212|ensemblfungi:YNL268W(gene)|ensemblfungi:YNL268W_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015802"(basic amino acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032126"(eisosome)|mint:P32487 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:54NWGujHb25P5sWLEHSOC6ytuG4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:43DC3C5C8BAF5355|rigid:nAxI637IXLPlaaBiXrMZ8vZQ9IY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47186 uniprotkb:P02829 intact:EBI-10454|intact:EBI-2072395|uniprotkb:Q07787|dip:DIP-5180N intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mph23_yeast(display_long)|uniprotkb:MPH3(gene name)|psi-mi:MPH3(display_short)|uniprotkb:YJR160C(locus name)|uniprotkb:MPH2(gene name)|psi-mi:MPH2(display_short)|uniprotkb:YDL247W(locus name)|uniprotkb:J2400(orf name)|uniprotkb:Maltose transport protein 2/3(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864243 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003921(MPH3)|go:"GO:0000023"(maltose metabolic process)|go:"GO:0055085"(transmembrane transport)|refseq:NP_012694.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0015151"(alpha-glucoside transmembrane transporter activity)|go:"GO:0000017"(alpha-glucoside transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005829(Sugar transporter, conserved site)|cygd:YDL247w|cygd:YJR160c|sgd:S000002406|ensembl:YJR160C|go:"GO:0005515"(protein binding)|refseq:NP_010034.1|interpro:IPR016196(MFS general substrate transporter)|uniprotkb:P47186(uniprot-removed-ac)|uniprotkb:P47186(uniprot-removed-ac) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:3IfKTnEBIagHyLeRKvhPvNSyg2A4932 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:C54EDF6220F86A8C|rigid:UhBkQiZKY4mHpepyBfr1CTZrt4U false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50276 uniprotkb:P02829 intact:EBI-11624|uniprotkb:Q45U31|ensemblfungi:YGR055W|uniprotkb:D6VUJ0 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mup1_yeast(display_long)|uniprotkb:MUP1(gene name)|psi-mi:MUP1(display_short)|uniprotkb:YGR055W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864248 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR055W(gene)|ensemblfungi:YGR055W_mRNA(transcript)|go:"GO:0000101"(sulfur amino acid transport)|go:"GO:0000102"(L-methionine secondary active transmembrane transporter activity)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015821"(methionine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042883"(cysteine transport)|go:"GO:0071944"(cell periphery)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-SCE-352230|refseq:NP_011569.1|sgd:S000003287|mint:P50276|dip:DIP-7914N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:GvSwcAx3mFOJv3SDLClDA4I1RXM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6E748DBE2898E8A7|rigid:W48fZw8711UoOBGndqrUX53B8Rc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38734 uniprotkb:P02829 intact:EBI-11630|ensemblfungi:YHL036W|uniprotkb:D3DKT2 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mup3_yeast(display_long)|uniprotkb:MUP3(gene name)|psi-mi:MUP3(display_short)|uniprotkb:YHL036W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864253 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHL036W(gene)|ensemblfungi:YHL036W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015191"(L-methionine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1903692"(methionine import across plasma membrane)|interpro:IPR002293(Amino acid/polyamine transporter I)|refseq:NP_011827.1|sgd:S000001028|dip:DIP-5572N|reactome:R-SCE-352230 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:FBACE5/pvW3GE2RhjsY7Uuhy03Y559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BDB1AE46DDC4AEC2|rigid:kD70JLWU7xQ0pq9j5Sh4rjLiXEI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46956 uniprotkb:P02829 intact:EBI-13337|uniprotkb:E9P8T7|ensemblfungi:YJL117W|uniprotkb:D6VW67 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pho86_yeast(display_long)|uniprotkb:PHO86(gene name)|psi-mi:PHO86(display_short)|uniprotkb:J0744(orf name)|uniprotkb:YJL117W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864258 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012418.1|sgd:S000003653|interpro:IPR024297|ensemblfungi:YJL117W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051082"(unfolded protein binding)|ensemblfungi:YJL117W(gene)|mint:P46956|dip:DIP-2769N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:1CB19C9184BF1C48 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:JITWReptfMoij1Uy6y1e3Oa6dAs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BFDD89A35BF75F6C|rigid:srX9JZx0Sm8P+jj+0ILhkyKBfVg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15380 uniprotkb:P02829 intact:EBI-14315|uniprotkb:D6W343|ensemblfungi:YOR348C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:put4_yeast(display_long)|uniprotkb:O6345(orf name)|uniprotkb:YOR348C(locus name)|uniprotkb:PUT4(gene name)|psi-mi:PUT4(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864263 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014993.1|sgd:S000005875|ensemblfungi:YOR348C(gene)|ensemblfungi:YOR348C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0015812"(gamma-aminobutyric acid transport)|go:"GO:0015824"(proline transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|dip:DIP-1541N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:YCZUq7RxZXUgRQF8n810UCEypvo559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:1920EF44772D9D1D|rigid:1f49VimjOBhNmgRmlqT2g89QsME false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12407 uniprotkb:P02829 intact:EBI-33162|uniprotkb:D6VRF5|ensemblfungi:YDL199C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yd199_yeast(display_long)|uniprotkb:D1209(orf name)|uniprotkb:YDL199C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864268 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010082.1|sgd:S000002358|mint:Q12407|dip:DIP-8956N|ensemblfungi:YDL199C(gene)|ensemblfungi:YDL199C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:s39vivUjIZIzcTO4OLM/PbrCjvM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7AC649C4D80F02F0|rigid:m6MEccCjDFbag8exF4+e0XWsvtw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40475 uniprotkb:P02829 intact:EBI-25197|uniprotkb:D6VVG7|ensemblfungi:YIL120W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:qdr1_yeast(display_long)|uniprotkb:YIL120W(locus name)|uniprotkb:QDR1(gene name)|psi-mi:QDR1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864273 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012146.1|sgd:S000001382|dip:DIP-8146N|ensemblfungi:YIL120W(gene)|ensemblfungi:YIL120W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:craih0RZ0BVRFEToT3Tqtn177a8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4B82C618CAEF1EB2|rigid:MsPaQDvlylHgc7UnGiOMJ8Hl8oY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36029 uniprotkb:P02829 intact:EBI-26939|uniprotkb:D6VX26|ensemblfungi:YKL174C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tpo5_yeast(display_long)|uniprotkb:YKL639(orf name)|uniprotkb:YKL174C(locus name)|uniprotkb:TPO5(gene name)|psi-mi:TPO5(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864278 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012747.1|sgd:S000001657|dip:DIP-4038N|ensemblfungi:YKL174C(gene)|ensemblfungi:YKL174C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006865"(amino acid transport)|go:"GO:0015203"(polyamine transmembrane transporter activity)|go:"GO:0015846"(polyamine transport)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:D+zdKGk3VfQ8BuP8F7mlJSRLK6A559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:802BC378B5EEC77E|rigid:/PXCYDq4U4Hazsh6sPqG3PSJ/+U false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03795 uniprotkb:P02829 intact:EBI-27332|uniprotkb:D6VZX6|ensemblfungi:YMR155W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ym30_yeast(display_long)|uniprotkb:YM8520.04(orf name)|uniprotkb:YMR155W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864283 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013876.1|sgd:S000004764|dip:DIP-4428N|mint:Q03795|ensemblfungi:YMR155W(gene)|ensemblfungi:YMR155W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR010658(Nodulin-like)|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:63B74B8359920A6D crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:W8ylgrEjuOOT0JRnJRPi+lC9XcQ559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D7324F9259C93621|rigid:j1qncBc/bPCRN3kxBXFvnqV1NGY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08980 uniprotkb:P02829 intact:EBI-38819|uniprotkb:D6W3A6|ensemblfungi:YPL264C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp264_yeast(display_long)|uniprotkb:YPL264C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864288 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015059.1|sgd:S000006185|dip:DIP-8870N|ensemblfungi:YPL264C(gene)|ensemblfungi:YPL264C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000620(Protein of unknown function DUF6, transmembrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:cyiMzdZ93h1kFYCu+H74QXhbPKU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:54853E47C4169429|rigid:8SDtl/KOdCcV83FmLG7Cb8zip1I false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P53394 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-18543|uniprotkb:D6W414|ensemblfungi:YPR003C psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:sulx_yeast(display_long)|uniprotkb:LPZ3C(orf name)|uniprotkb:YP9723.03C(orf name)|uniprotkb:YPR003C(locus name) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864293 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N interpro:IPR036513|reactome:R-SCE-174362|reactome:R-SCE-427601|ensemblfungi:YPR003C(gene)|ensemblfungi:YPR003C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008271"(secondary active sulfate transmembrane transporter activity)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|interpro:IPR001902(Sulphate anion transporter)|interpro:IPR002645(Sulphate transporter/antisigma-factor antagonist STAS)|interpro:IPR011547(Sulphate transporter)|interpro:IPR018045|refseq:NP_015328.1|sgd:S000006207|dip:DIP-5055N|mint:P53394 - crc64:D7C35676D668FB63 crc64:4558DA8B79803E6E - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:pzhfeEpbJNfLLDjN/Zz2a8vaeeE559292 intact-crc:693319ACB1C67041|rigid:ynKKGGAjnLlC1wOA88cEKJEzbok false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25628 uniprotkb:P02829 intact:EBI-2801|uniprotkb:D6VR57|ensemblfungi:YCR048W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:are1_yeast(display_long)|uniprotkb:ARE1(gene name)|psi-mi:ARE1(display_short)|uniprotkb:SAT2(gene name synonym)|uniprotkb:YCR048W(locus name)|uniprotkb:YCR48W(orf name)|uniprotkb:Sterol-ester synthase 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864298 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009978.1|sgd:S000000644|dip:DIP-4998N|mint:P25628|ensemblfungi:YCR048W(gene)|ensemblfungi:YCR048W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008204"(ergosterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0034737"(ergosterol O-acyltransferase activity)|go:"GO:0034738"(lanosterol O-acyltransferase activity)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:FF72EFB9238B2205 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:tb8axrzq5QBkRqSVY2TLO+zDBR0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:617E7233A432829C|rigid:uPMnoD9QdeLGi3YTttHyFBDtnT8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53629 uniprotkb:P02829 intact:EBI-2808|uniprotkb:Q12673|uniprotkb:D6W1J4|ensemblfungi:YNR019W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:are2_yeast(display_long)|uniprotkb:ARE2(gene name)|psi-mi:ARE2(display_short)|uniprotkb:SAT1(gene name synonym)|uniprotkb:YNR019W(locus name)|uniprotkb:N3206(orf name)|uniprotkb:Sterol-ester synthase 2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864303 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014416.1|sgd:S000005302|dip:DIP-4050N|mint:P53629|ensemblfungi:YNR019W(gene)|ensemblfungi:YNR019W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008204"(ergosterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034737"(ergosterol O-acyltransferase activity)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:035FC4ED9C7CD830 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:19pHOCLa6/S7I+HrOY1OAtUJ3ww559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:27094ABD62F95696|rigid:ukhpCGAHVE+odGDoU5N9mTCi5E8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04076 uniprotkb:P02829 intact:EBI-2877|uniprotkb:D3DKW3|ensemblfungi:YHR018C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:arly_yeast(display_long)|uniprotkb:ARG4(gene name)|psi-mi:ARG4(display_short)|uniprotkb:Arginosuccinase(gene name synonym)|uniprotkb:YHR018C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864308 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011882.1|sgd:S000001060|reactome:R-SCE-70635|dip:DIP-4306N|ensemblfungi:YHR018C(gene)|ensemblfungi:YHR018C_mRNA(transcript)|go:"GO:0004056"(argininosuccinate lyase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|interpro:IPR000362(Fumarate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|interpro:IPR029419 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:2E5C01E53B3E163B crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:8eTYwblkPghdrHrdpWQUiR2X6fM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:3F716B5051835103|rigid:ujUT/YvRCITqEma+hdKHgMxQyaU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06598 uniprotkb:P02829 intact:EBI-2122|uniprotkb:D6W4J9|ensemblfungi:YPR201W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:arr3_yeast(display_long)|uniprotkb:ARR3(gene name)|psi-mi:ARR3(display_short)|uniprotkb:ACR3(gene name synonym)|uniprotkb:Arsenic compounds resistance protein 3(gene name synonym)|uniprotkb:"As(III)/H(+) and Sb(III)/H(+)antiporter"(gene name synonym)|uniprotkb:P9677.2(orf name)|uniprotkb:YPR201W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864313 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015527.1|sgd:S000006405|dip:DIP-3797N|ensemblfungi:YPR201W(gene)|ensemblfungi:YPR201W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015104"(antimonite transmembrane transporter activity)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015699"(antimonite transport)|go:"GO:0015700"(arsenite transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046685"(response to arsenic-containing substance)|interpro:IPR002657("Bile acid:sodium symporter")|interpro:IPR004706(Arsenical-resistance protein ACR3)|interpro:IPR038770 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:hD7p3e1xaKpnUcLGC+3GUx4abds559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:FECDAA5D651731FC|rigid:1sgeMG7BhDHeeocwGIuyvZWo/ds false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46993 uniprotkb:P02829 intact:EBI-26150|uniprotkb:D6VW18|ensemblfungi:YJL170C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:asg7_yeast(display_long)|uniprotkb:YJL170C(locus name)|uniprotkb:J0514(orf name)|uniprotkb:ASG7(gene name)|psi-mi:ASG7(display_short)|uniprotkb:A-specific gene 7 protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864318 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003706|refseq:NP_012365.2|dip:DIP-5416N|ensemblfungi:YJL170C(gene)|ensemblfungi:YJL170C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:6H8VY/a35Z1SmU1HdFNVxM7KhHM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9A6A86C744BCCEC0|rigid:2svaR01vRXNnzsm9n22ochSaMgA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38270 uniprotkb:P02829 intact:EBI-2699|uniprotkb:D6VQC5|ensemblfungi:YBR128C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:atg14_yeast(display_long)|uniprotkb:ATG14(gene name)|psi-mi:ATG14(display_short)|uniprotkb:APG14(gene name synonym)|uniprotkb:YBR128C(locus name)|uniprotkb:YBR1003(orf name)|uniprotkb:CVT12(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 12(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864323 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009686.1|sgd:S000000332|dip:DIP-2741N|mint:P38270|ensemblfungi:YBR128C(gene)|ensemblfungi:YBR128C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR018791|interpro:IPR023261 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:202039BC7EC8BB16 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:2EgOCBKZFO6Gvj0RB/MM8jV0k1s559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:272BB2693ECBB8DA|rigid:AeSnC58TUzDuFmUqlVr3lrERrdA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06604 uniprotkb:P02829 intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864328 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:0406389224194044|rigid:tNhLyFff+3n5BH/IsTDyOUZ/3fA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07991 uniprotkb:P02829 intact:EBI-12430|ensemblfungi:YLR438W|uniprotkb:D6VZ72 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:oat_yeast(display_long)|uniprotkb:CAR2(gene name)|psi-mi:CAR2(display_short)|uniprotkb:CARGB(gene name synonym)|uniprotkb:YLR438W(locus name)|uniprotkb:L9753.2(orf name)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864333 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR438W(gene)|ensemblfungi:YLR438W_mRNA(transcript)|go:"GO:0004587"(ornithine-oxo-acid transaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006591"(ornithine metabolic process)|go:"GO:0010121"(arginine catabolic process to proline via ornithine)|go:"GO:0019544"(arginine catabolic process to glutamate)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050155"("ornithine(lysine) transaminase activity")|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|refseq:NP_013542.1|sgd:S000004430|dip:DIP-1225N|reactome:R-SCE-8964539 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A0B6BE492FC5C1B8 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yDHpJ9F41bj9y7BFrkgMqSt+R08559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:503DF85C336C28D9|rigid:/l//d8KkSqD3uaQ/9bmAOLh3OEw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40558 uniprotkb:P02829 intact:EBI-24924|uniprotkb:D6VVS7|ensemblfungi:YIL003W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cfd1_yeast(display_long)|uniprotkb:Cytosolic Fe-S cluster-deficient protein 1(gene name synonym)|uniprotkb:Ribosomal export protein 19(gene name synonym)|uniprotkb:CFD1(gene name)|psi-mi:CFD1(display_short)|uniprotkb:DRE3(gene name synonym)|uniprotkb:RIX19(gene name synonym)|uniprotkb:YIA3W(orf name)|uniprotkb:YIL003W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864338 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033756|refseq:NP_012263.1|sgd:S000001265|interpro:IPR019591|interpro:IPR000808(Mrp, conserved site)|interpro:IPR027417|interpro:IPR028600|ensemblfungi:YIL003W(gene)|ensemblfungi:YIL003W_mRNA(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1904564"(Nbp35-Cfd1 ATPase complex) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:QJ1DmeXQVhP0c8AnkoIHHFducCg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:AD612BCC99350364|rigid:PFVPMCokhe4+cTi0GvT10I4ZYR4 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04802 uniprotkb:P02829 intact:EBI-18655|uniprotkb:D6VXY6|ensemblfungi:YLL018C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sydc_yeast(display_long)|uniprotkb:DPS1(gene name)|psi-mi:DPS1(display_short)|uniprotkb:APS(gene name synonym)|uniprotkb:APS1(gene name synonym)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:L1295(orf name)|uniprotkb:YLL018C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864343 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013083.1|sgd:S000003941|ensemblfungi:YLL018C(gene)|ensemblfungi:YLL018C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1ASY|rcsb pdb:1ASZ|rcsb pdb:1EOV|dip:DIP-4093N|mint:P04802 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6656279B3E9011A5 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Rr9kHQcG78vfO3DYbDL+FDBevUw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D63A1FB3F340433C|rigid:B975eKDlF7iIS9HrzDz91rFGASY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05871 uniprotkb:P02829 intact:EBI-36568|uniprotkb:D6VYS8|ensemblfungi:YLR284C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:eci1_yeast(display_long)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),Delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:ECI1(gene name)|psi-mi:ECI1(display_short)|uniprotkb:YLR284C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864348 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013386.1|sgd:S000004274|dip:DIP-1692N|ensemblfungi:YLR284C(gene)|ensemblfungi:YLR284C_mRNA(transcript)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR001753(Crotonase, core)|interpro:IPR029045|rcsb pdb:1HNO|rcsb pdb:1HNU|rcsb pdb:1K39|rcsb pdb:1PJH|rcsb pdb:4ZDB|rcsb pdb:4ZDC|rcsb pdb:4ZDD|rcsb pdb:4ZDE|rcsb pdb:4ZDF ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:BdCDQdLb5WRjWinQ5/db1LyHBes559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:8865A8723D100610|rigid:Vx1hnFRmXj+ro5bc28PE5V3wGeg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22140 uniprotkb:P02829 intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864353 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E653272DA0C58D54|rigid:KdRIFTt9W49HYwVAG3zxvzbMNns false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15625 uniprotkb:P02829 intact:EBI-18678|uniprotkb:D6VTK8|ensemblfungi:YFL022C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:syfa_yeast(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:YFL022C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864358 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116631.1|sgd:S000001872|ensemblfungi:YFL022C(gene)|ensemblfungi:YFL022C_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR040586|interpro:IPR040725|dip:DIP-5428N|mint:P15625 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:50B7EAC675AB559B crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:hOEtrjcfIHQLY9FwCDb3XI593A4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:DF02F60B0B92D035|rigid:jOd03fnLjXSFaP/YH2NFHL6tAis false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32621 uniprotkb:P02829 intact:EBI-7511|uniprotkb:D3DLK7|ensemblfungi:YEL042W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gda1_yeast(display_long)|uniprotkb:SYGP-ORF16(orf name)|uniprotkb:YEL042W(locus name)|uniprotkb:GDA1(gene name)|psi-mi:GDA1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864363 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010872.1|sgd:S000000768|reactome:R-SCE-8850843|dip:DIP-5284N|ensemblfungi:YEL042W(gene)|ensemblfungi:YEL042W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004382"(guanosine-diphosphatase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009134"(nucleoside diphosphate catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017110"(nucleoside-diphosphatase activity)|go:"GO:0045134"(uridine-diphosphatase activity)|interpro:IPR000407(Nucleoside phosphatase GDA1/CD39) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:9A61182D5ED22ADF crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:6w7QyW9KRQQqmWA1119SDTWdUcE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E13F41EBAEF81D2D|rigid:9VN4In4fMM9ocUh79bQ9nqh42u8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38720 uniprotkb:P02829 intact:EBI-1965|uniprotkb:D3DLD1|ensemblfungi:YHR183W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:6pgd1_yeast(display_long)|uniprotkb:GND1(gene name)|psi-mi:GND1(display_short)|uniprotkb:YHR183W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864368 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001226|refseq:NP_012053.3|dip:DIP-6604N|mint:P38720|ensemblfungi:YHR183W(gene)|ensemblfungi:YHR183W_mRNA(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR036291|rcsb pdb:2P4Q|reactome:R-SCE-71336 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:55CAE5DACDC6A00B crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:8nBsN83LnQMIoQOqo1H+uOiTFsU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:ED424E70C71231E3|rigid:Yh5H8ee3qehtrs+48udk+ouMbcA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02784 uniprotkb:P02829 intact:EBI-29427|uniprotkb:D6W3V5|ensemblfungi:YPL059W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:glrx5_yeast(display_long)|uniprotkb:LPE13W(orf name)|uniprotkb:YPL059W(locus name)|uniprotkb:GRX5(gene name)|psi-mi:GRX5(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864373 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015266.1|sgd:S000005980|dip:DIP-1352N|mint:Q02784|ensemblfungi:YPL059W(gene)|ensemblfungi:YPL059W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:3GX8|reactome:R-SCE-1362409 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:BewcU5fU1vugLOIRw1Jj00uk6sA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BA09D0A022F0E7BC|rigid:1wMTCddEmakGl+meeSkQ6DWf5Jc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47119 uniprotkb:P02829 intact:EBI-8147|ensemblfungi:YJR069C|uniprotkb:D6VWP0 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:itpa_yeast(display_long)|uniprotkb:HAM1(gene name)|psi-mi:HAM1(display_short)|uniprotkb:YJR069C(locus name)|uniprotkb:J1811(orf name)|uniprotkb:Hydroxylaminopurine sensitivity protein 1(gene name synonym)|uniprotkb:Non-canonical purine NTP pyrophosphatase(gene name synonym)|uniprotkb:Non-standard purine NTP pyrophosphatase(gene name synonym)|uniprotkb:Nucleoside-triphosphate diphosphatase(gene name synonym)|uniprotkb:Nucleoside-triphosphate pyrophosphatase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864378 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJR069C(gene)|ensemblfungi:YJR069C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|refseq:NP_012603.1|sgd:S000003830|mint:P47119|dip:DIP-5491N|go:"GO:0005737"(cytoplasm)|go:"GO:0008828"(dATP pyrophosphohydrolase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009213"(pyrimidine deoxyribonucleoside triphosphate catabolic process)|go:"GO:0009217"(purine deoxyribonucleoside triphosphate catabolic process)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0035870"(dITP diphosphatase activity)|go:"GO:0036217"(dGTP diphosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0036219"(GTP diphosphatase activity)|go:"GO:0036220"(ITP diphosphatase activity)|go:"GO:0036221"(UTP diphosphatase activity)|go:"GO:0036222"(XTP diphosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR002637(Ham1-like protein)|interpro:IPR027502|interpro:IPR029001|reactome:R-SCE-74259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:nHNWwDLycZ4ObTbIAOyE1AZeTJs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2E64510D7E398B56|rigid:Y6jEeEEmvsOCHjbv+WGvxrOhg6w false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02293 uniprotkb:P02829 intact:EBI-8088|uniprotkb:D6VSK6|ensemblfungi:YDR224C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:h2b1_yeast(display_long)|uniprotkb:HTB1(gene name)|psi-mi:HTB1(display_short)|uniprotkb:H2B1(gene name synonym)|uniprotkb:SPT12(gene name synonym)|uniprotkb:YDR224C(locus name)|uniprotkb:YD9934.09C(orf name)|uniprotkb:Suppressor of Ty protein 12(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864383 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002632|refseq:NP_010510.3|dip:DIP-416N|mint:P02293|ensemblfungi:YDR224C(gene)|ensemblfungi:YDR224C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006301"(postreplication repair)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:2JSS|rcsb pdb:4KUD|rcsb pdb:4M6B|rcsb pdb:4WNN|rcsb pdb:5BT1|rcsb pdb:6AE8|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214847|reactome:R-SCE-5689880|reactome:R-SCE-9018519 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:9F5E9CFB341DB399 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:ttEQevZ02vH0sVOHaYh+GB35tXs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:DCA2004BDBB739A3|rigid:d8jCZPATpEr+XVtU0nwlb9nPboQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04344 uniprotkb:P02829 intact:EBI-8416|uniprotkb:D6VRM5|ensemblfungi:YDL125C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hnt1_yeast(display_long)|uniprotkb:HNT1(gene name)|psi-mi:HNT1(display_short)|uniprotkb:HIT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein HNT1(gene name synonym)|uniprotkb:Hit family protein 1(gene name synonym)|uniprotkb:YDL125C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864388 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010158.1|sgd:S000002283|dip:DIP-2760N|mint:Q04344|ensemblfungi:YDL125C(gene)|ensemblfungi:YDL125C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039384 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:93se/ObwboPzYXLyIpTm7RrKhl0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:89CEF3CE78071620|rigid:jaQKUuQfuKHDnosGtdmAZww5yLM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07263 uniprotkb:P02829 intact:EBI-18711|uniprotkb:Q12095|uniprotkb:D6W443|ensemblfungi:YPR033C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:syh_yeast(display_long)|uniprotkb:HTS1(gene name)|psi-mi:HTS1(display_short)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:YP9367.13C(orf name)|uniprotkb:YPR033C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864393 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015358.1|sgd:S000006237|ensemblfungi:YPR033C(gene)|ensemblfungi:YPR033C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004812"(aminoacyl-tRNA ligase activity)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|dip:DIP-3909N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:8BDCCEAB4DD73973 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:S0bdXIh5cesydGumiinoiiwohuM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7F89773DB6B8097B|rigid:Q8HBzbQVeaU8PWJboZlKrM01uKk false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08227 uniprotkb:P02829 intact:EBI-38678|uniprotkb:D6W202|ensemblfungi:YOL065C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:inp54_yeast(display_long)|uniprotkb:INP54(gene name)|psi-mi:INP54(display_short)|uniprotkb:YOL065C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864398 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014576.1|sgd:S000005426|mint:Q08227|dip:DIP-2768N|ensemblfungi:YOL065C(gene)|ensemblfungi:YOL065C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Cb8KRlagjk9+BBSYstO77BPYua8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:837F78DF984B8C14|rigid:kVMx652CqWTbCV4yEin2V5JdNcA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99393 uniprotkb:P02829 intact:EBI-32475|uniprotkb:Q6B2Z2|uniprotkb:D6W1W7|ensemblfungi:YOL101C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:izh4_yeast(display_long)|uniprotkb:Implicated in zinc homeostasis protein 4(gene name synonym)|uniprotkb:IZH4(gene name)|psi-mi:IZH4(display_short)|uniprotkb:YOL101C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864403 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014540.1|sgd:S000005461|dip:DIP-5059N|ensemblfungi:YOL101C(gene)|ensemblfungi:YOL101C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR004254(Hly-III related) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:XjOcXEPH6g8vq/BJHfV1gDdY6to559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:EAC7F9F7234C1E55|rigid:c6vx8JDHJW9VgJ2OKLtmSpydzIQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12122 uniprotkb:P02829 intact:EBI-8508|uniprotkb:E9P8Z7|uniprotkb:D6VRL8|ensemblfungi:YDL131W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hosm_yeast(display_long)|uniprotkb:D2195(orf name)|uniprotkb:YDL131W(locus name)|uniprotkb:LYS21(gene name)|psi-mi:LYS21(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864408 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010151.1|sgd:S000002289|dip:DIP-4634N|mint:Q12122|ensemblfungi:YDL131W(gene)|ensemblfungi:YDL131W_mRNA(transcript)|go:"GO:0004410"(homocitrate synthase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0046872"(metal ion binding)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR011872(Homocitrate synthase, fungi and archaea)|interpro:IPR013785(Aldolase-type TIM barrel) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:XA2Z9ramCU3LX1hQw31rwIRjlk8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E9B78007EB962B7F|rigid:FZGdcUVx70C3rGkDEM3xSCzQLLg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32419 uniprotkb:P02829 intact:EBI-10598|uniprotkb:Q12689|ensemblfungi:YDL078C|uniprotkb:D6VRS1 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mdhp_yeast(display_long)|uniprotkb:D2468(orf name)|uniprotkb:YDL078C(locus name)|uniprotkb:MDH3(gene name)|psi-mi:MDH3(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864413 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL078C(gene)|ensemblfungi:YDL078C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006735"(NADH regeneration)|go:"GO:0030060"(L-malate dehydrogenase activity)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|rcsb pdb:5ZI2|rcsb pdb:5ZI3|rcsb pdb:5ZI4|go:"GO:0005777"(peroxisome)|refseq:NP_010205.1|sgd:S000002236|mint:P32419|dip:DIP-6473N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:54725114B2CAD6A5 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:AWzfeNhQ7XQP9rOGRRZ7t/XLy/M559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:F2E0A3BA31A22662|rigid:Pj1FpO1AtL5KeOrF20BQkF698JY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02196 uniprotkb:P02829 intact:EBI-9485|ensemblfungi:YKL001C|uniprotkb:D6VXT6 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:kaps_yeast(display_long)|uniprotkb:ATP adenosine-5'-phosphosulfate 3'-phosphotransferase(gene name synonym)|uniprotkb:YKL001C(locus name)|uniprotkb:MET14(gene name)|psi-mi:MET14(display_short)|uniprotkb:Adenosine-5'-phosphosulfate kinase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864418 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL001C(gene)|ensemblfungi:YKL001C_mRNA(transcript)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004020"(adenylylsulfate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019379"("sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)")|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|interpro:IPR002891(Adenylylsulphate kinase, C-terminal)|interpro:IPR027417|sgd:S000001484|reactome:R-SCE-174362|refseq:NP_012925.3|dip:DIP-1972N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:qsibLsUWllCFge4Xz/VTNeALTgc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:C93EC9D607B95859|rigid:BKQerSo2N3r3km5++zUAQMyr4AM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40549 uniprotkb:P02829 intact:EBI-11107|ensemblfungi:YIL014W|uniprotkb:D6VVR6 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mnt3_yeast(display_long)|uniprotkb:MNT3(gene name)|psi-mi:MNT3(display_short)|uniprotkb:YIL014W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864423 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL014W_mRNA(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022751|interpro:IPR029044|ensemblfungi:YIL014W(gene)|refseq:NP_012251.3|sgd:S000001276|dip:DIP-4122N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:xQN9nCWjF6bPOdZPtL8Ajt6PYTc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7FDC9C54F41D5B1D|rigid:5vvkZ+STyeQpBaLWcLxqmAgTApI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53927 uniprotkb:P02829 intact:EBI-28853|uniprotkb:D6W171|ensemblfungi:YNL110C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:nop15_yeast(display_long)|uniprotkb:YNL110C(locus name)|uniprotkb:N1954(orf name)|uniprotkb:Nucleolar protein 15(gene name synonym)|uniprotkb:NOP15(gene name)|psi-mi:NOP15(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864428 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014289.1|sgd:S000005054|dip:DIP-4741N|mint:P53927|ensemblfungi:YNL110C(gene)|ensemblfungi:YNL110C_mRNA(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034469|interpro:IPR035979|rcsb pdb:3JCT|rcsb pdb:5T9P|rcsb pdb:5Z3G|rcsb pdb:6C0F|rcsb pdb:6CB1|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6EM3|rcsb pdb:6EM4|rcsb pdb:6EM5|rcsb pdb:6M62|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BTB ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:EC86E3C77C863292 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:WHuY5zx7DUsm1G+00Bc6wM8JAJc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2B73A514E6C41391|rigid:EDbxxwcW4FDQra/484ta3lrhvTA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21147 uniprotkb:P02829 intact:EBI-2098|ensemblfungi:YGL055W|uniprotkb:D6VU86|uniprotkb:E9P911 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:aco1_yeast(display_long)|uniprotkb:OLE1(gene name)|psi-mi:OLE1(display_short)|uniprotkb:Stearoyl-CoA desaturase 1(gene name synonym)|uniprotkb:Fatty acid desaturase 1(gene name synonym)|uniprotkb:YGL055W(locus name)|uniprotkb:Delta 9 fatty acid desaturase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864433 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL055W(gene)|ensemblfungi:YGL055W_mRNA(transcript)|go:"GO:0000001"(mitochondrion inheritance)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|sgd:S000003023|refseq:NP_011460.3|dip:DIP-5026N|mint:P21147|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001522(Fatty acid desaturase, type 1, C-terminal)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR009160(Delta-9 acyl-CoA desaturase with haem/steroid binding region)|interpro:IPR015876(Fatty acid desaturase, type 1, core)|interpro:IPR018506|interpro:IPR036400 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A6CC78DD4210ECCA crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Ibp4I76IX/sMf5kLO05pTBZ3TNE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A0BF3A6E2490F9FB|rigid:Kg3MIRyXxa2RTQkGVNqFFBNYpqY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12462 uniprotkb:P02829 intact:EBI-13198|uniprotkb:D6W1S2|ensemblfungi:YOL147C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pex11_yeast(display_long)|uniprotkb:PEX11(gene name)|psi-mi:PEX11(display_short)|uniprotkb:PMP24(gene name synonym)|uniprotkb:PMP27(gene name synonym)|uniprotkb:O0454(orf name)|uniprotkb:YOL147C(locus name)|uniprotkb:Peroxin-11(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864438 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014494.1|sgd:S000005507|mint:Q12462|dip:DIP-3839N|ensemblfungi:YOL147C(gene)|ensemblfungi:YOL147C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0044375"(regulation of peroxisome size)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-SCE-9603798|go:"GO:0005783"(endoplasmic reticulum) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Wgd0xHDx1jc9msL55PpTWFNL7cA559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:AB75DA0F9BAB6ED2|rigid:N4V3S86tKReI8huwKo3xJQxfGK8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38075 uniprotkb:P02829 intact:EBI-13086|uniprotkb:D6VQ35|ensemblfungi:YBR035C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pdx3_yeast(display_long)|uniprotkb:PDX3(gene name)|psi-mi:PDX3(display_short)|uniprotkb:YBR035C(locus name)|uniprotkb:YBR0321(orf name)|uniprotkb:PNP/PMP oxidase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864443 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009591.1|sgd:S000000239|reactome:R-SCE-964975|dip:DIP-4324N|ensemblfungi:YBR035C(gene)|ensemblfungi:YBR035C_mRNA(transcript)|go:"GO:0004733"(pyridoxamine-phosphate oxidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0008615"(pyridoxine biosynthetic process)|go:"GO:0009443"(pyridoxal 5'-phosphate salvage)|go:"GO:0010181"(FMN binding)|interpro:IPR000659(Pyridoxamine 5'-phosphate oxidase)|interpro:IPR011576(Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core)|interpro:IPR012349(FMN-binding split barrel)|interpro:IPR019576|interpro:IPR019740|rcsb pdb:1CI0 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:8B648A219763160E crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:XLDqaEJ2MiTvLskEdvdtHIHu1X8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9FF4B1EB6A26B61B|rigid:N3OL0pFrO0KPp1pEPPd8WH3Z+mg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07275 uniprotkb:P02829 intact:EBI-14303|uniprotkb:D3DKY4|ensemblfungi:YHR037W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:put2_yeast(display_long)|uniprotkb:PUT2(gene name)|psi-mi:PUT2(display_short)|uniprotkb:L-glutamate gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:YHR037W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864448 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR037W(gene)|ensemblfungi:YHR037W_mRNA(transcript)|go:"GO:0003842"(1-pyrroline-5-carboxylate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0010133"(proline catabolic process to glutamate)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|refseq:NP_011902.1|sgd:S000001079|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR005931(Delta-1-pyrroline-5-carboxylate dehydrogenase 1)|rcsb pdb:4OE4|rcsb pdb:4OE6|interpro:IPR029510|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:qfhIAlssFv5Dhy5ckgVhCzum5Yg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9B57041865F7BF80|rigid:I7DKyAgRtLdsqXcy7JxZmdy3l80 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P52489 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-9895|uniprotkb:D6W342|ensemblfungi:YOR347C psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:kpyk2_yeast(display_long)|uniprotkb:O6342(orf name)|uniprotkb:PYK2(gene name)|psi-mi:PYK2(display_short)|uniprotkb:YOR347C(locus name) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864453 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N sgd:S000005874|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:1904408"(melatonin binding)|reactome:R-SCE-6798695|reactome:R-SCE-70171|ensemblfungi:YOR347C(gene)|ensemblfungi:YOR347C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|refseq:NP_014992.3|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|mint:P52489|interpro:IPR036918 - crc64:D7C35676D668FB63 - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:IHNK0cdSLgrkeEJF4sRuDovzHGk559292 intact-crc:561B1A940B14EB65|rigid:IImeilCM7DCZB2BIqykZ3taXLVU false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25611 uniprotkb:P02829 intact:EBI-22052|uniprotkb:D6VRA6|ensemblfungi:YCR106W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:rds1_yeast(display_long)|uniprotkb:YCR106W(locus name)|uniprotkb:RDS1(gene name)|psi-mi:RDS1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864458 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010031.1|sgd:S000000703|dip:DIP-2014N|ensemblfungi:YCR106W(gene)|ensemblfungi:YCR106W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|mint:P25611 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:7DF91D86AF08E4E3 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:1um+FEn46D2/f4P58Zo/rIQSEZU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:1226D5C7FCB7E4A7|rigid:oi2VnzT/9AwMjtNpW/Cv972l+dE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P07279 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-15288|uniprotkb:D6W0P3 psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:rl18_yeast(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:RP28A(gene name synonym)|uniprotkb:YOL120C(locus name)|uniprotkb:RPL18B(gene name)|psi-mi:RPL18B(display_short)|uniprotkb:RP28B(gene name synonym)|uniprotkb:YNL301C(locus name)|uniprotkb:N0425(orf name)|uniprotkb:RP28(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864466 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N go:"GO:0022625"(cytosolic large ribosomal subunit)|sgd:S000005480(RPL18A)|sgd:S000005245(RPL18B)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|interpro:IPR000039(Ribosomal protein L18e)|cygd:YNL301c|cygd:YOL120c|rcsb pdb:1K5Y|rcsb pdb:1S1I|rcsb pdb:3IZS|rcsb pdb:3O58|rcsb pdb:3O5H|interpro:IPR021131|interpro:IPR021132|refseq:NP_014098.1|refseq:NP_014521.1 - crc64:D7C35676D668FB63 - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:86FYqzXCj53J/AFzhS7OtvmGwWs559292 intact-crc:43BD1E70D0A14B5E|rigid:eulS0X0hptzSgogbbsGQ/QANTVs false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:Q12461 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-32784|uniprotkb:D6W3L7|ensemblfungi:YPL152W psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:ptpa2_yeast(display_long)|uniprotkb:RRD2(gene name)|psi-mi:RRD2(display_short)|uniprotkb:Peptidyl-prolyl cis-trans isomerase PTPA-2(gene name synonym)|uniprotkb:Phosphotyrosyl phosphatase activator 2(gene name synonym)|uniprotkb:YPL152W(locus name)|uniprotkb:NOH1(gene name synonym)|uniprotkb:YPA2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864471 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N refseq:NP_015173.1|sgd:S000006073|dip:DIP-2558N|mint:Q12461|ensemblfungi:YPL152W(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008160"(protein tyrosine phosphatase activator activity)|go:"GO:0019888"(protein phosphatase regulator activity)|interpro:IPR004327(Phosphotyrosyl phosphatase activator, PTPA)|interpro:IPR037218|interpro:IPR043170|rcsb pdb:2IXN|ensemblfungi:YPL152W_mRNA(transcript) - crc64:D7C35676D668FB63 crc64:E0BE8A7EDD54E306 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:M4Z3IPFQcLYbvf9hHJ5zz0S27oE559292 intact-crc:454D3895B6FED3E5|rigid:lJoCCvn3/r/RonyVYHKJmVCP6/s false mutation increasing interaction:33-33 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07748 uniprotkb:P02829 intact:EBI-36080|uniprotkb:D6VRB3|ensemblfungi:YDL244W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:thi13_yeast(display_long)|uniprotkb:THI13(gene name)|psi-mi:THI13(display_short)|uniprotkb:Thiamine biosynthesis protein 13(gene name synonym)|uniprotkb:Thiamine pyrimidine synthase(gene name synonym)|uniprotkb:YDL244W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864476 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027939|sgd:S000002403|interpro:IPR015168(NMT1/THI5 like)|refseq:NP_010037.1|ensemblfungi:YDL244W(gene)|ensemblfungi:YDL244W_mRNA(transcript)|go:"GO:0009228"(thiamine biosynthetic process)|go:"GO:0009229"(thiamine diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106344"(4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:0hWCMqe/C0jO+5pl3vrkVgdFTBM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:54899800B144EBE1|rigid:bl+Xt7LARlgQUG3NM1yGTTw97zE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33296 uniprotkb:P02829 intact:EBI-19745|uniprotkb:D3DM07|ensemblfungi:YER100W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ubc6_yeast(display_long)|uniprotkb:UBC6(gene name)|psi-mi:UBC6(display_short)|uniprotkb:DOA2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase UBC6(gene name synonym)|uniprotkb:Ubiquitin carrier protein UBC6(gene name synonym)|uniprotkb:YER100W(locus name)|uniprotkb:E2 ubiquitin-conjugating enzyme 6(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864481 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000902|ensemblfungi:YER100W(gene)|ensemblfungi:YER100W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-SCE-9609523|refseq:NP_011026.3|dip:DIP-1713N|reactome:R-SCE-983168 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6D80C35ECC9CF5AD crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:oMsiJUWZq79Xez9RqWpgFGqWd9A559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:61568F1A95A2D863|rigid:/AoIa/D4AJKrx8exF2d6r3YGHzI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38349 uniprotkb:P02829 intact:EBI-21157|uniprotkb:D6VQR9|ensemblfungi:YBR273C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ubx7_yeast(display_long)|uniprotkb:YBR1741(orf name)|uniprotkb:YBR273C(locus name)|uniprotkb:UBX7(gene name)|psi-mi:UBX7(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864486 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009832.1|sgd:S000000477|mint:P38349|dip:DIP-4498N|ensemblfungi:YBR273C(gene)|ensemblfungi:YBR273C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|interpro:IPR001012(UBX)|interpro:IPR029071 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:5qnD0uPooYQPRZby9+kcjyXDb8Y559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:913BBF8B77C73A2D|rigid:fREIWT+xos3K3WqWaqQ1zuwkCmo false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32861 uniprotkb:P02829 intact:EBI-19987|uniprotkb:D6VXQ0|ensemblfungi:YKL035W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ugpa1_yeast(display_long)|uniprotkb:UGP1(gene name)|psi-mi:UGP1(display_short)|uniprotkb:YKL035W(locus name)|uniprotkb:YKL248(orf name)|uniprotkb:UDP-glucose pyrophosphorylase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864491 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001518|refseq:NP_012889.3|go:"GO:0070569"(uridylyltransferase activity)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|rcsb pdb:2I5K|reactome:R-SCE-173599|reactome:R-SCE-3322077|ensemblfungi:YKL035W(gene)|ensemblfungi:YKL035W_mRNA(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0006078"("(1->6)-beta-D-glucan biosynthetic process")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|dip:DIP-4534N|mint:P32861 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:9B9F4BED885E004D crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:5M60fHOmec4jPgidiOgmZxhfGzg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B6636569601053B1|rigid:WocXsR+H3/3BZh7FwiI99XrVILA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38272 uniprotkb:P02829 intact:EBI-21600|uniprotkb:D6VQC7|ensemblfungi:YBR130C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:she3_yeast(display_long)|uniprotkb:YBR1005(orf name)|uniprotkb:YBR130C(locus name)|uniprotkb:SHE3(gene name)|psi-mi:SHE3(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864496 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000334|refseq:NP_009688.3|mint:P38272|dip:DIP-2037N|ensemblfungi:YBR130C(gene)|ensemblfungi:YBR130C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0007533"(mating type switching)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051028"(mRNA transport)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR031398|rcsb pdb:4LL7|rcsb pdb:4LL8|rcsb pdb:4WNL|rcsb pdb:5M0I|rcsb pdb:5M0J ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:590404D2E140BB7A crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:HmP1/ozLaDCRVBA9eJ10x7CYNjI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9307917AF7529100|rigid:v2W3rpiHMOZJfRbO3kzjPeb6vio false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40073 uniprotkb:P02829 intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864501 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:E467A4D50AA3EDB6 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:DPpJB36kZxbFXugXajgs899epuY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:52D5BB74D663F7EF|rigid:F/qp9Tqr1sCjqhqvrrYVsv7V/EM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04658 uniprotkb:P02829 intact:EBI-27845|uniprotkb:D6VZA7|ensemblfungi:YML066C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sma2_yeast(display_long)|uniprotkb:YML066C(locus name)|uniprotkb:SMA2(gene name)|psi-mi:SMA2(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864506 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004531|refseq:NP_013645.1|mint:Q04658|ensemblfungi:YML066C(gene)|ensemblfungi:YML066C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032120"(ascospore-type prospore membrane formation)|go:"GO:0070583"(spore membrane bending pathway) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:9qhc9L3EkefzLBZ/CYVBgpVoYxU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:69E4FDF9131B5994|rigid:4MVtZG+cqpQwOuaZ3+aD/S2Pukw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35497 uniprotkb:P02829 intact:EBI-5861|uniprotkb:D6VWX7|ensemblfungi:YJR159W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:dhso1_yeast(display_long)|uniprotkb:SOR1(gene name)|psi-mi:SOR1(display_short)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)|uniprotkb:J2395(orf name)|uniprotkb:YJR159W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864511 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012693.1|sgd:S000003920|reactome:R-SCE-5652227|reactome:R-SCE-5661270|dip:DIP-1511N|ensemblfungi:YJR159W(gene)|ensemblfungi:YJR159W_mRNA(transcript)|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019318"(hexose metabolic process)|go:"GO:0046526"(D-xylulose reductase activity)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:I+fV5um18G8VVslApt0qf2fj4h4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:95EE011B603F227F|rigid:VtN/Z+tYHR5zw766kvdAudNojLU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03175 uniprotkb:P02829 intact:EBI-18117|uniprotkb:D6VZS4|ensemblfungi:YMR101C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:srt1_yeast(display_long)|uniprotkb:SRT1(gene name)|psi-mi:SRT1(display_short)|uniprotkb:"Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)"(gene name synonym)|uniprotkb:YM6543.08C(orf name)|uniprotkb:YMR101C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864516 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013819.1|sgd:S000004707|go:"GO:0019408"(dolichol biosynthetic process)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR018520|interpro:IPR036424|ensemblfungi:YMR101C(gene)|ensemblfungi:YMR101C_mRNA(transcript)|go:"GO:0002094"(polyprenyltransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016094"(polyprenol biosynthetic process)|dip:DIP-4439N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:D9eiSz2756s3jVcBRtOYWTrv57A559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9E2FA70F4781A357|rigid:ILQcKc5YPyBc+75VzWDqWkVO+G4 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38637 uniprotkb:P02829 intact:EBI-5580|uniprotkb:P35188|uniprotkb:D6VVU1|ensemblfungi:YIR011C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sts1_yeast(display_long)|uniprotkb:STS1(gene name)|psi-mi:STS1(display_short)|uniprotkb:DBF8(gene name synonym)|uniprotkb:YIR011C(locus name)|uniprotkb:YIB11C(orf name)|uniprotkb:SSM5(gene name synonym)|uniprotkb:Dumbbell former protein 8(gene name synonym)|uniprotkb:SEC23 suppressor 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864521 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012276.1|sgd:S000001450|dip:DIP-7670N|ensemblfungi:YIR011C(gene)|ensemblfungi:YIR011C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031144"(proteasome localization)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|interpro:IPR013868(Nuclear envelope, Cut8)|interpro:IPR038422 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Xp3Ak+DIOeIrzw1PgkV1/MInPLY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:96C1E6CAE118F739|rigid:cPKdBpmkN0kGRIBcxh9vYep4oyU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29547 uniprotkb:P02829 intact:EBI-6323|uniprotkb:Q9URC6|uniprotkb:D6W3W6|ensemblfungi:YPL048W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ef1g1_yeast(display_long)|uniprotkb:CAM1(gene name)|psi-mi:CAM1(display_short)|uniprotkb:TEF3(gene name synonym)|uniprotkb:Translation elongation factor 1B gamma 1(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1Bgamma 1(gene name synonym)|uniprotkb:Calcium and membrane-binding protein 1(gene name synonym)|uniprotkb:Calcium phospholipid-binding protein(gene name synonym)|uniprotkb:YPL048W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864526 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015277.1|sgd:S000005969|dip:DIP-6813N|mint:P29547|ensemblfungi:YPL048W(gene)|ensemblfungi:YPL048W_mRNA(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006414"(translational elongation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|rcsb pdb:1NHY|reactome:R-SCE-156842 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:QUHv6bmmvxO3lIkfd24HoXbxOng559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:89B4B766D23B25EF|rigid:ZH7VO+L0qcNmVbSBTvFiPp9tux8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49334 uniprotkb:P02829 intact:EBI-12527|uniprotkb:Q36757|uniprotkb:D6W151|ensemblfungi:YNL131W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tom22_yeast(display_long)|uniprotkb:MOM22(gene name synonym)|uniprotkb:TOM22(gene name)|psi-mi:TOM22(display_short)|uniprotkb:MAS17(gene name synonym)|uniprotkb:MAS22(gene name synonym)|uniprotkb:YNL131W(locus name)|uniprotkb:N1217(orf name)|uniprotkb:N1862(orf name)|uniprotkb:Mitochondrial 22 kDa outer membrane protein(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit(gene name synonym)|uniprotkb:Protein MAS17(gene name synonym)|uniprotkb:Mitochondrial 17 kDa assembly protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864531 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL131W(gene)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0030150"(protein import into mitochondrial matrix)|ensemblfungi:YNL131W_mRNA(transcript)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|interpro:IPR020951|rcsb pdb:6JNF|rcsb pdb:6UCU|rcsb pdb:6UCV|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_014268.1|sgd:S000005075|dip:DIP-2302N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6ACEC5D37D143CD3 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:XKrZuk3TqgMb6+ZV6pcTdZgdltM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:8A68D44FDB90C0A9|rigid:PHZ1O1vLqokhVuLsilKsGAVhMhE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22203 uniprotkb:P02829 intact:EBI-20268|uniprotkb:D6W328|ensemblfungi:YOR332W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:vate_yeast(display_long)|uniprotkb:VMA4(gene name)|psi-mi:VMA4(display_short)|uniprotkb:VAT5(gene name synonym)|uniprotkb:O6241(orf name)|uniprotkb:YOR332W(locus name)|uniprotkb:Vacuolar proton pump subunit E(gene name synonym)|uniprotkb:V-ATPase 27 kDa subunit(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864536 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-77387|sgd:S000005859|reactome:R-SCE-1222556|refseq:NP_014977.3|ensemblfungi:YOR332W(gene)|ensemblfungi:YOR332W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|rcsb pdb:2KZ9|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|dip:DIP-4595N|reactome:R-SCE-917977|reactome:R-SCE-9639288 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:7AC5169FF7E5A39C crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:g5fE3fwOSqcB4fXde9P8p6BD4T8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:0518B3CB98992F65|rigid:SY0W+Jpp0jUzq/2PLCPIWFm5d7k false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12416 uniprotkb:P02829 intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864541 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:013A41AC5DC1975F crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A87BFE5CB5275A89|rigid:BbDuKask99taoLbfW24WK9iun08 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07993 uniprotkb:P02829 intact:EBI-34737|uniprotkb:D6VY71|ensemblfungi:YLR070C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:xyl2_yeast(display_long)|uniprotkb:XYL2(gene name)|psi-mi:XYL2(display_short)|uniprotkb:Xylitol dehydrogenase(gene name synonym)|uniprotkb:YLR070C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864546 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013171.1|sgd:S000004060|dip:DIP-4533N|ensemblfungi:YLR070C(gene)|ensemblfungi:YLR070C_mRNA(transcript)|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0005999"(xylulose biosynthetic process)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019569"(L-arabinose catabolic process to xylulose 5-phosphate)|go:"GO:0042732"(D-xylose metabolic process)|go:"GO:0046526"(D-xylulose reductase activity)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|reactome:R-SCE-5652227|reactome:R-SCE-5661270 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:9UGBmZgwTrM8G5fRqD4x1WrUxfY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:30A5A4CAB25F1712|rigid:A0aMRzAKETImVZmrnRbjEg7qHKM false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47023 uniprotkb:P02829 intact:EBI-26045|uniprotkb:D6VW71 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yj41a_yeast(display_long)|uniprotkb:TY4A-J(gene name)|psi-mi:TY4A-J(display_short)|uniprotkb:YJL114W(locus name)|uniprotkb:J0775(orf name)|uniprotkb:YJLWTy4-1 GAG(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864551 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003650|refseq:NP_012422.2|dip:DIP-7219N|go:"GO:0000943"(retrotransposon nucleocapsid)|go:"GO:0003723"(RNA binding)|go:"GO:0032197"(transposition, RNA-mediated) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:/ph/KFDVicoMYXIKKyAmKpN+aFc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:764E6E751A60B496|rigid:HqmaQigs6KK6yYEPKxpP8oylAao false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43682 uniprotkb:P02829 intact:EBI-17040|uniprotkb:D6VXT0|ensemblfungi:YKL006C-A intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sft1_yeast(display_long)|uniprotkb:SFT1(gene name)|psi-mi:SFT1(display_short)|uniprotkb:YKL006C-A(locus name)|uniprotkb:YKL006BC(orf name)|uniprotkb:P14(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864556 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012919.3|ensemblfungi:YKL006C-A(gene)|ensemblfungi:YKL006C-A_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|sgd:S000002101|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-204005|dip:DIP-4355N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:69BC0B64E9A77C07 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:xpUUp4qzrBFyWwzRLIZ4gG5xaaM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B9F8ED8F9F31A0CD|rigid:a9N2B4jKkjv7NrKiRHOyWKceH0o false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P89113 uniprotkb:P02829 intact:EBI-5731|uniprotkb:D6W215|ensemblfungi:YOL052C-A intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ddr2_yeast(display_long)|uniprotkb:DDR2(gene name)|psi-mi:DDR2(display_short)|uniprotkb:YOL052BC(orf name)|uniprotkb:YOL053C-A(orf name)|uniprotkb:YOL052C-A(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864561 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005413|refseq:NP_014589.1|dip:DIP-7584N|ensemblfungi:YOL052C-A(gene)|ensemblfungi:YOL052C-A_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005737"(cytoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0070301"(cellular response to hydrogen peroxide) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Z/wXKbCKgy2WvokaFHNRzFgxaGY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D5CF379AADC5B4F3|rigid:xzTXgUzMYNPFTGAv1rnhZESZmr0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39721 uniprotkb:P02829 intact:EBI-20689|uniprotkb:D6VPG7|ensemblfungi:YAL049C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:aim2_yeast(display_long)|uniprotkb:YAL049C(locus name)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Altered inheritance rate of mitochondria protein 2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864566 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009350.1|sgd:S000000047|ensemblfungi:YAL049C(gene)|ensemblfungi:YAL049C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016787"(hydrolase activity)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|dip:DIP-2008N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:607298D79EECEF5B crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:X0+zB3NgVccCcMT9sBnkEiA4i5o559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:08D2775335CF2CEA|rigid:0Zo+JrnDFlQ3izw0I7hYfjoQzsQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38318 uniprotkb:P02829 intact:EBI-20993|uniprotkb:D6VQL6|ensemblfungi:YBR220C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yb70_yeast(display_long)|uniprotkb:YBR1510(orf name)|uniprotkb:YBR220C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864571 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009779.3|sgd:S000000424|reactome:R-SCE-425397|dip:DIP-5702N|ensemblfungi:YBR220C(gene)|ensemblfungi:YBR220C_mRNA(transcript)|go:"GO:0008521"(acetyl-CoA transmembrane transporter activity)|go:"GO:0015295"("solute:proton symporter activity")|go:"GO:0016021"(integral component of membrane)|interpro:IPR004752(AmpG-related permease)|interpro:IPR024371|interpro:IPR036259 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:PZY/5YNVBYhkTtwSPiSZ8A1GFns559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B12FE0553D7C5007|rigid:L0ETMm040y2Oxe2slBT1hWq+oh0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38323 uniprotkb:P02829 intact:EBI-10575|ensemblfungi:YBR227C|uniprotkb:D6VQM2 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:clpx_yeast(display_long)|uniprotkb:MCX1(gene name)|psi-mi:MCX1(display_short)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)|uniprotkb:YBR1524(orf name)|uniprotkb:YBR227C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864576 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR227C(gene)|ensemblfungi:YBR227C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042026"(protein refolding)|go:"GO:1904287"(positive regulation of protein-pyridoxal-5-phosphate linkage)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR027417|refseq:NP_009786.1|sgd:S000000431|mint:P38323|dip:DIP-6422N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A054D1618CD50A26 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:1gRZ7BHrcq+9pbjgJ6S+IxPD/kM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:7659B4B2AC601FE6|rigid:Xsslz71kLA0CclDyoQswzxSv4/g false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25584 uniprotkb:P02829 intact:EBI-21765|uniprotkb:D6VQW1|ensemblfungi:YCL056C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pex34_yeast(display_long)|uniprotkb:YCL056C(locus name)|uniprotkb:YCL56C(orf name)|uniprotkb:YCL433(orf name)|uniprotkb:PEX34(gene name)|psi-mi:PEX34(display_short)|uniprotkb:Peroxin-34(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864581 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000561|refseq:NP_009875.1|mint:P25584|dip:DIP-2040N|ensemblfungi:YCL056C(gene)|ensemblfungi:YCL056C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6035D449766516A6 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:IGoLOZeCbBNA4w+BG9mC/vxGfqs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B24BDACE7F11A699|rigid:JLRobLFAA0yZPvtr2qedCGX5MeA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25607 uniprotkb:P02829 intact:EBI-22033|uniprotkb:D6VRA2|ensemblfungi:YCR101C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ycz1_yeast(display_long)|uniprotkb:YCR101C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864586 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000698|refseq:NP_010025.1|dip:DIP-672N|ensemblfungi:YCR101C(gene)|ensemblfungi:YCR101C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016020"(membrane)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031778 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:HR35Vm47bWbcItnrF8ZqwWKj6AI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:F6F916E22FF8525C|rigid:bfL863yqT0RbH1mpTI4ZJd2Y9LY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12489 uniprotkb:P02829 intact:EBI-37592|uniprotkb:D6VRX7|ensemblfungi:YDL012C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yd012_yeast(display_long)|uniprotkb:D2880(orf name)|uniprotkb:YDL012C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864591 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002170|refseq:NP_010272.1|dip:DIP-1783N|ensemblfungi:YDL012C(gene)|ensemblfungi:YDL012C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:rMye29umlj+fGWWSGvix6a/eZls559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4353A033EBE6BB53|rigid:MP+lg30iTWzupwEeGEC6Pxz/urY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99190 uniprotkb:P02829 intact:EBI-31149|uniprotkb:D6VRX4|ensemblfungi:YDL015C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:tecr_yeast(display_long)|uniprotkb:TSC13(gene name)|psi-mi:TSC13(display_short)|uniprotkb:D2865(orf name)|uniprotkb:Trans-2-enoyl-CoA reductase(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 13(gene name synonym)|uniprotkb:YDL015C(locus name)|uniprotkb:Enoyl reductase TSC13(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864596 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010269.1|sgd:S000002173|dip:DIP-5599N|mint:Q99190|ensemblfungi:YDL015C(gene)|ensemblfungi:YDL015C_mRNA(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR039357|reactome:R-SCE-75876 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:rwzQIsU9w4fisk+hSklKSBFrjGo559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:3E6C9F412D0A6AFB|rigid:BJs1gIaKUvzWKk3qk7tVSEWxxpg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12516 uniprotkb:P02829 intact:EBI-38546|uniprotkb:P89897|uniprotkb:D6VRL6|uniprotkb:Q7LGS2|ensemblfungi:YDL133W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:srf1_yeast(display_long)|uniprotkb:SRF1(gene name)|psi-mi:SRF1(display_short)|uniprotkb:SPO14 regulatory factor 1(gene name synonym)|uniprotkb:D2185(orf name)|uniprotkb:YDL133W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864601 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010149.1|sgd:S000002291|dip:DIP-1802N|ensemblfungi:YDL133W(gene)|ensemblfungi:YDL133W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0071944"(cell periphery)|interpro:IPR037737 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:u5GEmykVXS+ZkFVarCEgs/63Lb0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6D31844AA4AEBE45|rigid:9K335Gj8e4kAObcjDEw+E6DiY1E false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12301 uniprotkb:P02829 intact:EBI-32458|uniprotkb:D6VRH2|ensemblfungi:YDL180W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yd180_yeast(display_long)|uniprotkb:YDL180W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864606 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002339|refseq:NP_010101.1|dip:DIP-8940N|ensemblfungi:YDL180W(gene)|ensemblfungi:YDL180W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:xyGhKNZgcxB18Gsc3DtC7qk7RGI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9C4A1A92F619C6F8|rigid:Oi4Bqcx/JRxuopxReb1CQoYnerU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07786 uniprotkb:P02829 intact:EBI-33572|uniprotkb:D6VRB1|ensemblfungi:YDL246C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:dhso2_yeast(display_long)|uniprotkb:SOR2(gene name)|psi-mi:SOR2(display_short)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym)|uniprotkb:YDL246C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864611 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010035.1|sgd:S000002405|mint:Q07786|dip:DIP-1512N|ensemblfungi:YDL246C(gene)|ensemblfungi:YDL246C_mRNA(transcript)|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019318"(hexose metabolic process)|go:"GO:0046526"(D-xylulose reductase activity)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|reactome:R-SCE-5652227|reactome:R-SCE-5661270 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:YDaTXvu5wxiE+qUFqnUyaiYH4S4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9FB599B1A53E6011|rigid:ZmknbN0ao/969cIUggquRL2YVDc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99288 uniprotkb:P02829 intact:EBI-30580|uniprotkb:Q05314|uniprotkb:P87337|uniprotkb:Q7LHX4|uniprotkb:D6VS38|ensemblfungi:YDR051C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:det1_yeast(display_long)|uniprotkb:DET1(gene name)|psi-mi:DET1(display_short)|uniprotkb:D4202(orf name)|uniprotkb:YDR051C(locus name)|uniprotkb:Decreased ergosterol transport protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864616 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002458|refseq:NP_010336.3|dip:DIP-1816N|mint:Q99288|ensemblfungi:YDR051C(gene)|ensemblfungi:YDR051C_mRNA(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032366"(intracellular sterol transport)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:vwXFLCqrDTeOaIJG7tr6C6a1cFs559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:49AD2B25B0102C51|rigid:qPmIKyGMfJPCy+L+jcxibhsA6DA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05637 uniprotkb:P02829 intact:EBI-37326|uniprotkb:D6VSR1|ensemblfungi:YDR281C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:phm6_yeast(display_long)|uniprotkb:PHM6(gene name)|psi-mi:PHM6(display_short)|uniprotkb:D9954.14(orf name)|uniprotkb:YDR281C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864621 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002689|refseq:NP_010567.1|dip:DIP-4775N|ensemblfungi:YDR281C(gene)|ensemblfungi:YDR281C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:4CXswPUeUtOazQ3jQAWOO1E96Lg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:B34DE9C4A95332E3|rigid:NsvvcAVGDLyqQmiwWgOzWsGS43U false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06676 uniprotkb:P02829 intact:EBI-30298|uniprotkb:D6VSV0|ensemblfungi:YDR319C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yft2_yeast(display_long)|uniprotkb:YFT2(gene name)|psi-mi:YFT2(display_short)|uniprotkb:FIT2A(gene name synonym)|uniprotkb:YDR319C(locus name)|uniprotkb:FIT family protein YFT2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864626 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010605.1|sgd:S000002727|dip:DIP-4731N|reactome:R-SCE-8964572|ensemblfungi:YDR319C(gene)|ensemblfungi:YDR319C_mRNA(transcript)|go:"GO:0005773"(vacuole)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0019915"(lipid storage)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1900480"(regulation of diacylglycerol biosynthetic process)|go:"GO:1900481"(negative regulation of diacylglycerol biosynthetic process)|interpro:IPR019388 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:gy1kXEPAQZisfcLxF3V95W1JR60559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6B7C79F5503E0E70|rigid:aOWGUjDU3KE2xCKNylYSEgt4LIA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04031 uniprotkb:P02829 intact:EBI-31091|uniprotkb:D6VT44|ensemblfungi:YDR412W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:rrp17_yeast(display_long)|uniprotkb:RRP17(gene name)|psi-mi:RRP17(display_short)|uniprotkb:YDR412W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864636 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010700.3|sgd:S000002820|dip:DIP-1264N|mint:Q04031|ensemblfungi:YDR412W(gene)|ensemblfungi:YDR412W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR019186 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:A61BB3AE3838CBAF crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:aC8bLzE4Tlvguem648OlXxm5iR0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2F0DE82E80DD9BC3|rigid:WYPizYYO7ZSS+ZpOTqD9m/g9NSw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40093 uniprotkb:P02829 intact:EBI-22730|uniprotkb:D3DM63|ensemblfungi:YER156C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yey6_yeast(display_long)|uniprotkb:YER156C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864641 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000958|refseq:NP_011083.3|dip:DIP-4187N|mint:P40093|ensemblfungi:YER156C(gene)|ensemblfungi:YER156C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR003226(Metal-dependent protein hydrolase) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Wyg4YOBCA+0S7KcknwRV9UglUq8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:5478CF9DAD1F3832|rigid:qj8dl6QV8927KCzUmCPCAal1jqQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38770 uniprotkb:P02829 intact:EBI-24507|uniprotkb:D3DKY3|ensemblfungi:YHR036W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:brl1_yeast(display_long)|uniprotkb:BRL1(gene name)|psi-mi:BRL1(display_short)|uniprotkb:BRR6-like protein 1(gene name synonym)|uniprotkb:YHR036W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864646 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011901.1|sgd:S000001078|dip:DIP-5580N|mint:P38770|ensemblfungi:YHR036W(gene)|ensemblfungi:YHR036W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR018767|interpro:IPR040202 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:gLJXF3VREvr8+oW8HZYTfHDho4A559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9741B0276965CF24|rigid:c++SrJHo5Kz+RwpeBK1tR6W2NBA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53344 uniprotkb:P02829 intact:EBI-4976|ensemblfungi:YGR295C|uniprotkb:D6VV69 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cos6_yeast(display_long)|uniprotkb:COS6(gene name)|psi-mi:COS6(display_short)|uniprotkb:YGR295C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864651 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001142(Yeast membrane protein DUP)|ensemblfungi:YGR295C(gene)|ensemblfungi:YGR295C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|refseq:NP_011811.1|sgd:S000003527|dip:DIP-5190N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:0D8FB6E350202ED2 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:kFcr7vcrJJo7rEM5xUY649KFgpw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4661E7775097EA21|rigid:eOLqf0o991I7M6GFfo4UFUY1gyw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40531 uniprotkb:P02829 intact:EBI-25006|uniprotkb:D6VVP1|ensemblfungi:YIL041W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gvp36_yeast(display_long)|uniprotkb:36 kDa Golgi vesicle protein(gene name synonym)|uniprotkb:GVP36(gene name)|psi-mi:GVP36(display_short)|uniprotkb:YIL041W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864656 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001303|refseq:NP_012223.3|mint:P40531|dip:DIP-7930N|ensemblfungi:YIL041W(gene)|ensemblfungi:YIL041W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|interpro:IPR018859|interpro:IPR027267 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:PKojvTfVp1QkcCntDVgxPVDO+g0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A43BC26F6FC79B98|rigid:Uku0wAwzxYi9GPvSTnB088bYvHU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40458 uniprotkb:P02829 intact:EBI-25256|uniprotkb:D6VVE1|ensemblfungi:YIL146C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:atg32_yeast(display_long)|uniprotkb:YIL146C(locus name)|uniprotkb:ATG32(gene name)|psi-mi:ATG32(display_short)|uniprotkb:Extracellular mutant protein 37(gene name synonym)|uniprotkb:ECM17(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864661 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001408|refseq:NP_012120.1|mint:P40458|ensemblfungi:YIL146C(gene)|ensemblfungi:YIL146C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0034045"(phagophore assembly site membrane)|rcsb pdb:3VXW|rcsb pdb:5WLP ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:G9JgaFYrrwsKy0QZ9O1/L2CHXH8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:682831DA88BCE7A8|rigid:B1HJh+npO70NpGRM4fVM57re5wA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32460 uniprotkb:P02829 intact:EBI-5676|uniprotkb:D6VVW1|ensemblfungi:YIR030C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:dcg1_yeast(display_long)|uniprotkb:YIR030C(locus name)|uniprotkb:DCG1(gene name)|psi-mi:DCG1(display_short) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864666 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012296.1|sgd:S000001469|mint:P32460|interpro:IPR015942(Asp/Glu/hydantoin racemase)|ensemblfungi:YIR030C(gene)|ensemblfungi:YIR030C_mRNA(transcript)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0036361"(racemase activity, acting on amino acids and derivatives) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:/Cn932MNF8cedbMZe3bv7xg2zUY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:73105C084EB4720A|rigid:QycZYpo95seySiCHgthrEdPEGOI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40586 uniprotkb:P02829 intact:EBI-25455|uniprotkb:D6VVX2|ensemblfungi:YIR042C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yiw2_yeast(display_long)|uniprotkb:YIR042C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864671 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012308.1|sgd:S000001481|dip:DIP-3962N|ensemblfungi:YIR042C(gene)|ensemblfungi:YIR042C_mRNA(transcript)|go:"GO:0008999"(ribosomal protein S5-alanine N-acetyltransferase activity)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:9BFa04d3iOPFxUgyUJPGfFe1Te8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:EEF68C6C04AB4400|rigid:V+dOYZFVdaECl2UaPWAooXgAl5Q false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47039 uniprotkb:P02829 intact:EBI-25893|uniprotkb:D6VWC2|ensemblfungi:YJL060W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:bna3_yeast(display_long)|uniprotkb:YJL060W(locus name)|uniprotkb:J1138(orf name)|uniprotkb:Biosynthesis of nicotinic acid protein 3(gene name synonym)|uniprotkb:BNA3(gene name)|psi-mi:BNA3(display_short)|uniprotkb:Kynurenine aminotransferase(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864676 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003596|refseq:NP_012475.3|mint:P47039|dip:DIP-6723N|ensemblfungi:YJL060W(gene)|ensemblfungi:YJL060W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0047536"(2-aminoadipate transaminase activity)|go:"GO:0097053"(L-kynurenine catabolic process)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:3B46|reactome:R-SCE-71240|reactome:R-SCE-8964208|reactome:R-SCE-8964539 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Fli6ip0tteNbMkQG9h7/IBow3ms559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4A7A07387C79F6B3|rigid:iZ2FDVkzGzg8RuEXf6q3/DVzCM4 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47129 uniprotkb:P02829 intact:EBI-25556|uniprotkb:D6VWQ2|ensemblfungi:YJR083C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:acf4_yeast(display_long)|uniprotkb:ACF4(gene name)|psi-mi:ACF4(display_short)|uniprotkb:J1857(orf name)|uniprotkb:YJR083C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864681 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003843|refseq:NP_012616.1|dip:DIP-2890N|ensemblfungi:YJR083C(gene)|ensemblfungi:YJR083C_mRNA(transcript) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:67kz2WXharaG1wxiEduByuaYYLU559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:07990B3FE414DEEB|rigid:W5QPzCB40AdwpwaZ62rm1dgfsPw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47166 uniprotkb:P02829 intact:EBI-25687|uniprotkb:D6VWV2|ensemblfungi:YJR134C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sgm1_yeast(display_long)|uniprotkb:YJR134C(locus name)|uniprotkb:J2120(orf name)|uniprotkb:SGM1(gene name)|psi-mi:SGM1(display_short)|uniprotkb:Slow growth on galactose and mannose protein 1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864686 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003895|refseq:NP_012668.3|dip:DIP-2973N|reactome:R-SCE-6811440|go:"GO:0005794"(Golgi apparatus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR022091|interpro:IPR022092|ensemblfungi:YJR134C(gene)|ensemblfungi:YJR134C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:BA47D1A7265BF3D9 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:LtrZowKRaTnjHGosS7XFOOE4sbE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:C3E21B8B5B84A551|rigid:8jtVN65EnVPJZB+/PuHVve/drrQ false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28496 uniprotkb:P02829 intact:EBI-26585|uniprotkb:D6VXS8|ensemblfungi:YKL008C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:lac1_yeast(display_long)|uniprotkb:LAC1(gene name)|psi-mi:LAC1(display_short)|uniprotkb:DGT1(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase LAC1(gene name synonym)|uniprotkb:YKL156(orf name)|uniprotkb:YKL008C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864691 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001491|refseq:NP_012917.3|mint:P28496|dip:DIP-4348N|ensemblfungi:YKL008C(gene)|ensemblfungi:YKL008C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0034399"(nuclear periphery)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:0061576"(acyl-CoA ceramide synthase complex)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR013599(TRAM1-like protein)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|reactome:R-SCE-1660661 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:gqRCCAHQcrRAHNO+R2LkQOzJ0mg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:863F6A88D03E464A|rigid:aMBv3x2vRgSkOgiWGaSLGGUaFX8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36088 uniprotkb:P02829 intact:EBI-26738|uniprotkb:D6VXL7|ensemblfungi:YKL069W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:frmsr_yeast(display_long)|uniprotkb:GAF domain-containing protein YKL069W(gene name synonym)|uniprotkb:YKL340(orf name)|uniprotkb:YKL069W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864696 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012854.1|sgd:S000001552|mint:P36088|dip:DIP-4301N|ensemblfungi:YKL069W(gene)|ensemblfungi:YKL069W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0033745"("L-methionine-(R)-S-oxide reductase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070191"(methionine-R-sulfoxide reductase activity)|interpro:IPR000614(Protein of unknown function UPF0067, conserved site)|interpro:IPR003018(GAF)|interpro:IPR029016|rcsb pdb:1F5M|rcsb pdb:3KO6 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:wEMohUS0wAEATyJG3cq62DutTl4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:2E394E5E0DCDAE1D|rigid:a7dxmJP70bh03Go4DJUsnnn2f1Y false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36125 uniprotkb:P02829 intact:EBI-26378|uniprotkb:D6VX95|ensemblfungi:YKR030W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gmh1_yeast(display_long)|uniprotkb:YKR030W(locus name)|uniprotkb:GEA1-6 membrane-associated high-copy suppressor protein 1(gene name synonym)|uniprotkb:GMH1(gene name)|psi-mi:GMH1(display_short)|uniprotkb:MSG1(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864701 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012955.1|sgd:S000001738|mint:P36125|dip:DIP-2023N|ensemblfungi:YKR030W(gene)|ensemblfungi:YKR030W_mRNA(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR007881(UNC-50) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:lmgeWk7CkMQRDAfkDOgwqC9rb/g559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9D8A13061131D76C|rigid:yEMMSPrReJwbHJ+jpWkTUMwyyPI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36137 uniprotkb:P02829 intact:EBI-26427|uniprotkb:D6VXA6|ensemblfungi:YKR044W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:uip5_yeast(display_long)|uniprotkb:YKR044W(locus name)|uniprotkb:UIP5(gene name)|psi-mi:UIP5(display_short)|uniprotkb:ULP1-interacting protein 5(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864706 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001752|refseq:NP_012970.3|dip:DIP-4845N|ensemblfungi:YKR044W(gene)|ensemblfungi:YKR044W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005537"(mannose binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031965"(nuclear membrane)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:IRmbB4FaeCONLvtbK4TEN1B0SYY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A10D9604514C3222|rigid:vxDsmzB2JV2HSSkxuYWc2Y6v3cA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36148 uniprotkb:P02829 intact:EBI-26471|uniprotkb:D6VXC8|ensemblfungi:YKR067W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:gpt2_yeast(display_long)|uniprotkb:YKR067W(locus name)|uniprotkb:GPT2(gene name)|psi-mi:GPT2(display_short)|uniprotkb:GAT1(gene name synonym)|uniprotkb:Dihydroxyacetone phosphate acyltransferase 2(gene name synonym)|uniprotkb:Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 2(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864711 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001775|refseq:NP_012993.3|mint:P36148|dip:DIP-6620N|ensemblfungi:YKR067W(gene)|ensemblfungi:YKR067W_mRNA(transcript)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016287"(glycerone-phosphate O-acyltransferase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:84B9946E56B82F15 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:vHwE5y3AXWOm1SxNz0K3oLTUATI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:4C8BDC8274F11C25|rigid:GdxZu0TlD9Zp8EcwvwwHo+Vmdr8 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07986 uniprotkb:P02829 intact:EBI-37985|uniprotkb:D6VY39|ensemblfungi:YLR036C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yl036_yeast(display_long)|uniprotkb:YLR036C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864716 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004026|refseq:NP_013137.1|dip:DIP-2127N|ensemblfungi:YLR036C(gene)|ensemblfungi:YLR036C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031427 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:GGcRlz7wYc6R9SI/NTywlmxOu8Q559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:3A4335754C451CDE|rigid:9fynrDUZxLpG4Y6s8vdIknI76IA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06058 uniprotkb:P02829 intact:EBI-35851|uniprotkb:D6VZ37|ensemblfungi:YLR404W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:sei1_yeast(display_long)|uniprotkb:SEI1(gene name)|psi-mi:SEI1(display_short)|uniprotkb:FLD1(gene name synonym)|uniprotkb:Few lipid droplets protein 1(gene name synonym)|uniprotkb:YLR404W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864721 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013508.3|sgd:S000004396|mint:Q06058|ensemblfungi:YLR404W(gene)|ensemblfungi:YLR404W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0140042"(lipid droplet formation) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:yvEa8PU4Ra+EvUkIjMt7JaN1Jtw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E95F40D95A0C10F6|rigid:FycFqtaQKq6/Owid8nNvoBF6BTY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03102 uniprotkb:P02829 intact:EBI-27999|uniprotkb:Q6Q5K5|uniprotkb:D6W0F4|ensemblfungi:YML131W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ymn1_yeast(display_long)|uniprotkb:YM4987.04(orf name)|uniprotkb:YML131W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864726 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013575.1|sgd:S000004600|dip:DIP-5615N|mint:Q03102|ensemblfungi:YML131W(gene)|ensemblfungi:YML131W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR036291|interpro:IPR041694 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:NabcVcC5Qntd63WaiAZ1sLC+MF8559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:731961C644582A3B|rigid:iQ/Ade6Y90jFCp05R6AA2KbYht4 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38363 uniprotkb:P02829 intact:EBI-4963|uniprotkb:D6VQU7|refseq:NP_009861|dip:DIP-28099N intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:cos2_yeast(display_long)|uniprotkb:COS2(gene name)|psi-mi:COS2(display_short)|uniprotkb:YBR302C(locus name)|uniprotkb:YBR2121(orf name)|uniprotkb:COS3(gene name)|psi-mi:COS3(display_short)|uniprotkb:YML132W(locus name)|uniprotkb:YM4987.03(orf name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864731 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane)|sgd:S000000506(COS2)|sgd:S000004601(COS3)|interpro:IPR001142(Yeast membrane protein DUP)|cygd:YBR302c|go:"GO:0005624"(obsolete membrane fraction)|go:"GO:0005515"(protein binding)|go:"GO:0006883"(cellular sodium ion homeostasis)|refseq:NP_009861.1|refseq:NP_013574.1|uniprotkb:P38363(uniprot-removed-ac) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:vVTRRs88DZ2o3gXfPOYXImMkYYg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:84F33CF48BF32DB5|rigid:oFyyNSHy2LabMNgrW9WM71a+T9U false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03818 uniprotkb:P02829 intact:EBI-27344|uniprotkb:D6VZY1|ensemblfungi:YMR159C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:atg16_yeast(display_long)|uniprotkb:Cytoplasm to vacuole targeting protein 11(gene name synonym)|uniprotkb:SAP18 homolog(gene name synonym)|uniprotkb:YMR159C(locus name)|uniprotkb:YM8520.08C(orf name)|uniprotkb:ATG16(gene name)|psi-mi:ATG16(display_short)|uniprotkb:APG15(gene name synonym)|uniprotkb:APG16(gene name synonym)|uniprotkb:CVT11(gene name synonym)|uniprotkb:SAP18(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864736 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013882.1|sgd:S000004769|dip:DIP-2144N|mint:Q03818|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905037"(autophagosome organization)|interpro:IPR013923(Autophagy protein 16)|rcsb pdb:2DYM|rcsb pdb:2DYO|rcsb pdb:3A7O|rcsb pdb:3A7P|rcsb pdb:3W1S|ensemblfungi:YMR159C(gene)|ensemblfungi:YMR159C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:6D4308298D4DBB59 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:bmw05AxBAI+DZmzlMNmib4F/epw559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6022222DBF87AAB6|rigid:k24GQmRfWzKnrVwKhMB11OHGisU false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50945 uniprotkb:P02829 intact:EBI-28819|uniprotkb:Q45U03|uniprotkb:D6W179|ensemblfungi:YNL100W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mic27_yeast(display_long)|uniprotkb:MIC27(gene name)|psi-mi:MIC27(display_short)|uniprotkb:AIM37(gene name synonym)|uniprotkb:Altered inheritance of mitochondria protein 37(gene name synonym)|uniprotkb:MCS27(gene name synonym)|uniprotkb:Mitochondrial contact site complex 27 kDa subunit(gene name synonym)|uniprotkb:N2190(orf name)|uniprotkb:YNL100W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864741 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005044|refseq:NP_014299.1|dip:DIP-2042N|ensemblfungi:YNL100W(gene)|ensemblfungi:YNL100W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0044284"(mitochondrial crista junction)|go:"GO:0061617"(MICOS complex) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:bUm4Do7VElQHLugYd5vAF7Whgoc559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:BC2EFB9C21350B1C|rigid:I1svpVY5a1A5MCojSdBGizDggDI false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40169 uniprotkb:P02829 intact:EBI-29087|uniprotkb:D6W0Z3|ensemblfungi:YNL194C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:ynt4_yeast(display_long)|uniprotkb:N1394(orf name)|uniprotkb:YNL194C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864746 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014205.1|sgd:S000005138|dip:DIP-4465N|ensemblfungi:YNL194C(gene)|ensemblfungi:YNL194C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030437"(ascospore formation)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0032185"(septin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:b33342jPeMY4Ezvcp2r9vV26U4o559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:ABA8C82FA1F35106|rigid:yyYf1ry19IeDqPzWm9NHEetn77w false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42836 uniprotkb:P02829 intact:EBI-28414|uniprotkb:D6W0M1|ensemblfungi:YNL326C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pfa3_yeast(display_long)|uniprotkb:YNL326C(locus name)|uniprotkb:N0325(orf name)|uniprotkb:PFA3(gene name)|psi-mi:PFA3(display_short)|uniprotkb:Protein fatty acyltransferase 3(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864751 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014073.1|sgd:S000005270|dip:DIP-4833N|ensemblfungi:YNL326C(gene)|ensemblfungi:YNL326C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001594(Zinc finger, DHHC-type) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:wDUIzJoLnfaV6fo96hca+beyKb4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:077DC57826623749|rigid:CEm87fjRtgRB7cb7ITkQ0gx+u38 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08176 uniprotkb:P02829 intact:EBI-31062|uniprotkb:D6W239|ensemblfungi:YOL026C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:mim1_yeast(display_long)|uniprotkb:Mitochondrial 13 kDa outer membrane protein(gene name synonym)|uniprotkb:MIM1(gene name)|psi-mi:MIM1(display_short)|uniprotkb:TOM13(gene name synonym)|uniprotkb:YOL026C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864756 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014616.1|sgd:S000005386|interpro:IPR013262(Outer membrane protein, MIM1/TOM13, mitochondrial)|mint:Q08176|ensemblfungi:YOL026C(gene)|ensemblfungi:YOL026C_mRNA(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070096"(mitochondrial outer membrane translocase complex assembly) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:WQVjFbpO1VhMiQOyfj4h3M583yY559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:5CB0093BE06ACB6B|rigid:6/3kMz59O2S5R9NqeOrUZ2jeo/g false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12274 uniprotkb:P02829 intact:EBI-33978|uniprotkb:D6W2F8|ensemblfungi:YOR097C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yor97_yeast(display_long)|uniprotkb:YOR3180c(orf name)|uniprotkb:YOR097C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864761 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005623|refseq:NP_014740.1|mint:Q12274|dip:DIP-4113N|ensemblfungi:YOR097C(gene)|ensemblfungi:YOR097C_mRNA(transcript)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:cSNgcUy7NcRe/0214gbEpK8fVHQ559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:0018555E2DD08282|rigid:KJXhwMI7udaaqay6ZZsXVlDRPAA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02606 uniprotkb:P02829 intact:EBI-37142|uniprotkb:D6W3Z8|ensemblfungi:YPL014W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp014_yeast(display_long)|uniprotkb:YPL014W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864766 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005935|refseq:NP_015311.1|dip:DIP-2703N|ensemblfungi:YPL014W(gene)|ensemblfungi:YPL014W_mRNA(transcript)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:cMdt9CBnLZGfI7GmVmp3iq+eLDE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9E3DE929B5C64E0D|rigid:mR5H4AAvsIFtio0o23+1us2ZTHA false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02981 uniprotkb:P02829 intact:EBI-29353|uniprotkb:D6W3Q8|ensemblfungi:YPL109C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp109_yeast(display_long)|uniprotkb:LPH17C(orf name)|uniprotkb:YPL109C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864771 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015216.3|sgd:S000006030|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044095|ensemblfungi:YPL109C(gene)|ensemblfungi:YPL109C_mRNA(transcript)|go:"GO:0005739"(mitochondrion) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:Y/RW4KU1n9m0Ug5U4d+2jgh8lRo559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:9DB12BCABC755C2B|rigid:6S/VXCLKIWvmUOMwrglDxAniFwc false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12498 uniprotkb:P02829 intact:EBI-32462|uniprotkb:D6W3L2|ensemblfungi:YPL156C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:prm4_yeast(display_long)|uniprotkb:PRM4(gene name)|psi-mi:PRM4(display_short)|uniprotkb:P2578(orf name)|uniprotkb:YPL156C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864776 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015169.1|sgd:S000006077|dip:DIP-5502N|ensemblfungi:YPL156C(gene)|ensemblfungi:YPL156C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0016021"(integral component of membrane) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:OJ+181kdGzPOprifGMB9foL2hP4559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:91ED77AB86CEE32A|rigid:GL4l6murdC72H2Yhs1LUY17yLOE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06892 uniprotkb:P02829 intact:EBI-13701|uniprotkb:Q08928|uniprotkb:D6W3I1|ensemblfungi:YPL188W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:pos5_yeast(display_long)|uniprotkb:POS5(gene name)|psi-mi:POS5(display_short)|uniprotkb:YPL188W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864781 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006109|refseq:NP_015136.1|ensemblfungi:YPL188W(gene)|ensemblfungi:YPL188W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|rcsb pdb:3AFO|dip:DIP-5503N ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:4n8TcpxeCYBUCHDHMqmxXeNsiGg559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:107C87FF510BEED7|rigid:npbePLleDCvFnMx44lduSrjBtVY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08954 uniprotkb:P02829 intact:EBI-33103|uniprotkb:D6W3H0|ensemblfungi:YPL199C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp199_yeast(display_long)|uniprotkb:YPL199C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864786 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015125.1|sgd:S000006120|interpro:IPR013899(Region of unknown function DUF1771)|interpro:IPR002625(Smr protein/MutS2 C-terminal)|mint:Q08954|interpro:IPR036063|ensemblfungi:YPL199C(gene)|ensemblfungi:YPL199C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0071944"(cell periphery) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:lmKmC6NfmtZ61GCNuCxF1wOWIl0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:A38F86BBB6755DFC|rigid:y4DmM98pFUSkPtEU1psKofSsnSg false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12270 uniprotkb:P02829 intact:EBI-31471|uniprotkb:D6W3C5|ensemblfungi:YPL246C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:rbd2_yeast(display_long)|uniprotkb:RBD2(gene name)|psi-mi:RBD2(display_short)|uniprotkb:YPL246C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864791 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015078.1|sgd:S000006167|dip:DIP-1734N|mint:Q12270|ensemblfungi:YPL246C(gene)|ensemblfungi:YPL246C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|interpro:IPR022764|interpro:IPR035952 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:oj6WhiFipqOLt2YiBpFitgJLeA0559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:D842C379BEE2D137|rigid:tNCiU5P9WrtvE1EGMCjFIBZeAvE false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08974 uniprotkb:P02829 intact:EBI-35564|uniprotkb:D6W3B4|ensemblfungi:YPL257W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp257_yeast(display_long)|uniprotkb:YPL257W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864796 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006178|refseq:NP_015066.1|dip:DIP-5352N|ensemblfungi:YPL257W(gene)|ensemblfungi:YPL257W_mRNA(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031427 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:XCGZ1/tGsPuyf+/Xw6zaXlyfRTE559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:02DBAA98A5BCC4D5|rigid:uliG8Ei/pgtDnHfNlbjtBL6Noxw false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13585 uniprotkb:P02829 intact:EBI-33008|intact:EBI-37305|uniprotkb:Q86ZS6|uniprotkb:D6W490|ensemblfungi:YPR089W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp089_yeast(display_long)|uniprotkb:YPR090W(orf name)|uniprotkb:YPR089W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864801 author score:3 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015414.2|sgd:S000006293|dip:DIP-34618N|ensemblfungi:YPR089W(gene)|ensemblfungi:YPR089W_mRNA(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0051020"(GTPase binding)|interpro:IPR002710(Dilute)|interpro:IPR036770|interpro:IPR037986 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:jueoYQ5eZgwmGWB02jCOsXQH7uo559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:67AB49E611852DAE|rigid:lLS1d0VlLMJxyqjpDTx7fIooYl0 false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06108 uniprotkb:P02829 intact:EBI-38709|uniprotkb:D6W4B4|ensemblfungi:YPR115W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:rgc1_yeast(display_long)|uniprotkb:RGC1(gene name)|psi-mi:RGC1(display_short)|uniprotkb:YPR115W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864806 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015440.1|sgd:S000006319|mint:Q06108|dip:DIP-1970N|ensemblfungi:YPR115W(gene)|ensemblfungi:YPR115W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016247"(channel regulator activity)|go:"GO:0090372"(positive regulation of glycerol transport)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR027267 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - crc64:28D63D32843BFE08 crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:xmUSFR/ZbsZ8vxzuwd0fOTQOzBI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:5615A498E5F20AFD|rigid:F6iLHoznXzTMEzxU/47rIt13eKY false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06494 uniprotkb:P02829 intact:EBI-35142|uniprotkb:D6W4C4|ensemblfungi:YPR127W intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:plr1_yeast(display_long)|uniprotkb:YPR127W(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864811 author score:2 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015452.1|sgd:S000006331|interpro:IPR023210|interpro:IPR036812|ensemblfungi:YPR127W(gene)|ensemblfungi:YPR127W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0042820"(vitamin B6 catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050236"("pyridoxine:NADP 4-dehydrogenase activity") ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:rbmC2ZzErDBskCFZRBqUgeI0xAM559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:E36DCA23C1C821EE|rigid:aVV48CzvNxxvvMSFMJX0zPBNDTs false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06523 uniprotkb:P02829 intact:EBI-33312|uniprotkb:D6W4E5|ensemblfungi:YPR148C intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:yp148_yeast(display_long)|uniprotkb:YPR148C(locus name) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Millson et al. (2005) pubmed:15879519 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-864816 author score:1 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015474.1|sgd:S000006352|dip:DIP-3808N|ensemblfungi:YPR148C(gene)|ensemblfungi:YPR148C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR018859|interpro:IPR027267 ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N - - crc64:D7C35676D668FB63 - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/20 2014/10/16 rogid:OvYsZcwg3M59zGlWX9ZCOZg/TuI559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 intact-crc:6CEB4E36BB2D1ABA|rigid:NMDK5w1H+8OYjUS2rLXbQDNp3bs false - mutation increasing interaction:33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)