#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95229 uniprotkb:Q9H081 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:Q8NBT2 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:Q8NG31 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:Q9H410 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:O14777 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:O15182 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-712959|ensembl:ENSP00000283122|uniprotkb:Q53YD2|uniprotkb:Q9BS23 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:cetn3_human(display_long)|uniprotkb:CETN3(gene name)|psi-mi:CETN3(display_short)|uniprotkb:CEN3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 ensembl:ENST00000283122(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|ensembl:ENSG00000153140(gene)|go:"GO:0051301"(cell division)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_004356.2|refseq:NP_001284697.1 - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:m0uBq6ZNOxGDC2kU8i8rDRlVS6s9606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O95229 uniprotkb:Q6P1K2 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001131|imex:IM-19320-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 intact-crc:1D4D6B2E8F024B22|rigid:bUkWygeQpVuI6D30Oa8u9HaoS4Y false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O43264 uniprotkb:P50748 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-1001245|uniprotkb:B3KSG2|uniprotkb:A7E2C4|ensembl:ENSP00000328236 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:kntc1_human(display_long)|uniprotkb:Rough deal homolog(gene name synonym)|uniprotkb:KNTC1(gene name)|psi-mi:KNTC1(display_short)|uniprotkb:KIAA0166(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001216|imex:IM-19320-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_055523.1|ensembl:ENSG00000184445(gene)|ensembl:ENST00000333479(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990423"(RZZ complex)|interpro:IPR019527|interpro:IPR036322|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_006719769.1|dip:DIP-36479N - - - figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:Fzk1xgK9pVFUAlEHLG3L35X0scU9606 intact-crc:D2852D7ED3CF6307|rigid:synmb/kZitD5bxs8ClGkjVRGmEs false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O43264 uniprotkb:Q9H900 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-1001239|uniprotkb:Q6N049|uniprotkb:Q96SY7|uniprotkb:Q9NWG7|uniprotkb:Q8N404|uniprotkb:B3KVB8|ensembl:ENSP00000311429 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:zwilc_human(display_long)|uniprotkb:ZWILCH(gene name)|psi-mi:ZWILCH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001216|imex:IM-19320-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_060445.3|refseq:NP_001274750.1|refseq:NP_001274751.1|refseq:NP_001274752.1|dip:DIP-36478N|ensembl:ENSG00000174442(gene)|ensembl:ENST00000307897(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:1990423"(RZZ complex)|interpro:IPR018630|rcsb pdb:3IF8|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:pIk5I4Y9Qk7AxO0KhWURdlvUu/Y9606 intact-crc:D2852D7ED3CF6307|rigid:synmb/kZitD5bxs8ClGkjVRGmEs false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O43264 uniprotkb:Q9UFG5 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-741214|intact:EBI-28979499|ensembl:ENSP00000397394|ensembl:ENSP00000466372|ensembl:ENSP00000467861|ensembl:ENSP00000468688|uniprotkb:Q8N9R7|uniprotkb:Q8WV94|uniprotkb:B3KQN6|intact:EBI-2561342 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:cs025_human(display_long)|uniprotkb:C19orf25(gene name)|psi-mi:C19orf25(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001216|imex:IM-19320-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_689695.2|ensembl:ENSG00000119559(gene)|ensembl:ENST00000436106(transcript)|ensembl:ENST00000585675(transcript)|ensembl:ENST00000586564(transcript)|ensembl:ENST00000592872(transcript)|interpro:IPR028227|ensembl:ENSP00000397394|ensembl:ENSP00000468688|ensembl:ENSP00000466372|ensembl:ENSP00000467861|refseq:XP_006722716.1|refseq:XP_005259563.1 - - - figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:8x4kfH5+Et/gOjw93ulVXPlAync9606 intact-crc:D2852D7ED3CF6307|rigid:synmb/kZitD5bxs8ClGkjVRGmEs false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O43264 uniprotkb:Q6NUQ1 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-726876|uniprotkb:Q75MG9|uniprotkb:Q75MH0|uniprotkb:Q96IW8|uniprotkb:Q9H229|uniprotkb:Q9HAD9|intact:EBI-28981798|ensembl:ENSP00000257700 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:rint1_human(display_long)|uniprotkb:RAD50 interactor 1(gene name synonym)|uniprotkb:RINT1(gene name)|psi-mi:RINT1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001216|imex:IM-19320-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N ensembl:ENSG00000135249(gene)|ensembl:ENST00000257700(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0015031"(protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070939"(Dsl1/NZR complex)|interpro:IPR007528(RINT-1/TIP-1)|interpro:IPR042044|reactome:R-HSA-6811434|refseq:NP_068749.3|ensembl:ENSP00000257700|dip:DIP-36477N - - - figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:aUzUSBI8f6ednxeVnP97ifOMoPc9606 intact-crc:D2852D7ED3CF6307|rigid:synmb/kZitD5bxs8ClGkjVRGmEs false calmodulin binding peptide plus protein a tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:O43264 uniprotkb:O95229 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001272|imex:IM-19320-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 intact-crc:A26BCB2EF21E11D9|rigid:C+KKZrwfb6v2/lX4mg4toGSwTpk false - calmodulin binding peptide plus protein a tag:n-n - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O95229 uniprotkb:O43264 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001292|imex:IM-19320-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N - - - figure legend:Fig. 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 intact-crc:5E0B6C269C5B6707|rigid:C+KKZrwfb6v2/lX4mg4toGSwTpk false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O43264 uniprotkb:Q9Y6D9 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001430|imex:IM-19320-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N - - - figure legend:Fig. 7B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606 intact-crc:A674316E419C36F0|rigid:XUbMVcguvzRsmI1i8RwcOVmrNRo false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O43264 uniprotkb:O43683 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-748936|uniprotkb:O43430|uniprotkb:O43643|uniprotkb:O60626|uniprotkb:Q53QE4|intact:EBI-10974242|uniprotkb:E9PC26|uniprotkb:F5GXI5|intact:EBI-28974347|ensembl:ENSP00000302530 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:bub1_human(display_long)|uniprotkb:BUB1A(gene name synonym)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short)|uniprotkb:BUB1L(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001434|imex:IM-19320-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N ensembl:ENSP00000302530|ensembl:ENST00000409311|ensembl:ENSP00000386701|ensembl:ENST00000535254|ensembl:ENSP00000441013|refseq:NP_004327.1|refseq:NP_001265546.1|ensembl:ENSG00000169679(gene)|ensembl:ENST00000302759(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007063"(regulation of sister chromatid cohesion)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43683|rcsb pdb:2LAH|rcsb pdb:4A1G|rcsb pdb:4QPM|rcsb pdb:4R8Q|rcsb pdb:5DMZ|rcsb pdb:6F7B|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-24206N - - - figure legend:Fig. 7D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:hsbJZRz5kXxVI+ADgSaCoUfXE1o9606 intact-crc:5F54320F9FA17063|rigid:HD/f4YhJYWMfob1lGYdCoZz346g false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O60566 uniprotkb:O43264 intact:EBI-1001438|uniprotkb:B2R6U0|uniprotkb:B4DL09|uniprotkb:B4DLG3|uniprotkb:Q59HH6|uniprotkb:Q8WV50|intact:EBI-2551047|uniprotkb:O60501|uniprotkb:O60627|uniprotkb:O60758|uniprotkb:O75389|uniprotkb:Q96KM4|ensembl:ENSP00000287598 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 psi-mi:bub1b_human(display_long)|uniprotkb:MAD3/BUB1-related protein kinase(gene name synonym)|uniprotkb:Mitotic checkpoint kinase MAD3L(gene name synonym)|uniprotkb:SSK1(gene name synonym)|uniprotkb:BUB1B(gene name)|psi-mi:BUB1B(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:MAD3L(gene name synonym)|uniprotkb:Protein SSK1(gene name synonym) psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001465|imex:IM-19320-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001202.4|dip:DIP-24203N|ensembl:ENSG00000156970(gene)|ensembl:ENST00000287598(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR011009(Protein kinase-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|mint:O60566|rcsb pdb:2WVI|rcsb pdb:3SI5|rcsb pdb:4GGD|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:5SWF|rcsb pdb:6TLJ|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N - - - figure legend:Fig. 7F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:EgsQ2ZywEJ+r8hd95vcNEyikMBA9606 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 intact-crc:3CC9EA7BE14283EE|rigid:Bzg1JJqD+bJk+unnFWN03xBqvGY false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O43264 uniprotkb:O14576 intact:EBI-1001217|ensembl:ENSP00000200135|uniprotkb:A1A528 intact:EBI-366267|uniprotkb:Q9Y2X1|intact:EBI-747976|uniprotkb:B4DME3|uniprotkb:F5H050|uniprotkb:G5E9K1|uniprotkb:Q8TBF7|ensembl:ENSP00000320130 psi-mi:zw10_human(display_long)|uniprotkb:ZW10(gene name)|psi-mi:ZW10(display_short) psi-mi:dc1i1_human(display_long)|uniprotkb:DYNC1I1(gene name)|psi-mi:DYNC1I1(display_short)|uniprotkb:DNCIC1(gene name synonym)|uniprotkb:Cytoplasmic dynein intermediate chain 1(gene name synonym)|uniprotkb:Dynein intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:DNCI1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001469|imex:IM-19320-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004715.1|ensembl:ENSG00000086827(gene)|ensembl:ENST00000200135(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O43264|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6811434|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-36471N refseq:NP_001129028.1|refseq:NP_001129029.1|refseq:NP_004402.1|refseq:XP_011514163.1|refseq:XP_011514164.1|refseq:NP_001265350.1|refseq:NP_001265351.1|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:O14576|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-2500257|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-3371497|ensembl:ENSG00000158560(gene)|ensembl:ENST00000324972(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|refseq:XP_016867293.1|refseq:XP_016867294.1 - - - figure legend:Fig. 7A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/08/29 2014/10/16 rogid:yqOV+ZYOLEPClJbYtPp9Jvlhyvc9606 rogid:Hw0CFWl7NZ1lMObYmGYYcH+J1Xw9606 intact-crc:CA67546F0A96FE9D|rigid:I6JVIZP8Z+YcYqbUD9HBlc+Hxes false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8JGT8 uniprotkb:Q498I0 intact:EBI-1001411 intact:EBI-1001308 psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:q498i0_xenla(display_long)|uniprotkb:zw10.L(gene name)|psi-mi:zw10.L(display_short)|uniprotkb:LOC445850(gene name synonym)|uniprotkb:zw10(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001307|imex:IM-19320-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) refseq:NP_001086431.1|interpro:IPR009361(Centromerekinetochore Zw10)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|go:"GO:0140483"(kinetochore adaptor activity) - - - figure legend:Fig. 3E, 5A, 5E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 rogid:esR8Q213OEfMYZdXVH+i1/3X7gA8355 intact-crc:E5D9E495A604B58E|rigid:bNerWUFu/tblaRfVgQpT/qTHDoM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) intact:EBI-1003888 uniprotkb:Q8JGT8 - intact:EBI-1001411 psi-mi:kntc1_xenla(display_short)|psi-mi:EBI-1003888(display_long) psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001330|imex:IM-19320-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ddbj/embl/genbank:BJ068773(primary-reference) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) - no-uniprot-update:An amino acid sequence which is not represented in UniProt - figure legend:Fig. 3E, 5A, 5E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:2ri0IZHNyKcAYVwHjAG1NacvAGA8355 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 intact-crc:5B9806E7010529D3|rigid:igMyTPMLyowxarutzDl3HI3ZC7Y false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8JGT8 uniprotkb:Q6GPD1 intact:EBI-1001411 intact:EBI-1001368 psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:q6gpd1_xenla(display_long)|uniprotkb:mad1l1.L(gene name)|psi-mi:mad1l1.L(display_short)|uniprotkb:Xmad1(gene name synonym)|uniprotkb:mad1-A(gene name synonym)|uniprotkb:mad1l1(gene name synonym)|uniprotkb:XELAEV_18045235mg(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001373|imex:IM-19320-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) interpro:IPR008672(Mitotic checkpoint)|refseq:NP_001080972.1|go:"GO:0005634"(nucleus)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|refseq:XP_018089610.1 - - - figure legend:Fig. 5|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 rogid:mLB9zxj5o2WZ2zj7JQVbQiJJEP48355 intact-crc:F1F03FAC7D380354|rigid:gF14I3kfDNVJT+e6S0amWEQF9aM false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8JGT8 uniprotkb:P79935 intact:EBI-1001411 intact:EBI-1001377 psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:p79935_xenla(display_long)|uniprotkb:mad2l1.S(gene name)|psi-mi:mad2l1.S(display_short)|uniprotkb:mad2l1(gene name synonym)|uniprotkb:XELAEV_18009381mg(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001381|imex:IM-19320-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) interpro:IPR003511(DNA-binding HORMA)|refseq:NP_001080741.1|interpro:IPR036570 - - - figure legend:Fig. 5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 rogid:3XaL2pXCvgJzsN5I8Z2MNW3zN8Y8355 intact-crc:508DDDF45E48B335|rigid:nik9rtxKwNFovWGjlin8Mbq4oJ8 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8JGT8 uniprotkb:Q91636 intact:EBI-1001411 intact:EBI-1001385|uniprotkb:Q5D0B4 psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:kif2c_xenla(display_long)|uniprotkb:Kinesin central motor 1(gene name synonym)|uniprotkb:kif2c(gene name)|psi-mi:kif2c(display_short)|uniprotkb:kcm1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001390|imex:IM-19320-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|refseq:NP_001080314.1|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990939"|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961 - - - figure legend:Fig. 5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 rogid:lNNxPMeNYqDnz9MMFccpmcXuEuc8355 intact-crc:4876EA8D993A6DC8|rigid:f+uaDGw0Vu2N3F1X0edmNuZt2Po false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8JGT8 uniprotkb:Q569M3 intact:EBI-1001411 intact:EBI-1001394 psi-mi:q8jgt8_xenla(display_long)|uniprotkb:bub1b.L(gene name)|psi-mi:bub1b.L(display_short)|uniprotkb:BUBR1(gene name synonym)|uniprotkb:bub1b(gene name synonym) psi-mi:cenpa_xenla(display_long)|uniprotkb:cenpa(gene name)|psi-mi:cenpa(display_short)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1001407|imex:IM-19320-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|refseq:NP_001079357.1|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling) refseq:NP_001090007.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|go:"GO:0000776"(kinetochore)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity) - - - figure legend:Fig. 5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2006/08/29 2014/10/16 rogid:tALxHrKmJBukr28/i6LXqtZjVFU8355 rogid:VKXiWdMMc5aqd8vEBiEJhRhbqcs8355 intact-crc:567F17CACE2507D9|rigid:nBKnh5psppL7hzDfjdDA2YIex5s false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q498I0 intact:EBI-1003888 intact:EBI-1001308 - psi-mi:q498i0_xenla(display_long)|uniprotkb:zw10.L(gene name)|psi-mi:zw10.L(display_short)|uniprotkb:LOC445850(gene name synonym)|uniprotkb:zw10(gene name synonym) psi-mi:kntc1_xenla(display_short)|psi-mi:EBI-1003888(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001362|imex:IM-19320-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001086431.1|interpro:IPR009361(Centromerekinetochore Zw10)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|go:"GO:0140483"(kinetochore adaptor activity) ddbj/embl/genbank:BJ068773(primary-reference) - - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2006/08/29 2014/10/16 rogid:esR8Q213OEfMYZdXVH+i1/3X7gA8355 rogid:2ri0IZHNyKcAYVwHjAG1NacvAGA8355 intact-crc:716CF6DDAA552E5B|rigid:uLQObl0eCEl725OwjaM8iFhJo0k false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q498I0 intact:EBI-1003888 intact:EBI-1001308 - psi-mi:q498i0_xenla(display_long)|uniprotkb:zw10.L(gene name)|psi-mi:zw10.L(display_short)|uniprotkb:LOC445850(gene name synonym)|uniprotkb:zw10(gene name synonym) psi-mi:kntc1_xenla(display_short)|psi-mi:EBI-1003888(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kops et al. (2005) pubmed:15824131|imex:IM-19320 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1001366|imex:IM-19320-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001086431.1|interpro:IPR009361(Centromerekinetochore Zw10)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007093"(mitotic cell cycle checkpoint signaling)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051301"(cell division)|go:"GO:0140483"(kinetochore adaptor activity) ddbj/embl/genbank:BJ068773(primary-reference) - - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla-oocyte)|taxid:8355(Xenopus laevis) - 2006/08/29 2014/10/16 rogid:esR8Q213OEfMYZdXVH+i1/3X7gA8355 rogid:2ri0IZHNyKcAYVwHjAG1NacvAGA8355 intact-crc:A354B1101FDF6259|rigid:uLQObl0eCEl725OwjaM8iFhJo0k false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)