#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03267 uniprotkb:P63166 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-80152|uniprotkb:P55856|uniprotkb:Q3TX92|uniprotkb:Q93068|ensembl:ENSMUSP00000088935 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:sumo1_mouse(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short)|uniprotkb:Smt3c(gene name synonym)|uniprotkb:Smt3h3(gene name synonym)|uniprotkb:Ubl1(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908619|imex:IM-18899-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_033486.1|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-877312|reactome:R-MMU-8866904|reactome:R-MMU-9615933|ensembl:ENSMUSG00000026021(gene)|ensembl:ENSMUST00000091374(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0001741"(XY body)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|reactome:R-MMU-3065676|reactome:R-MMU-3065678|reactome:R-MMU-3065679|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|reactome:R-MMU-4615885|reactome:R-MMU-4655427|dip:DIP-29278N - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10090 intact-crc:2B2BD99D26588E7D|rigid:gEcNpgRQ67cMeLrPjIslM+v79K8 false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63166 uniprotkb:O08900 intact:EBI-80152|uniprotkb:P55856|uniprotkb:Q3TX92|uniprotkb:Q93068|ensembl:ENSMUSP00000088935 intact:EBI-908654|uniprotkb:B1AQE6|ensembl:ENSMUSP00000099430 psi-mi:sumo1_mouse(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short)|uniprotkb:Smt3c(gene name synonym)|uniprotkb:Smt3h3(gene name synonym)|uniprotkb:Ubl1(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) psi-mi:ikzf3_mouse(display_long)|uniprotkb:Ikzf3(gene name)|psi-mi:Ikzf3(display_short)|uniprotkb:Zfpn1a3(gene name synonym)|uniprotkb:Znfn1a3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908661|imex:IM-18899-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033486.1|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-877312|reactome:R-MMU-8866904|reactome:R-MMU-9615933|ensembl:ENSMUSG00000026021(gene)|ensembl:ENSMUST00000091374(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0001741"(XY body)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|reactome:R-MMU-3065676|reactome:R-MMU-3065678|reactome:R-MMU-3065679|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|reactome:R-MMU-4615885|reactome:R-MMU-4655427|dip:DIP-29278N refseq:NP_035901.1|ensembl:ENSMUSG00000018168(gene)|ensembl:ENSMUST00000103141(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10090 rogid:QK7ed3XZmYFmbIoH9uJWjXWlpy010090 intact-crc:C0703C82EF7EC963|rigid:9DRsfns5kuIiihEaslDKlUnq1R8 false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03267 uniprotkb:Q9Z1F9 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-908714|uniprotkb:Q3TQN3|uniprotkb:Q3U819|uniprotkb:Q3U9J5|uniprotkb:Q8BVX9|ensembl:ENSMUSP00000099807 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:sae2_mouse(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:Uble1b(gene name synonym)|uniprotkb:Sae2(gene name synonym)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908729|imex:IM-18899-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_057891.1|ensembl:ENSMUSG00000052997(gene)|ensembl:ENSMUST00000102746(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9Z1F9|reactome:R-MMU-3065676|reactome:R-MMU-3065678 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:yv0wnr16uxg3qqgJzX8BroA6stY10090 intact-crc:103BF012868C73C0|rigid:Z6wjCMbmJzQ3HiGiuCUkfuU1Xe8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z1F9 uniprotkb:O08900 intact:EBI-908714|uniprotkb:Q3TQN3|uniprotkb:Q3U819|uniprotkb:Q3U9J5|uniprotkb:Q8BVX9|ensembl:ENSMUSP00000099807 intact:EBI-908654|uniprotkb:B1AQE6|ensembl:ENSMUSP00000099430 psi-mi:sae2_mouse(display_long)|uniprotkb:Uba2(gene name)|psi-mi:Uba2(display_short)|uniprotkb:Uble1b(gene name synonym)|uniprotkb:Sae2(gene name synonym)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym) psi-mi:ikzf3_mouse(display_long)|uniprotkb:Ikzf3(gene name)|psi-mi:Ikzf3(display_short)|uniprotkb:Zfpn1a3(gene name synonym)|uniprotkb:Znfn1a3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908733|imex:IM-18899-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057891.1|ensembl:ENSMUSG00000052997(gene)|ensembl:ENSMUST00000102746(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9Z1F9|reactome:R-MMU-3065676|reactome:R-MMU-3065678 refseq:NP_035901.1|ensembl:ENSMUSG00000018168(gene)|ensembl:ENSMUST00000103141(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:yv0wnr16uxg3qqgJzX8BroA6stY10090 rogid:QK7ed3XZmYFmbIoH9uJWjXWlpy010090 intact-crc:90725D8665CCD5C1|rigid:QKaYJYwt9uk91uPX3SEfDtbFPN0 false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P63280 uniprotkb:O08900 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 intact:EBI-908654|uniprotkb:B1AQE6|ensembl:ENSMUSP00000099430 psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:ikzf3_mouse(display_long)|uniprotkb:Ikzf3(gene name)|psi-mi:Ikzf3(display_short)|uniprotkb:Zfpn1a3(gene name synonym)|uniprotkb:Znfn1a3(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908754|imex:IM-18899-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N refseq:NP_035901.1|ensembl:ENSMUSG00000018168(gene)|ensembl:ENSMUST00000103141(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009617"(response to bacterium)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 rogid:QK7ed3XZmYFmbIoH9uJWjXWlpy010090 intact-crc:9FD2921678EFFE56|rigid:Ri8C9Kuv2ZuzTzdyMUPZAygdgug false - sufficient binding region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03267 uniprotkb:P63280 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-80180|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q6RUT3|uniprotkb:Q86VB3|ensembl:ENSMUSP00000055714|ensembl:ENSMUSP00000134169|ensembl:ENSMUSP00000134261|ensembl:ENSMUSP00000134350|ensembl:ENSMUSP00000134450|ensembl:ENSMUSP00000134491 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:ubc9_mouse(display_long)|uniprotkb:Ube2i(gene name)|psi-mi:Ube2i(display_short)|uniprotkb:Ubc9(gene name synonym)|uniprotkb:Ubce9(gene name synonym)|uniprotkb:Ubce2i(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908758|imex:IM-18899-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_001171080.1|refseq:NP_001171081.1|refseq:NP_035795.1|ensembl:ENSMUSG00000015120(gene)|ensembl:ENSMUST00000049911(transcript)|ensembl:ENSMUST00000172618(transcript)|ensembl:ENSMUST00000173084(transcript)|ensembl:ENSMUST00000173713(transcript)|ensembl:ENSMUST00000174001(transcript)|ensembl:ENSMUST00000174031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990234"(transferase complex)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63280|rcsb pdb:1U9A|rcsb pdb:1U9B|rcsb pdb:2UYZ|rcsb pdb:2VRR|reactome:R-MMU-196791|reactome:R-MMU-3065678|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-4655427|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-8866904|reactome:R-MMU-9615933|refseq:XP_006524111.1|refseq:XP_006524112.1|dip:DIP-29276N - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo10090 intact-crc:59B14DE544521C5F|rigid:XKovXVdBvlG2/PENgkjEXZQmwt4 false sufficient binding region:1-141 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03267 uniprotkb:P63166 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-80152|uniprotkb:P55856|uniprotkb:Q3TX92|uniprotkb:Q93068|ensembl:ENSMUSP00000088935 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:sumo1_mouse(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short)|uniprotkb:Smt3c(gene name synonym)|uniprotkb:Smt3h3(gene name synonym)|uniprotkb:Ubl1(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-908810|imex:IM-18899-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_033486.1|reactome:R-MMU-4755510|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-5696395|reactome:R-MMU-69473|reactome:R-MMU-877312|reactome:R-MMU-8866904|reactome:R-MMU-9615933|ensembl:ENSMUSG00000026021(gene)|ensembl:ENSMUST00000091374(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0001741"(XY body)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|reactome:R-MMU-3065676|reactome:R-MMU-3065678|reactome:R-MMU-3065679|reactome:R-MMU-3108214|reactome:R-MMU-3108232|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4085377|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-4570464|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|reactome:R-MMU-4615885|reactome:R-MMU-4655427|dip:DIP-29278N - - - antagonist:Isopeptidase Senp1|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10090 intact-crc:23538E4511E5D647|rigid:gEcNpgRQ67cMeLrPjIslM+v79K8 false sumoylated lysine:58-58,240-240|sumoylated lysine:58-58|sumoylated lysine:240-240 green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:O54714 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-927993|imex:IM-18899-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:7F19C0950A559E93|rigid:H4zcRDoN8oQ9oWUHImp8KzRTtYQ false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:O75928-2 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-348567|ensembl:ENSP00000317163|intact:EBI-7259183|intact:MINT-1455402 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:o75928-2(display_long)|uniprotkb:Msx-interacting zinc finger protein(gene name synonym)|uniprotkb:PIAS-NY protein(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT x(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT2(gene name synonym)|uniprotkb:PIAS2(gene name)|psi-mi:PIAS2(display_short)|uniprotkb:PIASX(gene name synonym)|uniprotkb:Androgen receptor-interacting protein 3(gene name synonym)|uniprotkb:DAB2-interacting protein(gene name synonym)|uniprotkb:PIASx-alpha(isoform synonym)|uniprotkb:ARIP3(isoform synonym)|uniprotkb:E3 SUMO-protein transferase PIAS2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-928002|imex:IM-18899-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) intact:EBI-348555(pias2_human)|ensembl:ENSG00000078043(gene)|ensembl:ENST00000324794(transcript)|uniprotkb:O75928-2(isoform-parent) - - isoform-comment:"Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 562." dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:JNC3UGf8YuVcrXbFnO27d4orf4I9606 intact-crc:CE721F124F44F51B|rigid:+Lt9h5C7BhUAp3zBvlQul/nmeBI false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:P51532 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:Q13363 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:Q14839 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:O75182 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:Q96ST3 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03267 uniprotkb:O75385 intact:EBI-908572|uniprotkb:Q64044|uniprotkb:Q64045|uniprotkb:Q64051 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:ikzf1_mouse(display_long)|uniprotkb:Ikzf1(gene name)|psi-mi:Ikzf1(display_short)|uniprotkb:Ikaros(gene name synonym)|uniprotkb:Lyf1(gene name synonym)|uniprotkb:Zfpn1a1(gene name synonym)|uniprotkb:Znfn1a1(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 1(gene name synonym)|uniprotkb:Lymphoid transcription factor LyF-1(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gomez-del et al. (2005) pubmed:15767674|imex:IM-18899 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-908826|imex:IM-18899-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:Q03267|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045660"(positive regulation of neutrophil differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048535"(lymph node development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048732"(gland development)|go:"GO:0060040"(retinal bipolar neuron differentiation) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903 - - - delivery method:Q03267 trasfection|comment:GFP-SUMO1 when cotransfected inhibited the interaction, possibly through sumoylation of Ikaros.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/22 2014/10/16 rogid:YfbncDLTudGGvO/RNpRf6aWFawA10090 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:D5022695821A01ED|rigid:GwlekqWrWNZG9YqpdkpcmQhVevE false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)