#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P61793	uniprotkb:Q9NZN5	intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942	psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short)	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512330|mint:MINT-1897348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N|mint:MINT-1897349(identity)	refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|mint:MINT-1897357(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/05/08	2014/10/16	rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	intact-crc:14B0DDF2893A3236|rigid:b92OKL5lzV/iX8y1QPOw4HxkYU4	false	binding-associated region:362-364(MINT-1897373)|flag tag:?-?(MINT-1897355)	myc tag:?-?(MINT-1897358)|binding-associated region:72-151(MINT-1897364)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61793	uniprotkb:Q9NZN5	intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942	psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short)	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512440|mint:MINT-1897376	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N|mint:MINT-1897377(identity)	refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|mint:MINT-1897387(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/05/08	2014/10/16	rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	intact-crc:CFD0093325F88E31|rigid:b92OKL5lzV/iX8y1QPOw4HxkYU4	false	flag tag:?-?(MINT-1897385)|binding-associated region:362-364(MINT-1897378)	binding-associated region:72-151(MINT-1897388)|myc tag:?-?(MINT-1897396)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61793	uniprotkb:O15085	intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201	intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2	psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512474|mint:MINT-1897228	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N|mint:MINT-1897229(identity)	ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N|mint:MINT-1897230(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/08	2014/10/16	rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	intact-crc:0630EAD4D15883D3|rigid:IadSLmsmOKsHf8gVsNEvUGJLZRA	false	flag tag:?-?(MINT-1897252)	binding-associated region:47-126(MINT-1897249)|maltose binding protein tag:?-?(MINT-1897243)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9JL06	uniprotkb:Q9NZN5	intact:EBI-7512524|intact:MINT-1897279	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942	psi-mi:lpar2_mouse(display_long)|uniprotkb:Lpa2(gene name synonym)|uniprotkb:Edg4(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-4(gene name synonym)|uniprotkb:Lpar2(gene name)|psi-mi:Lpar2(display_short)	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512584|mint:MINT-1897297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR004066(EDG-4 lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0009986"(cell surface)|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|mint:MINT-1897298(identity)	refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|mint:MINT-1897308(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1B|figure legend:F1A|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/08	2014/10/16	rogid:/zldgpAxmtYpNwqjywkj7UWgI0810090	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	intact-crc:71227B7B3EA9F659|rigid:T7jb81r6nVynk9cxspIu9OXX9HY	false	flag tag:?-?(MINT-1897306)|binding-associated region:346-348(MINT-1897299)	maltose binding protein tag:?-?(MINT-1897309)|binding-associated region:72-121(MINT-1897315)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9JL06	uniprotkb:O15085	intact:EBI-7512524|intact:MINT-1897279	intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2	psi-mi:lpar2_mouse(display_long)|uniprotkb:Lpa2(gene name synonym)|uniprotkb:Edg4(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-4(gene name synonym)|uniprotkb:Lpar2(gene name)|psi-mi:Lpar2(display_short)	psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512519|mint:MINT-1897260	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR004066(EDG-4 lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0009986"(cell surface)|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|mint:MINT-1897261(identity)	ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N|mint:MINT-1897269(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1B|figure legend:F1A|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/08	2014/10/16	rogid:/zldgpAxmtYpNwqjywkj7UWgI0810090	rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606	intact-crc:B346842F5016C0A6|rigid:8fd1D0vFMqwqVQiWAA49uzon9OQ	false	flag tag:?-?(MINT-1897267)|binding-associated region:346-348(MINT-1897290)	binding-associated region:47-126(MINT-1897270)|maltose binding protein tag:?-?(MINT-1897276)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61793	uniprotkb:Q9NZN5	intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201	intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942	psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short)	psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yamada et al. (2005)	pubmed:15755723|mint:MINT-5217571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7512626|mint:MINT-1897323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N|mint:MINT-1897333(identity)	refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|mint:MINT-1897324(identity)	-	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/05/08	2014/10/16	rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090	rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606	intact-crc:88802C43469C6F2F|rigid:b92OKL5lzV/iX8y1QPOw4HxkYU4	false	flag tag:?-?(MINT-1897334)	binding-associated region:72-121(MINT-1897325)|maltose binding protein tag:?-?(MINT-1897331)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)