#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q04756	uniprotkb:O43278	intact:EBI-1041722|uniprotkb:Q14726|uniprotkb:Q2M1W7|uniprotkb:Q53X47|ensembl:ENSP00000372224	intact:EBI-953990|ensembl:ENSP00000342098|uniprotkb:Q7Z7D2	psi-mi:hgfa_human(display_long)|uniprotkb:HGFAC(gene name)|psi-mi:HGFAC(display_short)	psi-mi:spit1_human(display_long)|uniprotkb:Hepatocyte growth factor activator inhibitor type 1(gene name synonym)|uniprotkb:SPINT1(gene name)|psi-mi:SPINT1(display_short)|uniprotkb:HAI1(gene name synonym)|uniprotkb:UNQ223/PRO256(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Shia et al. (2005)	pubmed:15713485	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1041746|rcsb pdb:1YC0	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001519.1|ensembl:ENSG00000109758(gene)|ensembl:ENST00000382774(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1YBW|rcsb pdb:1YC0|rcsb pdb:2R0K|rcsb pdb:2R0L|rcsb pdb:2WUB|rcsb pdb:3K2U|reactome:R-HSA-6806942|rcsb pdb:2WUC|refseq:NP_001284368.1|dip:DIP-6022N	ensembl:ENSG00000166145(gene)|ensembl:ENST00000344051(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR042482|rcsb pdb:1YC0|rcsb pdb:2MSX|rcsb pdb:4ISL|rcsb pdb:4ISN|rcsb pdb:4ISO|rcsb pdb:5EZD|rcsb pdb:5H7V|reactome:R-HSA-6806942|reactome:R-HSA-8852405|interpro:IPR011106(Seven cysteines, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR020901|interpro:IPR023415|interpro:IPR036055|interpro:IPR036880|refseq:NP_001027539.1|refseq:NP_003701.1|refseq:NP_857593.1|refseq:XP_006720720.1|dip:DIP-37949N	-	-	-	assembly:dimeric, multimeric|3d-r-factors:working 80.500%, free 78.200%|3d-resolution:2.6A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:wUngo1v72gxjGSfz7ikz7sJkLHA9606	rogid:feHnyLQq6rOSG2IW9dCGVBkcurg9606	intact-crc:9A239AF23A871FE1|rigid:+Fm9JsP+3WBmvsH73bzv3qYWlpE	false	sufficient binding region:373-655	sufficient binding region:245-303	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)