#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q10113	uniprotkb:Q1MTQ1	intact:EBI-1002268|ensemblfungi:"SPAC18G6.15.1:pep"	intact:EBI-1107767|uniprotkb:O94732|ensemblfungi:"SPBC1604.20c.1:pep"	psi-mi:mal3_schpo(display_long)|uniprotkb:mal3(gene name)|psi-mi:mal3(display_short)|uniprotkb:SPAC18G6.15(orf name)	psi-mi:tea2_schpo(display_long)|uniprotkb:tea2(gene name)|psi-mi:tea2(display_short)|uniprotkb:klp4(gene name synonym)|uniprotkb:SPBC1604.20c(orf name)|uniprotkb:Tip elongation aberrant protein 2(gene name synonym)|uniprotkb:Kinesin-like protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Browning et al. (2005)	pubmed:15665379|imex:IM-19897	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1107766|imex:IM-19897-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593678.1|ensemblfungi:SPAC18G6.15.1(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030989"(dynein-driven meiotic oscillatory nuclear movement)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0055028"(cortical microtubule)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0099609"(microtubule lateral binding)|ensemblfungi:SPAC18G6.15(gene)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|rcsb pdb:4ABO|rcsb pdb:5M97|rcsb pdb:5M9E|rcsb pdb:5MJS|dip:DIP-35342N	ensemblfungi:SPBC1604.20c(gene)|ensemblfungi:SPBC1604.20c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099117"(protein transport along microtubule to cell tip)|go:"GO:1903754"(cortical microtubule plus-end)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|refseq:NP_596620.1|reactome:R-SPO-983189|dip:DIP-35717N	-	crc64:9527D31CAA024256	crc64:0C108D4B9690A6D3	comment:"There was tight binding between mal3 and the N-terminus region of tea2 (aa 2-122) and with that including the motor region (aa 2-476), however weaker interaction was observed with the motor domain alone (aa 124-476)."|figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/06	2014/10/16	rogid:AX1qyn1e4krMTVjlDLaZE339exo284812	rogid:fpor91dosZemmxMxoelFghxk8Ik284812	intact-crc:F92B1832DFB991FD|rigid:DtBGrLz1+q06hxhAGRMnVi73WrM	false	-	necessary binding region:2-122|sufficient binding region:124-476|his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q10113	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1002268|ensemblfungi:"SPAC18G6.15.1:pep"	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:mal3_schpo(display_long)|uniprotkb:mal3(gene name)|psi-mi:mal3(display_short)|uniprotkb:SPAC18G6.15(orf name)	psi-mi:"MI:0415"(enzymatic study)	Browning et al. (2005)	pubmed:15665379|imex:IM-19897	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0192"(acetylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1108312|imex:IM-19897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_593678.1|ensemblfungi:SPAC18G6.15.1(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030989"(dynein-driven meiotic oscillatory nuclear movement)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0055028"(cortical microtubule)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0099609"(microtubule lateral binding)|ensemblfungi:SPAC18G6.15(gene)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|rcsb pdb:4ABO|rcsb pdb:5M97|rcsb pdb:5M9E|rcsb pdb:5MJS|dip:DIP-35342N	-	-	crc64:9527D31CAA024256	figure legend:Figure 3A; 3B; 4.|comment:"Mal3 stimulates the rate of ATP hydrolysis for tea2 fragments T2NM (aa 2-476) and T2NMC1 (aa 2-524) at subsaturating levels of micotubules (MTs)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/06	2014/10/16	-	rogid:AX1qyn1e4krMTVjlDLaZE339exo284812	intact-crc:CE45F099A171ED2A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q1MTQ1	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1107767|uniprotkb:O94732|ensemblfungi:"SPBC1604.20c.1:pep"	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:tea2_schpo(display_long)|uniprotkb:tea2(gene name)|psi-mi:tea2(display_short)|uniprotkb:klp4(gene name synonym)|uniprotkb:SPBC1604.20c(orf name)|uniprotkb:Tip elongation aberrant protein 2(gene name synonym)|uniprotkb:Kinesin-like protein 4(gene name synonym)	psi-mi:"MI:0415"(enzymatic study)	Browning et al. (2005)	pubmed:15665379|imex:IM-19897	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0192"(acetylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1108312|imex:IM-19897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensemblfungi:SPBC1604.20c(gene)|ensemblfungi:SPBC1604.20c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0099117"(protein transport along microtubule to cell tip)|go:"GO:1903754"(cortical microtubule plus-end)|go:"GO:1904511"(cytoplasmic microtubule plus-end)|go:"GO:1990752"(microtubule end)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|refseq:NP_596620.1|reactome:R-SPO-983189|dip:DIP-35717N	-	-	crc64:0C108D4B9690A6D3	figure legend:Figure 3A; 3B; 4.|comment:"Mal3 stimulates the rate of ATP hydrolysis for tea2 fragments T2NM (aa 2-476) and T2NMC1 (aa 2-524) at subsaturating levels of micotubules (MTs)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/06	2014/10/16	-	rogid:fpor91dosZemmxMxoelFghxk8Ik284812	intact-crc:CE45F099A171ED2A	false	-	binding-associated region:2-476	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)