#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33307 uniprotkb:Q02821 intact:EBI-5168|uniprotkb:D6VV96|ensemblfungi:YGL238W intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W psi-mi:cse1_yeast(display_long)|uniprotkb:CSE1(gene name)|psi-mi:CSE1(display_short)|uniprotkb:YGL238W(locus name)|uniprotkb:HRC135(orf name)|uniprotkb:Chromosome segregation protein CSE1(gene name synonym) psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Matsuura et al. (2004) pubmed:15602554 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041382|rcsb pdb:1WA5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011276.1|sgd:S000003207|dip:DIP-1131N|mint:P33307|ensemblfungi:YGL238W(gene)|ensemblfungi:YGL238W_mRNA(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0061015"(snRNA import into nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1WA5|rcsb pdb:1Z3H refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94 - - crc64:8D3A0CB76F2E7C00 assembly:trimeric, multimeric|3d-r-factors:working 76.5600%, free 73.2100%|3d-resolution:2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:qu/xlfTJS+QU9qYYTrvz36jplQ4559292 rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292 intact-crc:34A5D880944F907E|rigid:MVQILOc2d5GsL1P1t1BvkbfRThQ false sufficient binding region:1-960 sufficient binding region:1-530 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33307 uniprotkb:P62825 intact:EBI-5168|uniprotkb:D6VV96|ensemblfungi:YGL238W intact:EBI-286616|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|uniprotkb:Q9UDJ5 psi-mi:cse1_yeast(display_long)|uniprotkb:CSE1(gene name)|psi-mi:CSE1(display_short)|uniprotkb:YGL238W(locus name)|uniprotkb:HRC135(orf name)|uniprotkb:Chromosome segregation protein CSE1(gene name synonym) psi-mi:ran_canlf(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short) psi-mi:"MI:0114"(x-ray crystallography) Matsuura et al. (2004) pubmed:15602554 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041382|rcsb pdb:1WA5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011276.1|sgd:S000003207|dip:DIP-1131N|mint:P33307|ensemblfungi:YGL238W(gene)|ensemblfungi:YGL238W_mRNA(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0061015"(snRNA import into nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:1WA5|rcsb pdb:1Z3H rcsb pdb:5YU6|refseq:NP_001181913.1|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|rcsb pdb:1A2K|rcsb pdb:1BYU|rcsb pdb:1QG2|rcsb pdb:1QG4|rcsb pdb:1WA5|rcsb pdb:2BKU|rcsb pdb:3A6P|rcsb pdb:3RAN|rcsb pdb:5BXQ|interpro:IPR027417|rcsb pdb:3W3Z|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016442"(RISC complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1905172"(RISC complex binding) - - - assembly:trimeric, multimeric|3d-r-factors:working 76.5600%, free 73.2100%|3d-resolution:2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:qu/xlfTJS+QU9qYYTrvz36jplQ4559292 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9615 intact-crc:34A5D880944F907E|rigid:MVQILOc2d5GsL1P1t1BvkbfRThQ false sufficient binding region:1-960 sufficient binding region:2-177 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)