#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P26769 uniprotkb:P30803 intact:EBI-1027877 intact:EBI-1027903 psi-mi:adcy2_rat(display_long)|uniprotkb:Adcy2(gene name)|psi-mi:Adcy2(display_short)|uniprotkb:Adenylate cyclase type II(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 2(gene name synonym)|uniprotkb:Adenylyl cyclase 2(gene name synonym) psi-mi:adcy5_canlf(display_long)|uniprotkb:ADCY5(gene name)|psi-mi:ADCY5(display_short)|uniprotkb:Adenylate cyclase type V(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 5(gene name synonym)|uniprotkb:Adenylyl cyclase 5(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mou et al. (2005) pubmed:15591060 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041348|rcsb pdb:1TL7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0016020"(membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|rcsb pdb:1AB8|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|interpro:IPR032628|rgd:619965|refseq:NP_112269.1|reactome:R-RNO-163615|dip:DIP-164N|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-418597|reactome:R-RNO-5610787 refseq:NP_001161932.1|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR032628|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CJU|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|dip:DIP-179N - - - assembly:trimeric, multimeric|3d-r-factors:working 74.600%, free 70.200%|3d-resolution:2.8A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Zk3Wd0QamiwHrFeiB9vVGo54A4s10116 rogid:/JbcRESNO3Iro+ReDr6cy6jI3Jg9615 intact-crc:616DBC4EAEE3C929|rigid:gp++KCaEKiPRBo2kanD1AieiKhc false sufficient binding region:870-1081 sufficient binding region:445-661 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26769 uniprotkb:P04896 intact:EBI-1027877 intact:EBI-1027885|uniprotkb:Q0II85|uniprotkb:Q3SZE7|ensembl:ENSBTAP00000072381 psi-mi:adcy2_rat(display_long)|uniprotkb:Adcy2(gene name)|psi-mi:Adcy2(display_short)|uniprotkb:Adenylate cyclase type II(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 2(gene name synonym)|uniprotkb:Adenylyl cyclase 2(gene name synonym) psi-mi:gnas2_bovin(display_long)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mou et al. (2005) pubmed:15591060 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041348|rcsb pdb:1TL7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0016020"(membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|rcsb pdb:1AB8|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|interpro:IPR032628|rgd:619965|refseq:NP_112269.1|reactome:R-RNO-163615|dip:DIP-164N|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-418597|reactome:R-RNO-5610787 ensembl:ENSBTAG00000052413(gene)|ensembl:ENSBTAT00000070189(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1AZS|rcsb pdb:1AZT|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|rcsb pdb:3SN6|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6R3Q|rcsb pdb:6R4O|rcsb pdb:6R4P|rcsb pdb:7D68|rcsb pdb:7JJO|refseq:NP_851364.1|refseq:NP_001258700.1|dip:DIP-588N - - - assembly:trimeric, multimeric|3d-r-factors:working 74.600%, free 70.200%|3d-resolution:2.8A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Zk3Wd0QamiwHrFeiB9vVGo54A4s10116 rogid:rTD7fCRhOQ21mLZdPipFi9k9dEM9913 intact-crc:616DBC4EAEE3C929|rigid:gp++KCaEKiPRBo2kanD1AieiKhc false sufficient binding region:870-1081 sufficient binding region:1-394 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26769 uniprotkb:P30803 intact:EBI-1027877 intact:EBI-1027903 psi-mi:adcy2_rat(display_long)|uniprotkb:Adcy2(gene name)|psi-mi:Adcy2(display_short)|uniprotkb:Adenylate cyclase type II(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 2(gene name synonym)|uniprotkb:Adenylyl cyclase 2(gene name synonym) psi-mi:adcy5_canlf(display_long)|uniprotkb:ADCY5(gene name)|psi-mi:ADCY5(display_short)|uniprotkb:Adenylate cyclase type V(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 5(gene name synonym)|uniprotkb:Adenylyl cyclase 5(gene name synonym)|uniprotkb:"Ca(2+)-inhibitable adenylyl cyclase"(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mou et al. (2005) pubmed:15591060 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041362|rcsb pdb:1U0H - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0016020"(membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|rcsb pdb:1AB8|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|interpro:IPR032628|rgd:619965|refseq:NP_112269.1|reactome:R-RNO-163615|dip:DIP-164N|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-418597|reactome:R-RNO-5610787 refseq:NP_001161932.1|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR032628|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CJU|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|dip:DIP-179N - - - assembly:trimeric, multimeric|3d-r-factors:working 75.500%, free 72.00%|3d-resolution:2.9A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Zk3Wd0QamiwHrFeiB9vVGo54A4s10116 rogid:/JbcRESNO3Iro+ReDr6cy6jI3Jg9615 intact-crc:6BD22FB2D21AFE23|rigid:gp++KCaEKiPRBo2kanD1AieiKhc false sufficient binding region:870-1081 sufficient binding region:442-661 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26769 uniprotkb:P04896 intact:EBI-1027877 intact:EBI-1027885|uniprotkb:Q0II85|uniprotkb:Q3SZE7|ensembl:ENSBTAP00000072381 psi-mi:adcy2_rat(display_long)|uniprotkb:Adcy2(gene name)|psi-mi:Adcy2(display_short)|uniprotkb:Adenylate cyclase type II(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase 2(gene name synonym)|uniprotkb:Adenylyl cyclase 2(gene name synonym) psi-mi:gnas2_bovin(display_long)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Mou et al. (2005) pubmed:15591060 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1041362|rcsb pdb:1U0H - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0016020"(membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR009398(Adenylate cyclase-like)|interpro:IPR018297|interpro:IPR029787|interpro:IPR030672|rcsb pdb:1AB8|rcsb pdb:1AZS|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|interpro:IPR032628|rgd:619965|refseq:NP_112269.1|reactome:R-RNO-163615|dip:DIP-164N|reactome:R-RNO-170660|reactome:R-RNO-170670|reactome:R-RNO-418597|reactome:R-RNO-5610787 ensembl:ENSBTAG00000052413(gene)|ensembl:ENSBTAT00000070189(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1AZS|rcsb pdb:1AZT|rcsb pdb:1CJK|rcsb pdb:1CJT|rcsb pdb:1CJU|rcsb pdb:1CJV|rcsb pdb:1CS4|rcsb pdb:1CUL|rcsb pdb:1TL7|rcsb pdb:1U0H|rcsb pdb:2GVD|rcsb pdb:2GVZ|rcsb pdb:3C14|rcsb pdb:3C15|rcsb pdb:3C16|rcsb pdb:3G82|rcsb pdb:3MAA|rcsb pdb:3SN6|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6R3Q|rcsb pdb:6R4O|rcsb pdb:6R4P|rcsb pdb:7D68|rcsb pdb:7JJO|refseq:NP_851364.1|refseq:NP_001258700.1|dip:DIP-588N - - - assembly:trimeric, multimeric|3d-r-factors:working 75.500%, free 72.00%|3d-resolution:2.9A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Zk3Wd0QamiwHrFeiB9vVGo54A4s10116 rogid:rTD7fCRhOQ21mLZdPipFi9k9dEM9913 intact-crc:6BD22FB2D21AFE23|rigid:gp++KCaEKiPRBo2kanD1AieiKhc false sufficient binding region:870-1081 sufficient binding region:1-394 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)