#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q80T11 uniprotkb:Q9ES64-3 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-7418919|intact:MINT-2491350 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:q9es64-3(display_long)|uniprotkb:a1(isoform synonym)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7418929|mint:MINT-1896737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1896738(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1896739(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F2A|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:6DjzPH4e5qP++FVD57IMB18nfZc10090 intact-crc:DD68111EAAAD2746|rigid:Sq7k9PV54/Oda44A9NEBaMzgL64 false - glutathione s tranferase tag:?-?(MINT-1896741)|binding-associated region:87-171(MINT-1896747) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64-3 uniprotkb:Q80T11 intact:EBI-7418919|intact:MINT-2491350 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 psi-mi:q9es64-3(display_long)|uniprotkb:a1(isoform synonym)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym) psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7418948|mint:MINT-1896759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7418968(isoform-parent)|mint:MINT-1896765(identity) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1896760(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F2A|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:6DjzPH4e5qP++FVD57IMB18nfZc10090 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 intact-crc:F5066FA78CD96D61|rigid:Sq7k9PV54/Oda44A9NEBaMzgL64 false glutathione s tranferase tag:?-?(MINT-1896773) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64 uniprotkb:Q99PJ1 intact:EBI-7418968|uniprotkb:Q9CVG7|uniprotkb:Q9ES65|intact:MINT-1895746|uniprotkb:Q91XD1 intact:EBI-6556746|uniprotkb:D6RCH0|uniprotkb:E9Q7D7|uniprotkb:E9Q7R2|uniprotkb:F6KJX4|uniprotkb:F6KKG6|uniprotkb:F6R5Z7|uniprotkb:F6RBV2|uniprotkb:F6U3Q6|uniprotkb:F6UPC9|uniprotkb:F6VPR3|uniprotkb:F6WUN7|uniprotkb:F6X715|uniprotkb:F6XPA1|uniprotkb:F6Y0A5|uniprotkb:F6YP25|uniprotkb:F6YZQ9|uniprotkb:F7ASH0|uniprotkb:F7CIN1|uniprotkb:F7D5J8|uniprotkb:F7DFU0|uniprotkb:F8VQ61|uniprotkb:H3BKS0|uniprotkb:Q0ZM15|uniprotkb:Q0ZM16|uniprotkb:Q0ZM18|uniprotkb:Q0ZM19|uniprotkb:Q0ZM20|uniprotkb:Q0ZM21|uniprotkb:Q0ZM22|uniprotkb:Q0ZM23|uniprotkb:Q0ZM24|uniprotkb:Q0ZM25|uniprotkb:Q0ZM26|uniprotkb:Q0ZM27|uniprotkb:Q0ZM28|uniprotkb:Q0ZM29|uniprotkb:Q0ZM30|uniprotkb:Q0ZM31|uniprotkb:Q0ZM32|uniprotkb:Q0ZM33|uniprotkb:Q0ZM34|uniprotkb:Q0ZM35|uniprotkb:Q0ZM37|uniprotkb:Q2VQG7|uniprotkb:Q3URZ1|uniprotkb:Q3UTS7|ensembl:ENSMUSP00000141792|uniprotkb:E9Q7R1 psi-mi:ush1c_mouse(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:PDZ domain-containing protein(gene name synonym) psi-mi:pcd15_mouse(display_long)|uniprotkb:Pcdh15(gene name)|psi-mi:Pcdh15(display_short) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7418962|mint:MINT-1896777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030237|mint:Q9ES64|refseq:NP_001157205.1|refseq:NP_710143.2|refseq:NP_076138.2|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030507"(spectrin binding)|go:"GO:0032029"(myosin tail binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0034622"|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1904106"(protein localization to microvillus)|go:"GO:1904970"(brush border assembly)|go:"GO:1990435"(upper tip-link density)|rcsb pdb:1V6B|interpro:IPR036034|mint:MINT-1896778(identity) ensembl:ENSMUSG00000052613(gene)|ensembl:ENSMUST00000193361(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001964"(startle response)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048839"(inner ear development)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060013"(righting reflex)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030718|interpro:IPR041149|mint:Q99PJ1|rcsb pdb:4APX|rcsb pdb:4AQ8|rcsb pdb:4AQA|rcsb pdb:4AQE|rcsb pdb:4AXW|rcsb pdb:4XXW|rcsb pdb:5KJ4|rcsb pdb:5W1D|rcsb pdb:6BWN|rcsb pdb:6C10|rcsb pdb:6C13|rcsb pdb:6C14|rcsb pdb:6CV7|rcsb pdb:6EET|rcsb pdb:6N22|rcsb pdb:5TPK|refseq:XP_006513219.1|refseq:NP_075604.2|refseq:NP_001136207.1|refseq:NP_001136208.1|refseq:NP_001136209.1|refseq:NP_001136210.1|refseq:NP_001136211.1|refseq:NP_001136212.1|refseq:NP_001136213.1|refseq:NP_001136214.1|refseq:NP_001136215.1|refseq:NP_001136218.1|refseq:NP_001136219.1|refseq:NP_001136220.1|refseq:NP_001136232.1|dip:DIP-42151N|mint:MINT-1896788(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|figure legend:F2C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:FPcvzbPYBwFxmWloqxEfmQmaMV410090 rogid:Hg/g9gB38Qx+yyHMlcicxTlTvmA10090 intact-crc:FEFF806D4C24B78B|rigid:0IjHNwPaM9Wnf3UQ9NMkJSO/dsA false binding-associated region:211-295(MINT-1896798)|glutathione s tranferase tag:?-?(MINT-1896786) binding-associated region:?-?(MINT-1896796) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64-1 uniprotkb:Q9ES64-2 intact:EBI-7419082|intact:MINT-1895764 intact:EBI-7419098|intact:MINT-2568753 psi-mi:q9es64-1(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:b3(isoform synonym) psi-mi:q9es64-2(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:b2(isoform synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419092|mint:MINT-1896896 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7418968(ush1c_mouse)|mint:MINT-1896907(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1896897(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2D|figure legend:F2E|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:FPcvzbPYBwFxmWloqxEfmQmaMV410090 rogid:1QuhHkf04IpombtmMRk9J1ASavY10090 intact-crc:22EBADC14B78AACB|rigid:kJfnI/NtGeI1Knb8KZHhPA0HKsc false binding-associated region:87-295(MINT-1896908) glutathione s tranferase tag:?-?(MINT-1896905)|binding-associated region:417-482(MINT-1896898) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99PF4 uniprotkb:Q9ES64-3 intact:EBI-7419021|uniprotkb:Q9D4N9|uniprotkb:Q99NH1|intact:MINT-1895823|uniprotkb:E9QP63|ensembl:ENSMUSP00000101101|uniprotkb:Q5QGS3|uniprotkb:Q5QGS4|uniprotkb:Q5QGS7|uniprotkb:Q5QGS8 intact:EBI-7418919|intact:MINT-2491350 psi-mi:cad23_mouse(display_long)|uniprotkb:Cdh23(gene name)|psi-mi:Cdh23(display_short)|uniprotkb:Otocadherin(gene name synonym) psi-mi:q9es64-3(display_long)|uniprotkb:a1(isoform synonym)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419069|mint:MINT-1896841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075859.2|ensembl:ENSMUSG00000012819(gene)|ensembl:ENSMUST00000105461(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0006816"(calcium ion transport)|go:"GO:0098683"(cochlear hair cell ribbon synapse)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|go:"GO:0060091"(kinocilium)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR033030|mint:Q99PF4|rcsb pdb:2WBX|rcsb pdb:2WCP|rcsb pdb:2WD0|rcsb pdb:2WHV|rcsb pdb:3MVS|rcsb pdb:4AQ8|rcsb pdb:4AQA|rcsb pdb:4AQE|rcsb pdb:4AXW|rcsb pdb:4XXW|rcsb pdb:5I8D|rcsb pdb:5TFK|rcsb pdb:5TFL|rcsb pdb:5ULU|rcsb pdb:5UN2|rcsb pdb:5UZ8|rcsb pdb:5VH2|rcsb pdb:5VT8|rcsb pdb:5WJM|rcsb pdb:6N2E|rcsb pdb:4APX|dip:DIP-42152N|refseq:XP_006513665.1|refseq:XP_017169418.1|mint:MINT-1896842(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1896847(identity) - comment:mint|function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. Cadherin 23 may function as hair bundle organizer perhaps by cross-linking the stereocilia|function:"Defects in Cdh23 are the cause of waltzer (v) phenotype. Waltzer mice are characterized by deafness and vestibular dysfunction due to degeneration of the neuroepithelium within the inner ear"|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:7unoOfYXoR0Paq0PlxYSWt8ppoU10090 rogid:6DjzPH4e5qP++FVD57IMB18nfZc10090 intact-crc:0638D7FA1CC45A0A|rigid:xq+3jJ2H942mda5LenNOHaQLMwY false - glutathione s tranferase tag:?-?(MINT-1896848) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64-2 uniprotkb:Q9ES64-2 intact:EBI-7419098|intact:MINT-2568753 intact:EBI-7419098|intact:MINT-2568753 psi-mi:q9es64-2(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:b2(isoform synonym) psi-mi:q9es64-2(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:b2(isoform synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419127|mint:MINT-1896926 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7418968(isoform-parent)|mint:MINT-1896927(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1896938(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2D|figure legend:F2E|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:1QuhHkf04IpombtmMRk9J1ASavY10090 rogid:1QuhHkf04IpombtmMRk9J1ASavY10090 intact-crc:AA16200F0D4F442D|rigid:fICpI8ZtVoBx9gQAeoqQ8DY0Cps false binding-associated region:87-295(MINT-1896928) binding-associated region:417-482(MINT-1896939)|glutathione s tranferase tag:?-?(MINT-1896945) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:Q80T11 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419177|mint:MINT-1896974 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1896975(identity) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1896980(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" figure legend:F3C|figure legend:F3E|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 intact-crc:0A0F90B03BAF5508|rigid:Wp43s/IC4BgHnK85wFKVboqXQgk false - glutathione s tranferase tag:?-?(MINT-1896988)|binding-associated region:128-385(MINT-1896981) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:P97479 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419196|mint:MINT-1896995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1896996(identity) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794|mint:MINT-1897005(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:67DD2356590B15DA|rigid:ZmCRyzHWQXwp72489RH/BwVNXC0 false glutathione s tranferase tag:?-?(MINT-1897003) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64-3 uniprotkb:Q9ES64-2 intact:EBI-7418919|intact:MINT-2491350 intact:EBI-7419098|intact:MINT-2568753 psi-mi:q9es64-3(display_long)|uniprotkb:a1(isoform synonym)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym) psi-mi:q9es64-2(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:b2(isoform synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419152|mint:MINT-1896952 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7418968(isoform-parent)|mint:MINT-1896953(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1896961(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2D|figure legend:F2E|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:6DjzPH4e5qP++FVD57IMB18nfZc10090 rogid:1QuhHkf04IpombtmMRk9J1ASavY10090 intact-crc:4715F9E51D8D4DE3|rigid:FBBv+xME9lrdycxnTx27AIyvg58 false binding-associated region:87-295(MINT-1896954) glutathione s tranferase tag:?-?(MINT-1896962)|binding-associated region:417-482(MINT-1896968) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:P97479 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419228|mint:MINT-1897066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1897073(identity) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794|mint:MINT-1897067(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|figure legend:F4F|figure legend:F4D|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:186FD2318E477491|rigid:ZmCRyzHWQXwp72489RH/BwVNXC0 false glutathione s tranferase tag:?-?(MINT-1897083)|binding-associated region:128-385(MINT-1897085) binding-associated region:?-?(IPR009065) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:P97479 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419277|mint:MINT-1897099 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1897109(identity) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794|mint:MINT-1897100(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|figure legend:F4F|figure legend:F4D|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:F69795E5A3F5F79D|rigid:ZmCRyzHWQXwp72489RH/BwVNXC0 false glutathione s tranferase tag:?-?(MINT-1897116)|binding-associated region:128-385(MINT-1897110) binding-associated region:1747-2205(IPR009065) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:Q9ES64-3 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-7418919|intact:MINT-2491350 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:q9es64-3(display_long)|uniprotkb:a1(isoform synonym)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:PDZ domain-containing protein(gene name synonym)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419210|mint:MINT-1897011 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1897012(identity) intact:EBI-7418968(isoform-parent)|mint:MINT-1897017(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3B|figure legend:F3C|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:6DjzPH4e5qP++FVD57IMB18nfZc10090 intact-crc:074F805335ED22F5|rigid:Sq7k9PV54/Oda44A9NEBaMzgL64 false glutathione s tranferase tag:?-?(MINT-1897027)|binding-associated region:385-453(MINT-1897029) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES64 uniprotkb:Q99PJ1 intact:EBI-7418968|uniprotkb:Q9CVG7|uniprotkb:Q9ES65|intact:MINT-1895746|uniprotkb:Q91XD1 intact:EBI-6556746|uniprotkb:D6RCH0|uniprotkb:E9Q7D7|uniprotkb:E9Q7R2|uniprotkb:F6KJX4|uniprotkb:F6KKG6|uniprotkb:F6R5Z7|uniprotkb:F6RBV2|uniprotkb:F6U3Q6|uniprotkb:F6UPC9|uniprotkb:F6VPR3|uniprotkb:F6WUN7|uniprotkb:F6X715|uniprotkb:F6XPA1|uniprotkb:F6Y0A5|uniprotkb:F6YP25|uniprotkb:F6YZQ9|uniprotkb:F7ASH0|uniprotkb:F7CIN1|uniprotkb:F7D5J8|uniprotkb:F7DFU0|uniprotkb:F8VQ61|uniprotkb:H3BKS0|uniprotkb:Q0ZM15|uniprotkb:Q0ZM16|uniprotkb:Q0ZM18|uniprotkb:Q0ZM19|uniprotkb:Q0ZM20|uniprotkb:Q0ZM21|uniprotkb:Q0ZM22|uniprotkb:Q0ZM23|uniprotkb:Q0ZM24|uniprotkb:Q0ZM25|uniprotkb:Q0ZM26|uniprotkb:Q0ZM27|uniprotkb:Q0ZM28|uniprotkb:Q0ZM29|uniprotkb:Q0ZM30|uniprotkb:Q0ZM31|uniprotkb:Q0ZM32|uniprotkb:Q0ZM33|uniprotkb:Q0ZM34|uniprotkb:Q0ZM35|uniprotkb:Q0ZM37|uniprotkb:Q2VQG7|uniprotkb:Q3URZ1|uniprotkb:Q3UTS7|ensembl:ENSMUSP00000141792|uniprotkb:E9Q7R1 psi-mi:ush1c_mouse(display_long)|uniprotkb:Ush1c(gene name)|psi-mi:Ush1c(display_short)|uniprotkb:Usher syndrome type-1C protein homolog(gene name synonym)|uniprotkb:PDZ domain-containing protein(gene name synonym) psi-mi:pcd15_mouse(display_long)|uniprotkb:Pcdh15(gene name)|psi-mi:Pcdh15(display_short) psi-mi:"MI:0018"(two hybrid) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7419311|mint:MINT-1896869 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030237|mint:Q9ES64|refseq:NP_001157205.1|refseq:NP_710143.2|refseq:NP_076138.2|interpro:IPR001478(PDZ/DHR/GLGF)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030507"(spectrin binding)|go:"GO:0032029"(myosin tail binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0034622"|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1904106"(protein localization to microvillus)|go:"GO:1904970"(brush border assembly)|go:"GO:1990435"(upper tip-link density)|rcsb pdb:1V6B|interpro:IPR036034|mint:MINT-1896870(identity) ensembl:ENSMUSG00000052613(gene)|ensembl:ENSMUST00000193361(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001964"(startle response)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048839"(inner ear development)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0050973"(detection of mechanical stimulus involved in equilibrioception)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060013"(righting reflex)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030718|interpro:IPR041149|mint:Q99PJ1|rcsb pdb:4APX|rcsb pdb:4AQ8|rcsb pdb:4AQA|rcsb pdb:4AQE|rcsb pdb:4AXW|rcsb pdb:4XXW|rcsb pdb:5KJ4|rcsb pdb:5W1D|rcsb pdb:6BWN|rcsb pdb:6C10|rcsb pdb:6C13|rcsb pdb:6C14|rcsb pdb:6CV7|rcsb pdb:6EET|rcsb pdb:6N22|rcsb pdb:5TPK|refseq:XP_006513219.1|refseq:NP_075604.2|refseq:NP_001136207.1|refseq:NP_001136208.1|refseq:NP_001136209.1|refseq:NP_001136210.1|refseq:NP_001136211.1|refseq:NP_001136212.1|refseq:NP_001136213.1|refseq:NP_001136214.1|refseq:NP_001136215.1|refseq:NP_001136218.1|refseq:NP_001136219.1|refseq:NP_001136220.1|refseq:NP_001136232.1|dip:DIP-42151N|mint:MINT-1896880(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/05/08 2014/10/16 rogid:FPcvzbPYBwFxmWloqxEfmQmaMV410090 rogid:Hg/g9gB38Qx+yyHMlcicxTlTvmA10090 intact-crc:D130AD28627368F6|rigid:0IjHNwPaM9Wnf3UQ9NMkJSO/dsA false tag:?-?(MINT-1896878)|binding-associated region:87-295(MINT-1896871) binding-associated region:?-?(MINT-1896881)|tag:?-?(MINT-1896889) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80T11 uniprotkb:P97479 intact:EBI-7418889|intact:MINT-1896722|uniprotkb:Q80UG0|ensembl:ENSMUSP00000099326 intact:EBI-1149557|uniprotkb:E9QLP7|uniprotkb:Q5MJ57|ensembl:ENSMUSP00000102745 psi-mi:ush1g_mouse(display_long)|uniprotkb:Ush1g(gene name)|psi-mi:Ush1g(display_short)|uniprotkb:Sans(gene name synonym)|uniprotkb:Scaffold protein containing ankyrin repeats and SAM domain(gene name synonym)|uniprotkb:Jackson shaker protein(gene name synonym) psi-mi:myo7a_mouse(display_long)|uniprotkb:Myo7a(gene name)|psi-mi:Myo7a(display_short)|uniprotkb:Myo7(gene name synonym) psi-mi:"MI:0428"(imaging technique) Adato et al. (2005) pubmed:15590703|mint:MINT-5217402 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7419371|mint:MINT-1897039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789817.1|ensembl:ENSMUSG00000045288(gene)|ensembl:ENSMUST00000103037(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030507"(spectrin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037602|mint:MINT-1897047(identity) refseq:XP_011239993.1|refseq:NP_001243010.1|refseq:NP_001243012.1|refseq:NP_032689.2|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007600"(sensory perception)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030507"(spectrin binding)|go:"GO:0031477"(myosin VII complex)|go:"GO:0031982"(vesicle)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042470"(melanosome)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042490"(mechanoreceptor differentiation)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048563"(post-embryonic animal organ morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0050957"(equilibrioception)|go:"GO:0051015"(actin filament binding)|go:"GO:0051875"(pigment granule localization)|go:"GO:0051904"(pigment granule transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0120044"(stereocilium base)|go:"GO:1990435"(upper tip-link density)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019749|interpro:IPR027417|interpro:IPR029071|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106|interpro:IPR036961|interpro:IPR038185|interpro:IPR041793|ensembl:ENSMUSG00000030761(gene)|ensembl:ENSMUST00000107128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001750"(photoreceptor outer segment)|rcsb pdb:3PVL|rcsb pdb:5WST|rcsb pdb:5WSU|rcsb pdb:5WSV|reactome:R-MMU-2453902|interpro:IPR041794|mint:MINT-1897040(identity) - comment:mint|function:Unknown. Required for normal hearing. May have a role in the development and maintenance of the stereocilia bundles. Might function as an anchoring/scaffolding protein in hair cells. Could be involved in the functional network formed by USH1C, CDH23 and MYO7A that is required for cohesion of the growing hair bundle|function:"Defects in Ush1g are the cause of the Jackson shaker phenotypes (js). Jackson shaker mice carry recessive mutations predicted to inactivate Ush1g by frameshift resulting in a truncated protein lacking the C-terminal SAM domain. The js phenotype is characterized by deafness, abnormal behavior (circling and/or head-tossing) and degeneration of inner ear neuroepithelia. Defects in the formation of protein complex including Ush1g may disrupt stereocilia bundle in js mice"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4C|comment:homomint|comment:mint taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/05/08 2014/10/16 rogid:/CmiUJ+sZBsg2VrRE0DJWi6EFt410090 rogid:CWTUqQmbi4vwfU1RfwyO7qdpmjQ10090 intact-crc:EA9D2B410219D3CB|rigid:ZmCRyzHWQXwp72489RH/BwVNXC0 false - - 1 1 psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)