#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:E3PRJ4 uniprotkb:E3PRJ5 intact:EBI-1040628|uniprotkb:Q9ZFE5|intact:EBI-9012047|ensemblbacteria:CBH21498 intact:EBI-1040624|uniprotkb:Q9ZFE6|intact:EBI-9012049|ensemblbacteria:CBH21499 psi-mi:kame_acesd(display_long)|uniprotkb:D-lysine 5,6-aminomutase beta subunit(gene name synonym)|uniprotkb:L-beta-lysine 5,6-aminomutase beta subunit(gene name synonym)|uniprotkb:CLOST_1378(locus name)|uniprotkb:kamE(gene name)|psi-mi:kamE(display_short) psi-mi:kamd_acesd(display_long)|uniprotkb:D-lysine 5,6-aminomutase alpha subunit(gene name synonym)|uniprotkb:L-beta-lysine 5,6-aminomutase alpha subunit(gene name synonym)|uniprotkb:CLOST_1379(locus name)|uniprotkb:kamD(gene name)|psi-mi:kamD(display_short) psi-mi:"MI:0114"(x-ray crystallography) Berkovitch et al. (2004) pubmed:15514022 taxid:499177(closd)|taxid:499177(Clostridium sticklandii DSM 519) taxid:499177(closd)|taxid:499177(Clostridium sticklandii DSM 519) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1040653|rcsb pdb:1XRS - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006158("Cobalamin (vitamin B12)-binding")|rcsb pdb:1XRS|ensemblbacteria:CBH21498(transcript)|ensemblbacteria:CLOST_1378(gene)|go:"GO:0031419"(cobalamin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047702"(beta-lysine 5,6-aminomutase activity)|go:"GO:0047826"(D-lysine 5,6-aminomutase activity)|interpro:IPR028991|interpro:IPR036724|interpro:IPR036843 interpro:IPR016176("Cobalamin (vitamin B12)-dependent enzyme, catalytic")|interpro:IPR015130(D-Lysine 5,6-aminomutase alpha subunit)|rcsb pdb:1XRS|ensemblbacteria:CBH21499(transcript)|ensemblbacteria:CLOST_1379(gene)|go:"GO:0031419"(cobalamin binding)|go:"GO:0047702"(beta-lysine 5,6-aminomutase activity)|go:"GO:0047826"(D-lysine 5,6-aminomutase activity)|interpro:IPR037086 - - - assembly:tetrameric, multimeric|3d-r-factors:working 80.100%, free 73.800%|3d-resolution:2.8A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Pso4UTxsC0NdxsfwDqRn0lTxLCg499177 rogid:9jV2pU+k73/bZkB5FSO+qSF4eUI499177 intact-crc:35D4214A6767AC93|rigid:ptCj3K36ZYDJk3epKfC9v74NTvY false sufficient binding region:1-262 sufficient binding region:1-516 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14836 uniprotkb:Q9D777 intact:EBI-519160|uniprotkb:Q7Z6F5|ensembl:ENSP00000261652|uniprotkb:B2R8B0|uniprotkb:Q32LX4|uniprotkb:B7Z6V8 intact:EBI-1040634|uniprotkb:Q9ERP1 psi-mi:tr13b_human(display_long)|uniprotkb:Transmembrane activator and CAML interactor(gene name synonym)|uniprotkb:TNFRSF13B(gene name)|psi-mi:TNFRSF13B(display_short)|uniprotkb:TACI(gene name synonym) psi-mi:tnf13_mouse(display_long)|uniprotkb:Tnfsf13(gene name)|psi-mi:Tnfsf13(display_short)|uniprotkb:April(gene name synonym)|uniprotkb:A proliferation-inducing ligand(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Berkovitch et al. (2004) pubmed:15514022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1040664|rcsb pdb:1XU1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000240505(gene)|ensembl:ENST00000261652(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR015384(TACI, cysteine-rich domain)|interpro:IPR022317|rcsb pdb:1XU1|rcsb pdb:1XUT|reactome:R-HSA-5669034|refseq:NP_036584.1|dip:DIP-6224N refseq:NP_001152977.1|refseq:NP_076006.2|interpro:IPR021184|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1U5X|rcsb pdb:1U5Y|rcsb pdb:1U5Z|rcsb pdb:1XU1|rcsb pdb:1XU2|rcsb pdb:3K48|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0050776"(regulation of immune response)|reactome:R-MMU-450520|reactome:R-MMU-5669034 - - - assembly:hexameric, multimeric|3d-r-factors:working 83.300%, free 79.700%|3d-resolution:1.9A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:Fb5PWKczyf8I9x5c9eE36y4hQjM9606 rogid:+r/XLJ7cqIOiXhKlo9KCq7RrW9810090 intact-crc:FA403FDBC1A8880A|rigid:jFoznchxiNMsHlG1D6Sl2EAo40A false sufficient binding region:68-109 sufficient binding region:104-241 3 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9D777 uniprotkb:Q02223 intact:EBI-1040634|uniprotkb:Q9ERP1 intact:EBI-519945|ensembl:ENSP00000053243|uniprotkb:Q2TQ40 psi-mi:tnf13_mouse(display_long)|uniprotkb:Tnfsf13(gene name)|psi-mi:Tnfsf13(display_short)|uniprotkb:April(gene name synonym)|uniprotkb:A proliferation-inducing ligand(gene name synonym) psi-mi:tnr17_human(display_long)|uniprotkb:B-cell maturation protein(gene name synonym)|uniprotkb:TNFRSF17(gene name)|psi-mi:TNFRSF17(display_short)|uniprotkb:BCM(gene name synonym)|uniprotkb:BCMA(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Berkovitch et al. (2004) pubmed:15514022 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1040675|rcsb pdb:1XU2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001152977.1|refseq:NP_076006.2|interpro:IPR021184|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|rcsb pdb:1U5X|rcsb pdb:1U5Y|rcsb pdb:1U5Z|rcsb pdb:1XU1|rcsb pdb:1XU2|rcsb pdb:3K48|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0050776"(regulation of immune response)|reactome:R-MMU-450520|reactome:R-MMU-5669034 refseq:NP_001183.2|ensembl:ENSG00000048462(gene)|ensembl:ENST00000053243(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR015337(BCMA, TALL-1 binding)|interpro:IPR022320|interpro:IPR043521|rcsb pdb:1OQD|rcsb pdb:1XU2|rcsb pdb:2KN1|rcsb pdb:4ZFO|rcsb pdb:6J7W|reactome:R-HSA-5669034 - - - assembly:hexameric, multimeric|3d-r-factors:working 82.200%, free 78.700%|3d-resolution:2.35A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:+r/XLJ7cqIOiXhKlo9KCq7RrW9810090 rogid:tiKhIJYqKe+Ep+8oNGn3YwAxCEg9606 intact-crc:45A8C28025BAE460|rigid:JhAsoQTxhYMPtXZJ4TvWqyEOT2A false sufficient binding region:104-241 sufficient binding region:5-51 3 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)