#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0018"(two hybrid) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1004454|imex:IM-19520-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:55530FA795759994|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false mutation decreasing interaction:275-275|necessary binding region:193-249|mutation increasing interaction:267-267|tag:n-n tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1004627|imex:IM-19520-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - figure legend:Fig. 3D, 3E, 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo) - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:B767A985201F547C|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false mutation decreasing interaction:275-275|necessary binding region:193-249 - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1004641|imex:IM-19520-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - stimulant:This interaction is stimulated by excess GDP.|inhibition:This interaction is inhibited by GTP-gamma-S.|figure legend:Fig. 4A, 5A, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo) - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:728C6769A3F63C22|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false necessary binding region:193-249|mutation decreasing interaction:275-275 - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0419"(gtpase assay) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1004711|imex:IM-19520-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - figure legend:4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:14A78BCE0EEA98EE|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false his tag:n-n sufficient binding region:28-354|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0401"(biochemical) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1004789|imex:IM-19520-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - inhibition:This interaction is inhibited by a peptide corresponding to amino acids 423-461 or gpr-1/gpr-2.|figure legend:4B, 4C, 4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:115B4D7A05F11AF4|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false his tag:n-n|necessary binding region:193-249 sufficient binding region:28-354|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9GSX9-1 uniprotkb:P51875 intact:EBI-1004494|ensemblmetazoa:Y69A2AR.2a.1 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 psi-mi:q9gsx9-1(display_long)|uniprotkb:ric-8(gene name)|psi-mi:ric-8(display_short)|uniprotkb:Resistance to inhibitors of cholinesterase protein 8(gene name synonym)|uniprotkb:Y69A2AR.2(orf name) psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Afshar et al. (2004) pubmed:15479639|imex:IM-19520 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1004816|imex:IM-19520-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331575(q9gsx9_caeel)|ensemblmetazoa:WBGene00004367(gene)|ensemblmetazoa:Y69A2AR.2a.1(transcript) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - stimulant:This interaction is stimulated by GDP.|figure legend:S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/01 2014/10/16 rogid:FBq1YkO6kb2sfetEdHv0o9PFBRI6239 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 intact-crc:22E1C857528B9B4C|rigid:wwmin5BkjwmQ2LPbz6w+Ff62I9U false his tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)