#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P15436 uniprotkb:P46957 intact:EBI-6134|uniprotkb:D6VRP8|ensemblfungi:YDL102W intact:EBI-6080|uniprotkb:D6VWI1|ensemblfungi:YJR006W psi-mi:dpod_yeast(display_long)|uniprotkb:POL3(gene name)|psi-mi:POL3(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:TEX1(gene name synonym)|uniprotkb:YDL102W(locus name)|uniprotkb:D2366(orf name)|uniprotkb:DNA polymerase III(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym) psi-mi:dpod2_yeast(display_long)|uniprotkb:POL31(gene name)|psi-mi:POL31(display_short)|uniprotkb:HUS2(gene name synonym)|uniprotkb:SDP5(gene name synonym)|uniprotkb:YJR006W(locus name)|uniprotkb:J1427(orf name)|uniprotkb:YJR83.7(orf name)|uniprotkb:Hydroxyurea-sensitive protein 2(gene name synonym)|uniprotkb:HYS2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sanchez et al. (2004) pubmed:15173383|imex:IM-19112 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-865157|imex:IM-19112-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010181.2|sgd:S000002260|dip:DIP-2524N|mint:P15436|ensemblfungi:YDL102W(gene)|ensemblfungi:YDL102W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3IAY|rcsb pdb:6P1H|rcsb pdb:7KC0|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_012539.1|sgd:S000003766|dip:DIP-2525N|mint:P46957|ensemblfungi:YJR006W(gene)|ensemblfungi:YJR006W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD|reactome:R-SCE-69166|reactome:R-SCE-69183 - crc64:16E4245C5DCC66DB crc64:F9E200BFE97A2C07 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/22 2014/10/16 rogid:B6UmbmYRvxvUeMx9GmQ/nLy81+M559292 rogid:/snR2U+Lgzyzq1V9PZG01x39304559292 intact-crc:7C98465E7C94934C|rigid:1IfbAiARXWCzX+FhF57qY3rU/XU false sufficient binding region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P15436 uniprotkb:P46957 intact:EBI-6134|uniprotkb:D6VRP8|ensemblfungi:YDL102W intact:EBI-6080|uniprotkb:D6VWI1|ensemblfungi:YJR006W psi-mi:dpod_yeast(display_long)|uniprotkb:POL3(gene name)|psi-mi:POL3(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:TEX1(gene name synonym)|uniprotkb:YDL102W(locus name)|uniprotkb:D2366(orf name)|uniprotkb:DNA polymerase III(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym) psi-mi:dpod2_yeast(display_long)|uniprotkb:POL31(gene name)|psi-mi:POL31(display_short)|uniprotkb:HUS2(gene name synonym)|uniprotkb:SDP5(gene name synonym)|uniprotkb:YJR006W(locus name)|uniprotkb:J1427(orf name)|uniprotkb:YJR83.7(orf name)|uniprotkb:Hydroxyurea-sensitive protein 2(gene name synonym)|uniprotkb:HYS2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Sanchez et al. (2004) pubmed:15173383|imex:IM-19112 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-865175|imex:IM-19112-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010181.2|sgd:S000002260|dip:DIP-2524N|mint:P15436|ensemblfungi:YDL102W(gene)|ensemblfungi:YDL102W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005657"(replication fork)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:3IAY|rcsb pdb:6P1H|rcsb pdb:7KC0|reactome:R-SCE-69166|reactome:R-SCE-69183 refseq:NP_012539.1|sgd:S000003766|dip:DIP-2525N|mint:P46957|ensemblfungi:YJR006W(gene)|ensemblfungi:YJR006W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|rcsb pdb:6P1H|rcsb pdb:6V8P|rcsb pdb:6V93|rcsb pdb:7LXD|reactome:R-SCE-69166|reactome:R-SCE-69183 - crc64:16E4245C5DCC66DB crc64:F9E200BFE97A2C07 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/22 2014/10/16 rogid:B6UmbmYRvxvUeMx9GmQ/nLy81+M559292 rogid:/snR2U+Lgzyzq1V9PZG01x39304559292 intact-crc:23CE2C1FFEA5AC8B|rigid:1IfbAiARXWCzX+FhF57qY3rU/XU false necessary binding region:?-?|mutation decreasing interaction:1056-1056|mutation decreasing interaction:1059-1059|mutation decreasing interaction:1069-1069|mutation decreasing interaction:1074-1074|mutation decreasing interaction:1047-1047|mutation decreasing interaction:1057-1057|mutation decreasing interaction:1058-1058|mutation decreasing interaction:1064-1064 mutation increasing interaction:358-358 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30316 uniprotkb:P87324 intact:EBI-865207|uniprotkb:Q10016|uniprotkb:Q9USU0|uniprotkb:Q9UU61|ensemblfungi:"SPBC336.04.1:pep" intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep" psi-mi:dpod_schpo(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase III(gene name synonym)|uniprotkb:pol3(gene name)|psi-mi:pol3(display_short)|uniprotkb:pold(gene name synonym)|uniprotkb:SPBC336.04(orf name) psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name) psi-mi:"MI:0018"(two hybrid) Sanchez et al. (2004) pubmed:15173383|imex:IM-19112 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-865242|imex:IM-19112-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596124.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR025687|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|ensemblfungi:SPBC336.04(gene)|ensemblfungi:SPBC336.04.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606 interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606 - - - comment:"Interaction only occurs in presence of cdc27 (P30261). This is not a bridge molecule but may act to stabilise cdc1 (P87324)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/02/22 2014/10/16 rogid:+fzXa8W77qXirKXf5Ydzy7GE7ts284812 rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812 intact-crc:1C61614E03F1CE1E|rigid:Hz1LUVb87NGONmuJDSJc3gux8cc false mutation decreasing interaction:1040-1040|mutation decreasing interaction:1043-1043|mutation decreasing interaction:1053-1053|mutation decreasing interaction:1058-1058|mutation decreasing interaction:1058-1058 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30316 uniprotkb:P87324 intact:EBI-865207|uniprotkb:Q10016|uniprotkb:Q9USU0|uniprotkb:Q9UU61|ensemblfungi:"SPBC336.04.1:pep" intact:EBI-865227|ensemblfungi:"SPAC27E2.05.1:pep" psi-mi:dpod_schpo(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase III(gene name synonym)|uniprotkb:pol3(gene name)|psi-mi:pol3(display_short)|uniprotkb:pold(gene name synonym)|uniprotkb:SPBC336.04(orf name) psi-mi:dpod2_schpo(display_long)|uniprotkb:cdc1(gene name)|psi-mi:cdc1(display_short)|uniprotkb:SPAC27E2.05(orf name) psi-mi:"MI:0096"(pull down) Sanchez et al. (2004) pubmed:15173383|imex:IM-19112 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-865285|imex:IM-19112-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596124.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR025687|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|ensemblfungi:SPBC336.04(gene)|ensemblfungi:SPBC336.04.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606 interpro:IPR024826|refseq:NP_594406.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR040663|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR041863|ensemblfungi:SPAC27E2.05(gene)|ensemblfungi:SPAC27E2.05.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0051301"(cell division)|go:"GO:1903459"(mitotic DNA replication lagging strand elongation)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|reactome:R-SPO-174437|reactome:R-SPO-5358565|reactome:R-SPO-5358606 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/02/22 2014/10/16 rogid:+fzXa8W77qXirKXf5Ydzy7GE7ts284812 rogid:WcVki8A+hnyld55ylIQ4PeDhOuk284812 intact-crc:26917E1F034AE90E|rigid:Hz1LUVb87NGONmuJDSJc3gux8cc false his tag:n-n|necessary binding region:1017-1085 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)