#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25815	uniprotkb:P23297	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1110894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:9FFE2546C999F7F3|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23297	uniprotkb:P23297	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1110904	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	figure legend:1 A|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/13	2014/10/16	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:6F9ACA842DC03532|rigid:2LbF+5YDCaBK7CrD8bifDbz1uRI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P25815	uniprotkb:P23297	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1110925	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	figure legend:1 B, 6|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:C242F49F444DD19A|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	-	mutation disrupting interaction:12-12,16-16,72-72|mutation disrupting interaction:16-16	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25815	uniprotkb:P25815	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1110933	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	go:"GO:0042803"(protein homodimerization activity)	-	-	figure legend:1 B, 6|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	intact-crc:48AA99E0DE41F649|rigid:eJ4ZR1DenxAqnvTgICp+pR05KfY	false	mutation disrupting interaction:11-11,12-12|mutation disrupting interaction:15-15|mutation disrupting interaction:71-71|mutation disrupting interaction:74-74|mutation disrupting interaction:74-74|mutation disrupting interaction:75-75|mutation disrupting interaction:76-76|mutation disrupting interaction:75-75,76-76	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25815	uniprotkb:P23297	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1149999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	figure legend:1 B, 6|comment:These results suggest that the interface for the S100P-S100A1 interaction is similar but not identical to the S100P-S100P interface.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:26F94A97C057B1C5|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	mutation disrupting interaction:11-11,12-12|mutation disrupting interaction:15-15|mutation disrupting interaction:71-71|mutation disrupting interaction:74-74|mutation disrupting interaction:74-74|mutation disrupting interaction:75-75|mutation decreasing interaction:75-75,76-76	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25815	uniprotkb:P23297	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1110996	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	stimulant:The presence of Ca2+ increases the association rate constant. In the absence of Ca2+, the association rate constant was 30-50-fold slower. Also the Kb is lower in the presence of Ca2+.|kinetics:The Kd in the presence of Ca2+ is 1.4E-8 but in the absence of Ca2+ it is 1.1E-6.|figure legend:2 E-H, Table 1|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:CE827563203B3710|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25815	uniprotkb:P35579	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1149105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N	-	-	-	inhibition:rhS100A1 has an inhibitory effect on the binding of rhS100P to the immobilized rhC-MHC-IIA.|figure legend:5|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/13	2014/10/16	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	intact-crc:67A3BE3AE45A8E80|rigid:fHfS2oaOl0xm6veo0S2okVWW2ro	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23297	uniprotkb:P25815	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1148974	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	-	-	-	figure legend:4 A, B, D|caution:The images show whole cells and the colocalization appears to be throughout the whole cell and not localized to any specific region.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2006/10/13	2014/10/16	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	intact-crc:EEF0986A867496E8|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	fluorescent protein tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23297	uniprotkb:P25815	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1148999	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type)	-	-	-	figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/10/13	2014/10/16	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606	intact-crc:D2B40A4ECB464C2E|rigid:FLUhDZZTgU07judUHQaWIjjtM4U	false	fluorescent protein tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23297	uniprotkb:P23297	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	intact:EBI-743686|uniprotkb:Q5T7Y3|uniprotkb:B2R5D9|ensembl:ENSP00000292169	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:s10a1_human(display_long)|uniprotkb:S100 calcium-binding protein A1(gene name synonym)|uniprotkb:S-100 protein subunit alpha(gene name synonym)|uniprotkb:S-100 protein alpha chain(gene name synonym)|uniprotkb:S100A1(gene name)|psi-mi:S100A1(display_short)|uniprotkb:S100A(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Wang et al. (2004)	pubmed:15171681	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1149008	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	refseq:NP_006262.1|ensembl:ENSG00000160678(gene)|ensembl:ENST00000292169(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051117"(ATPase binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028486|mint:P23297|rcsb pdb:2L0P|rcsb pdb:2LHL|rcsb pdb:2LLS|rcsb pdb:2LLT|rcsb pdb:2LLU|rcsb pdb:2LP2|rcsb pdb:2LP3|rcsb pdb:2LUX|rcsb pdb:2M3W|rcsb pdb:5K89|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|interpro:IPR018247	-	-	-	figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2006/10/13	2014/10/16	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	rogid:cELa51qDGFnYHPBnpUhMDGYPfOk9606	intact-crc:2ED013B548E8EDDA|rigid:2LbF+5YDCaBK7CrD8bifDbz1uRI	false	fluorescent protein tag:c-c	fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)