#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49354	uniprotkb:P49356	intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423	intact:EBI-602349|uniprotkb:B2RDX6|uniprotkb:B4E1A0|ensembl:ENSP00000246166	psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short)	psi-mi:fntb_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:FNTB(gene name)|psi-mi:FNTB(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Reid et al. (2004)	pubmed:15170324	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1039209|rcsb pdb:1SA4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002	refseq:NP_002019.1|refseq:NP_001189487.1|ensembl:ENSG00000257365(gene)|ensembl:ENST00000246166(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|mint:P49356|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-2514859|reactome:R-HSA-9648002|go:"GO:0005965"(protein farnesyltransferase complex)	-	-	-	assembly:dimeric, multimeric|3d-r-factors:working 83.400%, free 80.500%|3d-resolution:2.1A|dataset:Cancer - Interactions investigated in the context of cancer|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606	rogid:ye1bL25dNbpl0e1solLbDb5CaX49606	intact-crc:B3EBAA80AA22D3F6|rigid:xXmkg2jpPCbiEyvZuMFlPhE46zg	false	sufficient binding region:1-379	sufficient binding region:1-437	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04631	uniprotkb:Q02293	intact:EBI-602447	intact:EBI-602454|ensembl:ENSRNOP00000010588	psi-mi:fnta_rat(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:Fnta(gene name)|psi-mi:Fnta(display_short)	psi-mi:fntb_rat(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:Fntb(gene name)|psi-mi:Fntb(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Reid et al. (2004)	pubmed:15170324	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1039220|rcsb pdb:1SA5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2625|refseq:NP_036979.1|reactome:R-RNO-9648002|reactome:R-RNO-111465|reactome:R-RNO-2514859|dip:DIP-6131N|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1FPP|rcsb pdb:1FT1|rcsb pdb:1FT2|rcsb pdb:1FTI|rcsb pdb:1HZ7|rcsb pdb:1JCR|rcsb pdb:1JCS|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1KZR|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:1N94|rcsb pdb:1N95|rcsb pdb:1N9A|rcsb pdb:1NI1|rcsb pdb:1NL4|rcsb pdb:1O1R|rcsb pdb:1O1S|rcsb pdb:1O1T|rcsb pdb:1O5M|rcsb pdb:1QBQ|rcsb pdb:1QE2|rcsb pdb:1S64|rcsb pdb:1SA5|rcsb pdb:1TN7|rcsb pdb:1TN8|rcsb pdb:1TNB|rcsb pdb:1TNO|rcsb pdb:1TNU|rcsb pdb:1TNY|rcsb pdb:1TNZ|rcsb pdb:1X81|rcsb pdb:2BED|rcsb pdb:2FTI|rcsb pdb:2R2L|rcsb pdb:2ZIR|rcsb pdb:2ZIS|rcsb pdb:3DPY|rcsb pdb:3E30|rcsb pdb:3E32|rcsb pdb:3E33|rcsb pdb:3E34|rcsb pdb:3EU5|rcsb pdb:3EUV|rcsb pdb:3FTI|rcsb pdb:3KSL|rcsb pdb:3KSQ|rcsb pdb:3PZ4|rcsb pdb:4GTM|rcsb pdb:4GTO|rcsb pdb:4GTP|rcsb pdb:4GTQ|rcsb pdb:4GTR	ensembl:ENSRNOG00000007660(gene)|ensembl:ENSRNOT00000010588(transcript)|go:"GO:0004311"(farnesyltranstransferase activity)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0034097"(response to cytokine)|rgd:620119|refseq:NP_742031.1|dip:DIP-6132N|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1FPP|rcsb pdb:1FT1|rcsb pdb:1FT2|rcsb pdb:1FTI|rcsb pdb:1HZ7|rcsb pdb:1JCR|rcsb pdb:1JCS|rcsb pdb:1KZO|rcsb pdb:1KZP|go:"GO:0042060"(wound healing)|rcsb pdb:1KZR|rcsb pdb:1N94|rcsb pdb:1N95|rcsb pdb:1N9A|rcsb pdb:1NI1|rcsb pdb:1NL4|rcsb pdb:1O1R|rcsb pdb:1O1S|rcsb pdb:1O1T|rcsb pdb:1O5M|rcsb pdb:1QBQ|rcsb pdb:1QE2|rcsb pdb:1SA5|rcsb pdb:1TN7|rcsb pdb:1TN8|rcsb pdb:1X81|rcsb pdb:2BED|rcsb pdb:2FTI|rcsb pdb:2R2L|rcsb pdb:2ZIR|rcsb pdb:2ZIS|rcsb pdb:3DPY|rcsb pdb:3E30|rcsb pdb:3E32|rcsb pdb:3E33|rcsb pdb:3E34|rcsb pdb:3EU5|rcsb pdb:3EUV|rcsb pdb:3FTI|rcsb pdb:3KSL|rcsb pdb:3KSQ|rcsb pdb:4GTM|rcsb pdb:4GTO|rcsb pdb:4GTP|rcsb pdb:4GTQ|rcsb pdb:4GTR|reactome:R-RNO-2514859|reactome:R-RNO-9648002	-	-	-	assembly:dimeric, multimeric|3d-r-factors:working 81.200%, free 77.500%|3d-resolution:2.6A|dataset:Cancer - Interactions investigated in the context of cancer|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:UqizMu5QoGM8WNj6siMYHNrE41Y10116	rogid:kKCkAYNev/B1QHIQnWf0hZLviAg10116	intact-crc:E5074E337D367318|rigid:xc1Q/7Kea5mWsuJ+M0yC41IQabw	false	sufficient binding region:1-377	sufficient binding region:1-437	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)