#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13936	uniprotkb:Q8VGC3	intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0	intact:EBI-1038896|uniprotkb:Q811Q6|uniprotkb:Q811Q7|uniprotkb:Q91ZJ8|uniprotkb:Q9QUU7	psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)	psi-mi:cacb2_rat(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Van et al. (2004)	pubmed:15141227	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1038938|rcsb pdb:1T0J	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N	rgd:67385|refseq:NP_446303.1|refseq:XP_006254360.1|refseq:XP_006254365.1|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|rcsb pdb:1T0H|rcsb pdb:1T0J|rcsb pdb:3JBR|rcsb pdb:5V2P|rcsb pdb:5V2Q|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|dip:DIP-29590N|reactome:R-RNO-112308|reactome:R-RNO-422356|reactome:R-RNO-5576892|reactome:R-RNO-5576893	-	-	-	assembly:trimeric, multimeric|3d-r-factors:working 80.0%, free 75.800%|3d-resolution:2A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2019/04/16	rogid:dhWcWUTulWYd/nQtGorjr481/XA9606	rogid:9wSCxOrytT27F1xnUjcdrFQtn4I10116	intact-crc:A5F5F0077968897E|rigid:u/jywVIC5CKmD0TbVsq2EhKe4hc	false	sufficient binding region:428-445	sufficient binding region:254-476	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13936	uniprotkb:Q8VGC3	intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0	intact:EBI-1038896|uniprotkb:Q811Q6|uniprotkb:Q811Q7|uniprotkb:Q91ZJ8|uniprotkb:Q9QUU7	psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)	psi-mi:cacb2_rat(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Van et al. (2004)	pubmed:15141227	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1038938|rcsb pdb:1T0J	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N	rgd:67385|refseq:NP_446303.1|refseq:XP_006254360.1|refseq:XP_006254365.1|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|rcsb pdb:1T0H|rcsb pdb:1T0J|rcsb pdb:3JBR|rcsb pdb:5V2P|rcsb pdb:5V2Q|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|dip:DIP-29590N|reactome:R-RNO-112308|reactome:R-RNO-422356|reactome:R-RNO-5576892|reactome:R-RNO-5576893	-	-	-	assembly:trimeric, multimeric|3d-r-factors:working 80.0%, free 75.800%|3d-resolution:2A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2019/04/16	rogid:dhWcWUTulWYd/nQtGorjr481/XA9606	rogid:9wSCxOrytT27F1xnUjcdrFQtn4I10116	intact-crc:A5F5F0077968897E|rigid:u/jywVIC5CKmD0TbVsq2EhKe4hc	false	sufficient binding region:428-445	sufficient binding region:68-196	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)