#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01138	uniprotkb:P07174	intact:EBI-1028250|uniprotkb:Q6FHA0|uniprotkb:Q96P60|uniprotkb:Q9P2Q8|uniprotkb:Q9UKL8|uniprotkb:A1A4E5|ensembl:ENSP00000358525|ensembl:ENSP00000502380|ensembl:ENSP00000502831|ensembl:ENSP00000505694|ensembl:ENSP00000506492|ensembl:ENSP00000506569|ensembl:ENSP00000505558	intact:EBI-1038810	psi-mi:ngf_human(display_long)|uniprotkb:NGF(gene name)|psi-mi:NGF(display_short)|uniprotkb:NGFB(gene name synonym)	psi-mi:tnr16_rat(display_long)|uniprotkb:Ngfr(gene name)|psi-mi:Ngfr(display_short)|uniprotkb:Tnfrsf16(gene name synonym)|uniprotkb:Low-affinity nerve growth factor receptor(gene name synonym)|uniprotkb:Gp80-LNGFR(gene name synonym)|uniprotkb:p75 ICD(gene name synonym)|uniprotkb:Low affinity neurotrophin receptor p75NTR(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	He et al. (2004)	pubmed:15131306	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1038827|rcsb pdb:1SG1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002497.2|ensembl:ENSG00000134259(gene)|ensembl:ENST00000369512(transcript)|ensembl:ENST00000675637(transcript)|ensembl:ENST00000676038(transcript)|ensembl:ENST00000679806(transcript)|ensembl:ENST00000680116(transcript)|ensembl:ENST00000680540(transcript)|ensembl:ENST00000680752(transcript)|go:"GO:0005163"(nerve growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007613"(memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008083"(growth factor activity)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021675"(nerve development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031904"(endosome lumen)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0038177"(death receptor agonist activity)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR002072(Nerve growth factor)|interpro:IPR019846|interpro:IPR020408|interpro:IPR020425|interpro:IPR020437|rcsb pdb:1SG1|rcsb pdb:1WWW|rcsb pdb:2IFG|rcsb pdb:4EDW|rcsb pdb:4EDX|rcsb pdb:4ZBN|rcsb pdb:5JZ7|rcsb pdb:6YW8|reactome:R-HSA-167021|reactome:R-HSA-167044|interpro:IPR029034|reactome:R-HSA-167060|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-177504|reactome:R-HSA-187042|reactome:R-HSA-187706|reactome:R-HSA-193648|reactome:R-HSA-193670|reactome:R-HSA-193681|reactome:R-HSA-198203|reactome:R-HSA-198745|reactome:R-HSA-205017|reactome:R-HSA-205025|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-209563|refseq:XP_006710726.1|dip:DIP-5712N	rgd:3177|refseq:NP_036742.2|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005035"(death receptor activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0007165"(signal transduction)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0021675"(nerve development)|go:"GO:0030135"(coated vesicle)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009986"(cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035907"(dorsal aorta development)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042488"(positive regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051799"(negative regulation of hair follicle development)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0070678"(preprotein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022325|interpro:IPR034046|interpro:IPR041448|rcsb pdb:1NGR|rcsb pdb:1SG1|rcsb pdb:2MIC|rcsb pdb:2MJO|rcsb pdb:3BUK|rcsb pdb:3IJ2|rcsb pdb:4F42|rcsb pdb:4F44|reactome:R-RNO-193634|reactome:R-RNO-193692|reactome:R-RNO-205017|reactome:R-RNO-205025|reactome:R-RNO-205043|reactome:R-RNO-209543|reactome:R-RNO-209560|reactome:R-RNO-209563|go:"GO:0051897"(positive regulation of protein kinase B signaling)|mint:P07174|dip:DIP-5715N	-	-	-	assembly:trimeric, multimeric|3d-r-factors:working 75.700%, free 73.100%|3d-resolution:2.4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:qUmDPZg27gpyP0gOpOpUZJyV7mI9606	rogid:lscumOKfwxDCsoAs1EZfp6iFwz410116	intact-crc:08DC2E7F041388D2|rigid:5tgb2buk4peZzwe7Aw+BJkBmsyw	false	sufficient binding region:122-241	sufficient binding region:30-190	2	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)