#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54763	uniprotkb:O08543	intact:EBI-537711|uniprotkb:Q9QVY4|uniprotkb:Q62213|uniprotkb:A3KG00|uniprotkb:A3KG01|uniprotkb:A3KG02|uniprotkb:A3KG89|uniprotkb:A3KG90|uniprotkb:Q6GTQ7|uniprotkb:Q6P5F1|ensembl:ENSMUSP00000101471	intact:EBI-1038734|uniprotkb:O08544|ensembl:ENSMUSP00000076115	psi-mi:ephb2_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor EPH-3(gene name synonym)|uniprotkb:Neural kinase(gene name synonym)|uniprotkb:Nuk receptor tyrosine kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor SEK-3(gene name synonym)|uniprotkb:Ephb2(gene name)|psi-mi:Ephb2(display_short)|uniprotkb:Epth3(gene name synonym)|uniprotkb:Nuk(gene name synonym)|uniprotkb:Sek3(gene name synonym)	psi-mi:efna5_mouse(display_long)|uniprotkb:Efna5(gene name)|psi-mi:Efna5(display_short)|uniprotkb:Epl7(gene name synonym)|uniprotkb:Eplg7(gene name synonym)|uniprotkb:Lerk7(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 7(gene name synonym)|uniprotkb:AL-1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Himanen et al. (2004)	pubmed:15107857	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1038760|rcsb pdb:1SHW	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001277682.1|refseq:NP_034272.1|refseq:XP_006538594.1|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0001655"(urogenital system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016310"(phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042113"(B cell activation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0050878"(regulation of body fluid levels)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0005003"(ephrin receptor activity)|interpro:IPR011009(Protein kinase-like)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR011641(GCC2 and GCC3)|go:"GO:0106028"(neuron projection retraction)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|go:"GO:1904782"(negative regulation of NMDA glutamate receptor activity)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034238|interpro:IPR036116|mint:P54763|rcsb pdb:1JPA|rcsb pdb:1KGY|rcsb pdb:1NUK|interpro:IPR000719(Protein kinase, core)|rcsb pdb:1SHW|rcsb pdb:2HEN|rcsb pdb:3ETP|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|reactome:R-MMU-2682334|interpro:IPR003961(Fibronectin, type III)|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|ensembl:ENSMUSG00000028664(gene)|ensembl:ENSMUST00000105845(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001525"(angiogenesis)|dip:DIP-34917N	refseq:NP_034239.1|refseq:NP_997537.1|ensembl:ENSMUSG00000048915(gene)|ensembl:ENSMUST00000076840(transcript)|go:"GO:0005169"(neurotrophin TRKB receptor binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0007411"(axon guidance)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|go:"GO:0007420"(brain development)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|rcsb pdb:1SHW|rcsb pdb:1SHX|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665	-	-	-	assembly:dimeric, multimeric|3d-r-factors:working 74.200%, free 69.500%|3d-resolution:2.2A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2015/11/10	rogid:QgDJW2yhMS13Eb5l3DR03T814gI10090	rogid:nZHNk76smhusfT9PascYKOLnRjw10090	intact-crc:1D8E5DBBB7F8BE3A|rigid:9Sj+dt/h4cEz02QG4+LpVPBCaIw	false	sufficient binding region:19-199	sufficient binding region:28-165	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)