#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912679|imex:IM-18987-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:DA0CC124402AFA8E|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false sufficient binding region:22-89 sufficient binding region:?-? - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912693|imex:IM-18987-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:4D9226AF503137E3|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false sufficient binding region:21-129 sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43889-2 uniprotkb:P51681 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912701|imex:IM-18987-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606 intact-crc:9715B7911AE176E4|rigid:/+F0UQCUyLqHyDXg7apmlnN4XyM false sufficient binding region:21-129 sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912772|imex:IM-18987-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:A93E29320C0F1F22|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false sufficient binding region:21-243 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912817|imex:IM-18987-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:41601BB983A8CF1F|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false sufficient binding region:21-260|ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-912849|imex:IM-18987-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:B85850A02F4AE88E|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false sufficient binding region:21-260|ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-912976|imex:IM-18987-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:7B7064AF30941458|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43889-2 uniprotkb:P32246 intact:EBI-625022|ensembl:ENSP00000342136 intact:EBI-608322|ensembl:ENSP00000296140|uniprotkb:Q86VA9 psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym) psi-mi:ccr1_human(display_long)|uniprotkb:Macrophage inflammatory protein 1-alpha receptor(gene name synonym)|uniprotkb:RANTES-R(gene name synonym)|uniprotkb:HM145(gene name synonym)|uniprotkb:LD78 receptor(gene name synonym)|uniprotkb:CCR1(gene name)|psi-mi:CCR1(display_short)|uniprotkb:CMKBR1(gene name synonym)|uniprotkb:CMKR1(gene name synonym)|uniprotkb:SCYAR1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Ko et al. (2004) pubmed:15001559|imex:IM-18987 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-913018|imex:IM-18987-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent) ensembl:ENSG00000163823(gene)|ensembl:ENST00000296140(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009611"(response to wounding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0035717"("chemokine (C-C motif) ligand 7 binding")|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002236(C-C chemokine receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P32246|rcsb pdb:1Y5D|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|interpro:IPR034321|refseq:NP_001286.1|dip:DIP-5832N - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-periph_blood_leukoc)|taxid:9606(Homo sapiens peripheral blood leukocytes) - 2006/03/28 2014/10/16 rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606 rogid:m8grSofEywwJfUzrRCNNjYrq6ps9606 intact-crc:E31395230292AD3D|rigid:eIF5OdordRa0fHAjkNGc/swApvQ false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)