#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P52198	uniprotkb:Q8R511	intact:EBI-1111436|uniprotkb:O00690|uniprotkb:O00734|uniprotkb:Q5U0P6|uniprotkb:Q99535|uniprotkb:A8K2D4|ensembl:ENSP00000466680	intact:EBI-1111424|uniprotkb:Q75UE2|uniprotkb:Q75UE3|uniprotkb:Q75UE4|uniprotkb:Q75UE5|uniprotkb:Q75UE6	psi-mi:rnd2_human(display_long)|uniprotkb:RND2(gene name)|psi-mi:RND2(display_short)|uniprotkb:ARHN(gene name synonym)|uniprotkb:RHO7(gene name synonym)|uniprotkb:Rho family GTPase 2(gene name synonym)|uniprotkb:Rnd2(gene name synonym)|uniprotkb:Rho-related GTP-binding protein Rho7(gene name synonym)	psi-mi:fnbp1_rat(display_long)|uniprotkb:Fnbp1(gene name)|psi-mi:Fnbp1(display_short)|uniprotkb:Formin-binding protein 17(gene name synonym)|uniprotkb:Rapostlin(gene name synonym)|uniprotkb:Fbp17(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111422|imex:IM-19257-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048672"(positive regulation of collateral sprouting)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041842|reactome:R-HSA-9696270|ensembl:ENSG00000108830(gene)|ensembl:ENST00000587250(transcript)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|refseq:NP_005431.1	interpro:IPR027267|interpro:IPR028532|rgd:621350|refseq:NP_620269.1|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008289"(lipid binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9696270|interpro:IPR035492|interpro:IPR037449|mint:Q8R511|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)	-	-	-	figure legend:Fig. 2|comment:The interaction is specific to the GTP-bound form of RND2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/23	2014/10/16	rogid:aQqi1/N5CGBh7raPP+lUvsS8CqA9606	rogid:Ryvj22B76jaT6vpwvnmlbm5k/Yk10116	intact-crc:5392103512B75A54|rigid:6IrGiGqrAN5hXrl57OW0PoXZiis	false	glutathione s tranferase tag:n-n	glutathione s tranferase tag:n-n|sufficient binding region:329-616	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O43157	uniprotkb:Q92730	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440|ensembl:ENSP00000351338	intact:EBI-448618|uniprotkb:A8K9P7|ensembl:ENSP00000308461	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:rnd1_human(display_long)|uniprotkb:RND1(gene name)|psi-mi:RND1(display_short)|uniprotkb:RHO6(gene name synonym)|uniprotkb:Rho family GTPase 1(gene name synonym)|uniprotkb:Rnd1(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111479|imex:IM-19257-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|refseq:NP_001123554.1|refseq:NP_002664.2|ensembl:ENSG00000164050(gene)|ensembl:ENST00000296440(transcript)|ensembl:ENST00000358536(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1900220"(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:O43157|refseq:XP_016862120.1|dip:DIP-36742N	refseq:NP_055285.1|dip:DIP-36741N|ensembl:ENSG00000172602(gene)|ensembl:ENST00000309739(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2CLS|rcsb pdb:2REX|rcsb pdb:3Q3J|reactome:R-HSA-399955|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-9696273	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/23	2014/10/16	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	rogid:phz3xjUx3hNvqd/BE+e6Zjb2n7g9606	intact-crc:FE3B3E66B3CE10CC|rigid:qK64kTqrAxfMYsIWl9Xa4Fm2EkE	false	glutathione s tranferase tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P61587	uniprotkb:O43157	intact:EBI-1111534|uniprotkb:P52199|uniprotkb:D3DP95|ensembl:ENSP00000263895|ensembl:ENSP00000364886	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440|ensembl:ENSP00000351338	psi-mi:rnd3_human(display_long)|uniprotkb:RND3(gene name)|psi-mi:RND3(display_short)|uniprotkb:ARHE(gene name synonym)|uniprotkb:RHO8(gene name synonym)|uniprotkb:RHOE(gene name synonym)|uniprotkb:Rho family GTPase 3(gene name synonym)|uniprotkb:Rnd3(gene name synonym)|uniprotkb:Rho-related GTP-binding protein Rho8(gene name synonym)|uniprotkb:Protein MemB(gene name synonym)	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:"MI:0400"(affinity technology)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111547|imex:IM-19257-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005159.1|refseq:NP_001241667.1|ensembl:ENSG00000115963(gene)|ensembl:ENST00000263895(transcript)|ensembl:ENST00000375734(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041843|rcsb pdb:1M7B|rcsb pdb:2V55|rcsb pdb:4BG6|reactome:R-HSA-9696264|mint:P61587	rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|refseq:NP_001123554.1|refseq:NP_002664.2|ensembl:ENSG00000164050(gene)|ensembl:ENST00000296440(transcript)|ensembl:ENST00000358536(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1900220"(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:O43157|refseq:XP_016862120.1|dip:DIP-36742N	-	-	-	figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/23	2014/10/16	rogid:nRE3V8nu01Om6bk+I97m3IubAJg9606	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	intact-crc:8C9797781583C9D8|rigid:iklXdnz7U0y4GNB+hb8ldEAx5zw	false	glutathione s tranferase tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q8R511	uniprotkb:O00401	intact:EBI-1111424|uniprotkb:Q75UE2|uniprotkb:Q75UE3|uniprotkb:Q75UE4|uniprotkb:Q75UE5|uniprotkb:Q75UE6	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	psi-mi:fnbp1_rat(display_long)|uniprotkb:Fnbp1(gene name)|psi-mi:Fnbp1(display_short)|uniprotkb:Formin-binding protein 17(gene name synonym)|uniprotkb:Rapostlin(gene name synonym)|uniprotkb:Fbp17(gene name synonym)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:"MI:0096"(pull down)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111563|imex:IM-19257-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|interpro:IPR028532|rgd:621350|refseq:NP_620269.1|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008289"(lipid binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9696270|interpro:IPR035492|interpro:IPR037449|mint:Q8R511|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N	-	-	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/23	2014/10/16	rogid:Ryvj22B76jaT6vpwvnmlbm5k/Yk10116	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:6BE63AEF25FEC15B|rigid:yqEEJ/BQa7btDufzjzwsYz44DPM	false	glutathione s tranferase tag:n-n|sufficient binding region:553-616	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P52198	uniprotkb:Q8R511	intact:EBI-1111436|uniprotkb:O00690|uniprotkb:O00734|uniprotkb:Q5U0P6|uniprotkb:Q99535|uniprotkb:A8K2D4|ensembl:ENSP00000466680	intact:EBI-1111424|uniprotkb:Q75UE2|uniprotkb:Q75UE3|uniprotkb:Q75UE4|uniprotkb:Q75UE5|uniprotkb:Q75UE6	psi-mi:rnd2_human(display_long)|uniprotkb:RND2(gene name)|psi-mi:RND2(display_short)|uniprotkb:ARHN(gene name synonym)|uniprotkb:RHO7(gene name synonym)|uniprotkb:Rho family GTPase 2(gene name synonym)|uniprotkb:Rnd2(gene name synonym)|uniprotkb:Rho-related GTP-binding protein Rho7(gene name synonym)	psi-mi:fnbp1_rat(display_long)|uniprotkb:Fnbp1(gene name)|psi-mi:Fnbp1(display_short)|uniprotkb:Formin-binding protein 17(gene name synonym)|uniprotkb:Rapostlin(gene name synonym)|uniprotkb:Fbp17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111579|imex:IM-19257-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048672"(positive regulation of collateral sprouting)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041842|reactome:R-HSA-9696270|ensembl:ENSG00000108830(gene)|ensembl:ENST00000587250(transcript)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|refseq:NP_005431.1	interpro:IPR027267|interpro:IPR028532|rgd:621350|refseq:NP_620269.1|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008289"(lipid binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9696270|interpro:IPR035492|interpro:IPR037449|mint:Q8R511|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)	-	-	-	figure legend:Fig. 5B, 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/10/23	2014/10/16	rogid:aQqi1/N5CGBh7raPP+lUvsS8CqA9606	rogid:Ryvj22B76jaT6vpwvnmlbm5k/Yk10116	intact-crc:0A547431864A660B|rigid:6IrGiGqrAN5hXrl57OW0PoXZiis	false	mutation increasing interaction:16-16	myc tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R511	uniprotkb:O00401	intact:EBI-1111424|uniprotkb:Q75UE2|uniprotkb:Q75UE3|uniprotkb:Q75UE4|uniprotkb:Q75UE5|uniprotkb:Q75UE6	intact:EBI-957615|ensembl:ENSP00000223023|uniprotkb:Q7Z746|uniprotkb:A1JUI9	psi-mi:fnbp1_rat(display_long)|uniprotkb:Fnbp1(gene name)|psi-mi:Fnbp1(display_short)|uniprotkb:Formin-binding protein 17(gene name synonym)|uniprotkb:Rapostlin(gene name synonym)|uniprotkb:Fbp17(gene name synonym)	psi-mi:wasl_human(display_long)|uniprotkb:WASL(gene name)|psi-mi:WASL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kakimoto et al. (2004)	pubmed:14732713|imex:IM-19257	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1111597|imex:IM-19257-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|interpro:IPR028532|rgd:621350|refseq:NP_620269.1|interpro:IPR031160|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008289"(lipid binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9696270|interpro:IPR035492|interpro:IPR037449|mint:Q8R511|interpro:IPR036028|interpro:IPR011072(HR1 rho-binding repeat)	go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0009617"(response to bacterium)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|rcsb pdb:2FF3|rcsb pdb:2LNH|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:2VCP|rcsb pdb:4CC2|rcsb pdb:4CC7|reactome:R-HSA-2029482|reactome:R-HSA-203641|reactome:R-HSA-373753|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013424|reactome:R-HSA-9664422|ensembl:ENSG00000106299(gene)|ensembl:ENST00000223023(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|mint:O00401|go:"GO:0005634"(nucleus)|refseq:NP_003932.3|dip:DIP-29042N	-	-	-	figure legend:Fig. 5B, 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/10/23	2014/10/16	rogid:Ryvj22B76jaT6vpwvnmlbm5k/Yk10116	rogid:PinEPh47IRuCgiaJJZqStRhIAGQ9606	intact-crc:5D0C1FB0DD008D9D|rigid:yqEEJ/BQa7btDufzjzwsYz44DPM	false	sufficient binding region:2-552|myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)