#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02821 uniprotkb:P32499 intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W intact:EBI-12401|uniprotkb:Q06130|ensemblfungi:YLR335W|uniprotkb:D6VYX5 psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym) psi-mi:nup2_yeast(display_long)|uniprotkb:NUP2(gene name)|psi-mi:NUP2(display_short)|uniprotkb:YLR335W(locus name)|uniprotkb:L8300.9(orf name)|uniprotkb:Nuclear pore protein NUP2(gene name synonym)|uniprotkb:p95(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Matsuura et al. (2003) pubmed:14532109 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1037295|rcsb pdb:1UN0 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94 refseq:NP_013439.1|sgd:S000004327|ensemblfungi:YLR335W(gene)|ensemblfungi:YLR335W_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|rcsb pdb:1UN0|rcsb pdb:2C1T|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|mint:P32499|dip:DIP-859N - crc64:8D3A0CB76F2E7C00 crc64:467210F14FA73311 assembly:tetrameric, multimeric|3d-resolution:2.6A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292 rogid:n0JzHu75yD2leLZP5A5pkbeEXXI559292 intact-crc:CDE5A270C5B90EAA|rigid:JCiYpJJpdCpBcuTTOZ6OGH+N79w false sufficient binding region:88-530 sufficient binding region:1-51 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)