#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12694	uniprotkb:P21953	intact:EBI-1029053|uniprotkb:Q16034|uniprotkb:Q16472|uniprotkb:B4DP47|uniprotkb:E7EW46|ensembl:ENSP00000269980	intact:EBI-1029067|uniprotkb:Q5T2J3|ensembl:ENSP00000318351|ensembl:ENSP00000348880|uniprotkb:Q9BQL0	psi-mi:odba_human(display_long)|uniprotkb:BCKDHA(gene name)|psi-mi:BCKDHA(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)	psi-mi:odbb_human(display_long)|uniprotkb:BCKDHB(gene name)|psi-mi:BCKDHB(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component beta chain(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wynn et al. (2003)	pubmed:12902323|mint:MINT-5216602	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1036952|rcsb pdb:1OLS	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000700.1|ensembl:ENSG00000248098(gene)|ensembl:ENST00000269980(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR034616|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|refseq:NP_001158255.1|dip:DIP-6146N	refseq:NP_000047.1|refseq:NP_898871.1|ensembl:ENST00000356489(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR029061|interpro:IPR033248|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|ensembl:ENSG00000083123(gene)|ensembl:ENST00000320393(transcript)|refseq:NP_001305904.1|dip:DIP-6147N	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 82.800%, free 80.100%|3d-resolution:1.85A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:dfjLnS4YI8gwCQljkXL3W24I/DY9606	rogid:2KgCDcF9/M5ZI8/2WV4bU1Qmnvk9606	intact-crc:226D6AEA2D69D875|rigid:Rdk4w9J/UoyJSCnlaglMuEmeQn4	false	sufficient binding region:46-445	sufficient binding region:51-392	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21953	uniprotkb:P12694	intact:EBI-1029067|uniprotkb:Q5T2J3|ensembl:ENSP00000318351|ensembl:ENSP00000348880|uniprotkb:Q9BQL0	intact:EBI-1029053|uniprotkb:Q16034|uniprotkb:Q16472|uniprotkb:B4DP47|uniprotkb:E7EW46|ensembl:ENSP00000269980	psi-mi:odbb_human(display_long)|uniprotkb:BCKDHB(gene name)|psi-mi:BCKDHB(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component beta chain(gene name synonym)	psi-mi:odba_human(display_long)|uniprotkb:BCKDHA(gene name)|psi-mi:BCKDHA(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wynn et al. (2003)	pubmed:12902323|mint:MINT-5216602	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1036963|rcsb pdb:1OLU	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000047.1|refseq:NP_898871.1|ensembl:ENST00000356489(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR029061|interpro:IPR033248|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|ensembl:ENSG00000083123(gene)|ensembl:ENST00000320393(transcript)|refseq:NP_001305904.1|dip:DIP-6147N	refseq:NP_000700.1|ensembl:ENSG00000248098(gene)|ensembl:ENST00000269980(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR034616|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|refseq:NP_001158255.1|dip:DIP-6146N	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 83.900%, free 80.0%|3d-resolution:1.9A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:2KgCDcF9/M5ZI8/2WV4bU1Qmnvk9606	rogid:dfjLnS4YI8gwCQljkXL3W24I/DY9606	intact-crc:BC27E93C1F5DE24A|rigid:Rdk4w9J/UoyJSCnlaglMuEmeQn4	false	sufficient binding region:51-392	sufficient binding region:46-445	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P12694	uniprotkb:P21953	intact:EBI-1029053|uniprotkb:Q16034|uniprotkb:Q16472|uniprotkb:B4DP47|uniprotkb:E7EW46|ensembl:ENSP00000269980	intact:EBI-1029067|uniprotkb:Q5T2J3|ensembl:ENSP00000318351|ensembl:ENSP00000348880|uniprotkb:Q9BQL0	psi-mi:odba_human(display_long)|uniprotkb:BCKDHA(gene name)|psi-mi:BCKDHA(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)	psi-mi:odbb_human(display_long)|uniprotkb:BCKDHB(gene name)|psi-mi:BCKDHB(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component beta chain(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wynn et al. (2003)	pubmed:12902323|mint:MINT-5216602	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1036974|rcsb pdb:1OLX	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000700.1|ensembl:ENSG00000248098(gene)|ensembl:ENST00000269980(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR034616|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|refseq:NP_001158255.1|dip:DIP-6146N	refseq:NP_000047.1|refseq:NP_898871.1|ensembl:ENST00000356489(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR029061|interpro:IPR033248|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|ensembl:ENSG00000083123(gene)|ensembl:ENST00000320393(transcript)|refseq:NP_001305904.1|dip:DIP-6147N	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 83.900%, free 78.600%|3d-resolution:2.25A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:dfjLnS4YI8gwCQljkXL3W24I/DY9606	rogid:2KgCDcF9/M5ZI8/2WV4bU1Qmnvk9606	intact-crc:3EFAA35DD268736B|rigid:Rdk4w9J/UoyJSCnlaglMuEmeQn4	false	sufficient binding region:46-445	sufficient binding region:51-392	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)