#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q76I89 uniprotkb:Q76I90 intact:EBI-1003779|uniprotkb:Q5ZLT8|ensembl:ENSGALP00000023851 intact:EBI-1003866|uniprotkb:Q5ZI77 psi-mi:ndc80_chick(display_long)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC1(gene name synonym)|uniprotkb:RCJMB04_4o15(orf name) psi-mi:nuf2_chick(display_long)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:RCJMB04_29i8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hori et al. (2003) pubmed:12829748 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1003958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_989808.2|refseq:XP_015133419.1|ensembl:ENSGALG00000014801(gene)|ensembl:ENSGALT00000023897(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008315"(G2/MI transition of meiotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 interpro:IPR005549(Nuf2)|refseq:NP_989809.2|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR038275 - - - figure legend:Fig. 1A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma) - 2006/09/01 2014/10/16 rogid:ycZJpt0dW1dpT5KZezlFJPI8Hpc9031 rogid:bVwoAFRXlIyJUMGoyh7IhybT70E9031 intact-crc:D6EF5E01B31CADAD|rigid:dosDjXIY5OLoWDsykJpNOq8sv60 false - green fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q76I89 uniprotkb:Q76I90 intact:EBI-1003779|uniprotkb:Q5ZLT8|ensembl:ENSGALP00000023851 intact:EBI-1003866|uniprotkb:Q5ZI77 psi-mi:ndc80_chick(display_long)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC1(gene name synonym)|uniprotkb:RCJMB04_4o15(orf name) psi-mi:nuf2_chick(display_long)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:RCJMB04_29i8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hori et al. (2003) pubmed:12829748 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1003962 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_989808.2|refseq:XP_015133419.1|ensembl:ENSGALG00000014801(gene)|ensembl:ENSGALT00000023897(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008315"(G2/MI transition of meiotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 interpro:IPR005549(Nuf2)|refseq:NP_989809.2|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR038275 - - - dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma) - 2006/09/01 2014/10/16 rogid:ycZJpt0dW1dpT5KZezlFJPI8Hpc9031 rogid:bVwoAFRXlIyJUMGoyh7IhybT70E9031 intact-crc:8EE61B61B47E92A3|rigid:dosDjXIY5OLoWDsykJpNOq8sv60 false green fluorescent protein tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q76I89 uniprotkb:Q76I90 intact:EBI-1003779|uniprotkb:Q5ZLT8|ensembl:ENSGALP00000023851 intact:EBI-1003866|uniprotkb:Q5ZI77 psi-mi:ndc80_chick(display_long)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC1(gene name synonym)|uniprotkb:RCJMB04_4o15(orf name) psi-mi:nuf2_chick(display_long)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:RCJMB04_29i8(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Hori et al. (2003) pubmed:12829748 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1003987 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_989808.2|refseq:XP_015133419.1|ensembl:ENSGALG00000014801(gene)|ensembl:ENSGALT00000023897(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008315"(G2/MI transition of meiotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|reactome:R-GGA-141444|reactome:R-GGA-2467813|reactome:R-GGA-2500257|reactome:R-GGA-5663220|reactome:R-GGA-68877|reactome:R-GGA-9648025 interpro:IPR005549(Nuf2)|refseq:NP_989809.2|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR038275 - - - figure legend:Fig. 1B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma) - 2006/09/01 2014/10/16 rogid:ycZJpt0dW1dpT5KZezlFJPI8Hpc9031 rogid:bVwoAFRXlIyJUMGoyh7IhybT70E9031 intact-crc:A58DFC50B38A2A92|rigid:dosDjXIY5OLoWDsykJpNOq8sv60 false red fluorescent protein tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q76I90 uniprotkb:O57392 intact:EBI-1003866|uniprotkb:Q5ZI77 intact:EBI-1003670 psi-mi:nuf2_chick(display_long)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:RCJMB04_29i8(orf name) psi-mi:o57392_chick(display_long)|uniprotkb:centoromere protein C(gene name)|psi-mi:centoromere protein C(display_short)|uniprotkb:CENP-C(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Hori et al. (2003) pubmed:12829748 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-1004004 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005549(Nuf2)|refseq:NP_989809.2|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR038275 interpro:IPR028386|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:NP_990382.1|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR028052|interpro:IPR025974|rcsb pdb:7BXT - - - figure legend:Fig. 2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma) - 2006/09/01 2014/10/16 rogid:bVwoAFRXlIyJUMGoyh7IhybT70E9031 rogid:9zTEK5l+PmWaxXBorOO3f7lDo5Q9031 intact-crc:9589C0AA5E1B1CFF|rigid:JDHfxJ4A2o59Nuj/02/CUp3/LMo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)