#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04004	uniprotkb:P05121	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-953978|ensembl:ENSP00000223095|uniprotkb:B7Z4S0|uniprotkb:F8WD53	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:pai1_human(display_long)|uniprotkb:Endothelial plasminogen activator inhibitor(gene name synonym)|uniprotkb:SERPINE1(gene name)|psi-mi:SERPINE1(display_short)|uniprotkb:PAI1(gene name synonym)|uniprotkb:PLANH1(gene name synonym)|uniprotkb:Serpin E1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Zhou et al. (2003)	pubmed:12808446|mint:MINT-5216470	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1036671|rcsb pdb:1OC0	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	ensembl:ENSG00000106366(gene)|ensembl:ENST00000223095(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035491"(positive regulation of leukotriene production involved in inflammatory response)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090399"(replicative senescence)|go:"GO:0097187"(dentinogenesis)|go:"GO:1901331"(positive regulation of odontoblast differentiation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1A7C|rcsb pdb:1B3K|interpro:IPR023795|rcsb pdb:1C5G|rcsb pdb:1DB2|rcsb pdb:1DVM|rcsb pdb:1DVN|rcsb pdb:1LJ5|rcsb pdb:1OC0|rcsb pdb:3CVM|rcsb pdb:3EOX|rcsb pdb:3PB1|rcsb pdb:3Q02|rcsb pdb:3Q03|rcsb pdb:3R4L|rcsb pdb:3UT3|rcsb pdb:4AQH|rcsb pdb:4G8O|rcsb pdb:4G8R|rcsb pdb:4IC0|rcsb pdb:5BRR|rcsb pdb:5ZLZ|rcsb pdb:6GWN|rcsb pdb:6GWP|rcsb pdb:6GWQ|rcsb pdb:6I8S|rcsb pdb:6ZRV|rcsb pdb:7AQF|rcsb pdb:7AQG|rcsb pdb:9PAI|reactome:R-HSA-114608|reactome:R-HSA-1368108|reactome:R-HSA-2173796|reactome:R-HSA-3000178|reactome:R-HSA-75205|refseq:NP_000593.1	-	-	-	assembly:dimeric, multimeric|3d-resolution:2.28A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:uKgGVfJUEf7zIyf5CgJGIf5TJco9606	intact-crc:77D486721596D9F1|rigid:E1e1rtgLV70zGdcY8MQT4b293RM	false	sufficient binding region:20-70	sufficient binding region:24-402	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)