#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04574 uniprotkb:P49342 intact:EBI-1036151|uniprotkb:Q8SPJ8|ensembl:ENSSSCP00025036836|ensembl:ENSSSCP00030015901|ensembl:ENSSSCP00035017837|ensembl:ENSSSCP00040046648|ensembl:ENSSSCP00045045985|ensembl:ENSSSCP00050013378|ensembl:ENSSSCP00055036144|ensembl:ENSSSCP00055036250|ensembl:ENSSSCP00060040612|ensembl:ENSSSCP00065041775|ensembl:ENSSSCP00070013531 intact:EBI-1036146 psi-mi:cpns1_pig(display_long)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym) psi-mi:ical_chlae(display_long)|uniprotkb:CAST(gene name)|psi-mi:CAST(display_short)|uniprotkb:Calpain inhibitor(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Todd et al. (2003) pubmed:12684003 taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1036165|rcsb pdb:1NX1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_999483.1|ensembl:ENSSSCT00025084678(transcript)|ensembl:ENSSSCT00030034851(transcript)|ensembl:ENSSSCT00035044573(transcript)|ensembl:ENSSSCG00025061681(gene)|ensembl:ENSSSCT00040103090(transcript)|ensembl:ENSSSCT00045065012(transcript)|ensembl:ENSSSCG00030024958(gene)|ensembl:ENSSSCT00050032028(transcript)|ensembl:ENSSSCT00055045351(transcript)|ensembl:ENSSSCT00055045479(transcript)|ensembl:ENSSSCG00035033634(gene)|ensembl:ENSSSCG00040074544(gene)|ensembl:ENSSSCG00045037628(gene)|ensembl:ENSSSCT00060093870(transcript)|ensembl:ENSSSCT00065095464(transcript)|ensembl:ENSSSCT00070016339(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|ensembl:ENSSSCG00050023744(gene)|ensembl:ENSSSCG00055023005(gene)|ensembl:ENSSSCG00060068749(gene)|ensembl:ENSSSCG00065069526(gene)|ensembl:ENSSSCG00070008417(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|rcsb pdb:1ALV|rcsb pdb:1ALW|rcsb pdb:1NX0|rcsb pdb:1NX1|rcsb pdb:1NX2|rcsb pdb:1NX3|rcsb pdb:4PHN|reactome:R-SSC-1474228|reactome:R-SSC-6809371 interpro:IPR001259(Proteinase inhibitor I27, calpastatin)|interpro:IPR026998|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity) - - - assembly:tetrameric, multimeric|3d-r-factors:working 79.200%, free 74.700%|3d-resolution:2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:oPndCCt9pglxnC7+WMNfUA1Bdng9823 rogid:oPfek+oidG3RSMEDFa1GmO10l109534 intact-crc:2286C27368CCC3A5|rigid:oMD3sLfnwaQE+2t2dKWnLEz0bog false sufficient binding region:94-266 sufficient binding region:230-240 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)