#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02293 uniprotkb:Q04631 intact:EBI-602454|ensembl:ENSRNOP00000010588 intact:EBI-602447 psi-mi:fntb_rat(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:Fntb(gene name)|psi-mi:Fntb(display_short) psi-mi:fnta_rat(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:Fnta(gene name)|psi-mi:Fnta(display_short) psi-mi:"MI:0114"(x-ray crystallography) Gwaltney et al. (2003) pubmed:12657283 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1035966|rcsb pdb:1N9A - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000007660(gene)|ensembl:ENSRNOT00000010588(transcript)|go:"GO:0004311"(farnesyltranstransferase activity)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|go:"GO:0034097"(response to cytokine)|rgd:620119|refseq:NP_742031.1|dip:DIP-6132N|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1FPP|rcsb pdb:1FT1|rcsb pdb:1FT2|rcsb pdb:1FTI|rcsb pdb:1HZ7|rcsb pdb:1JCR|rcsb pdb:1JCS|rcsb pdb:1KZO|rcsb pdb:1KZP|go:"GO:0042060"(wound healing)|rcsb pdb:1KZR|rcsb pdb:1N94|rcsb pdb:1N95|rcsb pdb:1N9A|rcsb pdb:1NI1|rcsb pdb:1NL4|rcsb pdb:1O1R|rcsb pdb:1O1S|rcsb pdb:1O1T|rcsb pdb:1O5M|rcsb pdb:1QBQ|rcsb pdb:1QE2|rcsb pdb:1SA5|rcsb pdb:1TN7|rcsb pdb:1TN8|rcsb pdb:1X81|rcsb pdb:2BED|rcsb pdb:2FTI|rcsb pdb:2R2L|rcsb pdb:2ZIR|rcsb pdb:2ZIS|rcsb pdb:3DPY|rcsb pdb:3E30|rcsb pdb:3E32|rcsb pdb:3E33|rcsb pdb:3E34|rcsb pdb:3EU5|rcsb pdb:3EUV|rcsb pdb:3FTI|rcsb pdb:3KSL|rcsb pdb:3KSQ|rcsb pdb:4GTM|rcsb pdb:4GTO|rcsb pdb:4GTP|rcsb pdb:4GTQ|rcsb pdb:4GTR|reactome:R-RNO-2514859|reactome:R-RNO-9648002 rgd:2625|refseq:NP_036979.1|reactome:R-RNO-9648002|reactome:R-RNO-111465|reactome:R-RNO-2514859|dip:DIP-6131N|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|rcsb pdb:1D8D|rcsb pdb:1D8E|rcsb pdb:1FPP|rcsb pdb:1FT1|rcsb pdb:1FT2|rcsb pdb:1FTI|rcsb pdb:1HZ7|rcsb pdb:1JCR|rcsb pdb:1JCS|rcsb pdb:1KZO|rcsb pdb:1KZP|rcsb pdb:1KZR|rcsb pdb:1N4P|rcsb pdb:1N4Q|rcsb pdb:1N4R|rcsb pdb:1N4S|rcsb pdb:1N94|rcsb pdb:1N95|rcsb pdb:1N9A|rcsb pdb:1NI1|rcsb pdb:1NL4|rcsb pdb:1O1R|rcsb pdb:1O1S|rcsb pdb:1O1T|rcsb pdb:1O5M|rcsb pdb:1QBQ|rcsb pdb:1QE2|rcsb pdb:1S64|rcsb pdb:1SA5|rcsb pdb:1TN7|rcsb pdb:1TN8|rcsb pdb:1TNB|rcsb pdb:1TNO|rcsb pdb:1TNU|rcsb pdb:1TNY|rcsb pdb:1TNZ|rcsb pdb:1X81|rcsb pdb:2BED|rcsb pdb:2FTI|rcsb pdb:2R2L|rcsb pdb:2ZIR|rcsb pdb:2ZIS|rcsb pdb:3DPY|rcsb pdb:3E30|rcsb pdb:3E32|rcsb pdb:3E33|rcsb pdb:3E34|rcsb pdb:3EU5|rcsb pdb:3EUV|rcsb pdb:3FTI|rcsb pdb:3KSL|rcsb pdb:3KSQ|rcsb pdb:3PZ4|rcsb pdb:4GTM|rcsb pdb:4GTO|rcsb pdb:4GTP|rcsb pdb:4GTQ|rcsb pdb:4GTR - - - assembly:dimeric, multimeric|3d-r-factors:working 67.100%, free 62.500%|3d-resolution:3.2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:kKCkAYNev/B1QHIQnWf0hZLviAg10116 rogid:UqizMu5QoGM8WNj6siMYHNrE41Y10116 intact-crc:435865D81D962AA4|rigid:xc1Q/7Kea5mWsuJ+M0yC41IQabw false sufficient binding region:22-423 sufficient binding region:55-369 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)