#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620508|mint:MINT-1786307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786308(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786309(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|figure legend:F1A|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:39F7BF381B6975F5|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false tag:n-n(MINT-1786311)|binding-associated region:640-646(MINT-1786318)|mutation disrupting interaction:642-642(MINT-1786358)|mutation disrupting interaction:646-646(MINT-1786727) binding-associated region:663-754(MINT-1786328)|tag:n-n(MINT-1786322) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9JLU4 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-6271152|uniprotkb:Q9WUY7|uniprotkb:Q9WV47 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan3_rat(display_long)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620583|mint:MINT-1786361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786362(identity) go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|rcsb pdb:2F3N|rcsb pdb:2F44|rcsb pdb:5G4X|rcsb pdb:5O99|rcsb pdb:5OVA|rcsb pdb:5OVC|rcsb pdb:5OVP|rcsb pdb:5OVV|rcsb pdb:6EXJ|reactome:R-RNO-6794361|reactome:R-RNO-8853659|mint:Q9JLU4|rgd:69264|refseq:NP_067708.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:MINT-1786375(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:5f5+bUHHbxnta5KzhCtIoW/+MWk10116 intact-crc:4C4EC641C18D24D2|rigid:nN92qnjdpBDCs9CkcV1UDZEXRkg false binding-associated region:640-646(MINT-1786366)|tag:n-n(MINT-1786373) tag:n-n(MINT-1786383)|binding-associated region:570-664(MINT-1786376) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9QX74 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620557|mint:MINT-1786335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786346(identity) rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-1786336(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116 intact-crc:0697F7A06AF9C769|rigid:BXZhZAH6AitkL3F6tzdNVPFbv2g false binding-associated region:640-646(MINT-1786347)|tag:n-n(MINT-1786354) tag:n-n(MINT-1786344)|binding-associated region:248-342(MINT-1786337) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620642|mint:MINT-1786504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786512(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786505(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:E46ED014494C3A7F|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false tag:n-n(MINT-1786518)|binding-associated region:587-634(MINT-1786520) glutathione s tranferase tag:n-n(MINT-1786510)|binding-associated region:663-757(MINT-1786524) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9QX74 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620616|mint:MINT-1786387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786398(identity) rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-1786388(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116 intact-crc:44FA50A1960F5445|rigid:BXZhZAH6AitkL3F6tzdNVPFbv2g false glutathione s tranferase tag:n-n(MINT-1786406)|mutation disrupting interaction:646-646(MINT-1786408)|binding-associated region:640-646(MINT-1786399) ha tag:n-n(MINT-1786396) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0096"(pull down) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620669|mint:MINT-1786531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786541(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786532(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:61095955E2630100|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false tag:n-n(MINT-1786550)|binding-associated region:640-646(MINT-1786542) glutathione s tranferase tag:n-n(MINT-1786539)|binding-associated region:663-757(MINT-1786533) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620703|mint:MINT-1786415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786423(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786416(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|figure legend:F4|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:45D2722C74EBC2C1|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false tag:n-n(MINT-1786432) binding-associated region:577-753(MINT-1786436)|ha tag:n-n(MINT-1786421) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9QX74 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620726|mint:MINT-1786443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786454(identity) rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-1786444(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116 intact-crc:86269C44A913E84D|rigid:BXZhZAH6AitkL3F6tzdNVPFbv2g false tag:n-n(MINT-1786460) ha tag:n-n(MINT-1786452) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9JLU4 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-6271152|uniprotkb:Q9WUY7|uniprotkb:Q9WV47 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan3_rat(display_long)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620807|mint:MINT-1786487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786495(identity) go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|rcsb pdb:2F3N|rcsb pdb:2F44|rcsb pdb:5G4X|rcsb pdb:5O99|rcsb pdb:5OVA|rcsb pdb:5OVC|rcsb pdb:5OVP|rcsb pdb:5OVV|rcsb pdb:6EXJ|reactome:R-RNO-6794361|reactome:R-RNO-8853659|mint:Q9JLU4|rgd:69264|refseq:NP_067708.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:MINT-1786488(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:5f5+bUHHbxnta5KzhCtIoW/+MWk10116 intact-crc:772A9D0D0A208D5A|rigid:nN92qnjdpBDCs9CkcV1UDZEXRkg false tag:n-n(MINT-1786496) ha tag:n-n(MINT-1786493) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9QX74 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620775|mint:MINT-1786466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786474(identity) rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-1786467(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116 intact-crc:C27480F8B40270A6|rigid:BXZhZAH6AitkL3F6tzdNVPFbv2g false tag:n-n(MINT-1786475) ha tag:n-n(MINT-1786472) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620880|mint:MINT-1786581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786589(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786582(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:EAE95E3982647301|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false binding-associated region:640-646(MINT-1786590)|tag:n-n(MINT-1786598) ha tag:n-n(MINT-1786587) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES28-2 uniprotkb:Q9WV48 intact:EBI-8620514|intact:MINT-1786297 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 psi-mi:q9es28-2(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:Kiaa0142(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:p85SPR(gene name synonym) psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620838|mint:MINT-1786554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-642580(isoform-parent)|mint:MINT-1786555(identity) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786566(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2006/03/18 2014/10/16 rogid:31FAm4EB0CYgAqWUrxl5Aj5P0pU10090 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 intact-crc:D47BE3BF6102059D|rigid:oSXcqXeGOJU0a8X/KUE3hoyZRWo false tag:n-n(MINT-1786564)|binding-associated region:587-634(MINT-1786556) ha tag:n-n(MINT-1786573) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55043 uniprotkb:Q9JLU4 intact:EBI-3649585|ensembl:ENSRNOP00000017947 intact:EBI-6271152|uniprotkb:Q9WUY7|uniprotkb:Q9WV47 psi-mi:arhg7_rat(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Pixb(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym) psi-mi:shan3_rat(display_long)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Prosap2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8621001|mint:MINT-1786639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-41481N|rgd:620624|refseq:NP_001106994.1|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|mint:O55043|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSRNOG00000012934(gene)|ensembl:ENSRNOT00000017947(transcript)|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|rcsb pdb:2AK5|rcsb pdb:2DF6|rcsb pdb:2G6F|rcsb pdb:2P4R|rcsb pdb:2W6B|rcsb pdb:3L4F|rcsb pdb:3QJN|reactome:R-RNO-182971|reactome:R-RNO-193648|reactome:R-RNO-3928664|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:MINT-1786645(identity) go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|rcsb pdb:2F3N|rcsb pdb:2F44|rcsb pdb:5G4X|rcsb pdb:5O99|rcsb pdb:5OVA|rcsb pdb:5OVC|rcsb pdb:5OVP|rcsb pdb:5OVV|rcsb pdb:6EXJ|reactome:R-RNO-6794361|reactome:R-RNO-8853659|mint:Q9JLU4|rgd:69264|refseq:NP_067708.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:MINT-1786640(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5F|comment:mint taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2006/03/18 2014/10/16 rogid:NUPgIOj57QUVRdHzwa3CEjqL+KA10116 rogid:5f5+bUHHbxnta5KzhCtIoW/+MWk10116 intact-crc:8F0BC98E1ED026A1|rigid:CNfr4NQvsxPpsbAjTUZ0VBc1jfY false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9Z272 uniprotkb:O55043 intact:EBI-3842379 intact:EBI-3649585|ensembl:ENSRNOP00000017947 psi-mi:git1_rat(display_long)|uniprotkb:Git1(gene name)|psi-mi:Git1(display_short)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:GRK-interactor 1(gene name synonym) psi-mi:arhg7_rat(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Pixb(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8621023|mint:MINT-1786652 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036770|interpro:IPR037278|interpro:IPR032352|rgd:69331|refseq:NP_114002.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR022018|interpro:IPR013724("Spa2 homology (SHD) of GIT")|rcsb pdb:2JX0|rcsb pdb:2W6A|interpro:IPR038508|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032013"(negative regulation of ARF protein signal transduction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:0007420"(brain development)|rcsb pdb:6IUH|rcsb pdb:6IUI|reactome:R-RNO-3928664|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013423|reactome:R-RNO-9013424|mint:MINT-1786653(identity) dip:DIP-41481N|rgd:620624|refseq:NP_001106994.1|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|mint:O55043|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSRNOG00000012934(gene)|ensembl:ENSRNOT00000017947(transcript)|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|rcsb pdb:2AK5|rcsb pdb:2DF6|rcsb pdb:2G6F|rcsb pdb:2P4R|rcsb pdb:2W6B|rcsb pdb:3L4F|rcsb pdb:3QJN|reactome:R-RNO-182971|reactome:R-RNO-193648|reactome:R-RNO-3928664|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:MINT-1786658(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5F|comment:homomint|comment:mint taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2006/03/18 2014/10/16 rogid:4WyZcIKMxcspKHUNKgYhg6ozk6Y10116 rogid:NUPgIOj57QUVRdHzwa3CEjqL+KA10116 intact-crc:961D93D8BB82BBFD|rigid:VsXZX/UGLldpypQKTrGxSVIqzzo false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9WV48 uniprotkb:O55043 intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100 intact:EBI-3649585|ensembl:ENSRNOP00000017947 psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym) psi-mi:arhg7_rat(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Pixb(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620949|mint:MINT-1786602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1|mint:MINT-1786613(identity) dip:DIP-41481N|rgd:620624|refseq:NP_001106994.1|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|mint:O55043|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSRNOG00000012934(gene)|ensembl:ENSRNOT00000017947(transcript)|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|rcsb pdb:2AK5|rcsb pdb:2DF6|rcsb pdb:2G6F|rcsb pdb:2P4R|rcsb pdb:2W6B|rcsb pdb:3L4F|rcsb pdb:3QJN|reactome:R-RNO-182971|reactome:R-RNO-193648|reactome:R-RNO-3928664|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:MINT-1786603(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5F|comment:homomint|comment:mint taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2006/03/18 2014/10/16 rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116 rogid:NUPgIOj57QUVRdHzwa3CEjqL+KA10116 intact-crc:DF3EF5583AF2ACDD|rigid:Nyf03xyFQkcwDDM451TryUBZzLk false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O55043 uniprotkb:Q9QX74 intact:EBI-3649585|ensembl:ENSRNOP00000017947 intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46 psi-mi:arhg7_rat(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Pixb(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym) psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8620972|mint:MINT-1786626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-41481N|rgd:620624|refseq:NP_001106994.1|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|mint:O55043|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSRNOG00000012934(gene)|ensembl:ENSRNOT00000017947(transcript)|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|rcsb pdb:2AK5|rcsb pdb:2DF6|rcsb pdb:2G6F|rcsb pdb:2P4R|rcsb pdb:2W6B|rcsb pdb:3L4F|rcsb pdb:3QJN|reactome:R-RNO-182971|reactome:R-RNO-193648|reactome:R-RNO-3928664|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:MINT-1786632(identity) rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1|mint:MINT-1786627(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5F|comment:homomint|comment:mint taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2006/03/18 2014/10/16 rogid:NUPgIOj57QUVRdHzwa3CEjqL+KA10116 rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116 intact-crc:7CFB90BBC36FB28D|rigid:ML1ff4ks8wuBRipF4SJUQ7Rhw0A false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O55043 uniprotkb:P35465 intact:EBI-3649585|ensembl:ENSRNOP00000017947 intact:EBI-444379|ensembl:ENSRNOP00000045832|ensembl:ENSRNOP00000073036|uniprotkb:Q62934 psi-mi:arhg7_rat(display_long)|uniprotkb:Arhgef7(gene name)|psi-mi:Arhgef7(display_short)|uniprotkb:Pak3bp(gene name synonym)|uniprotkb:Pixb(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym) psi-mi:pak1_rat(display_long)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p68-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:Protein kinase MUK2(gene name synonym)|uniprotkb:Pak1(gene name)|psi-mi:Pak1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Park et al. (2003) mint:MINT-5216207|pubmed:12626503 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8621052|mint:MINT-1786665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-41481N|rgd:620624|refseq:NP_001106994.1|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099140"(presynaptic actin cytoskeleton organization)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|mint:O55043|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSRNOG00000012934(gene)|ensembl:ENSRNOT00000017947(transcript)|go:"GO:0000322"(storage vacuole)|go:"GO:0001726"(ruffle)|rcsb pdb:2AK5|rcsb pdb:2DF6|rcsb pdb:2G6F|rcsb pdb:2P4R|rcsb pdb:2W6B|rcsb pdb:3L4F|rcsb pdb:3QJN|reactome:R-RNO-182971|reactome:R-RNO-193648|reactome:R-RNO-3928664|reactome:R-RNO-416482|reactome:R-RNO-8980692|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013406|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:MINT-1786671(identity) ensembl:ENSRNOG00000029784(gene)|ensembl:ENSRNOT00000049321(transcript)|ensembl:ENSRNOT00000091952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0005518"(collagen binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0005524"(ATP binding)|go:"GO:0021764"(amygdala development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061534"(gamma-aminobutyric acid secretion, neurotransmission)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061535"(glutamate secretion, neurotransmission)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098597"(observational learning)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|rcsb pdb:1E0A|reactome:R-RNO-202433|reactome:R-RNO-2029482|reactome:R-RNO-2871796|reactome:R-RNO-376172|reactome:R-RNO-389359|reactome:R-RNO-3928662|reactome:R-RNO-3928664|reactome:R-RNO-399954|reactome:R-RNO-445144|reactome:R-RNO-445355|reactome:R-RNO-5218920|reactome:R-RNO-5621575|reactome:R-RNO-5627123|reactome:R-RNO-5687128|reactome:R-RNO-8964616|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013420|reactome:R-RNO-9013423|reactome:R-RNO-9013424|rgd:3250|refseq:NP_058894.1|refseq:XP_006229814.1|refseq:XP_006229815.1|refseq:XP_006229816.1|dip:DIP-32990N|mint:MINT-1786666(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5F|comment:homomint|comment:mint taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2006/03/18 2014/10/16 rogid:NUPgIOj57QUVRdHzwa3CEjqL+KA10116 rogid:wNLimcsV++XEGSFLp+/JSDAJrps10116 intact-crc:B01695AF4E0354A1|rigid:FUNr0JOj3Fw87GOEp2S/FCDF1Y8 false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)