#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O94556 uniprotkb:P50528 intact:EBI-1116472|ensemblfungi:"SPAC6F12.14.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:apc8_schpo(display_long)|uniprotkb:cut23(gene name)|psi-mi:cut23(display_short)|uniprotkb:apc8(gene name synonym)|uniprotkb:SPAC6F12.14(orf name)|uniprotkb:20S cyclosome/APC complex protein apc8(gene name synonym)|uniprotkb:Cell untimely torn protein 23(gene name synonym) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1115981 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3ZN3|rcsb pdb:5FTP|ensemblfungi:SPAC6F12.14(gene)|ensemblfungi:SPAC6F12.14.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|refseq:NP_593300.1|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SPO-983168 refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - - crc64:F11CD0EF9B913917 figure legend:Fig 5B, Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:1VGixeW3PZla68diUHg/2d+aSwA284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:8173180B5335845F|rigid:NR5xODAUbZrXtRD1DkpNCFWJ5Jg false sufficient binding region:17-565 binding-associated region:508-510|binding-associated region:625-627|mutation decreasing interaction:493-493|mutation decreasing interaction:605-605|mutation decreasing interaction:565-565|mutation decreasing interaction:533-533|sufficient binding region:313-683|necessary binding region:534-683 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P78953 uniprotkb:P50528 intact:EBI-1116819|ensemblfungi:"SPCC4B3.15.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:mid1_schpo(display_long)|uniprotkb:mid1(gene name)|psi-mi:mid1(display_short)|uniprotkb:dmf1(gene name synonym)|uniprotkb:SPCC4B3.15(orf name) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1116798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588075.1|ensemblfungi:SPCC4B3.15(gene)|ensemblfungi:SPCC4B3.15.1(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0008289"(lipid binding)|go:"GO:0031097"(medial cortex)|go:"GO:0071341"(medial cortical node)|go:"GO:0090488"(polo box domain specific binding)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:0110085"(mitotic actomyosin contractile ring)|go:"GO:0120104"(mitotic actomyosin contractile ring, proximal layer)|go:"GO:1902406"(mitotic actomyosin contractile ring maintenance)|go:"GO:1902408"(mitotic cytokinesis, site selection)|go:"GO:1903475"(mitotic actomyosin contractile ring assembly)|go:"GO:1903486"(establishment of mitotic actomyosin contractile ring localization)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:4XOH|go:"GO:0031106"(septin ring organization)|reactome:R-SPO-8980692|reactome:R-SPO-9013026|dip:DIP-36604N refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - crc64:CA95FB48A20549B5 crc64:F11CD0EF9B913917 figure legend:Fig. 5B, Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:Vs9oOu41n12eUketBv5y/TqBQdU284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:329A84ACF47B84DA|rigid:20ReRVWHUtiSB/PtpR6le5ND+H8 false sufficient binding region:124-920 sufficient binding region:313-683|necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627|mutation decreasing interaction:498-498|mutation decreasing interaction:533-533 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HGL3 uniprotkb:P50528 intact:EBI-1117052|uniprotkb:P78821|ensemblfungi:"SPBC800.09.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:sum2_schpo(display_long)|uniprotkb:sum2(gene name)|psi-mi:sum2(display_short)|uniprotkb:SPBC800.09(orf name) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117041 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019050|refseq:NP_595110.1|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|ensemblfungi:SPBC800.09(gene)|ensemblfungi:SPBC800.09.1(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0030371"(translation repressor activity)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:1904689"(negative regulation of cytoplasmic translational initiation)|go:"GO:1990124"(messenger ribonucleoprotein complex) refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - - crc64:F11CD0EF9B913917 figure legend:Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:XiX/BMX50Gyx1ZnSMHD6fYxMJyM284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:4418B11FA931D789|rigid:CoSpPwYwbib9OWQDFNCf7s52OJk false - necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627|sufficient binding region:313-683 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50530 uniprotkb:P50528 intact:EBI-1117209|uniprotkb:Q9UTF3|ensemblfungi:"SPAC1B9.02c.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:sck1_schpo(display_long)|uniprotkb:sck1(gene name)|psi-mi:sck1(display_short)|uniprotkb:SPAC1B9.02c(orf name) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SPO-6804757|refseq:NP_593754.1|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017892|interpro:IPR035892|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblfungi:SPAC1B9.02c(gene)|ensemblfungi:SPAC1B9.02c.1(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110034"(negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|reactome:R-SPO-199418|reactome:R-SPO-450385|reactome:R-SPO-5628897|reactome:R-SPO-6804758|reactome:R-SPO-1257604|reactome:R-SPO-1474151|reactome:R-SPO-165158|reactome:R-SPO-165181|reactome:R-SPO-198323|reactome:R-SPO-198693|reactome:R-SPO-203615|reactome:R-SPO-389357|reactome:R-SPO-389513|reactome:R-SPO-392451|reactome:R-SPO-5218920|reactome:R-SPO-6811558|reactome:R-SPO-9009391|reactome:R-SPO-8948751 refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - - crc64:F11CD0EF9B913917 figure legend:Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:6yqIywa4svBUdz4uupGrrNwPruQ284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:514D0841AA9AD6F1|rigid:Vf6/ROIh59v9Ox1aBgi4c8DJO08 false sufficient binding region:464-696 sufficient binding region:313-683|necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9USY4 uniprotkb:P50528 intact:EBI-1117294|uniprotkb:P78967|ensemblfungi:"SPBC1861.02.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:abp2_schpo(display_long)|uniprotkb:abp2(gene name)|psi-mi:abp2(display_short)|uniprotkb:SPBC1861.02(orf name) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018562|refseq:NP_596719.1|ensemblfungi:SPBC1861.02(gene)|ensemblfungi:SPBC1861.02.1(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0044732"(mitotic spindle pole body) refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - - crc64:F11CD0EF9B913917 figure legend:Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:qNimG7KE2O6+jcwI9QVPXUkhvUk284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:F8EC108200B68DC6|rigid:TBJt0iAmaTPfvKEhiZYtV4pSpdM false sufficient binding region:259-527 sufficient binding region:313-683|necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UTR8 uniprotkb:P50528 intact:EBI-1117407|uniprotkb:Q9UTX3|ensemblfungi:"SPAC1006.03c.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:red1_schpo(display_long)|uniprotkb:iss3(gene name synonym)|uniprotkb:SPAC1006.03c(orf name)|uniprotkb:red1(gene name)|psi-mi:red1(display_short) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPAC1006.03c(gene)|ensemblfungi:SPAC1006.03c.1(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033620"(Mei2 nuclear dot complex)|go:"GO:0033621"(nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts)|go:"GO:0043144"("sno(s)RNA processing")|go:"GO:0046872"(metal ion binding)|go:"GO:0071920"(cleavage body)|go:"GO:1902794"(siRNA-independent facultative heterochromatin assembly)|go:"GO:1902801"(regulation of siRNA-independent facultative heterochromatin assembly)|go:"GO:1902802"(regulation of siRNA-dependent facultative heterochromatin assembly)|go:"GO:1990251"(nuclear exosome focus)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990477"(MTREC complex)|interpro:IPR019607|interpro:IPR039278|refseq:NP_594850.2|dip:DIP-36608N refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - crc64:7386E73363CC1AF6 crc64:F11CD0EF9B913917 figure legend:Fig 5B, Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:nQeHNpAJ7P/zyAtf3d+/ILm7XjQ284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:8C28E02C2737A72A|rigid:1aUlXmKlkG+Dh/JYzVMNK6rvCys false sufficient binding region:270-c mutation decreasing interaction:498-498|sufficient binding region:313-683|necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50528 uniprotkb:O14213 intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" intact:EBI-1117724|ensemblfungi:"SPAC6B12.08.1:pep" psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:epr1_schpo(display_long)|uniprotkb:epr1(gene name)|psi-mi:epr1(display_short)|uniprotkb:Meiotically up-regulated gene 185 protein(gene name synonym)|uniprotkb:mug185(gene name synonym)|uniprotkb:SPAC6B12.08(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 refseq:NP_593763.1|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR022755|interpro:IPR003604(Zinc finger, U1-type)|ensemblfungi:SPAC6B12.08(gene)|ensemblfungi:SPAC6B12.08.1(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008270"(zinc ion binding)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061709"(reticulophagy)|go:"GO:0140506"(endoplasmic reticulum-autophagosome adaptor activity)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR036869 - crc64:F11CD0EF9B913917 - figure legend:Fig. 5B, Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 rogid:l6na2m8SGMjrrfeoL0g37JKx/0A284812 intact-crc:6323F0910E57F359|rigid:UzWe9fgQPkuDS0kIzmjgP9G8x9Q false necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627|sufficient binding region:313-683|mutation disrupting interaction:256-256|mutation disrupting interaction:251-251|mutation disrupting interaction:252-252|mutation disrupting interaction:493-493|mutation decreasing interaction:498-498|mutation decreasing interaction:533-533 sufficient binding region:41-380 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O13987 uniprotkb:P50528 intact:EBI-1117930|ensemblfungi:"SPAC26H5.05.1:pep" intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep" psi-mi:yeg5_schpo(display_long)|uniprotkb:SPAC26H5.05(orf name) psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name) psi-mi:"MI:0018"(two hybrid) Reynolds et al. (2003) pubmed:12615979 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1117967 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032991"(protein-containing complex)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|go:"GO:2001279"(regulation of unsaturated fatty acid biosynthetic process)|ensemblfungi:SPAC26H5.05(gene)|ensemblfungi:SPAC26H5.05.1(transcript)|interpro:IPR036770|refseq:NP_594452.1|interpro:IPR002110(Ankyrin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR002909(Cell surface receptor IPT/TIG) refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025 - - crc64:F11CD0EF9B913917 figure legend:Table 2 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/10/25 2014/10/16 rogid:i0SpHVTHD2/jqaGIqkta4uxRa3Q284812 rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812 intact-crc:2AADD0C55389189E|rigid:UeAlP5KQfQn4uMuagelTsQzwNJA false sufficient binding region:533-1151 sufficient binding region:313-683|necessary binding region:534-683|binding-associated region:508-510|binding-associated region:625-627 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)