#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q06604 uniprotkb:P50942 intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wicky et al. (2003) pubmed:12606027|imex:IM-19282 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1173541|imex:IM-19282-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 - - crc64:97B279870DFE6F65 figure legend:No figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/12/01 2014/10/16 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 intact-crc:4D2E391DAFFD53E6|rigid:AFDgV4F65ZL99fQ2q65oDSpOyUc false - binding-associated region:1-588 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q06604 uniprotkb:P50942 intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Wicky et al. (2003) pubmed:12606027|imex:IM-19282 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1173554|imex:IM-19282-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 - - crc64:97B279870DFE6F65 figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/12/01 2014/10/16 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 intact-crc:D97EAEE52382A313|rigid:AFDgV4F65ZL99fQ2q65oDSpOyUc false 35s radiolabel:?-? binding-associated region:1-588(IPR002013)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06604 uniprotkb:P50942 intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Wicky et al. (2003) pubmed:12606027|imex:IM-19282 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1173571|imex:IM-19282-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 - - crc64:97B279870DFE6F65 figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/12/01 2014/10/16 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 intact-crc:3356A1DAF34E8D4A|rigid:AFDgV4F65ZL99fQ2q65oDSpOyUc false ha tag:c-c calmodulin binding peptide plus protein a tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P50942 uniprotkb:Q06604 intact:EBI-28834|uniprotkb:D6W174|ensemblfungi:YNL106C intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W psi-mi:inp52_yeast(display_long)|uniprotkb:YNL106C(locus name)|uniprotkb:N2160(orf name)|uniprotkb:INP52(gene name)|psi-mi:INP52(display_short)|uniprotkb:SJL2(gene name synonym)|uniprotkb:Synaptojanin-like protein 2(gene name synonym) psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wicky et al. (2003) pubmed:12606027|imex:IM-19282 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1173589|imex:IM-19282-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014293.1|sgd:S000005050|dip:DIP-2764N|mint:P50942|ensemblfungi:YNL106C(gene)|ensemblfungi:YNL106C_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043332"(mating projection tip)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-8856828 sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) - crc64:97B279870DFE6F65 - figure legend:Fig. 1C|comment:"The full length SAC1 domain is required for the interaction since deleting the highly conserved CX5(T/S) motif impairs the interaction."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/12/01 2014/10/16 rogid:r08JCOgVbZLSAZaMWTAD3Enrkww559292 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 intact-crc:B91203BD23BC8AC8|rigid:AFDgV4F65ZL99fQ2q65oDSpOyUc false binding-associated region:1-588(IPR002013) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12271 uniprotkb:Q06604 intact:EBI-36688|uniprotkb:D6W2G8|ensemblfungi:YOR109W intact:EBI-37047|uniprotkb:D6W4H2|ensemblfungi:YPR171W psi-mi:inp53_yeast(display_long)|uniprotkb:Synaptojanin-like protein 3(gene name synonym)|uniprotkb:Suppressor of PMA1 protein 2(gene name synonym)|uniprotkb:INP53(gene name)|psi-mi:INP53(display_short)|uniprotkb:SJL3(gene name synonym)|uniprotkb:SOP2(gene name synonym)|uniprotkb:YOR3231w(orf name)|uniprotkb:YOR109W(locus name) psi-mi:bsp1_yeast(display_long)|uniprotkb:BSP1(gene name)|psi-mi:BSP1(display_short)|uniprotkb:YPR171W(locus name)|uniprotkb:Binding of synaptojanin polyphosphoinositide phosphatase domain protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Wicky et al. (2003) pubmed:12606027|imex:IM-19282 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1173596|imex:IM-19282-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005635|refseq:NP_014752.3|mint:Q12271|dip:DIP-2555N|ensemblfungi:YOR109W(gene)|ensemblfungi:YOR109W_mRNA(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|reactome:R-SCE-1660499|reactome:R-SCE-1855183|reactome:R-SCE-1855204|reactome:R-SCE-8856828 sgd:S000006375|refseq:NP_015497.1|mint:Q06604|dip:DIP-2756N|ensemblfungi:YPR171W(gene)|ensemblfungi:YPR171W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030479"(actin cortical patch)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0051666"(actin cortical patch localization) - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/12/01 2014/10/16 rogid:99bi0oSA0ftzn4Tyu4QHo0OKgZI559292 rogid:JdYSQGySUARnz4EQtxR5m6E4SD4559292 intact-crc:1521E3AAAFEEE344|rigid:vwPSe1j4GFZjleRhh0g6QxW2PjQ false binding-associated region:1-563(IPR002013) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)