#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12504 uniprotkb:Q9NWF9-3 intact:EBI-779991 intact:EBI-723337 psi-mi:vif_hv1n5(display_long)|uniprotkb:SOR protein(gene name synonym)|uniprotkb:vif(gene name)|psi-mi:vif(display_short) psi-mi:q9nwf9-3(display_long)|uniprotkb:RNF216(gene name)|psi-mi:RNF216(display_short)|uniprotkb:TRIAD3(gene name synonym)|uniprotkb:UBCE7IP1(gene name synonym)|uniprotkb:ZIN(gene name synonym)|uniprotkb:RING finger protein 216(gene name synonym)|uniprotkb:Triad domain-containing protein 3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger protein inhibiting NF-kappa-B(gene name synonym)|uniprotkb:ZIN(isoform synonym)|uniprotkb:TRIAD3(isoform synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF216(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lake et al. (2003) pubmed:12600646|mint:MINT-6655445 taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780038 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-36069N|go:"GO:0003723"(RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019058"(viral life cycle)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR000475("Retroviral Vif (Viral infectivity) protein")|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:4N9F|rcsb pdb:6NIL intact:EBI-723313(ub7i1_human) - - isoform-comment:4 different alternatively spliced mRNAs code for this protein isoform. comment:"HIV-1 pNL4.3 corresponding to HIV M19921 (HV1N5) was used to amplify vif."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:H/Ja1HuLpE2b8ly9aKuonp+exC011698 rogid:S2i4kF0xUKaTNkGY0I6W182sVe49606 intact-crc:E35A0392A3C8286C|rigid:NMwMAv12jw0S7JI6cJT3juRga8Q false mutation disrupting interaction:105-107|necessary binding region:28-192 sufficient binding region:142-359 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21673 uniprotkb:P12504 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 intact:EBI-779991 psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:vif_hv1n5(display_long)|uniprotkb:SOR protein(gene name synonym)|uniprotkb:vif(gene name)|psi-mi:vif(display_short) psi-mi:"MI:0018"(two hybrid) Lake et al. (2003) pubmed:12600646|mint:MINT-6655445 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:11698(hv1n5)|taxid:11698("Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-780054 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N dip:DIP-36069N|go:"GO:0003723"(RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019058"(viral life cycle)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|interpro:IPR000475("Retroviral Vif (Viral infectivity) protein")|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:4N9F|rcsb pdb:6NIL - - - comment:"HIV-1 pNL4.3 corresponding to HIV M19921 (HV1N5) was used to amplify vif."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/01/10 2014/10/16 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rogid:H/Ja1HuLpE2b8ly9aKuonp+exC011698 intact-crc:A004CD3084B2540D|rigid:7YXwBzjDpvTK34cLfyK+RNuLXLo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)