#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35330 uniprotkb:P26043 intact:EBI-1035485|uniprotkb:Q9D8Q4|ensembl:ENSMUSP00000001055|intact:EBI-15579640 intact:EBI-647737|uniprotkb:Q3TS85|uniprotkb:Q9QW27|ensembl:ENSMUSP00000000590|ensembl:ENSMUSP00000128249 psi-mi:icam2_mouse(display_long)|uniprotkb:Icam2(gene name)|psi-mi:Icam2(display_short)|uniprotkb:Icam-2(gene name synonym)|uniprotkb:Lymphocyte function-associated AG-1 counter-receptor(gene name synonym) psi-mi:radi_mouse(display_long)|uniprotkb:ESP10(gene name synonym)|uniprotkb:Rdx(gene name)|psi-mi:Rdx(display_short) psi-mi:"MI:0114"(x-ray crystallography) Hamada et al. (2003) pubmed:12554651 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1035503|rcsb pdb:1J19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034624.1|refseq:XP_006532366.1|ensembl:ENSMUSG00000001029(gene)|ensembl:ENSMUST00000001055(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007155"(cell adhesion)|go:"GO:0032154"(cleavage furrow)|go:"GO:0071944"(cell periphery)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003987(Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal)|interpro:IPR013768(Intercellular adhesion molecule, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015653(Intercellular adhesion molecule 2)|interpro:IPR036179|rcsb pdb:1J19|reactome:R-MMU-198933|reactome:R-MMU-216083|reactome:R-MMU-5621575|dip:DIP-29094N refseq:NP_001098086.1|refseq:NP_033067.2|dip:DIP-29091N|ensembl:ENSMUSG00000032050(gene)|ensembl:ENSMUST00000000590(transcript)|ensembl:ENSMUST00000163153(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032420"(stereocilium)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0045176"(apical protein localization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903392"(negative regulation of adherens junction organization)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26043|rcsb pdb:1GC6|rcsb pdb:1GC7|rcsb pdb:1J19|rcsb pdb:2D10|rcsb pdb:2D11|rcsb pdb:2D2Q|rcsb pdb:2EMS|rcsb pdb:2EMT|rcsb pdb:2YVC|rcsb pdb:2ZPY|rcsb pdb:3X23|reactome:R-MMU-437239 - - - assembly:dimeric, multimeric|3d-r-factors:working 77.200%, free 76.100%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:NDaAVB3g65OyeYhYY78J9/9hSTk10090 rogid:d7wqsdTau9b92O3q6LW+/pyKL1w10090 intact-crc:B633EB591839EDC3|rigid:RSSSoGABmQPg2aVncfEw6yPy6ZI false sufficient binding region:253-268 sufficient binding region:1-310 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)