#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17150 uniprotkb:Q13651 intact:EBI-1033736|uniprotkb:Q7M6T2|uniprotkb:Q9J7C4 intact:EBI-1031656|uniprotkb:B0YJ27|uniprotkb:A8K6I0|ensembl:ENSP00000227752 psi-mi:il10h_hcmva(display_long)|uniprotkb:UL111A(gene name)|psi-mi:UL111A(display_short) psi-mi:i10r1_human(display_long)|uniprotkb:IL10RA(gene name)|psi-mi:IL10RA(display_short)|uniprotkb:IL10R(gene name synonym)|uniprotkb:Interleukin-10 receptor subunit 1(gene name synonym)|uniprotkb:CDw210a(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Jones et al. (2002) pubmed:12093920 taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1033751|rcsb pdb:1LQS - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039673"(evasion by virus of host dendritic cell activity)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR012352(Interleukin-10, additional helical)|interpro:IPR020423|interpro:IPR020443|rcsb pdb:1LQS|dip:DIP-36823N refseq:NP_001549.2|go:"GO:0004920"(interleukin-10 receptor activity)|ensembl:ENSG00000110324(gene)|ensembl:ENST00000227752(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019969"(interleukin-10 binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0070086"(ubiquitin-dependent endocytosis)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|rcsb pdb:1J7V|rcsb pdb:1LQS|rcsb pdb:1Y6K|rcsb pdb:1Y6M|rcsb pdb:1Y6N|rcsb pdb:5IXI|rcsb pdb:6X93|reactome:R-HSA-6783783|dip:DIP-3512N - comment:This is the only entry of this protein in UniProt. - assembly:octameric, multimeric|3d-r-factors:working 75.600%, free 70.600%|3d-resolution:2.7A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:SBpuYPBQ7bVKiWHA3Y82P+sd3h010360 rogid:sMAPIcNDOtzRHrmx79PMcP9jDRA9606 intact-crc:61768F2F197643A7|rigid:1tPIn7M29vwQ0vKVi+COITLzBLQ false sufficient binding region:27-175 sufficient binding region:22-235 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)