#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38713	uniprotkb:P45818	intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W	intact:EBI-15686|uniprotkb:D6VTY1|ensemblfungi:YGL171W	psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short)	psi-mi:rok1_yeast(display_long)|uniprotkb:ROK1(gene name)|psi-mi:ROK1(display_short)|uniprotkb:YGL171W(locus name)|uniprotkb:G1651(orf name)|uniprotkb:Rescuer of KEM1 protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Park et al. (2002)	pubmed:12054531|imex:IM-19045	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-969738|imex:IM-19045-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N	refseq:NP_011344.1|sgd:S000003139|ensemblfungi:YGL171W(gene)|ensemblfungi:YGL171W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|reactome:R-SCE-6791226|dip:DIP-5111N|mint:P45818	go:"GO:0004004"	crc64:B1AD1210EFFB9AFE	crc64:CACB950B8A15D5A2	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/12	2014/10/16	rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292	rogid:Id8imuuTKPSw1r4qwGClHrYAxpQ559292	intact-crc:FA5432C6291C4A58|rigid:oMdYbRSz87mk8AxF5F0Is71+Ra8	false	-	binding-associated region:329-564	-	-	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)
uniprotkb:P45818	uniprotkb:Q12099	intact:EBI-15686|uniprotkb:D6VTY1|ensemblfungi:YGL171W	intact:EBI-6776|uniprotkb:D6VS07|ensemblfungi:YDR021W	psi-mi:rok1_yeast(display_long)|uniprotkb:ROK1(gene name)|psi-mi:ROK1(display_short)|uniprotkb:YGL171W(locus name)|uniprotkb:G1651(orf name)|uniprotkb:Rescuer of KEM1 protein 1(gene name synonym)	psi-mi:fal1_yeast(display_long)|uniprotkb:FAL1(gene name)|psi-mi:FAL1(display_short)|uniprotkb:YDR021W(locus name)|uniprotkb:YD9335.07(orf name)|uniprotkb:PZC399(orf name)|uniprotkb:Translation initiation factor four A-like protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Park et al. (2002)	pubmed:12054531|imex:IM-19045	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-969750|imex:IM-19045-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011344.1|sgd:S000003139|ensemblfungi:YGL171W(gene)|ensemblfungi:YGL171W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|reactome:R-SCE-6791226|dip:DIP-5111N|mint:P45818	refseq:NP_010304.3|sgd:S000002428|dip:DIP-4516N|mint:Q12099|ensemblfungi:YDR021W(gene)|ensemblfungi:YDR021W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097078"(FAL1-SGD1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-SCE-429947|reactome:R-SCE-975957	go:"GO:0004004"	crc64:CACB950B8A15D5A2	crc64:76A3441728D21253	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/12	2014/10/16	rogid:Id8imuuTKPSw1r4qwGClHrYAxpQ559292	rogid:DpSu5iJlZBXbp7bqquc7csKCN+Y559292	intact-crc:2A805C16C6478693|rigid:8oEd/eZHAwJdxG3d8/Fwhcy+gEk	false	binding-associated region:1-328	-	-	-	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)
uniprotkb:P45818	uniprotkb:P38713	intact:EBI-15686|uniprotkb:D6VTY1|ensemblfungi:YGL171W	intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W	psi-mi:rok1_yeast(display_long)|uniprotkb:ROK1(gene name)|psi-mi:ROK1(display_short)|uniprotkb:YGL171W(locus name)|uniprotkb:G1651(orf name)|uniprotkb:Rescuer of KEM1 protein 1(gene name synonym)	psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short)	psi-mi:"MI:0018"(two hybrid)	Park et al. (2002)	pubmed:12054531|imex:IM-19045	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-997902|imex:IM-19045-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011344.1|sgd:S000003139|ensemblfungi:YGL171W(gene)|ensemblfungi:YGL171W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|reactome:R-SCE-6791226|dip:DIP-5111N|mint:P45818	ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N	go:"GO:0004004"	crc64:CACB950B8A15D5A2	crc64:B1AD1210EFFB9AFE	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/12	2014/10/16	rogid:Id8imuuTKPSw1r4qwGClHrYAxpQ559292	rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292	intact-crc:D77DF1C04CA6014A|rigid:oMdYbRSz87mk8AxF5F0Is71+Ra8	false	-	-	-	-	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)	psi-mi:"MI:0080"(partial dna sequence identification by hybridization)
uniprotkb:P45818	uniprotkb:P38713	intact:EBI-15686|uniprotkb:D6VTY1|ensemblfungi:YGL171W	intact:EBI-12630|uniprotkb:D3DL23|ensemblfungi:YHR073W	psi-mi:rok1_yeast(display_long)|uniprotkb:ROK1(gene name)|psi-mi:ROK1(display_short)|uniprotkb:YGL171W(locus name)|uniprotkb:G1651(orf name)|uniprotkb:Rescuer of KEM1 protein 1(gene name synonym)	psi-mi:osh3_yeast(display_long)|uniprotkb:YHR073W(locus name)|uniprotkb:OSH3(gene name)|psi-mi:OSH3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2002)	pubmed:12054531|imex:IM-19045	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-969779|imex:IM-19045-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011344.1|sgd:S000003139|ensemblfungi:YGL171W(gene)|ensemblfungi:YGL171W_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|reactome:R-SCE-6791226|dip:DIP-5111N|mint:P45818	ensemblfungi:YHR073W_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008289"(lipid binding)|go:"GO:0010922"(positive regulation of phosphatase activity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|ensemblfungi:YHR073W(gene)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036598|interpro:IPR037239|interpro:IPR041680|rcsb pdb:4IAP|rcsb pdb:4IC4|rcsb pdb:4INQ|reactome:R-SCE-192105|go:"GO:0035621"(ER to Golgi ceramide transport)|refseq:NP_011940.1|sgd:S000001115|mint:P38713|dip:DIP-2148N	go:"GO:0004004"	crc64:CACB950B8A15D5A2	crc64:B1AD1210EFFB9AFE	figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/12	2014/10/16	rogid:Id8imuuTKPSw1r4qwGClHrYAxpQ559292	rogid:fhlpdXizvjnmxMYAM+Z/6AYPT4Y559292	intact-crc:5CC50F7FBC502549|rigid:oMdYbRSz87mk8AxF5F0Is71+Ra8	false	-	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)