#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00482	uniprotkb:O60869	intact:EBI-781320|uniprotkb:B4E2P3|uniprotkb:O95642|uniprotkb:Q147U3|ensembl:ENSP00000356331	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:nr5a2_human(display_long)|uniprotkb:Alpha-1-fetoprotein transcription factor(gene name synonym)|uniprotkb:Hepatocytic transcription factor(gene name synonym)|uniprotkb:B1-binding factor(gene name synonym)|uniprotkb:CYP7A promoter-binding factor(gene name synonym)|uniprotkb:Liver receptor homolog 1(gene name synonym)|uniprotkb:NR5A2(gene name)|psi-mi:NR5A2(display_short)|uniprotkb:B1F(gene name synonym)|uniprotkb:CPF(gene name synonym)|uniprotkb:FTF(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781351|imex:IM-19138-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005245119.1|refseq:NP_003813.1|refseq:NP_995582.1|refseq:XP_011507684.1|refseq:NP_001263393.1|dip:DIP-37952N|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|mint:O00482|rcsb pdb:1YOK|rcsb pdb:1YUC|rcsb pdb:1ZDU|rcsb pdb:2A66|rcsb pdb:3PLZ|rcsb pdb:3TX7|rcsb pdb:4DOR|rcsb pdb:4DOS|rcsb pdb:4IS8|rcsb pdb:4ONI|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4RWV|rcsb pdb:5L0M|rcsb pdb:5L11|rcsb pdb:5SYZ|rcsb pdb:5UNJ|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6VC2|rcsb pdb:6VIF|reactome:R-HSA-210747|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-9018519|ensembl:ENSG00000116833(gene)|ensembl:ENST00000367362(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009888"(tissue development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061113"(pancreas morphogenesis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	comment:"Experiments with deletion mutants of LRH-1 found that the DE domain(AA 144-501) was fully dispensable for its interaction with MBF-1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:3HpmBpnydn2/WT1CToT/tjRrJ189606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:6EC3CFBD7882A050|rigid:vE9irPB8Xjcw98N+eubzSNe2RCY	false	binding-associated region:1-144|35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19793	uniprotkb:O60869	intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781426|imex:IM-19138-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:1055B8635718BC52|rigid:N1ACvAcCZnX3E0MfAXG5mN3Z38g	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60869	uniprotkb:O00482	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	intact:EBI-781320|uniprotkb:B4E2P3|uniprotkb:O95642|uniprotkb:Q147U3|ensembl:ENSP00000356331	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:nr5a2_human(display_long)|uniprotkb:Alpha-1-fetoprotein transcription factor(gene name synonym)|uniprotkb:Hepatocytic transcription factor(gene name synonym)|uniprotkb:B1-binding factor(gene name synonym)|uniprotkb:CYP7A promoter-binding factor(gene name synonym)|uniprotkb:Liver receptor homolog 1(gene name synonym)|uniprotkb:NR5A2(gene name)|psi-mi:NR5A2(display_short)|uniprotkb:B1F(gene name synonym)|uniprotkb:CPF(gene name synonym)|uniprotkb:FTF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781466|imex:IM-19138-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	refseq:XP_005245119.1|refseq:NP_003813.1|refseq:NP_995582.1|refseq:XP_011507684.1|refseq:NP_001263393.1|dip:DIP-37952N|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016355(Orphan nuclear receptor Fushi-tarazu factor 1)|interpro:IPR035500|mint:O00482|rcsb pdb:1YOK|rcsb pdb:1YUC|rcsb pdb:1ZDU|rcsb pdb:2A66|rcsb pdb:3PLZ|rcsb pdb:3TX7|rcsb pdb:4DOR|rcsb pdb:4DOS|rcsb pdb:4IS8|rcsb pdb:4ONI|rcsb pdb:4PLD|rcsb pdb:4PLE|rcsb pdb:4RWV|rcsb pdb:5L0M|rcsb pdb:5L11|rcsb pdb:5SYZ|rcsb pdb:5UNJ|rcsb pdb:6OQX|rcsb pdb:6OQY|rcsb pdb:6OR1|rcsb pdb:6VC2|rcsb pdb:6VIF|reactome:R-HSA-210747|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-9018519|ensembl:ENSG00000116833(gene)|ensembl:ENST00000367362(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009888"(tissue development)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042592"(homeostatic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061113"(pancreas morphogenesis)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rogid:3HpmBpnydn2/WT1CToT/tjRrJ189606	intact-crc:227DE31EC42DB78E|rigid:vE9irPB8Xjcw98N+eubzSNe2RCY	false	glutathione s tranferase tag:?-?|binding-associated region:37-113	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13133	uniprotkb:O60869	intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781475|imex:IM-19138-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:06E103287882E968|rigid:aRl9w7Nrmlge1L/J9AIHvWu27qA	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|binding-associated region:37-113	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37231	uniprotkb:O60869	intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781497|imex:IM-19138-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:040A704903AC4826|rigid:P2ErwRQ+HRvKQL9nuxeyNt7CiW4	false	35s radiolabel:?-?	glutathione s tranferase tag:?-?|binding-associated region:37-113	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37231	uniprotkb:O60869	intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0096"(pull down)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781420|imex:IM-19138-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	comment:The interaction between PPAR-gamma and MBF-1 was not affected by the presence of the synthetic PPAR-gamma ligand rosiglitazone.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:A45301623AB7B0DC|rigid:P2ErwRQ+HRvKQL9nuxeyNt7CiW4	false	binding-associated region:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q09472	uniprotkb:P37231	intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253	intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820	psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym)	psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781445|imex:IM-19138-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)	refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606	rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606	intact-crc:FA1F48ECD34E27A1|rigid:8ne6ZH9asBor4EHWmtLyXktco/c	false	glutathione s tranferase tag:?-?	binding-associated region:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q13133	uniprotkb:O60869	intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0096"(pull down)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781379|imex:IM-19138-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:21E5D80DBE1EBA14|rigid:aRl9w7Nrmlge1L/J9AIHvWu27qA	false	binding-associated region:161-447|35s radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13133	uniprotkb:O60869	intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0018"(two hybrid)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781599|imex:IM-19138-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	comment:A 2.5-fold induction of luciferase activity was produced.|comment:"Presence of the ligand 22(R)-hydroxycholesterol was required for the interaction to occur."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells)	-	2006/01/13	2014/10/16	rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:B29B8236395676E7|rigid:aRl9w7Nrmlge1L/J9AIHvWu27qA	false	binding-associated region:161-447	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P37231	uniprotkb:O60869	intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0018"(two hybrid)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781612|imex:IM-19138-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	comment:A 10-fold induction of luciferase activity occurred.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells)	-	2006/01/13	2014/10/16	rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:BB175476C920E8C1|rigid:P2ErwRQ+HRvKQL9nuxeyNt7CiW4	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13133	uniprotkb:O60869	intact:EBI-781356|uniprotkb:A8K3J9|uniprotkb:Q96H87|uniprotkb:D3DQR1|uniprotkb:Q8IW13|ensembl:ENSP00000387946|ensembl:ENSP00000420656	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:nr1h3_human(display_long)|uniprotkb:Liver X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group H member 3(gene name synonym)|uniprotkb:NR1H3(gene name)|psi-mi:NR1H3(display_short)|uniprotkb:LXRA(gene name synonym)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0018"(two hybrid)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781627|imex:IM-19138-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006718175.1|refseq:XP_006718176.1|refseq:XP_006718178.1|refseq:XP_006718179.1|refseq:NP_001123574.1|refseq:NP_001123573.1|refseq:NP_005684.2|refseq:XP_011518107.1|refseq:XP_005252770.1|refseq:XP_005252762.1|refseq:XP_005252763.1|refseq:XP_005252764.1|refseq:XP_005252766.1|refseq:XP_005252767.1|refseq:XP_016872547.1|ensembl:ENSG00000025434(gene)|ensembl:ENST00000441012(transcript)|ensembl:ENST00000467728(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032369"(negative regulation of lipid transport)|go:"GO:0032376"(positive regulation of cholesterol transport)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032570"(response to progesterone)|go:"GO:0032810"(sterol response element binding)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090341"(negative regulation of secretion of lysosomal enzymes)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR023257|interpro:IPR035500|mint:Q13133|rcsb pdb:1UHL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:5HJS|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8866427|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9623433|reactome:R-HSA-9632974	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	comment:MBF-1 coactivates the AF-2 function of LXR-alpha - however little enhancement of transcription can be seen in the absence of ligand.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells)	-	2006/01/13	2014/10/16	rogid:o1qZ/nvjBXMWVvnnwindfL0HBFE9606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	intact-crc:B37D72394AF2E3A5|rigid:aRl9w7Nrmlge1L/J9AIHvWu27qA	false	binding-associated region:161-447	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60869	uniprotkb:P37231	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	intact:EBI-781384|uniprotkb:Q96J12|uniprotkb:O00684|uniprotkb:O00710|uniprotkb:O14515|uniprotkb:Q15178|uniprotkb:Q15179|uniprotkb:Q15180|uniprotkb:Q15832|uniprotkb:Q86U60|uniprotkb:A8K3G6|uniprotkb:B5BUA1|uniprotkb:Q0QJH8|ensembl:ENSP00000287820	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:pparg_human(display_long)|uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym)|uniprotkb:PPARG(gene name)|psi-mi:PPARG(display_short)|uniprotkb:NR1C3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781653|imex:IM-19138-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	refseq:NP_005028.4|refseq:NP_056953.2|refseq:NP_619725.2|refseq:NP_619726.2|refseq:XP_011532143.1|dip:DIP-35528N|ensembl:ENSG00000132170(gene)|ensembl:ENST00000287820(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004955"(prostaglandin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010887"(negative regulation of cholesterol storage)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048469"(cell maturation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060392"(negative regulation of SMAD protein signal transduction)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060694"(regulation of cholesterol transporter activity)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903845"(negative regulation of cellular response to transforming growth factor beta stimulus)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003074(Peroxisome proliferator-activated receptor)|interpro:IPR003077(Peroxisome proliferator-activated receptor, gamma)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR022590|interpro:IPR035500|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1I7I|rcsb pdb:1K74|rcsb pdb:1KNU|rcsb pdb:1NYX|rcsb pdb:1PRG|rcsb pdb:1RDT|rcsb pdb:1WM0|rcsb pdb:1ZEO|rcsb pdb:1ZGY|rcsb pdb:2ATH|rcsb pdb:2F4B|rcsb pdb:2FVJ|rcsb pdb:2G0G|rcsb pdb:2G0H|rcsb pdb:2GTK|rcsb pdb:2HFP|rcsb pdb:2HWQ|rcsb pdb:2HWR|rcsb pdb:2I4J|rcsb pdb:2I4P|rcsb pdb:2I4Z|rcsb pdb:2OM9|rcsb pdb:2P4Y|rcsb pdb:2POB|rcsb pdb:2PRG|rcsb pdb:2Q59|rcsb pdb:2Q5P|rcsb pdb:2Q5S|rcsb pdb:2Q61|rcsb pdb:2Q6R|rcsb pdb:2Q6S|rcsb pdb:2Q8S|rcsb pdb:2QMV|rcsb pdb:2VST|rcsb pdb:2VV0|rcsb pdb:2VV1|rcsb pdb:2VV2|rcsb pdb:2VV3|rcsb pdb:2VV4|rcsb pdb:2XKW|rcsb pdb:2YFE|rcsb pdb:2ZK0|rcsb pdb:2ZK1|rcsb pdb:2ZK2|rcsb pdb:2ZK3|rcsb pdb:2ZK4|rcsb pdb:2ZK5|rcsb pdb:2ZK6|rcsb pdb:2ZNO|rcsb pdb:2ZVT|rcsb pdb:3ADS|rcsb pdb:3ADT|rcsb pdb:3ADU|rcsb pdb:3ADV|rcsb pdb:3ADW|rcsb pdb:3ADX|rcsb pdb:3AN3|rcsb pdb:3AN4|rcsb pdb:3B0Q|rcsb pdb:3B0R|rcsb pdb:3B1M|rcsb pdb:3B3K|rcsb pdb:3BC5|rcsb pdb:3CDP|rcsb pdb:3CDS|rcsb pdb:3CS8|rcsb pdb:3CWD|rcsb pdb:3D6D|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3ET0|rcsb pdb:3ET3|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3G9E|rcsb pdb:3GBK|rcsb pdb:3H0A|rcsb pdb:3HO0|rcsb pdb:3HOD|rcsb pdb:3IA6|rcsb pdb:3K8S|rcsb pdb:3KMG|rcsb pdb:3LMP|rcsb pdb:3NOA|rcsb pdb:3OSI|rcsb pdb:3OSW|rcsb pdb:3PBA|rcsb pdb:3PO9|rcsb pdb:3PRG|rcsb pdb:3QT0|rcsb pdb:3R5N|rcsb pdb:3R8A|rcsb pdb:3R8I|rcsb pdb:3S9S|rcsb pdb:3SZ1|rcsb pdb:3T03|rcsb pdb:3TY0|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:3V9Y|rcsb pdb:3VJH|rcsb pdb:3VJI|rcsb pdb:3VN2|rcsb pdb:3VSO|rcsb pdb:3VSP|rcsb pdb:3WJ4|rcsb pdb:3WJ5|rcsb pdb:3WMH|rcsb pdb:3X1H|rcsb pdb:3X1I|rcsb pdb:4A4V|rcsb pdb:4A4W|rcsb pdb:4CI5|rcsb pdb:4E4K|rcsb pdb:4E4Q|rcsb pdb:4EM9|rcsb pdb:2VSR|rcsb pdb:4EMA|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4HEE|rcsb pdb:4JAZ|rcsb pdb:4JL4|rcsb pdb:4L96|rcsb pdb:4L98|rcsb pdb:4O8F|rcsb pdb:4OJ4|rcsb pdb:4PRG|rcsb pdb:4PVU|rcsb pdb:4PWL|rcsb pdb:4R06|rcsb pdb:4R2U|rcsb pdb:4R6S|rcsb pdb:4XLD|rcsb pdb:4XTA|rcsb pdb:4XUH|rcsb pdb:4XUM|rcsb pdb:4Y29|rcsb pdb:4YT1|rcsb pdb:5AZV|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5F9B|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HZC|rcsb pdb:5JI0|rcsb pdb:5LSG|rcsb pdb:5TTO|rcsb pdb:5TWO|rcsb pdb:5U5L|rcsb pdb:5UGM|rcsb pdb:5WQX|rcsb pdb:5WR0|rcsb pdb:5WR1|rcsb pdb:5Y2O|rcsb pdb:5Y2T|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6AN1|rcsb pdb:6AUG|rcsb pdb:6AVI|rcsb pdb:6C1I|rcsb pdb:6C5Q|rcsb pdb:6C5T|rcsb pdb:6D3E|rcsb pdb:6D8X|rcsb pdb:6D94|rcsb pdb:6DBH|rcsb pdb:6DCU|rcsb pdb:6DGL|rcsb pdb:6DGO|rcsb pdb:6DGP|rcsb pdb:6DGQ|rcsb pdb:6DGR|rcsb pdb:6DH9|rcsb pdb:6DHA|rcsb pdb:6E5A|rcsb pdb:6ENQ|rcsb pdb:6F2L|rcsb pdb:6FZF|rcsb pdb:6FZG|rcsb pdb:6FZJ|rcsb pdb:6FZP|rcsb pdb:6FZY|rcsb pdb:6ICJ|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6JEY|rcsb pdb:6JF0|rcsb pdb:6JQ7|rcsb pdb:6K0T|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L89|rcsb pdb:6L8B|rcsb pdb:6MCZ|rcsb pdb:6MD0|rcsb pdb:6MD1|rcsb pdb:6MD2|rcsb pdb:6MD4|rcsb pdb:6MS7|rcsb pdb:6O67|rcsb pdb:6O68|rcsb pdb:6ONI|rcsb pdb:6ONJ|rcsb pdb:6PDZ|rcsb pdb:6QJ5|rcsb pdb:6T1S|rcsb pdb:6T1V|rcsb pdb:6T6B|rcsb pdb:6T9C|rcsb pdb:6TDC|rcsb pdb:6TSG|rcsb pdb:6VZL|rcsb pdb:6VZM|rcsb pdb:6VZN|rcsb pdb:6VZO|rcsb pdb:6Y3U|rcsb pdb:6ZLY|rcsb pdb:7AHJ|rcsb pdb:7AWC|rcsb pdb:7AWD|rcsb pdb:7EFQ|rcsb pdb:7JQG|rcsb pdb:7LOT|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-8943724|reactome:R-HSA-9022707	-	-	-	comment:MBF-1 coactivates the AF-2 function of PPAR-gamma - however little enhancement of transcription can be seen in the absence of ligand.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9986(rabit-rk13)|taxid:9986(rk13 cell line originating from rabbit kidney epithelial cells)	-	2006/01/13	2014/10/16	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rogid:HdszD4mfXGBad/qiDqQQJtATY2I9606	intact-crc:80631CA01350EAD8|rigid:P2ErwRQ+HRvKQL9nuxeyNt7CiW4	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60869	uniprotkb:P20226	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brendel et al. (2002)	pubmed:12040021|imex:IM-19138	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-781665|imex:IM-19138-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/01/13	2014/10/16	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:AFDC4D59660308D0|rigid:FKOEEe6eU+nS0J48icKcTexmuvk	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)